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The map label for this gene is hsaB [H]

Identifier: 77459484

GI number: 77459484

Start: 3744774

End: 3745259

Strand: Direct

Name: hsaB [H]

Synonym: Pfl01_3262

Alternate gene names: 77459484

Gene position: 3744774-3745259 (Clockwise)

Preceding gene: 77459481

Following gene: 77459485

Centisome position: 58.16

GC content: 61.73

Gene sequence:

>486_bases
ATGATCGATGCTGCCGTCTACAAACAAGTCATGGGCTCGTTCCCGTCCGGCGTTACCGTCATCACCACGCTGGATGACGA
CGGCCAGATCGTCGGCCTGACCGCCAGCGCCTTCAGCTCGCTGTCGATGGACCCGGCGCTGGTGCTGTTCTGCCCCAACT
ACAGTTCCGATTCCTACCCCGTCCTGATCAAGAACAAACGCTTTGCCATTCACGTGTTGTCCGGCGGTCAGCAGAGCGAA
GCCTATGCCTTCGCCCGCAAAGGCAAGGACAAGGCGCAGGGCATCGAGTGGACGCTGAGCGAACTGGGCAACCCGATACT
GGCCAACGCGACAGCTATCATCGAATGTGAGCTGTGGCGCGAATACGAAGGCGGCGACCACGCGATCATGGTCGGCGCGG
TGAAGAACCTCATTCTCCCTCAGCAGGACGCCGGCCCGCTGGTGTACTGCCACGGCAAGATGGGCGCCCTGTCCGCCTTC
GCCTGA

Upstream 100 bases:

>100_bases
ATCGTTTCACCAAAAAAGCGCTTGCAATCGATGTATTACGGTATACCATCAGACCCATAAACACATAAAAACACGCTTCA
CCGCACTCGAGGATTGACCA

Downstream 100 bases:

>100_bases
TCCGCACGATTGCACTTAAACAGGCCGGCAAGCGACCGGCCGACCACAAGAGATTTGAGGTAGCGTCATGAAATTTTCCC
TGTTCGTACACATGGAACGC

Product: flavin reductase-like protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MIDAAVYKQVMGSFPSGVTVITTLDDDGQIVGLTASAFSSLSMDPALVLFCPNYSSDSYPVLIKNKRFAIHVLSGGQQSE
AYAFARKGKDKAQGIEWTLSELGNPILANATAIIECELWREYEGGDHAIMVGAVKNLILPQQDAGPLVYCHGKMGALSAF
A

Sequences:

>Translated_161_residues
MIDAAVYKQVMGSFPSGVTVITTLDDDGQIVGLTASAFSSLSMDPALVLFCPNYSSDSYPVLIKNKRFAIHVLSGGQQSE
AYAFARKGKDKAQGIEWTLSELGNPILANATAIIECELWREYEGGDHAIMVGAVKNLILPQQDAGPLVYCHGKMGALSAF
A
>Mature_161_residues
MIDAAVYKQVMGSFPSGVTVITTLDDDGQIVGLTASAFSSLSMDPALVLFCPNYSSDSYPVLIKNKRFAIHVLSGGQQSE
AYAFARKGKDKAQGIEWTLSELGNPILANATAIIECELWREYEGGDHAIMVGAVKNLILPQQDAGPLVYCHGKMGALSAF
A

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 17188; Mature: 17188

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAAVYKQVMGSFPSGVTVITTLDDDGQIVGLTASAFSSLSMDPALVLFCPNYSSDSYP
CCCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCCE
VLIKNKRFAIHVLSGGQQSEAYAFARKGKDKAQGIEWTLSELGNPILANATAIIECELWR
EEEECCEEEEEEECCCCCCHHHHHHHCCCCCCCCCEEEHHHCCCEEEECCEEEEEEEEEE
EYEGGDHAIMVGAVKNLILPQQDAGPLVYCHGKMGALSAFA
CCCCCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MIDAAVYKQVMGSFPSGVTVITTLDDDGQIVGLTASAFSSLSMDPALVLFCPNYSSDSYP
CCCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCCE
VLIKNKRFAIHVLSGGQQSEAYAFARKGKDKAQGIEWTLSELGNPILANATAIIECELWR
EEEECCEEEEEEECCCCCCHHHHHHHCCCCCCCCCEEEHHHCCCEEEECCEEEEEEEEEE
EYEGGDHAIMVGAVKNLILPQQDAGPLVYCHGKMGALSAFA
CCCCCCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA