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The map label for this gene is htpX [H]

Identifier: 77460205

GI number: 77460205

Start: 4513247

End: 4514134

Strand: Direct

Name: htpX [H]

Synonym: Pfl01_3984

Alternate gene names: 77460205

Gene position: 4513247-4514134 (Clockwise)

Preceding gene: 77460204

Following gene: 77460207

Centisome position: 70.1

GC content: 60.02

Gene sequence:

>888_bases
ATGATGCGCATCCTGCTGTTTTTGGCCACTAACCTGGCGGTCGTGCTGATAGCCAGCATCACCCTGAGCCTTTTTGGCTT
CAACGGGTTCATGGCGGCCAACGGGGTTGATCTCAACCTCAGTCAGCTGCTGGTTTTCTGTGCAGTCTTTGGTTTTGCCG
GTTCCCTGTTCTCGCTGTTCATCTCCAAGTGGATGGCGAAGATGAGCACCGGCACCCAGATCATCACCCAGCCACGCACT
CGTCACGAGCAATGGCTGCTGCAAACCGTCGAGCAACTGTCCCGGGAAGCCGGAATCAAGATGCCCGAAGTCGGGATTTT
CCCGGCCTACGAAGCGAACGCCTTCGCTACCGGCTGGAACAAGAACGACGCACTGGTTGCGGTCAGCCAGGGCTTGCTCG
AACGCTTCAAGGAAGACGAAGTGCGGGCCGTGCTGGCTCACGAGATCGGTCACGTGGCCAATGGCGACATGGTTACCCTG
GCACTGATCCAGGGCGTGGTGAACACCTTCGTGATGTTCTTCGCGCGGATCATCGGCAACTTCGTCGACAAGGTGATCTT
CAAGAACGAAGAAGGCCAGGGCATGGCCTACTACATCGCGACCATCTTCGCCGAACTGGTACTGGGCATTCTGGCCAGCG
CGATCGTGATGTGGTTCTCGCGCAAGCGCGAGTTCCGTGCCGACGATGCCGGTGCCCGCCTGGCCGGTACCGGCGCGATG
ATCAACGCATTGCAACGCCTGCGCGCCGAACAGGGCCTGCCGGTGCACATGCCGGACACCCTGAACGCCTTCGGCATCAA
CGGTGGCATCAAACAAGGGTTCGCCCGCATGTTCATGAGCCACCCGCCGCTGGAAGAGCGTATCGACGCCCTGCGTCGTC
GCGGTTGA

Upstream 100 bases:

>100_bases
GGACACAGTTTGAAATAGTCACTCGGTTGAATCGCCAGGTGCCGCACCTTATATACCCCGCAGTACGCTACATCTTTAGC
TTGAGGAGACTTCTACAACC

Downstream 100 bases:

>100_bases
TCAAACCGGCGCACCAATGAAAAGGCCCGCAGTGATGCGGGCCTTTTTTTGCCTGTCGTTTACACCCCGCGAATCCGGTA
AACCCGTTCCTCAAGCCGGG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLSQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIITQPRT
RHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFKEDEVRAVLAHEIGHVANGDMVTL
ALIQGVVNTFVMFFARIIGNFVDKVIFKNEEGQGMAYYIATIFAELVLGILASAIVMWFSRKREFRADDAGARLAGTGAM
INALQRLRAEQGLPVHMPDTLNAFGINGGIKQGFARMFMSHPPLEERIDALRRRG

Sequences:

>Translated_295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLSQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIITQPRT
RHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFKEDEVRAVLAHEIGHVANGDMVTL
ALIQGVVNTFVMFFARIIGNFVDKVIFKNEEGQGMAYYIATIFAELVLGILASAIVMWFSRKREFRADDAGARLAGTGAM
INALQRLRAEQGLPVHMPDTLNAFGINGGIKQGFARMFMSHPPLEERIDALRRRG
>Mature_295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLSQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIITQPRT
RHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFKEDEVRAVLAHEIGHVANGDMVTL
ALIQGVVNTFVMFFARIIGNFVDKVIFKNEEGQGMAYYIATIFAELVLGILASAIVMWFSRKREFRADDAGARLAGTGAM
INALQRLRAEQGLPVHMPDTLNAFGINGGIKQGFARMFMSHPPLEERIDALRRRG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=298, Percent_Identity=46.9798657718121, Blast_Score=256, Evalue=9e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32555; Mature: 32555

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLSQLLVFCAVFGFAGSLFSLF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISKWMAKMSTGTQIITQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWN
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSQGLLERFKEDEVRAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIIGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDKVIFKNEEGQGMAYYIATIFAELVLGILASAIVMWFSRKREFRADDAGARLAGTGAM
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHH
INALQRLRAEQGLPVHMPDTLNAFGINGGIKQGFARMFMSHPPLEERIDALRRRG
HHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLSQLLVFCAVFGFAGSLFSLF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISKWMAKMSTGTQIITQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWN
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSQGLLERFKEDEVRAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIIGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDKVIFKNEEGQGMAYYIATIFAELVLGILASAIVMWFSRKREFRADDAGARLAGTGAM
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHH
INALQRLRAEQGLPVHMPDTLNAFGINGGIKQGFARMFMSHPPLEERIDALRRRG
HHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA