Click here to switch to the map view.

The map label for this gene is gltD [H]

Identifier: 77459664

GI number: 77459664

Start: 3926446

End: 3927891

Strand: Direct

Name: gltD [H]

Synonym: Pfl01_3442

Alternate gene names: 77459664

Gene position: 3926446-3927891 (Clockwise)

Preceding gene: 77459663

Following gene: 77459665

Centisome position: 60.98

GC content: 63.76

Gene sequence:

>1446_bases
ATGAGGCCAGTTCAGACACCACAAAAAACCACTGCCCGACAGAGGCAGAAAACCTCAATTAACCGTGAGGCAAAAACCGT
GATCGAGACCCTGAACCATCTCCCGCACCCGCAAGAAAGTGCGGCCGCCCTCGCCGGCCATTTCACCGATCTGGCGCCAC
CGCTCAACGACCGTCAGGCGCATCTGGAAGCCTCGCGCTGCCTGTATTGCTACGACGCGCCGTGCGTGAATGCATGCCCG
AGCGAGATCGACATTCCGTCGTTCATCCGCAATATCCATCAGGACAACGTGCCCGGCGCGGCGCAGAAAATCCTCTCGGC
GAACATCCTCGGCGGCAGTTGCGCGCGGGTCTGTCCGACCGAAATCCTCTGCCAGCAAGCCTGCGTGCGCAACAACGCCC
ACGAATGCGCACCGGTACTGATCGGCCTGCTGCAGCGCTACGCCGTGGACAACGCGAACTTTACCGAGCATCCGTTCCAG
CGCGCCGCCGCAACCGGCAAACGCATCGCGGTGGTCGGTGCCGGCCCGGCGGGTTTGTCCTGCGCGCATCGCAGCGCCAT
GCACGGTCACGAGGTGGTGATTTTCGAAGCACGGGAGAAGGCTGGCGGGCTCAACGAATACGGGATCGCCAAATACAAAC
TGGTGGATGACTACGCGCAGAAGGAGCTGGATTTCCTCCTGCAGATCGGCGGCATCGAAATCCGTCACGGCCAGAAACTC
GGTGAGAATCTGACCCTCAGCGAACTGCATCAACAGTTCGACGCGGTGTTCCTCGGCCTCGGCCTGAACGCGAGCAAGCA
ACTCGGCCTGCCCCACGAAGACGCCCCCGGCCTGCTCGCCGCCACCGACTACATCCGCGAACTGCGCCAGGCCGATGACC
TGTCGCAACTGCCGCTGGCCGAACGTTGCATCGTCCTCGGTGCCGGCAATACCGCCATCGACATGGCCGTGCAAATGGCC
CGCCTCGGCGCCCGCGACGTCAATCTGGTCTATCGCCGTGGCGCGGCAGACATGGGCGCCACCGGCCATGAGCAGGACAT
CGCCAAGGCCAATCAGGTGCGGTTGCTGACATGGGCGCAACCGGACGAAGTGCTGCTCGACGCGCAAGGCAAGGTTCGTG
GCATGCGTTTCGCCCGTACGCATCTGGTGGACGGTCGCCTGCAAACCACGGGCGAGACTTTCGAGCTGGCCGCCGATGCG
ATCTTCAAAGCCATCGGCCAGGCCTTCGACGGCAGCGCCCTCGCCGACCCGCTGGCCCGCGAACTCAAGCGTCAGGGCGA
ACGCATCCAGGTCGATGAAAACCTGCGCACCAGCATCCCCGGCGTGTACGCAGGCGGCGACTGCACCAGCCTCGATCAGG
ACCTGACCGTGCAAGCGGTGCAACACGGCAAGCGCGCCGCCGAGGCGATCAACGCTCAACTGATGCTCAACGTGGAGGCT
GCGTAA

Upstream 100 bases:

>100_bases
TGTGAAACGCTGAAAGCGGCCTTCGGCCTCATCGCGGGCAAGCCCGCTCCCACAGGTTTTATGCGCGCCGTAGATCCCTG
TGGGAGCTGGCTTGCCAGCG

Downstream 100 bases:

>100_bases
ATGGCCGATCTCTCGATAGTCTTCGCCGGTATCAAAGCCCCCAACCCGTTCTGGCTGGCCTCCGCGCCGCCGACCGACAA
GGCCTACAACGTGGTGCGCG

Product: putative oxidoreductase

Products: NA

Alternate protein names: Glutamate synthase subunit beta; GLTS beta chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRPVQTPQKTTARQRQKTSINREAKTVIETLNHLPHPQESAAALAGHFTDLAPPLNDRQAHLEASRCLYCYDAPCVNACP
SEIDIPSFIRNIHQDNVPGAAQKILSANILGGSCARVCPTEILCQQACVRNNAHECAPVLIGLLQRYAVDNANFTEHPFQ
RAAATGKRIAVVGAGPAGLSCAHRSAMHGHEVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLQIGGIEIRHGQKL
GENLTLSELHQQFDAVFLGLGLNASKQLGLPHEDAPGLLAATDYIRELRQADDLSQLPLAERCIVLGAGNTAIDMAVQMA
RLGARDVNLVYRRGAADMGATGHEQDIAKANQVRLLTWAQPDEVLLDAQGKVRGMRFARTHLVDGRLQTTGETFELAADA
IFKAIGQAFDGSALADPLARELKRQGERIQVDENLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAINAQLMLNVEA
A

Sequences:

