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The map label for this gene is caiD [C]

Identifier: 77460209

GI number: 77460209

Start: 4517891

End: 4518682

Strand: Direct

Name: caiD [C]

Synonym: Pfl01_3988

Alternate gene names: 77460209

Gene position: 4517891-4518682 (Clockwise)

Preceding gene: 77460207

Following gene: 77460211

Centisome position: 70.17

GC content: 63.89

Gene sequence:

>792_bases
ATGAATCAGCCCTGCCCCGGCCGCGTGAGCCGTGCGCGCCACGGTCATGTGCATTTGATCGGTCTGGACCGCGCTGCCAA
GCGCAACGCCTTCGACCTAGACCTGCTCAACGACCTGGCCCTGGCCTATGGCGAATTCGAGGCCGACAGTAACGCACGGG
TGGCGGTGGTGTTCGGGCACGGCGAGCATTTCACCGCGGGGCTCGATCTGGTCAACGCCAGTTCTGCCCTCGCCCAAGGC
TGGCAGGTGCCGCCCGGCGGTTGCGATCCGTGGGGCGTTTTCGTCGGACCACGGGTCAGCAAACCGGTGATCGTCGCTGC
GCAGGGTTACTGCCTGACCATCGGCATCGAGTTGATGCTCGCCGCCGACATCAACCTGTGTGCCAGCAACACCCGCTTCG
CCCAGATGGAAGTGCAGCGTGGAATCTTTCCGTTTGGTGGTGCGACGTTGCGTTTCCATCAGATTGCCGGCTGGGGCAAT
GCCATGCGCTGGTTGCTGACCGGTGATGAATTCGATGCCCATGATGCGTTACGTCTGGGTCTGGTGCAGGAAGTCATGGC
CAGCGAGGATCTGCTGCCGCGCGCCATCGAACTGGCCGAACGCATCGCCCGGCAGGCGCCGTTGGGCGTGCAGGCAACGC
TGATGTCGGCGCGTCAGGCGCGCTATGAAGGTGAGACTGCGGCGGCTAAAAGCTTGCCGCCGCTGGTGAAGAAGTTGCTG
GCCACCGAAGATGCCAAGGAAGGCGTGCGCTCGCTGGTGGAGCGCACGCCCGGCGTTTTCAAAGGCCTTTGA

Upstream 100 bases:

>100_bases
TTTTCAAAGGGCCCGGCCCTGCGGGCGATGGCGCTTAAACGATTCACCGACGTGCGGCATCTGGTCGCTGCACCCTTTCT
TCCCCTGCGAGGAAACACCC

Downstream 100 bases:

>100_bases
AGATCAGGTCGCCGGACGTATGCAGTTGATCAACGTCTGCAACGAGTAGCCCAGCTTAGGCGCCAGCGCTTCAGCCCGGG
CGGTCAGCGCCTGCATGTCC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNQPCPGRVSRARHGHVHLIGLDRAAKRNAFDLDLLNDLALAYGEFEADSNARVAVVFGHGEHFTAGLDLVNASSALAQG
WQVPPGGCDPWGVFVGPRVSKPVIVAAQGYCLTIGIELMLAADINLCASNTRFAQMEVQRGIFPFGGATLRFHQIAGWGN
AMRWLLTGDEFDAHDALRLGLVQEVMASEDLLPRAIELAERIARQAPLGVQATLMSARQARYEGETAAAKSLPPLVKKLL
ATEDAKEGVRSLVERTPGVFKGL

Sequences:

>Translated_263_residues
MNQPCPGRVSRARHGHVHLIGLDRAAKRNAFDLDLLNDLALAYGEFEADSNARVAVVFGHGEHFTAGLDLVNASSALAQG
WQVPPGGCDPWGVFVGPRVSKPVIVAAQGYCLTIGIELMLAADINLCASNTRFAQMEVQRGIFPFGGATLRFHQIAGWGN
AMRWLLTGDEFDAHDALRLGLVQEVMASEDLLPRAIELAERIARQAPLGVQATLMSARQARYEGETAAAKSLPPLVKKLL
ATEDAKEGVRSLVERTPGVFKGL
>Mature_263_residues
MNQPCPGRVSRARHGHVHLIGLDRAAKRNAFDLDLLNDLALAYGEFEADSNARVAVVFGHGEHFTAGLDLVNASSALAQG
WQVPPGGCDPWGVFVGPRVSKPVIVAAQGYCLTIGIELMLAADINLCASNTRFAQMEVQRGIFPFGGATLRFHQIAGWGN
AMRWLLTGDEFDAHDALRLGLVQEVMASEDLLPRAIELAERIARQAPLGVQATLMSARQARYEGETAAAKSLPPLVKKLL
ATEDAKEGVRSLVERTPGVFKGL

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI70995211, Length=264, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=33.976833976834, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=32.6771653543307, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788682, Length=101, Percent_Identity=39.6039603960396, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=26.1538461538462, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=239, Percent_Identity=30.1255230125523, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=29.6, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=241, Percent_Identity=30.2904564315353, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=221, Percent_Identity=28.5067873303167, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=196, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653477, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24650670, Length=224, Percent_Identity=30.8035714285714, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=28.5024154589372, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=26.7175572519084, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920382, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28317; Mature: 28317

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPCPGRVSRARHGHVHLIGLDRAAKRNAFDLDLLNDLALAYGEFEADSNARVAVVFGH
CCCCCCCCHHHCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GEHFTAGLDLVNASSALAQGWQVPPGGCDPWGVFVGPRVSKPVIVAAQGYCLTIGIELML
CCEEECCHHHHCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEECCEEEEEEEEEEE
AADINLCASNTRFAQMEVQRGIFPFGGATLRFHQIAGWGNAMRWLLTGDEFDAHDALRLG
EECCCEECCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHH
LVQEVMASEDLLPRAIELAERIARQAPLGVQATLMSARQARYEGETAAAKSLPPLVKKLL
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHH
ATEDAKEGVRSLVERTPGVFKGL
HCCCHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MNQPCPGRVSRARHGHVHLIGLDRAAKRNAFDLDLLNDLALAYGEFEADSNARVAVVFGH
CCCCCCCCHHHCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GEHFTAGLDLVNASSALAQGWQVPPGGCDPWGVFVGPRVSKPVIVAAQGYCLTIGIELML
CCEEECCHHHHCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEECCEEEEEEEEEEE
AADINLCASNTRFAQMEVQRGIFPFGGATLRFHQIAGWGNAMRWLLTGDEFDAHDALRLG
EECCCEECCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHH
LVQEVMASEDLLPRAIELAERIARQAPLGVQATLMSARQARYEGETAAAKSLPPLVKKLL
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHH
ATEDAKEGVRSLVERTPGVFKGL
HCCCHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA