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The map label for this gene is iorB [H]

Identifier: 77459647

GI number: 77459647

Start: 3905325

End: 3907532

Strand: Reverse

Name: iorB [H]

Synonym: Pfl01_3425

Alternate gene names: 77459647

Gene position: 3907532-3905325 (Counterclockwise)

Preceding gene: 77459648

Following gene: 77459646

Centisome position: 60.69

GC content: 63.36

Gene sequence:

>2208_bases
ATGAGCCTCATCGACGGCACCCTTCAAGAACCCTCGCGCCGGGTGTTTCTCAAACAGGCGGTGACAGTGGCGTCCGGTCT
GGCGATTGCGCTGTACCTGCCTTCCGGTGCGGCGGCGACTGAGCCGAAAACCTCGACCACTGAATTCGAACCCAACGCCT
GGGTGCGCGTGCTGCCCGACGGCACGGTGAAACTGGTGGTGCACAAGCACGATTCCGGCACCGGCACCCAGACCGCGCTG
GCCGCATGTGTAGCCGAGGAACTGGACGTCAACCCGATGACCGTGCAGGTCATCACCCCGGAAAATCCGTTCTTCGAAAC
CTACATTCATCCGGTCTGGAAAGTCTTCTCCACCGGCGGCAGCACCAGTGTGTCGCTGGAGTACGATCGCTTGCGCATGG
CTGGCGCCACGGCGCGGGCGCTGCTGATCAGTGCGGCGGCGCAGCAGTGGAAAGTCAGCCCCGACAGTTGCTCCACCGAA
GAAGGCCGGGTCGTGCATGCGTCGAGCAAGCGCAGCCTCGGCTACGGCGAAGTGGCCGGCGCGGCGGCGCATCTGTCGGC
ACCGGCCAACGTCACGCTGAAGGATCCGGCGCAGTTCAAATACATCGGAAAATTGCGTCACAAACGCGATGCGGCGGCCA
AGGTTTGCGGGCGCTTCAATTACAGCATCGACGTGCAGTTGCCGGGGATGTTGGTGGCGGTAATCCAGCGTGCGCCGGTG
GTGGGCGCGAAGGTTGTCGCAGTGGATTCGGCGGCCGCATTGCAGGTGCCGGGCGTGCGCAAGGTGATCGCGGTTCCAGG
ACGTCCGGACGTGCTCGGCGGCAACCTCGAAGGCGTCGCGGTGCTAGCCGAAACGTTCTGGGCTGCGCAGCAGGGACGTC
AGTTGCTGGAGATCAAATGGAGCGACTCGCCGCTGGCCGGCTTCGACAGCGCCGATCTGGCCAAGGCACAGATCGCAGCG
ATCAGCGACCCGGCAACGCAAACCGTCAAAGCCATGGCCCAGGGCGATGTCGCCGGGCAATGGCCGGGTGCTGCGAAGCT
GCTCGAAGCCGATTACACCATGCCCTACAAGGTGCAAAACCCGCTGGAGCCGATCTGCATCACTGCGCAAGTCAAGGACA
AGGCAATCACCTATTGGGGCGGCGTGCAGGTGCCGTCCTCGGCACTGGAAGCGGCGCAGACCGTGTGCGGCATCGCCAAG
GACAAGGTCACCATCCATGAACTGGTGTCCGGTGGCAGCTTCGGTGCGCGGGAAGCCAAATACTGGTTGTTCGAGGTCGC
GTATCTGGCGCAGAAAACCGGCGTGCCGGTGAAACTGCTCAACAGTCGCGAAGACGAAATGCACGCGCTGTTCTATCACC
CGGCCACGCTGCATCGGGTGAAAGGTGCACTGGATGCCCAGGGCAAACTCACGGCGTTGCAACTGCATGCAGTGTCACCG
GCCTCGCCGGAACAGTGGGAGCCGGGCTATTTCGAGCGTCCGGATCACATGGATTACAGCACCACCGAAGCAATCACCGC
GTGGGACTTCGCCTACCGTCCGCCGCACCTGGAGCTGAACTGGGTCAAGCACGAAAGCAACGTGCCCAGCGGTTGGTATC
GCTCGGTCAGTTTCATTCCCAACGTGTTCGCTGTGGAGAGCTTTATGGATGAACTGGCCCATGCGGCCGGCAAAGATCCG
CTGGCGTTCAGACTGGCCAGCATGCAGGAGCGGCCATGGCATGTCGCTGTGTTGAAGCAGGCCGCCGAACGCGCCGGTTG
GGGGCAGAAGCTGCCGCCGGACACGGCGCTGGGGATTGCGACCAATCAGGGTTACACCAGTTTCATCGCCGTGGTGGCGC
GGGTCGCGAAGGTGGATGGCAAGGCGCGGGTCGAGAAGCTGACCTGCGTGGTCGATTGCGGTCTGGCGGTGTCGCCGGGC
GGTGTCGAAGAGCAGATTTACGGCGGACTGATGTGGGGCCTCGGGCATGCGCTGTTCGACCGTCTCGACATCCAGCAGGG
CCGGGTGGTGCAGAGCAATTTTCACGACTATCGCGTCACGCGCATGTCGGACATGCCGCCCGTGGACATCCTCGTGCTCA
ATGGCCAGCCGGATAAACCGGGCGGTGTGGGAGAACTGGGCAGTCCTTCGGTGGTCCCGGCGATTGCCAATGCGCTATTC
AGCCTGACCGGGGTGCGTCAGCGTTCCACGCCACTGAACCTGGGGTAA