>Translated_481_residues
MRPVQTPQKTTARQRQKTSINREAKTVIETLNHLPHPQESAAALAGHFTDLAPPLNDRQAHLEASRCLYCYDAPCVNACP
SEIDIPSFIRNIHQDNVPGAAQKILSANILGGSCARVCPTEILCQQACVRNNAHECAPVLIGLLQRYAVDNANFTEHPFQ
RAAATGKRIAVVGAGPAGLSCAHRSAMHGHEVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLQIGGIEIRHGQKL
GENLTLSELHQQFDAVFLGLGLNASKQLGLPHEDAPGLLAATDYIRELRQADDLSQLPLAERCIVLGAGNTAIDMAVQMA
RLGARDVNLVYRRGAADMGATGHEQDIAKANQVRLLTWAQPDEVLLDAQGKVRGMRFARTHLVDGRLQTTGETFELAADA
IFKAIGQAFDGSALADPLARELKRQGERIQVDENLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAINAQLMLNVEA
A
>Mature_481_residues
MRPVQTPQKTTARQRQKTSINREAKTVIETLNHLPHPQESAAALAGHFTDLAPPLNDRQAHLEASRCLYCYDAPCVNACP
SEIDIPSFIRNIHQDNVPGAAQKILSANILGGSCARVCPTEILCQQACVRNNAHECAPVLIGLLQRYAVDNANFTEHPFQ
RAAATGKRIAVVGAGPAGLSCAHRSAMHGHEVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLQIGGIEIRHGQKL
GENLTLSELHQQFDAVFLGLGLNASKQLGLPHEDAPGLLAATDYIRELRQADDLSQLPLAERCIVLGAGNTAIDMAVQMA
RLGARDVNLVYRRGAADMGATGHEQDIAKANQVRLLTWAQPDEVLLDAQGKVRGMRFARTHLVDGRLQTTGETFELAADA
IFKAIGQAFDGSALADPLARELKRQGERIQVDENLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAINAQLMLNVEA
A

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=465, Percent_Identity=33.5483870967742, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI237757300, Length=108, Percent_Identity=44.4444444444444, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789606, Length=464, Percent_Identity=30.6034482758621, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1788468, Length=429, Percent_Identity=34.032634032634, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1788811, Length=444, Percent_Identity=32.2072072072072, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87082180, Length=458, Percent_Identity=31.6593886462882, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1789243, Length=409, Percent_Identity=29.0953545232274, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71984108, Length=460, Percent_Identity=32.6086956521739, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17570289, Length=458, Percent_Identity=24.6724890829694, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320030, Length=472, Percent_Identity=25.4237288135593, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24640763, Length=464, Percent_Identity=34.2672413793103, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI18858217, Length=464, Percent_Identity=34.2672413793103, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI28574881, Length=456, Percent_Identity=25.6578947368421, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24665539, Length=456, Percent_Identity=25.6578947368421, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24665547, Length=456, Percent_Identity=25.6578947368421, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24665543, Length=456, Percent_Identity=25.6578947368421, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006
- InterPro:   IPR009051
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 52051; Mature: 52051

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVQTPQKTTARQRQKTSINREAKTVIETLNHLPHPQESAAALAGHFTDLAPPLNDRQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHH
HLEASRCLYCYDAPCVNACPSEIDIPSFIRNIHQDNVPGAAQKILSANILGGSCARVCPT
HHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCH
EILCQQACVRNNAHECAPVLIGLLQRYAVDNANFTEHPFQRAAATGKRIAVVGAGPAGLS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCH
CAHRSAMHGHEVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLQIGGIEIRHGQKL
HHHHHHCCCCEEEEEECHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEECCHHH
GENLTLSELHQQFDAVFLGLGLNASKQLGLPHEDAPGLLAATDYIRELRQADDLSQLPLA
CCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCHH
ERCIVLGAGNTAIDMAVQMARLGARDVNLVYRRGAADMGATGHEQDIAKANQVRLLTWAQ
HEEEEEECCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHCCCCEEEEEECC
PDEVLLDAQGKVRGMRFARTHLVDGRLQTTGETFELAADAIFKAIGQAFDGSALADPLAR
CCCEEEECCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELKRQGERIQVDENLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAINAQLMLNVEA
HHHHCCCEEEECCCHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEC
A
C
>Mature Secondary Structure
MRPVQTPQKTTARQRQKTSINREAKTVIETLNHLPHPQESAAALAGHFTDLAPPLNDRQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHH
HLEASRCLYCYDAPCVNACPSEIDIPSFIRNIHQDNVPGAAQKILSANILGGSCARVCPT
HHHHHCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCH
EILCQQACVRNNAHECAPVLIGLLQRYAVDNANFTEHPFQRAAATGKRIAVVGAGPAGLS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCH
CAHRSAMHGHEVVIFEAREKAGGLNEYGIAKYKLVDDYAQKELDFLLQIGGIEIRHGQKL
HHHHHHCCCCEEEEEECHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEECCHHH
GENLTLSELHQQFDAVFLGLGLNASKQLGLPHEDAPGLLAATDYIRELRQADDLSQLPLA
CCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCHH
ERCIVLGAGNTAIDMAVQMARLGARDVNLVYRRGAADMGATGHEQDIAKANQVRLLTWAQ
HEEEEEECCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHCCCCEEEEEECC
PDEVLLDAQGKVRGMRFARTHLVDGRLQTTGETFELAADAIFKAIGQAFDGSALADPLAR
CCCEEEECCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELKRQGERIQVDENLRTSIPGVYAGGDCTSLDQDLTVQAVQHGKRAAEAINAQLMLNVEA
HHHHCCCEEEECCCHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 9298646; 9600841; 2643092 [H]