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The map label for this gene is dsbG [H]

Identifier: 77460159

GI number: 77460159

Start: 4452632

End: 4453381

Strand: Direct

Name: dsbG [H]

Synonym: Pfl01_3938

Alternate gene names: 77460159

Gene position: 4452632-4453381 (Clockwise)

Preceding gene: 77460158

Following gene: 77460162

Centisome position: 69.16

GC content: 62.27

Gene sequence:

>750_bases
CTGACGCTGACCCTGGGCGCCGCCCTGCTGCACTTGCCGTCGGTCCAGGCCGCTGAAGAACTGCCTGAAGCGATCAAGAA
GATCGAAGCCAAGGGCGCCAAGATCGTCGGCCAGTTCGACGCGCCGGACGGCTTGCGCGGTTACGCCGCGCAATACCAGA
ACCGCGGCATGGCGCTGTACCTGACGCCGGACGGCAAGCACGTGCTGCTGGGCAACCTGTACGACGCCGACGGCAACGAC
CTGAGCAGCGCACCGCTGCAAAAACTGGTATACGCGCCGATGGCCAAGGAAGTCTGGGCCAAGTTCGAGGCCAGCAACTG
GATTCAGGACGGCAACAAGGATGCACCACGCACTGTGTACCTGTTCAGCGACCCGAACTGCCCGTATTGCAACATGTTCT
GGGAACAGGCCCGTCCCTGGGTCAAGGCCGGCAAGGTGCAGTTGCGACACATCATGGTCGGCATCATCCGCGAAGACAGC
CCGGCCAAAGCCGCTGCCCTGCTCGCCGCCAAGGACCCGAGCAAAGCCCTGGAAGATCACGAGAAGGCCGGCAAGGCCAG
CACCCTCAAGGCCTTGAAGGACATTCCGGTCGCCGTGCAGACCAAACTCGCGGCGAACATGCAGTTGATGGAAGACCTGG
AGTTACAGGCCACCCCGGCGATCTTCTACATGGACGACAAGGGCGAACTGCAACAACAGCAAGGTGCACCGACGCCGGAC
AAGCTGGCGAAGATTCTCGGCCCGAAATAA

Upstream 100 bases:

>100_bases
GCCTGGCCCGTGCCCTGGAAAGCTTCGACACCCCGGCCTCCAGCCCGAATCCGGCCACCTCTTCTTCAAGGAAACTGCCA
TGCCCCGCCTCCGCCACCTG

Downstream 100 bases:

>100_bases
AAAACGCCCACGCAATGCGTGGGCGTTTTCGTTACTTCAGCCCAGCCAGAAACTTCAGCAGCGTGTCGGTCACGAAGGTT
GGATTCTCCAGATTGGAGAT

Product: disulfide isomerase/thiol-disulfide oxidase

Products: protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTLTLGAALLHLPSVQAAEELPEAIKKIEAKGAKIVGQFDAPDGLRGYAAQYQNRGMALYLTPDGKHVLLGNLYDADGND
LSSAPLQKLVYAPMAKEVWAKFEASNWIQDGNKDAPRTVYLFSDPNCPYCNMFWEQARPWVKAGKVQLRHIMVGIIREDS
PAKAAALLAAKDPSKALEDHEKAGKASTLKALKDIPVAVQTKLAANMQLMEDLELQATPAIFYMDDKGELQQQQGAPTPD
KLAKILGPK

Sequences:

>Translated_249_residues
MTLTLGAALLHLPSVQAAEELPEAIKKIEAKGAKIVGQFDAPDGLRGYAAQYQNRGMALYLTPDGKHVLLGNLYDADGND
LSSAPLQKLVYAPMAKEVWAKFEASNWIQDGNKDAPRTVYLFSDPNCPYCNMFWEQARPWVKAGKVQLRHIMVGIIREDS
PAKAAALLAAKDPSKALEDHEKAGKASTLKALKDIPVAVQTKLAANMQLMEDLELQATPAIFYMDDKGELQQQQGAPTPD
KLAKILGPK
>Mature_248_residues
TLTLGAALLHLPSVQAAEELPEAIKKIEAKGAKIVGQFDAPDGLRGYAAQYQNRGMALYLTPDGKHVLLGNLYDADGNDL
SSAPLQKLVYAPMAKEVWAKFEASNWIQDGNKDAPRTVYLFSDPNCPYCNMFWEQARPWVKAGKVQLRHIMVGIIREDSP
AKAAALLAAKDPSKALEDHEKAGKASTLKALKDIPVAVQTKLAANMQLMEDLELQATPAIFYMDDKGELQQQQGAPTPDK
LAKILGPK

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=232, Percent_Identity=47.4137931034483, Blast_Score=239, Evalue=9e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27167; Mature: 27035

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTLGAALLHLPSVQAAEELPEAIKKIEAKGAKIVGQFDAPDGLRGYAAQYQNRGMALY
CEEEHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEEE
LTPDGKHVLLGNLYDADGNDLSSAPLQKLVYAPMAKEVWAKFEASNWIQDGNKDAPRTVY
ECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LFSDPNCPYCNMFWEQARPWVKAGKVQLRHIMVGIIREDSPAKAAALLAAKDPSKALEDH
EEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCCHHHHHHH
EKAGKASTLKALKDIPVAVQTKLAANMQLMEDLELQATPAIFYMDDKGELQQQQGAPTPD
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCHH
KLAKILGPK
HHHHHHCCC
>Mature Secondary Structure 
TLTLGAALLHLPSVQAAEELPEAIKKIEAKGAKIVGQFDAPDGLRGYAAQYQNRGMALY
EEEHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCEEEE
LTPDGKHVLLGNLYDADGNDLSSAPLQKLVYAPMAKEVWAKFEASNWIQDGNKDAPRTVY
ECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LFSDPNCPYCNMFWEQARPWVKAGKVQLRHIMVGIIREDSPAKAAALLAAKDPSKALEDH
EEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCCHHHHHHH
EKAGKASTLKALKDIPVAVQTKLAANMQLMEDLELQATPAIFYMDDKGELQQQQGAPTPD
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCHH
KLAKILGPK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein with reduced SH groups [C]

Specific reaction: protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]