Upstream 100 bases:

>100_bases
CGATCCGCAACGCGATGTCCGGGAATATCTGCCGCTGCGGCACGTACGGGCGCATCAACAAAGCGATCAAACGGGCGGCG
AATGCGCCGAAGGAGGCGTG

Downstream 100 bases:

>100_bases
GCCGCCATGGACCTGCGTTTGCTGCGGTACTTCATGGCCCTGGCCGATGAGCTGCACTTTGGCCGCGCCGCCGAACGGCT
GCACATCTGCCAGCCGCCGC

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MSLIDGTLQEPSRRVFLKQAVTVASGLAIALYLPSGAAATEPKTSTTEFEPNAWVRVLPDGTVKLVVHKHDSGTGTQTAL
AACVAEELDVNPMTVQVITPENPFFETYIHPVWKVFSTGGSTSVSLEYDRLRMAGATARALLISAAAQQWKVSPDSCSTE
EGRVVHASSKRSLGYGEVAGAAAHLSAPANVTLKDPAQFKYIGKLRHKRDAAAKVCGRFNYSIDVQLPGMLVAVIQRAPV
VGAKVVAVDSAAALQVPGVRKVIAVPGRPDVLGGNLEGVAVLAETFWAAQQGRQLLEIKWSDSPLAGFDSADLAKAQIAA
ISDPATQTVKAMAQGDVAGQWPGAAKLLEADYTMPYKVQNPLEPICITAQVKDKAITYWGGVQVPSSALEAAQTVCGIAK
DKVTIHELVSGGSFGAREAKYWLFEVAYLAQKTGVPVKLLNSREDEMHALFYHPATLHRVKGALDAQGKLTALQLHAVSP
ASPEQWEPGYFERPDHMDYSTTEAITAWDFAYRPPHLELNWVKHESNVPSGWYRSVSFIPNVFAVESFMDELAHAAGKDP
LAFRLASMQERPWHVAVLKQAAERAGWGQKLPPDTALGIATNQGYTSFIAVVARVAKVDGKARVEKLTCVVDCGLAVSPG
GVEEQIYGGLMWGLGHALFDRLDIQQGRVVQSNFHDYRVTRMSDMPPVDILVLNGQPDKPGGVGELGSPSVVPAIANALF
SLTGVRQRSTPLNLG

Sequences:

>Translated_735_residues
MSLIDGTLQEPSRRVFLKQAVTVASGLAIALYLPSGAAATEPKTSTTEFEPNAWVRVLPDGTVKLVVHKHDSGTGTQTAL
AACVAEELDVNPMTVQVITPENPFFETYIHPVWKVFSTGGSTSVSLEYDRLRMAGATARALLISAAAQQWKVSPDSCSTE
EGRVVHASSKRSLGYGEVAGAAAHLSAPANVTLKDPAQFKYIGKLRHKRDAAAKVCGRFNYSIDVQLPGMLVAVIQRAPV
VGAKVVAVDSAAALQVPGVRKVIAVPGRPDVLGGNLEGVAVLAETFWAAQQGRQLLEIKWSDSPLAGFDSADLAKAQIAA
ISDPATQTVKAMAQGDVAGQWPGAAKLLEADYTMPYKVQNPLEPICITAQVKDKAITYWGGVQVPSSALEAAQTVCGIAK
DKVTIHELVSGGSFGAREAKYWLFEVAYLAQKTGVPVKLLNSREDEMHALFYHPATLHRVKGALDAQGKLTALQLHAVSP
ASPEQWEPGYFERPDHMDYSTTEAITAWDFAYRPPHLELNWVKHESNVPSGWYRSVSFIPNVFAVESFMDELAHAAGKDP
LAFRLASMQERPWHVAVLKQAAERAGWGQKLPPDTALGIATNQGYTSFIAVVARVAKVDGKARVEKLTCVVDCGLAVSPG
GVEEQIYGGLMWGLGHALFDRLDIQQGRVVQSNFHDYRVTRMSDMPPVDILVLNGQPDKPGGVGELGSPSVVPAIANALF
SLTGVRQRSTPLNLG
>Mature_734_residues
SLIDGTLQEPSRRVFLKQAVTVASGLAIALYLPSGAAATEPKTSTTEFEPNAWVRVLPDGTVKLVVHKHDSGTGTQTALA
ACVAEELDVNPMTVQVITPENPFFETYIHPVWKVFSTGGSTSVSLEYDRLRMAGATARALLISAAAQQWKVSPDSCSTEE
GRVVHASSKRSLGYGEVAGAAAHLSAPANVTLKDPAQFKYIGKLRHKRDAAAKVCGRFNYSIDVQLPGMLVAVIQRAPVV
GAKVVAVDSAAALQVPGVRKVIAVPGRPDVLGGNLEGVAVLAETFWAAQQGRQLLEIKWSDSPLAGFDSADLAKAQIAAI
SDPATQTVKAMAQGDVAGQWPGAAKLLEADYTMPYKVQNPLEPICITAQVKDKAITYWGGVQVPSSALEAAQTVCGIAKD
KVTIHELVSGGSFGAREAKYWLFEVAYLAQKTGVPVKLLNSREDEMHALFYHPATLHRVKGALDAQGKLTALQLHAVSPA
SPEQWEPGYFERPDHMDYSTTEAITAWDFAYRPPHLELNWVKHESNVPSGWYRSVSFIPNVFAVESFMDELAHAAGKDPL
AFRLASMQERPWHVAVLKQAAERAGWGQKLPPDTALGIATNQGYTSFIAVVARVAKVDGKARVEKLTCVVDCGLAVSPGG
VEEQIYGGLMWGLGHALFDRLDIQQGRVVQSNFHDYRVTRMSDMPPVDILVLNGQPDKPGGVGELGSPSVVPAIANALFS
LTGVRQRSTPLNLG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=127, Percent_Identity=33.0708661417323, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78886; Mature: 78755

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDGTLQEPSRRVFLKQAVTVASGLAIALYLPSGAAATEPKTSTTEFEPNAWVRVLPD
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCC
GTVKLVVHKHDSGTGTQTALAACVAEELDVNPMTVQVITPENPFFETYIHPVWKVFSTGG
CEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
STSVSLEYDRLRMAGATARALLISAAAQQWKVSPDSCSTEEGRVVHASSKRSLGYGEVAG
CEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHC
AAAHLSAPANVTLKDPAQFKYIGKLRHKRDAAAKVCGRFNYSIDVQLPGMLVAVIQRAPV
CHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCC
VGAKVVAVDSAAALQVPGVRKVIAVPGRPDVLGGNLEGVAVLAETFWAAQQGRQLLEIKW
CCEEEEEECCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
SDSPLAGFDSADLAKAQIAAISDPATQTVKAMAQGDVAGQWPGAAKLLEADYTMPYKVQN
CCCCCCCCCCCHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCEEECC
PLEPICITAQVKDKAITYWGGVQVPSSALEAAQTVCGIAKDKVTIHELVSGGSFGAREAK
CCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCCCHHH
YWLFEVAYLAQKTGVPVKLLNSREDEMHALFYHPATLHRVKGALDAQGKLTALQLHAVSP
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEEEECCC
ASPEQWEPGYFERPDHMDYSTTEAITAWDFAYRPPHLELNWVKHESNVPSGWYRSVSFIP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHCC
NVFAVESFMDELAHAAGKDPLAFRLASMQERPWHVAVLKQAAERAGWGQKLPPDTALGIA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
TNQGYTSFIAVVARVAKVDGKARVEKLTCVVDCGLAVSPGGVEEQIYGGLMWGLGHALFD
ECCCHHHHHHHHHHHHHCCCHHHHEEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHH
RLDIQQGRVVQSNFHDYRVTRMSDMPPVDILVLNGQPDKPGGVGELGSPSVVPAIANALF
HHCCCCCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
SLTGVRQRSTPLNLG
HHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLIDGTLQEPSRRVFLKQAVTVASGLAIALYLPSGAAATEPKTSTTEFEPNAWVRVLPD
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCC
GTVKLVVHKHDSGTGTQTALAACVAEELDVNPMTVQVITPENPFFETYIHPVWKVFSTGG
CEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
STSVSLEYDRLRMAGATARALLISAAAQQWKVSPDSCSTEEGRVVHASSKRSLGYGEVAG
CEEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHC
AAAHLSAPANVTLKDPAQFKYIGKLRHKRDAAAKVCGRFNYSIDVQLPGMLVAVIQRAPV
CHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCC
VGAKVVAVDSAAALQVPGVRKVIAVPGRPDVLGGNLEGVAVLAETFWAAQQGRQLLEIKW
CCEEEEEECCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
SDSPLAGFDSADLAKAQIAAISDPATQTVKAMAQGDVAGQWPGAAKLLEADYTMPYKVQN
CCCCCCCCCCCHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCEEECC
PLEPICITAQVKDKAITYWGGVQVPSSALEAAQTVCGIAKDKVTIHELVSGGSFGAREAK
CCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCCCHHH
YWLFEVAYLAQKTGVPVKLLNSREDEMHALFYHPATLHRVKGALDAQGKLTALQLHAVSP
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEEEECCC
ASPEQWEPGYFERPDHMDYSTTEAITAWDFAYRPPHLELNWVKHESNVPSGWYRSVSFIP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHCC
NVFAVESFMDELAHAAGKDPLAFRLASMQERPWHVAVLKQAAERAGWGQKLPPDTALGIA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
TNQGYTSFIAVVARVAKVDGKARVEKLTCVVDCGLAVSPGGVEEQIYGGLMWGLGHALFD
ECCCHHHHHHHHHHHHHCCCHHHHEEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHH
RLDIQQGRVVQSNFHDYRVTRMSDMPPVDILVLNGQPDKPGGVGELGSPSVVPAIANALF
HHCCCCCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
SLTGVRQRSTPLNLG
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]