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The map label for this gene is qseC [H]

Identifier: 77460155

GI number: 77460155

Start: 4447874

End: 4449199

Strand: Reverse

Name: qseC [H]

Synonym: Pfl01_3934

Alternate gene names: 77460155

Gene position: 4449199-4447874 (Counterclockwise)

Preceding gene: 77460156

Following gene: 77460154

Centisome position: 69.1

GC content: 65.46

Gene sequence:

>1326_bases
GTGATGAGCCTGCGCCTGCGCCTGAGCCTGACCCTCGGCGCCGCATTCGCGCTGATCTGGGCATTGGCGGCCGCCTGGAT
GCTCAGCGACCTGCGCAACCAGATGATGTTTTCCCTCGACCAGCGCCTGGTGGCGTCGGCGCGGATGGTCGCCGGGTTGC
TGGAACAATTGCCGGCTGTCCCGAGCAAAGGCGAGGGCACTCATTTCAGCGCCGAGCAGTTGAACATTCCCGGCGGCATG
GCCTGTCAGGTCAGCTCGCTGCGCGGGGAAATCCTCGCTCGCAGCCACAACAATCCGGAACAGGCGCTGGAAGCCCAGAA
GATGGGCTTCCACGATCAAATGATCGACGGTGCCCCATGGCGCAGCTTCACCCTGGCCCGGGGCGATGTGCGTATTACCA
CCGCCGACCGGGTGATCGAGCGCGAAGCCCTGAACATGTCGATCCTGCTGGCGGCCTCGGTGCCGGTCGGCGTGGCGCTG
CTTGGCTGCCTGTGCCTGTTGTGGCTGGGGATCGGCCAGGGGTTGGCGCCGCTCAACCGCTTGCGTGAAGCCTTGATGCG
TCGCAACGCGGATTCGCTTGAGCCGTTGCAGTTGCAGTCATTCCCCAGCGAACTGAAACCGCTGCTGGAAACCCAGAACC
AATTGTTTCAGCGCATCGGCAAGACCATCGAGCGCGAGCGTCGCCTGACCGGCGATGCCGCCCACGAACTGCGCAGCCCG
CTGACGGCGATCAAGACCCACCTGCAAGTGGCGCGCATGACCGATGGCAGCGCCCGCGATCAGTCTCTGGCCCGAGCCGA
GGAGGGTGCCGACCGCCTGCATCGGACCCTTGAGCAGTTACTGTTGCTGGCGCGGGTCGAAGGCAGTCTGTCGTTCGACG
ACGGTGTGCAGTGCAGCGCCGAGCAGGTAGCGAAACTGGCGATTCAGGACTCGGCCAGCGACCAGCGTCAGCGCATCAGG
CTGCATCTGCCTGAACACTTGTCCGCTGCGCCGCTGCAAATGCCGGCGGTGCTGTCGATCGCGGCCCTGCGCAACCTGTT
GGACAACGCTCTGCGTCACACGCCGACGGACGGCGCGGTGGACCTGAGCCTGGAAACCAGCGCCAATCGCGTCCGTTTTG
TGGTGCGCGACCATGGGCCGGGAATCGCCCCTGACGATCTGCAACACCTGACCCAGCGCTTCTGGCGCAACGGCCAGAGC
ACCGGCTGCGGACTGGGGCTGGCGATTGTCCAGGCGATCGTTCAGCGCTGCGCCTGCACCCTGCATTTCGACAGCCGTCC
GGATGGTTTGCGGGTCGAGCTGACCATGCCGCTGCAACCGGTCTGA

Upstream 100 bases:

>100_bases
ACATCCATCACCTGCGCAGCAAACTCGGCAAAGGCATCGTCGAAACCGTGCGCGGTCTGGGTTATCGCCTGGGCCCGGCC
GATGGCGGAGAACCCGACAA

Downstream 100 bases:

>100_bases
CAGTTTGCCGGGCACATCAAATGTAACCTCTCTCCATTAGTCATCCGCCGGCCGTGACGGTATTGTCGCCCCAGCCTTTG
ACTCAATGGATTGAGGGAAA

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MMSLRLRLSLTLGAAFALIWALAAAWMLSDLRNQMMFSLDQRLVASARMVAGLLEQLPAVPSKGEGTHFSAEQLNIPGGM
ACQVSSLRGEILARSHNNPEQALEAQKMGFHDQMIDGAPWRSFTLARGDVRITTADRVIEREALNMSILLAASVPVGVAL
LGCLCLLWLGIGQGLAPLNRLREALMRRNADSLEPLQLQSFPSELKPLLETQNQLFQRIGKTIERERRLTGDAAHELRSP
LTAIKTHLQVARMTDGSARDQSLARAEEGADRLHRTLEQLLLLARVEGSLSFDDGVQCSAEQVAKLAIQDSASDQRQRIR
LHLPEHLSAAPLQMPAVLSIAALRNLLDNALRHTPTDGAVDLSLETSANRVRFVVRDHGPGIAPDDLQHLTQRFWRNGQS
TGCGLGLAIVQAIVQRCACTLHFDSRPDGLRVELTMPLQPV

