Click here to switch to the map view.

The map label for this gene is dgoR [H]

Identifier: 77460365

GI number: 77460365

Start: 4683354

End: 4684070

Strand: Reverse

Name: dgoR [H]

Synonym: Pfl01_4144

Alternate gene names: 77460365

Gene position: 4684070-4683354 (Counterclockwise)

Preceding gene: 77460366

Following gene: 77460364

Centisome position: 72.75

GC content: 64.16

Gene sequence:

>717_bases
ATGTCGAGCAGTTTTCACGCATCAACGGTTGACTGGCTGGGCGCCTGGATTGCTGCCGGCCAGGTGAAGCCGGGGCAGGC
GATCAAGGTCGAGGCCGATCTGGGCGAGCAGCTCGGGGTCAGCCGCACCGTGATCCGCGAAGCCATCAAGACTCTGGTCG
CCAAAGGCATGCTCGAAGTCGGGCCGAAAGTCGGCACGCGGGTGCTGCCGATCAAGCGCTGGAACCTGTTCGATCCGCAA
GTCGTGGGCTGGCTGTCACGCAGCGGCCTGCCGGAAAATTTCGTCGATGACCTGCTCGACCTGCGCCGCACCATCGAACC
GATGGCGGTGCGCTGGGCCTGCGAGCGGGCGACCGTTGAACAGGTGCAAGCCGTGCGGCAGGCCTACAACGCGCTGGAAC
GGGCGGTCGACAGCGGCATCGATTACAACCGCGCCGACCAGTTCTTCCACGAGTGCATTCTCGCCGCCAGCCACAATCAA
TTCATCGAACAAATGGTGCCGGCCCTCGGTGCGCTGCTCGCCGTGTCCTTCGAAGTCTCGGCGGCCGATCCCGACGAATT
GCGCCGCACACTGCCTATCCATAAAGACATGGCCGATGCCATCGCCGCCCGGGATGCCGCGCGGGGGGTGTGGGCCTGCA
TGACCCTGATCGACAATGCCAACCTGGCCATCAAGCGGTTCTACCCGCAGGTGATGGCCGACAAGAAAGCCAGCTGA

Upstream 100 bases:

>100_bases
AAACCGCAGTCTGTGAAAGCAGGCTGCGGTTTTTTGTCGTTGACTCTCAATCGTATGATGATTAGCGTAGGCACCCACAG
CGAATCGCTTCGGGGTGTCC

Downstream 100 bases:

>100_bases
CAAAAACAACAAAACAGGAGGTTGCATGACGTGGACTGCGGTGACAGAGCATCGGGCGCAACTGGGCGAGGGCCCGTTCT
GGGACGCACTGACCCAGGCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSSSFHASTVDWLGAWIAAGQVKPGQAIKVEADLGEQLGVSRTVIREAIKTLVAKGMLEVGPKVGTRVLPIKRWNLFDPQ
VVGWLSRSGLPENFVDDLLDLRRTIEPMAVRWACERATVEQVQAVRQAYNALERAVDSGIDYNRADQFFHECILAASHNQ
FIEQMVPALGALLAVSFEVSAADPDELRRTLPIHKDMADAIAARDAARGVWACMTLIDNANLAIKRFYPQVMADKKAS

Sequences:

>Translated_238_residues
MSSSFHASTVDWLGAWIAAGQVKPGQAIKVEADLGEQLGVSRTVIREAIKTLVAKGMLEVGPKVGTRVLPIKRWNLFDPQ
VVGWLSRSGLPENFVDDLLDLRRTIEPMAVRWACERATVEQVQAVRQAYNALERAVDSGIDYNRADQFFHECILAASHNQ
FIEQMVPALGALLAVSFEVSAADPDELRRTLPIHKDMADAIAARDAARGVWACMTLIDNANLAIKRFYPQVMADKKAS
>Mature_237_residues
SSSFHASTVDWLGAWIAAGQVKPGQAIKVEADLGEQLGVSRTVIREAIKTLVAKGMLEVGPKVGTRVLPIKRWNLFDPQV
VGWLSRSGLPENFVDDLLDLRRTIEPMAVRWACERATVEQVQAVRQAYNALERAVDSGIDYNRADQFFHECILAASHNQF
IEQMVPALGALLAVSFEVSAADPDELRRTLPIHKDMADAIAARDAARGVWACMTLIDNANLAIKRFYPQVMADKKAS

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=30.3738317757009, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994961, Length=204, Percent_Identity=32.3529411764706, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786303, Length=174, Percent_Identity=31.0344827586207, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26255; Mature: 26124

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSFHASTVDWLGAWIAAGQVKPGQAIKVEADLGEQLGVSRTVIREAIKTLVAKGMLEV
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHH
GPKVGTRVLPIKRWNLFDPQVVGWLSRSGLPENFVDDLLDLRRTIEPMAVRWACERATVE
CHHCCCEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQAVRQAYNALERAVDSGIDYNRADQFFHECILAASHNQFIEQMVPALGALLAVSFEVS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AADPDELRRTLPIHKDMADAIAARDAARGVWACMTLIDNANLAIKRFYPQVMADKKAS
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSSFHASTVDWLGAWIAAGQVKPGQAIKVEADLGEQLGVSRTVIREAIKTLVAKGMLEV
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHH
GPKVGTRVLPIKRWNLFDPQVVGWLSRSGLPENFVDDLLDLRRTIEPMAVRWACERATVE
CHHCCCEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQAVRQAYNALERAVDSGIDYNRADQFFHECILAASHNQFIEQMVPALGALLAVSFEVS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AADPDELRRTLPIHKDMADAIAARDAARGVWACMTLIDNANLAIKRFYPQVMADKKAS
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]