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The map label for this gene is hlyB [H]

Identifier: 77459990

GI number: 77459990

Start: 4263024

End: 4264706

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_3768

Alternate gene names: 77459990

Gene position: 4264706-4263024 (Counterclockwise)

Preceding gene: 77459991

Following gene: 77459988

Centisome position: 66.24

GC content: 63.99

Gene sequence:

>1683_bases
ATGCGCCTGAGTCTCAAGGCTAAAGTCCTGTCCCTTGCCGTCCTTCCGGTTTTGCTCTTTGCGCTGGTGATCAGCCTGAC
CACGCTGTTCATCCTTCAGGAACAGGCGCGCAATGAAGTCCAGCAGACCCGCGAACGCCTGCTCGGTGACGCCAAAGCCA
CGCTGGCCAGTTACGTCGCCGTGGCCATGACCACCATCAAACCGTTGTACGACGCCGCCGCTCCCGGTGACGCCGATGCG
CGGGCGCAGGTGATCAAGCTGCTGTCGAGCATCAAGTACGGCAAGGACGGCTACTTCTTCGGCTACGACTCCGAGACCGT
GCGCCTGTTCAAGGCCAACGACCCCGAAGGCGTGGGCAAGAGCTTCAAGGACAACCGCGACCCGAACGGCGTCTACGTCA
ACCGCGACCTGGTGAAAGTCGCGAAGGACGGCACTCACTACCTGCAATACAGCTCGCCGCTGCCGGGCAACGCGCAAGTG
CTGGTGCCGAAACTCGGTTACACCGAATACCTGGCGAAGTGGGACATGGCGGTCGGTACGTCGGTCAACCTCGATGGCAT
CGAAGCGCAAGTGGCGGTGGTCGAGGCCAAGGTGCAGGAACGCATGCAGGGCGTGGTGCTGAGCATCGTCGGCGTGGCGG
TGGTGGTGCTGCTGGTGATCGCGGTAGCGGGGATGCTGCTGGCCAACACCATCCTGCGACCGCTGACCCTGATGAAAGCC
AACCTCGATGACATCGCGGCGGGCGAGGGCGACCTGACCCGGCGCCTGACCATCACCAGCCAGGACGAACTCGGCGAACT
GGCCGGCTCATTCAACCGTTTCGTCGACAAGATCCACGGCCTGGTGCGGCAGATCACCGAGATGACGTCGCAACTGACCG
GTTTGGTGACGCAGGTGTCGGATCAGGCCCAGCGCTCCGATCAGGCCATGGAGCGTCAGCGCCATGAAACCGATCAGGTC
GCCACGGCGATCAACGAAATGTCCGCGGCCGCGCAAGAAGTCGCCAAGAGCGCACAGAACGCCGCCGTCGCCGCGCAGCA
GACCGACGAAGAAGGCCAGACCGCCAAGCGCGTGGTGGCCGGCAGCATCAAGCAGATTCATGCGCTGGTGGACGACATCC
GCAGCAGCGGCGTGTCCCTCGACAGCCTGCAGCAGGACGTGTCGTCGATTGTCGGCGTGCTCGGGGTGATTCGCTCGATC
GCCGAACAGACCAACCTGCTGGCACTCAACGCCGCAATTGAAGCGGCCCGGGCCGGCGAGGCCGGGCGCGGGTTTGCGGT
GGTGGCGGATGAAGTGCGGGCGCTGGCTTCGCGCACGCAGATCAGCACTCAGGAAATTCAGGGGATGATCGATCGCTTGC
AGGCGGGGACGCAGTCGGCGGTTGAAGCGATGCGCCGTTCCAGCGAGGCGGGTGACGGCACGTCGGCCCAGGCCAATCAG
GCGGGGGCTTCGCTGGATGCGATGGCGGATCTGATTGCGACCATCAACTCGATGAACGCGCAGATTGCCAGTGCTGCCGA
GGAGCAGACGGCGGTGGCCGAAGAGATCAACCGCAGCGTGCATCAGATTGCGGTGGCGGTGGATAACGTGGCGGATGAGA
CACAGTTGGGGGCGCAGACATCGCGCAGTCTCGCGGAGTTGGGGCAGCGATTGGGCAAACTGGTCGGCCAGTTCCGTATC
TGA

Upstream 100 bases:

>100_bases
TCGGCGTCGAGGTGTCGATCTCAAGCCGCAGCTCAACTTTTGGTTTCGCGTGCCGTTAAAGCCTTTAACCACGCCAATAA
AACCAAAAGAGTGAGCCCCC

Downstream 100 bases:

>100_bases
CCCCCAAAGGCCCCCTCACCCTAACCCTCTCCCGGAGGGAGAGGGGACTGACCGCAGTGTCTTGCGTCATACATCGACCT
GAAAAATCGTGTCGATTATG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MRLSLKAKVLSLAVLPVLLFALVISLTTLFILQEQARNEVQQTRERLLGDAKATLASYVAVAMTTIKPLYDAAAPGDADA
RAQVIKLLSSIKYGKDGYFFGYDSETVRLFKANDPEGVGKSFKDNRDPNGVYVNRDLVKVAKDGTHYLQYSSPLPGNAQV
LVPKLGYTEYLAKWDMAVGTSVNLDGIEAQVAVVEAKVQERMQGVVLSIVGVAVVVLLVIAVAGMLLANTILRPLTLMKA
NLDDIAAGEGDLTRRLTITSQDELGELAGSFNRFVDKIHGLVRQITEMTSQLTGLVTQVSDQAQRSDQAMERQRHETDQV
ATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQTAKRVVAGSIKQIHALVDDIRSSGVSLDSLQQDVSSIVGVLGVIRSI
AEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQSAVEAMRRSSEAGDGTSAQANQ
AGASLDAMADLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDNVADETQLGAQTSRSLAELGQRLGKLVGQFRI

