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The map label for this gene is yfbQ [H]

Identifier: 77460204

GI number: 77460204

Start: 4511731

End: 4512942

Strand: Direct

Name: yfbQ [H]

Synonym: Pfl01_3983

Alternate gene names: 77460204

Gene position: 4511731-4512942 (Clockwise)

Preceding gene: 77460200

Following gene: 77460205

Centisome position: 70.08

GC content: 60.89

Gene sequence:

>1212_bases
ATGCAGTTCAGCAAATCGAACAAGCTCGCCAACGTCTGCTACGACATTCGCGGCCCGGTGCTCAAGCACGCCAAACGCCT
GGAAGAGGAAGGCCATCGCATCCTCAAGCTGAACATCGGCAACCCGGCACCCTTTGGTTTCGAAGCGCCAGACGAAATTC
TCCAGGATGTGATCCGCAACCTGCCGACCGCCCAGGGCTACAGCGATTCCAAAGGCCTGTTCAGCGCGCGCAAGGCGGTG
ATGCAGTACTACCAGCAGAAGCAGGTCGAAGGTGTCGGCATCGAAGACATCTATCTGGGCAACGGCGTGTCCGAGCTGAT
CGTGATGTCGCTGCAGGCACTGCTCAACAACGGTGACGAAGTGCTGGTGCCGGCGCCAGACTACCCGCTGTGGACCGCAG
CCGTGAGCCTGGCCGGCGGTAACGCTGTGCATTACCTGTGCGACGAGGGCGCCGACTGGTTCCCGGACCTGGCCGACATC
AAGGCCAAGATCACCCCGAACACCAAGGCGATGGTGATCATCAACCCGAACAACCCGACCGGCGCGGTGTATTCGAAGGA
AGTGCTGTTGGGCATGCTCGAACTGGCTCGCCAGCACAATCTGGTGGTGTTCTCCGACGAAATCTACGACAAGATTCTTT
ACGACGACGCCGTGCACATCTGCACCGCTTCGCTGGCCCCGGACCTGCTGTGCCTGACCTTCAACGGCCTGTCCAAGTCG
TATCGCGTGGCGGGTTTCCGTTCCGGCTGGATCGCCATTTCCGGGCCGAAACACAACGCTCACAGCTACATCGAAGGCAT
CGACATGCTGGCCAACATGCGCCTGTGCGCCAACGTGCCGAGTCAGCATGCGATCCAGACCGCCCTGGGTGGCTATCAGA
GCATCAACGATCTGGTACTGCCGCAAGGTCGCCTGCTGGAACAGCGCAACCGCACCTGGGAGCTGCTCAACGACATTCCC
GGCGTTAGCTGCGTGAAGCCGATGGGCGCACTGTACGCGTTCCCGAAGATCGACCCGAAAGTCTGCCCGATCCACAACGA
CGAGAAATTCGTGCTCGACCTGCTGCTCTCCGAGAAGCTGCTGGTGGTGCAGGGCACGGCGTTCAACTGGCCGTGGCCTG
ACCACTTCCGCGTGGTCACCCTGCCGCGGGTCGATGACCTGGACATGGCCATCGGTCGCATCGGCAACTTCCTCAAGTCC
TACCGCCAGTAA

Upstream 100 bases:

>100_bases
GAAACCGCCGCTCGAGACACTTGCCTGTGTGAAGACGCAGGATTCCCAGCACGGTTGTCCACCCGCCGCCTGGATCGTTC
ATTTTCGGGATCACATCGCC

Downstream 100 bases:

>100_bases
CCGGCGCTCAGTGCGCAACGGCCCGAACGTTGCGCACTGTCTGATTCAGCAACACTTCTGCTGCGCCCCTACTCCAGCAC
CTTCTACACTTGCGACTCAT

Product: aminotransferase AlaT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MQFSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPDEILQDVIRNLPTAQGYSDSKGLFSARKAV
MQYYQQKQVEGVGIEDIYLGNGVSELIVMSLQALLNNGDEVLVPAPDYPLWTAAVSLAGGNAVHYLCDEGADWFPDLADI
KAKITPNTKAMVIINPNNPTGAVYSKEVLLGMLELARQHNLVVFSDEIYDKILYDDAVHICTASLAPDLLCLTFNGLSKS
YRVAGFRSGWIAISGPKHNAHSYIEGIDMLANMRLCANVPSQHAIQTALGGYQSINDLVLPQGRLLEQRNRTWELLNDIP
GVSCVKPMGALYAFPKIDPKVCPIHNDEKFVLDLLLSEKLLVVQGTAFNWPWPDHFRVVTLPRVDDLDMAIGRIGNFLKS
YRQ

Sequences:

>Translated_403_residues
MQFSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPDEILQDVIRNLPTAQGYSDSKGLFSARKAV
MQYYQQKQVEGVGIEDIYLGNGVSELIVMSLQALLNNGDEVLVPAPDYPLWTAAVSLAGGNAVHYLCDEGADWFPDLADI
KAKITPNTKAMVIINPNNPTGAVYSKEVLLGMLELARQHNLVVFSDEIYDKILYDDAVHICTASLAPDLLCLTFNGLSKS
YRVAGFRSGWIAISGPKHNAHSYIEGIDMLANMRLCANVPSQHAIQTALGGYQSINDLVLPQGRLLEQRNRTWELLNDIP
GVSCVKPMGALYAFPKIDPKVCPIHNDEKFVLDLLLSEKLLVVQGTAFNWPWPDHFRVVTLPRVDDLDMAIGRIGNFLKS
YRQ
>Mature_403_residues
MQFSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPDEILQDVIRNLPTAQGYSDSKGLFSARKAV
MQYYQQKQVEGVGIEDIYLGNGVSELIVMSLQALLNNGDEVLVPAPDYPLWTAAVSLAGGNAVHYLCDEGADWFPDLADI
KAKITPNTKAMVIINPNNPTGAVYSKEVLLGMLELARQHNLVVFSDEIYDKILYDDAVHICTASLAPDLLCLTFNGLSKS
YRVAGFRSGWIAISGPKHNAHSYIEGIDMLANMRLCANVPSQHAIQTALGGYQSINDLVLPQGRLLEQRNRTWELLNDIP
GVSCVKPMGALYAFPKIDPKVCPIHNDEKFVLDLLLSEKLLVVQGTAFNWPWPDHFRVVTLPRVDDLDMAIGRIGNFLKS
YRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=28.9124668435013, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI19263340, Length=477, Percent_Identity=26.4150943396226, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI215599424, Length=378, Percent_Identity=28.042328042328, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=24.7767857142857, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI95147551, Length=243, Percent_Identity=27.5720164609054, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI169881279, Length=243, Percent_Identity=27.5720164609054, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713254, Length=330, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI56713256, Length=330, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI169881281, Length=150, Percent_Identity=32, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=73.8154613466334, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=26.2254901960784, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786816, Length=268, Percent_Identity=23.134328358209, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787909, Length=219, Percent_Identity=23.7442922374429, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=29.9465240641711, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=466, Percent_Identity=24.6781115879828, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=184, Percent_Identity=33.695652173913, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=184, Percent_Identity=33.695652173913, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=234, Percent_Identity=28.6324786324786, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=359, Percent_Identity=27.8551532033426, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=27.0422535211268, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=282, Percent_Identity=26.9503546099291, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=26.2032085561497, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24641770, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641760, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641768, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641766, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641764, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI45551451, Length=470, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28573069, Length=167, Percent_Identity=28.7425149700599, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646114, Length=167, Percent_Identity=28.7425149700599, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573067, Length=167, Percent_Identity=28.7425149700599, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573065, Length=167, Percent_Identity=28.7425149700599, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44686; Mature: 44686

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPDEILQDVIRN
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LPTAQGYSDSKGLFSARKAVMQYYQQKQVEGVGIEDIYLGNGVSELIVMSLQALLNNGDE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VLVPAPDYPLWTAAVSLAGGNAVHYLCDEGADWFPDLADIKAKITPNTKAMVIINPNNPT
EEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECCCCCC
GAVYSKEVLLGMLELARQHNLVVFSDEIYDKILYDDAVHICTASLAPDLLCLTFNGLSKS
CCHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
YRVAGFRSGWIAISGPKHNAHSYIEGIDMLANMRLCANVPSQHAIQTALGGYQSINDLVL
EEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCHHHHHHHCC
PQGRLLEQRNRTWELLNDIPGVSCVKPMGALYAFPKIDPKVCPIHNDEKFVLDLLLSEKL
CCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCE
LVVQGTAFNWPWPDHFRVVTLPRVDDLDMAIGRIGNFLKSYRQ
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFSKSNKLANVCYDIRGPVLKHAKRLEEEGHRILKLNIGNPAPFGFEAPDEILQDVIRN
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LPTAQGYSDSKGLFSARKAVMQYYQQKQVEGVGIEDIYLGNGVSELIVMSLQALLNNGDE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VLVPAPDYPLWTAAVSLAGGNAVHYLCDEGADWFPDLADIKAKITPNTKAMVIINPNNPT
EEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCEEEECCCCEEEEEECCCCCC
GAVYSKEVLLGMLELARQHNLVVFSDEIYDKILYDDAVHICTASLAPDLLCLTFNGLSKS
CCHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
YRVAGFRSGWIAISGPKHNAHSYIEGIDMLANMRLCANVPSQHAIQTALGGYQSINDLVL
EEEEEECCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCHHHHHHHCC
PQGRLLEQRNRTWELLNDIPGVSCVKPMGALYAFPKIDPKVCPIHNDEKFVLDLLLSEKL
CCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCE
LVVQGTAFNWPWPDHFRVVTLPRVDDLDMAIGRIGNFLKSYRQ
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]