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The map label for this gene is yfcG [H]

Identifier: 77459974

GI number: 77459974

Start: 4240549

End: 4241256

Strand: Reverse

Name: yfcG [H]

Synonym: Pfl01_3752

Alternate gene names: 77459974

Gene position: 4241256-4240549 (Counterclockwise)

Preceding gene: 77459976

Following gene: 77459973

Centisome position: 65.87

GC content: 61.3

Gene sequence:

>708_bases
ATGCTACACATGACTGATCTGTCCGCGTTCCCGATCACCCAGAAATGGCCGGCGCAGTACCCTGACTGGATTCAGCTCTA
TTCCCTGCCGACCCCCAACGGCGTCAAGGTCTCGATCATGCTCGAAGAAATCGGCCTGCCGTACGAGCCGCACCGCGTGG
GCTTCGACACCAACGACCAAATGTCTGCGGAGTTCCTGTCGCTGAACCCGAACAACAAGATCCCGGCGATCATCGACCCC
CACGGCCCCGAGGACAAACCGCTGCCGTTGTTCGAGTCCGGCGCGATCCTGATCTACCTCGCCGACAAGAGCGGCCAATT
GCTGGCCCAGGAAGGCGCGCTGCGCTACGAAACCATTCAGTGGCTGATGTTCCAGATGGGCGGCATCGGTCCGATGTTCG
GCCAGCTCGGTTTCTTCAACAAATTCGCTGGCAAGGATTACGAAGACAAGCGTCCCCGTGACCGCTACGTCGAGGAAAGC
CGCCGCCTGCTCAACGTCCTGAACACCCGCCTGGAAGGGCGCGACTGGATCATGGGCGAGCGCTACACCATCGCCGACAT
TGCCACGTTCCCGTGGGTGCGCAACCTGATCGGCTTCTACGAAGCCGGCGATCTGGTCGGCATCAACAACTTCCCGAACG
TCACCCGGGTGCTGGAGCGCTTCCTGACACGGCCGGCGGTTGTGCGCGGCTTGACCATTCCTTCCTGA

Upstream 100 bases:

>100_bases
AGGATGTTGCGGATTTAAGTAAGCCGGCGGGCGAGGGCGTAAAGAACCCGAGCCAGAGCGCTGTTCGTGGATTATGCTCA
GGCCTTTCATTTGTGACTGG

Downstream 100 bases:

>100_bases
CCGTGCGGCAGCCGGGTGCGCAGATTGTTGCGTGCCCGGTAATGCACTGTTGATTGATCCAGGTTTGTACCCCGTCCCCC
GCAAGGCATAAGCTTCGCCC

Product: glutathione S-transferase-like protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLHMTDLSAFPITQKWPAQYPDWIQLYSLPTPNGVKVSIMLEEIGLPYEPHRVGFDTNDQMSAEFLSLNPNNKIPAIIDP
HGPEDKPLPLFESGAILIYLADKSGQLLAQEGALRYETIQWLMFQMGGIGPMFGQLGFFNKFAGKDYEDKRPRDRYVEES
RRLLNVLNTRLEGRDWIMGERYTIADIATFPWVRNLIGFYEAGDLVGINNFPNVTRVLERFLTRPAVVRGLTIPS

Sequences:

>Translated_235_residues
MLHMTDLSAFPITQKWPAQYPDWIQLYSLPTPNGVKVSIMLEEIGLPYEPHRVGFDTNDQMSAEFLSLNPNNKIPAIIDP
HGPEDKPLPLFESGAILIYLADKSGQLLAQEGALRYETIQWLMFQMGGIGPMFGQLGFFNKFAGKDYEDKRPRDRYVEES
RRLLNVLNTRLEGRDWIMGERYTIADIATFPWVRNLIGFYEAGDLVGINNFPNVTRVLERFLTRPAVVRGLTIPS
>Mature_235_residues
MLHMTDLSAFPITQKWPAQYPDWIQLYSLPTPNGVKVSIMLEEIGLPYEPHRVGFDTNDQMSAEFLSLNPNNKIPAIIDP
HGPEDKPLPLFESGAILIYLADKSGQLLAQEGALRYETIQWLMFQMGGIGPMFGQLGFFNKFAGKDYEDKRPRDRYVEES
RRLLNVLNTRLEGRDWIMGERYTIADIATFPWVRNLIGFYEAGDLVGINNFPNVTRVLERFLTRPAVVRGLTIPS

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=210, Percent_Identity=45.2380952380952, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI87082195, Length=219, Percent_Identity=39.7260273972603, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87081789, Length=208, Percent_Identity=28.8461538461538, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324100, Length=243, Percent_Identity=31.2757201646091, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI28571670, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549270, Length=197, Percent_Identity=27.4111675126904, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17933730, Length=201, Percent_Identity=27.363184079602, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26821; Mature: 26821

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHMTDLSAFPITQKWPAQYPDWIQLYSLPTPNGVKVSIMLEEIGLPYEPHRVGFDTNDQ
CEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCC
MSAEFLSLNPNNKIPAIIDPHGPEDKPLPLFESGAILIYLADKSGQLLAQEGALRYETIQ
CCEEEEEECCCCCCCEEECCCCCCCCCCCEECCCEEEEEEECCCCCEEECCCCHHHHHHH
WLMFQMGGIGPMFGQLGFFNKFAGKDYEDKRPRDRYVEESRRLLNVLNTRLEGRDWIMGE
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCC
RYTIADIATFPWVRNLIGFYEAGDLVGINNFPNVTRVLERFLTRPAVVRGLTIPS
CEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCHHHHHCCCCCC
>Mature Secondary Structure
MLHMTDLSAFPITQKWPAQYPDWIQLYSLPTPNGVKVSIMLEEIGLPYEPHRVGFDTNDQ
CEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCC
MSAEFLSLNPNNKIPAIIDPHGPEDKPLPLFESGAILIYLADKSGQLLAQEGALRYETIQ
CCEEEEEECCCCCCCEEECCCCCCCCCCCEECCCEEEEEEECCCCCEEECCCCHHHHHHH
WLMFQMGGIGPMFGQLGFFNKFAGKDYEDKRPRDRYVEESRRLLNVLNTRLEGRDWIMGE
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCC
RYTIADIATFPWVRNLIGFYEAGDLVGINNFPNVTRVLERFLTRPAVVRGLTIPS
CEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]