Sequences:

>Translated_560_residues
MRLSLKAKVLSLAVLPVLLFALVISLTTLFILQEQARNEVQQTRERLLGDAKATLASYVAVAMTTIKPLYDAAAPGDADA
RAQVIKLLSSIKYGKDGYFFGYDSETVRLFKANDPEGVGKSFKDNRDPNGVYVNRDLVKVAKDGTHYLQYSSPLPGNAQV
LVPKLGYTEYLAKWDMAVGTSVNLDGIEAQVAVVEAKVQERMQGVVLSIVGVAVVVLLVIAVAGMLLANTILRPLTLMKA
NLDDIAAGEGDLTRRLTITSQDELGELAGSFNRFVDKIHGLVRQITEMTSQLTGLVTQVSDQAQRSDQAMERQRHETDQV
ATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQTAKRVVAGSIKQIHALVDDIRSSGVSLDSLQQDVSSIVGVLGVIRSI
AEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQSAVEAMRRSSEAGDGTSAQANQ
AGASLDAMADLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDNVADETQLGAQTSRSLAELGQRLGKLVGQFRI
>Mature_560_residues
MRLSLKAKVLSLAVLPVLLFALVISLTTLFILQEQARNEVQQTRERLLGDAKATLASYVAVAMTTIKPLYDAAAPGDADA
RAQVIKLLSSIKYGKDGYFFGYDSETVRLFKANDPEGVGKSFKDNRDPNGVYVNRDLVKVAKDGTHYLQYSSPLPGNAQV
LVPKLGYTEYLAKWDMAVGTSVNLDGIEAQVAVVEAKVQERMQGVVLSIVGVAVVVLLVIAVAGMLLANTILRPLTLMKA
NLDDIAAGEGDLTRRLTITSQDELGELAGSFNRFVDKIHGLVRQITEMTSQLTGLVTQVSDQAQRSDQAMERQRHETDQV
ATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQTAKRVVAGSIKQIHALVDDIRSSGVSLDSLQQDVSSIVGVLGVIRSI
AEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQSAVEAMRRSSEAGDGTSAQANQ
AGASLDAMADLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDNVADETQLGAQTSRSLAELGQRLGKLVGQFRI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=30.1282051282051, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787690, Length=367, Percent_Identity=28.0653950953678, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=30.1724137931034, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI2367378, Length=360, Percent_Identity=28.6111111111111, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789453, Length=361, Percent_Identity=27.4238227146814, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59596; Mature: 59596

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLKAKVLSLAVLPVLLFALVISLTTLFILQEQARNEVQQTRERLLGDAKATLASYVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMTTIKPLYDAAAPGDADARAQVIKLLSSIKYGKDGYFFGYDSETVRLFKANDPEGVGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCC
SFKDNRDPNGVYVNRDLVKVAKDGTHYLQYSSPLPGNAQVLVPKLGYTEYLAKWDMAVGT
CCCCCCCCCCEEECHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCC
SVNLDGIEAQVAVVEAKVQERMQGVVLSIVGVAVVVLLVIAVAGMLLANTILRPLTLMKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLDDIAAGEGDLTRRLTITSQDELGELAGSFNRFVDKIHGLVRQITEMTSQLTGLVTQVS
CCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQAQRSDQAMERQRHETDQVATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQTAKRVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GSIKQIHALVDDIRSSGVSLDSLQQDVSSIVGVLGVIRSIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCC
AGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQSAVEAMRRSSEAGDGTSAQANQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHH
AGASLDAMADLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDNVADETQLGAQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRSLAELGQRLGKLVGQFRI
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLSLKAKVLSLAVLPVLLFALVISLTTLFILQEQARNEVQQTRERLLGDAKATLASYVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMTTIKPLYDAAAPGDADARAQVIKLLSSIKYGKDGYFFGYDSETVRLFKANDPEGVGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCC
SFKDNRDPNGVYVNRDLVKVAKDGTHYLQYSSPLPGNAQVLVPKLGYTEYLAKWDMAVGT
CCCCCCCCCCEEECHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCC
SVNLDGIEAQVAVVEAKVQERMQGVVLSIVGVAVVVLLVIAVAGMLLANTILRPLTLMKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLDDIAAGEGDLTRRLTITSQDELGELAGSFNRFVDKIHGLVRQITEMTSQLTGLVTQVS
CCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQAQRSDQAMERQRHETDQVATAINEMSAAAQEVAKSAQNAAVAAQQTDEEGQTAKRVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GSIKQIHALVDDIRSSGVSLDSLQQDVSSIVGVLGVIRSIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCC
AGRGFAVVADEVRALASRTQISTQEIQGMIDRLQAGTQSAVEAMRRSSEAGDGTSAQANQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHH
AGASLDAMADLIATINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDNVADETQLGAQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRSLAELGQRLGKLVGQFRI
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]