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The map label for this gene is qseB [H]

Identifier: 77460156

GI number: 77460156

Start: 4449196

End: 4449876

Strand: Reverse

Name: qseB [H]

Synonym: Pfl01_3935

Alternate gene names: 77460156

Gene position: 4449876-4449196 (Counterclockwise)

Preceding gene: 77460160

Following gene: 77460155

Centisome position: 69.11

GC content: 62.26

Gene sequence:

>681_bases
ATGCACGTACTGGTTTGCGAAGACGATGAGTTGATCGCCAGCGGGATCGTCGCCGGGCTGACGGCGCAAGGCCTGACGGT
CGAGCACGTCAACACGGCCTCCAAGGCGCGGGCGATTCTCAAGGTTGCCGAATTTGACGTGATGGTGCTCGATCTCGGGC
TGCCGGACGAAGATGGTCTCAAGTTGCTGCAACAACTGCGTCAGCAAGGCCTGGAGATTCCGGTGCTGATCCTGACTGCA
CGGGATTCGGTCACGGATCGGGTCGACGGCTTGCAATCCGGCGCCGACGACTACCTGCTCAAGCCGTTCGACCTGCGCGA
GTTGTTCGCCCGCCTGCAAACCCTGCTGCGCCGGGTGGCCGGACGCAGCGTCAATCTGATCGAACACGGCGCGCTGACTT
ACGATCCGAGCAGTCGCGAAACCACCCTGGCGGGGCGTCCGGTGGATCTGTCGCGGCGCGAGCAGTCGTTGTTGCAAGCC
TTGCTGCACAACCGTGGCCGGGTGCTGTCCACCGAGCAGTTGAAGGACAGCGTCTACGGTTTCAACGATGAACTGGAAAG
CAACGCGCTCAATGTGCACATCCATCACCTGCGCAGCAAACTCGGCAAAGGCATCGTCGAAACCGTGCGCGGTCTGGGTT
ATCGCCTGGGCCCGGCCGATGGCGGAGAACCCGACAAGTGA

Upstream 100 bases:

>100_bases
CCGATGATTAACCGCGACGCCCTTGTCGCGGTGGCGTTCGGGGCATAATGTCGGCTTAATCGGCCAGCGGCCTAATCAGC
ACTTTTCCACGGGACTCACC

Downstream 100 bases:

>100_bases
TGAGCCTGCGCCTGCGCCTGAGCCTGACCCTCGGCGCCGCATTCGCGCTGATCTGGGCATTGGCGGCCGCCTGGATGCTC
AGCGACCTGCGCAACCAGAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MHVLVCEDDELIASGIVAGLTAQGLTVEHVNTASKARAILKVAEFDVMVLDLGLPDEDGLKLLQQLRQQGLEIPVLILTA
RDSVTDRVDGLQSGADDYLLKPFDLRELFARLQTLLRRVAGRSVNLIEHGALTYDPSSRETTLAGRPVDLSRREQSLLQA
LLHNRGRVLSTEQLKDSVYGFNDELESNALNVHIHHLRSKLGKGIVETVRGLGYRLGPADGGEPDK

Sequences:

>Translated_226_residues
MHVLVCEDDELIASGIVAGLTAQGLTVEHVNTASKARAILKVAEFDVMVLDLGLPDEDGLKLLQQLRQQGLEIPVLILTA
RDSVTDRVDGLQSGADDYLLKPFDLRELFARLQTLLRRVAGRSVNLIEHGALTYDPSSRETTLAGRPVDLSRREQSLLQA
LLHNRGRVLSTEQLKDSVYGFNDELESNALNVHIHHLRSKLGKGIVETVRGLGYRLGPADGGEPDK
>Mature_226_residues
MHVLVCEDDELIASGIVAGLTAQGLTVEHVNTASKARAILKVAEFDVMVLDLGLPDEDGLKLLQQLRQQGLEIPVLILTA
RDSVTDRVDGLQSGADDYLLKPFDLRELFARLQTLLRRVAGRSVNLIEHGALTYDPSSRETTLAGRPVDLSRREQSLLQA
LLHNRGRVLSTEQLKDSVYGFNDELESNALNVHIHHLRSKLGKGIVETVRGLGYRLGPADGGEPDK

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=46.0829493087558, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=42.5925925925926, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=35.3211009174312, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.070796460177, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=35.1351351351351, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=38.6666666666667, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=33.0275229357798, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=35.7142857142857, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=33.4763948497854, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=31.25, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=31.0810810810811, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI2367329, Length=174, Percent_Identity=37.9310344827586, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=27.0386266094421, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=31.1320754716981, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24801; Mature: 24801

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLVCEDDELIASGIVAGLTAQGLTVEHVNTASKARAILKVAEFDVMVLDLGLPDEDGL
CEEEEECCCHHHHHHHHHHHHCCCEEEEHHCHHHHHHHHHHHHHHCEEEEECCCCCHHHH
KLLQQLRQQGLEIPVLILTARDSVTDRVDGLQSGADDYLLKPFDLRELFARLQTLLRRVA
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRSVNLIEHGALTYDPSSRETTLAGRPVDLSRREQSLLQALLHNRGRVLSTEQLKDSVYG
CCCCCEEECCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCC
FNDELESNALNVHIHHLRSKLGKGIVETVRGLGYRLGPADGGEPDK
CCCCCCCCHHEEHHHHHHHHHCHHHHHHHHHCCEECCCCCCCCCCC
>Mature Secondary Structure
MHVLVCEDDELIASGIVAGLTAQGLTVEHVNTASKARAILKVAEFDVMVLDLGLPDEDGL
CEEEEECCCHHHHHHHHHHHHCCCEEEEHHCHHHHHHHHHHHHHHCEEEEECCCCCHHHH
KLLQQLRQQGLEIPVLILTARDSVTDRVDGLQSGADDYLLKPFDLRELFARLQTLLRRVA
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRSVNLIEHGALTYDPSSRETTLAGRPVDLSRREQSLLQALLHNRGRVLSTEQLKDSVYG
CCCCCEEECCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCC
FNDELESNALNVHIHHLRSKLGKGIVETVRGLGYRLGPADGGEPDK
CCCCCCCCHHEEHHHHHHHHHCHHHHHHHHHCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]