Click here to switch to the map view.

The map label for this gene is msrB

Identifier: 77460203

GI number: 77460203

Start: 4511110

End: 4511505

Strand: Reverse

Name: msrB

Synonym: Pfl01_3982

Alternate gene names: 77460203

Gene position: 4511505-4511110 (Counterclockwise)

Preceding gene: 77460206

Following gene: 77460202

Centisome position: 70.07

GC content: 61.36

Gene sequence:

>396_bases
ATGGAAAAGATTGAAAAGACCCTGGAAGAATGGCGGGCGATGCTCGACCCCGAGCAGTTCAACGTGTGCCGCCTGAGCGC
CACCGAGCGACCGTTCTCCGGCAAGTACAACGCCACCAAGACCGATGGCGTCTACCACTGCATCTGCTGCAACGAACCGC
TGTTCGACTCCAAGACCAAATTCGACTCCGGCTGCGGCTGGCCAAGCTTCTACGCGCCGATCGGCGACAACGCCATGACC
GAAATCCGTGACACCAGCCACGGCATGATTCGCACCGAAGTGAAATGCGCCAAGTGCGATGCGCACCTTGGCCACGTCTT
CCCTGACGGCCCGCCGCCGACCGGCCTGCGTTACTGCATCAACTCGGTGTGCCTGGACCTGGTGCCGCGCGAGTAA

Upstream 100 bases:

>100_bases
ACCCGCTGCCAGACTGGCGTGTGACGAGGCGCAATCATACGTGCCGCCCGATCCGTGGAAAAGGTACAGATCGGGCTTTT
TCAGCCGCTGAGGTGTGATG

Downstream 100 bases:

>100_bases
CCGATACGGGCGATCCACGGGTCGCCTTTCGAATAATTAAATTGCACGCAATTCAATTGCTCGCTATTTTTGCCGTCTAT
CCATTTTTCAAGAGTGCGCA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MEKIEKTLEEWRAMLDPEQFNVCRLSATERPFSGKYNATKTDGVYHCICCNEPLFDSKTKFDSGCGWPSFYAPIGDNAMT
EIRDTSHGMIRTEVKCAKCDAHLGHVFPDGPPPTGLRYCINSVCLDLVPRE

Sequences:

>Translated_131_residues
MEKIEKTLEEWRAMLDPEQFNVCRLSATERPFSGKYNATKTDGVYHCICCNEPLFDSKTKFDSGCGWPSFYAPIGDNAMT
EIRDTSHGMIRTEVKCAKCDAHLGHVFPDGPPPTGLRYCINSVCLDLVPRE
>Mature_131_residues
MEKIEKTLEEWRAMLDPEQFNVCRLSATERPFSGKYNATKTDGVYHCICCNEPLFDSKTKFDSGCGWPSFYAPIGDNAMT
EIRDTSHGMIRTEVKCAKCDAHLGHVFPDGPPPTGLRYCINSVCLDLVPRE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI117606353, Length=129, Percent_Identity=53.4883720930233, Blast_Score=139, Evalue=8e-34,
Organism=Homo sapiens, GI301336164, Length=129, Percent_Identity=48.8372093023256, Blast_Score=136, Evalue=5e-33,
Organism=Homo sapiens, GI301336162, Length=129, Percent_Identity=48.8372093023256, Blast_Score=136, Evalue=5e-33,
Organism=Homo sapiens, GI73089054, Length=129, Percent_Identity=48.8372093023256, Blast_Score=136, Evalue=5e-33,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=49.6062992125984, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788077, Length=125, Percent_Identity=54.4, Blast_Score=153, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553450, Length=124, Percent_Identity=50.8064516129032, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=124, Percent_Identity=50.8064516129032, Blast_Score=129, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=124, Percent_Identity=45.9677419354839, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=51.5625, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=48.8888888888889, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=51.5625, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=51.5625, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=51.5625, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=47.4820143884892, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=47.4820143884892, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_PSEPF (Q3K935)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_349710.1
- ProteinModelPortal:   Q3K935
- SMR:   Q3K935
- STRING:   Q3K935
- GeneID:   3714008
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_3982
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- ProtClustDB:   PRK00222
- BioCyc:   PFLU205922:PFL_3982-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 14753; Mature: 14753

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
9.9 %Cys+Met (Translated Protein)
6.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
9.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIEKTLEEWRAMLDPEQFNVCRLSATERPFSGKYNATKTDGVYHCICCNEPLFDSKTK
CHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
FDSGCGWPSFYAPIGDNAMTEIRDTSHGMIRTEVKCAKCDAHLGHVFPDGPPPTGLRYCI
CCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHH
NSVCLDLVPRE
HHHHHHHCCCC
>Mature Secondary Structure
MEKIEKTLEEWRAMLDPEQFNVCRLSATERPFSGKYNATKTDGVYHCICCNEPLFDSKTK
CHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
FDSGCGWPSFYAPIGDNAMTEIRDTSHGMIRTEVKCAKCDAHLGHVFPDGPPPTGLRYCI
CCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHH
NSVCLDLVPRE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA