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The map label for this gene is ttdR [H]

Identifier: 77459579

GI number: 77459579

Start: 3831543

End: 3832430

Strand: Reverse

Name: ttdR [H]

Synonym: Pfl01_3357

Alternate gene names: 77459579

Gene position: 3832430-3831543 (Counterclockwise)

Preceding gene: 77459583

Following gene: 77459578

Centisome position: 59.52

GC content: 62.61

Gene sequence:

>888_bases
ATGTTCGACTGGAACGACCTGCGGTTCTTTCTCGAGTTGCAACGCAGCGGGCGCTTGCTCACTGCCGCCCGCCGCCTGAA
CACCACTCACGCCACCGTGGCCCGGCACATCGAGGCCATCGAAAAAAGCCTCGGCACCGCGCTCTTCGTCCAGCACGCCC
AAGGCTACGAAATGACTCCGGCGGGGGAGGCGCTGCTCAAACACGCCGAAGCCATGGAAAACGTCGCGCTGCTGGCTCAG
GAAGAAATCACCCAATCGACGGCGCCGCTGGGCAAGATCCGCGTCGGGGTCACCGAAGGCCTCGGCATCATGTTTCTCGC
CAGCCGCATGATCGGGTTGTTCGAACGCTACCTGGGACTGGAAGTGGAACTGGTGGCGGTGCCGCGCTTCGTCAGCATCC
TCAATCGCGAGGCGGAAATCAGCATTCACCTTGAACGGCCGGCGGCGGACATGCTGGTCACCCGCAAACTCACCGACTAC
CGACTCGCGCTCTATGCCAGCCGCGCCTACCTGGACAACGCGCCGCCATTGCGCAGCCGCGAGGATCTTGGCCGGCATGC
GTGGATCGGCTATGTCGATGATCTGCTGTTCAGTCAGGAGCTGATGTTTCTCAACAGCTTCTGTCGCAACCCACGGGTGG
TGTTTCACAGCACCAGCGTGATCGCCCAGCAGCAGGCGGCGCGCTCGGGGCTGGGGATTGCGGTGCTGCCTTGTTACATG
GCGGCGTCGGACCCGGATCTGGTGGCGCTGTTGCCGGATGAGAGCATTGAGCGCAGTTACTGGATCAGTACGCGGCGCGA
GTTGCACAAATCGGTGCGGTTGCGGGTGGTCTGGGATTACGTCGTGGGCTTGTGCGAAGGCGAGCGCGAGTTGTTAATGG
GCCAGTAA

Upstream 100 bases:

>100_bases
CATCCTAGTTGTTAGCTTTCGTCAAAAGAATGTTAGTTTTTGCGCAGCCGCTGTGCGTTTTCAAACAGCGCTTCCTGACG
ATAGCCAACAAGGACAAGCC

Downstream 100 bases:

>100_bases
AGACGGCTGTTTCATGCAACTAAAACGCTTGGCAAAAGGTCATTCGATTTGCGGAGGTTGAGTCATCTCGCAGAACCTCG
ACAACGAAGACGTTACCCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAIEKSLGTALFVQHAQGYEMTPAGEALLKHAEAMENVALLAQ
EEITQSTAPLGKIRVGVTEGLGIMFLASRMIGLFERYLGLEVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLTDY
RLALYASRAYLDNAPPLRSREDLGRHAWIGYVDDLLFSQELMFLNSFCRNPRVVFHSTSVIAQQQAARSGLGIAVLPCYM
AASDPDLVALLPDESIERSYWISTRRELHKSVRLRVVWDYVVGLCEGERELLMGQ

Sequences:

>Translated_295_residues
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAIEKSLGTALFVQHAQGYEMTPAGEALLKHAEAMENVALLAQ
EEITQSTAPLGKIRVGVTEGLGIMFLASRMIGLFERYLGLEVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLTDY
RLALYASRAYLDNAPPLRSREDLGRHAWIGYVDDLLFSQELMFLNSFCRNPRVVFHSTSVIAQQQAARSGLGIAVLPCYM
AASDPDLVALLPDESIERSYWISTRRELHKSVRLRVVWDYVVGLCEGERELLMGQ
>Mature_295_residues
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAIEKSLGTALFVQHAQGYEMTPAGEALLKHAEAMENVALLAQ
EEITQSTAPLGKIRVGVTEGLGIMFLASRMIGLFERYLGLEVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLTDY
RLALYASRAYLDNAPPLRSREDLGRHAWIGYVDDLLFSQELMFLNSFCRNPRVVFHSTSVIAQQQAARSGLGIAVLPCYM
AASDPDLVALLPDESIERSYWISTRRELHKSVRLRVVWDYVVGLCEGERELLMGQ

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=25.752508361204, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33301; Mature: 33301

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAIEKSLGTALFVQHAQGYEMTP
CCCHHHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
AGEALLKHAEAMENVALLAQEEITQSTAPLGKIRVGVTEGLGIMFLASRMIGLFERYLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHCC
EVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLTDYRLALYASRAYLDNAPPLRSR
EEEEEEHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
EDLGRHAWIGYVDDLLFSQELMFLNSFCRNPRVVFHSTSVIAQQQAARSGLGIAVLPCYM
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHH
AASDPDLVALLPDESIERSYWISTRRELHKSVRLRVVWDYVVGLCEGERELLMGQ
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAIEKSLGTALFVQHAQGYEMTP
CCCHHHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
AGEALLKHAEAMENVALLAQEEITQSTAPLGKIRVGVTEGLGIMFLASRMIGLFERYLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHCC
EVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLTDYRLALYASRAYLDNAPPLRSR
EEEEEEHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
EDLGRHAWIGYVDDLLFSQELMFLNSFCRNPRVVFHSTSVIAQQQAARSGLGIAVLPCYM
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHH
AASDPDLVALLPDESIERSYWISTRRELHKSVRLRVVWDYVVGLCEGERELLMGQ
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]