Sequences:

>Translated_441_residues
MMSLRLRLSLTLGAAFALIWALAAAWMLSDLRNQMMFSLDQRLVASARMVAGLLEQLPAVPSKGEGTHFSAEQLNIPGGM
ACQVSSLRGEILARSHNNPEQALEAQKMGFHDQMIDGAPWRSFTLARGDVRITTADRVIEREALNMSILLAASVPVGVAL
LGCLCLLWLGIGQGLAPLNRLREALMRRNADSLEPLQLQSFPSELKPLLETQNQLFQRIGKTIERERRLTGDAAHELRSP
LTAIKTHLQVARMTDGSARDQSLARAEEGADRLHRTLEQLLLLARVEGSLSFDDGVQCSAEQVAKLAIQDSASDQRQRIR
LHLPEHLSAAPLQMPAVLSIAALRNLLDNALRHTPTDGAVDLSLETSANRVRFVVRDHGPGIAPDDLQHLTQRFWRNGQS
TGCGLGLAIVQAIVQRCACTLHFDSRPDGLRVELTMPLQPV
>Mature_441_residues
MMSLRLRLSLTLGAAFALIWALAAAWMLSDLRNQMMFSLDQRLVASARMVAGLLEQLPAVPSKGEGTHFSAEQLNIPGGM
ACQVSSLRGEILARSHNNPEQALEAQKMGFHDQMIDGAPWRSFTLARGDVRITTADRVIEREALNMSILLAASVPVGVAL
LGCLCLLWLGIGQGLAPLNRLREALMRRNADSLEPLQLQSFPSELKPLLETQNQLFQRIGKTIERERRLTGDAAHELRSP
LTAIKTHLQVARMTDGSARDQSLARAEEGADRLHRTLEQLLLLARVEGSLSFDDGVQCSAEQVAKLAIQDSASDQRQRIR
LHLPEHLSAAPLQMPAVLSIAALRNLLDNALRHTPTDGAVDLSLETSANRVRFVVRDHGPGIAPDDLQHLTQRFWRNGQS
TGCGLGLAIVQAIVQRCACTLHFDSRPDGLRVELTMPLQPV

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=32.9621380846325, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=31.8181818181818, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786783, Length=337, Percent_Identity=26.7062314540059, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=27.0547945205479, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=33.4728033472803, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=27.3542600896861, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=25.4480286738351, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=282, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790861, Length=354, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48386; Mature: 48386

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLRLRLSLTLGAAFALIWALAAAWMLSDLRNQMMFSLDQRLVASARMVAGLLEQLPAV
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSKGEGTHFSAEQLNIPGGMACQVSSLRGEILARSHNNPEQALEAQKMGFHDQMIDGAPW
CCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCC
RSFTLARGDVRITTADRVIEREALNMSILLAASVPVGVALLGCLCLLWLGIGQGLAPLNR
CCEEEECCCEEEEHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHH
LREALMRRNADSLEPLQLQSFPSELKPLLETQNQLFQRIGKTIERERRLTGDAAHELRSP
HHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LTAIKTHLQVARMTDGSARDQSLARAEEGADRLHRTLEQLLLLARVEGSLSFDDGVQCSA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
EQVAKLAIQDSASDQRQRIRLHLPEHLSAAPLQMPAVLSIAALRNLLDNALRHTPTDGAV
HHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
DLSLETSANRVRFVVRDHGPGIAPDDLQHLTQRFWRNGQSTGCGLGLAIVQAIVQRCACT
EEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEE
LHFDSRPDGLRVELTMPLQPV
EEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MMSLRLRLSLTLGAAFALIWALAAAWMLSDLRNQMMFSLDQRLVASARMVAGLLEQLPAV
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSKGEGTHFSAEQLNIPGGMACQVSSLRGEILARSHNNPEQALEAQKMGFHDQMIDGAPW
CCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCC
RSFTLARGDVRITTADRVIEREALNMSILLAASVPVGVALLGCLCLLWLGIGQGLAPLNR
CCEEEECCCEEEEHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHH
LREALMRRNADSLEPLQLQSFPSELKPLLETQNQLFQRIGKTIERERRLTGDAAHELRSP
HHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LTAIKTHLQVARMTDGSARDQSLARAEEGADRLHRTLEQLLLLARVEGSLSFDDGVQCSA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
EQVAKLAIQDSASDQRQRIRLHLPEHLSAAPLQMPAVLSIAALRNLLDNALRHTPTDGAV
HHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCE
DLSLETSANRVRFVVRDHGPGIAPDDLQHLTQRFWRNGQSTGCGLGLAIVQAIVQRCACT
EEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEE
LHFDSRPDGLRVELTMPLQPV
EEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]