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The map label for this gene is ppx [H]

Identifier: 77459469

GI number: 77459469

Start: 3727380

End: 3728315

Strand: Direct

Name: ppx [H]

Synonym: Pfl01_3247

Alternate gene names: 77459469

Gene position: 3727380-3728315 (Clockwise)

Preceding gene: 77459466

Following gene: 77459470

Centisome position: 57.89

GC content: 63.25

Gene sequence:

>936_bases
ATGAAAGAAGACACCTCGCTGTTTGCCGCCATCGACCTCGGTTCCAATGCCTTTCGCATGATGATCGGCCAGTCGGTACG
CAGCAGAAAGGGCTTCATGATCCAGGAGGTCAAAACCTTGCGTGAGCCGGTGCGGCTGGCGGAAGGCTTCGACGGTCGGG
CGCTCGACGAAATGGCACTGGATCGCGGCTGGCAGGCGCTGGCGCGGTTCGGCAAGAAGCTGCGCGGTTTCGAGCCCGGT
CGCGTGCGCGCAGTCGCGACCAGCGCGGTGCGCGAGGCCGACAATGCGCAGCTGTTCCTGGCCAGTGCGGAGCGGCATCT
GGGGTTTCGCATCGATGTGATTTCCGGGCATGAAGAAGCGCGTCTGGTCTACGCCGGTGTGGCCCACACCCTGCCGGTCG
CCGATGACATGCGTCTGGTGGTCGACATTGGCGGCGGCTCCACCGAGCTGATTCTCGGCCAGGGATCACAACCGCTCCTG
ACCGAAAGCATCGCCCTCGGCAGCGGCACCTTGAGCACCCGCTACTTTCGTAACGGTGAGATTTCCCCCGGCGCCCTGCA
AGAAGCCGAACGCGTAGCCATCCTGCAATTCGAAAAAGTCGCCCGCCGTTATCGCGCCCAGGGCTGGCAGCAGACCATCG
GCTCCTCGGGCACCGCGCGGATGCTCGCCAAAGTGCTCAAGGCCAATCGCCTGAACGATCATGGCGAGAGCGGCATCACC
TACGGCGGCCTGTTGCGGCTGTCGTTACGCCTGCTGGAAGTCAGCAATGTTCAACAGCTGAAACTGGCCGGCCTGCAACC
CCATCGCCAGAGCATCCTGCCCGGTGGTCTGGTGGTCATGCTGGCAGCATTCAAAGTATTCGGCATCTCGCAAATGGTGC
CGTCCGAACCCGGCTTGCGGCTGGGCGTGCTGCACGGTCTGATGAGCAACCACTGA

Upstream 100 bases:

>100_bases
CCGAACCGCCCTGCCCGCGTCATCAGGCTGTCATCGAACCCACGGCAGAATTCTCGCAAACCGTCCCGCGCCTCCCGACG
GATGATTTGCAAGGATCCCC

Downstream 100 bases:

>100_bases
GCGATTTCTGCTGCAGGATTTTCACTGCCGGATCAAGCGGTTCGTGATGGCGAAGACGCCCTTTCAATACTCGATGACGC
CTGCGTATAAACCCCTGCAA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKEDTSLFAAIDLGSNAFRMMIGQSVRSRKGFMIQEVKTLREPVRLAEGFDGRALDEMALDRGWQALARFGKKLRGFEPG
RVRAVATSAVREADNAQLFLASAERHLGFRIDVISGHEEARLVYAGVAHTLPVADDMRLVVDIGGGSTELILGQGSQPLL
TESIALGSGTLSTRYFRNGEISPGALQEAERVAILQFEKVARRYRAQGWQQTIGSSGTARMLAKVLKANRLNDHGESGIT
YGGLLRLSLRLLEVSNVQQLKLAGLQPHRQSILPGGLVVMLAAFKVFGISQMVPSEPGLRLGVLHGLMSNH

Sequences:

>Translated_311_residues
MKEDTSLFAAIDLGSNAFRMMIGQSVRSRKGFMIQEVKTLREPVRLAEGFDGRALDEMALDRGWQALARFGKKLRGFEPG
RVRAVATSAVREADNAQLFLASAERHLGFRIDVISGHEEARLVYAGVAHTLPVADDMRLVVDIGGGSTELILGQGSQPLL
TESIALGSGTLSTRYFRNGEISPGALQEAERVAILQFEKVARRYRAQGWQQTIGSSGTARMLAKVLKANRLNDHGESGIT
YGGLLRLSLRLLEVSNVQQLKLAGLQPHRQSILPGGLVVMLAAFKVFGISQMVPSEPGLRLGVLHGLMSNH
>Mature_311_residues
MKEDTSLFAAIDLGSNAFRMMIGQSVRSRKGFMIQEVKTLREPVRLAEGFDGRALDEMALDRGWQALARFGKKLRGFEPG
RVRAVATSAVREADNAQLFLASAERHLGFRIDVISGHEEARLVYAGVAHTLPVADDMRLVVDIGGGSTELILGQGSQPLL
TESIALGSGTLSTRYFRNGEISPGALQEAERVAILQFEKVARRYRAQGWQQTIGSSGTARMLAKVLKANRLNDHGESGIT
YGGLLRLSLRLLEVSNVQQLKLAGLQPHRQSILPGGLVVMLAAFKVFGISQMVPSEPGLRLGVLHGLMSNH

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=309, Percent_Identity=38.5113268608414, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1788848, Length=303, Percent_Identity=37.6237623762376, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 33812; Mature: 33812

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDTSLFAAIDLGSNAFRMMIGQSVRSRKGFMIQEVKTLREPVRLAEGFDGRALDEMAL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DRGWQALARFGKKLRGFEPGRVRAVATSAVREADNAQLFLASAERHLGFRIDVISGHEEA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCCCC
RLVYAGVAHTLPVADDMRLVVDIGGGSTELILGQGSQPLLTESIALGSGTLSTRYFRNGE
EEEEECHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCC
ISPGALQEAERVAILQFEKVARRYRAQGWQQTIGSSGTARMLAKVLKANRLNDHGESGIT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
YGGLLRLSLRLLEVSNVQQLKLAGLQPHRQSILPGGLVVMLAAFKVFGISQMVPSEPGLR
HHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
LGVLHGLMSNH
HHHHHHHHHCC
>Mature Secondary Structure
MKEDTSLFAAIDLGSNAFRMMIGQSVRSRKGFMIQEVKTLREPVRLAEGFDGRALDEMAL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DRGWQALARFGKKLRGFEPGRVRAVATSAVREADNAQLFLASAERHLGFRIDVISGHEEA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHCCCCEEEEEECCCCCC
RLVYAGVAHTLPVADDMRLVVDIGGGSTELILGQGSQPLLTESIALGSGTLSTRYFRNGE
EEEEECHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCC
ISPGALQEAERVAILQFEKVARRYRAQGWQQTIGSSGTARMLAKVLKANRLNDHGESGIT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
YGGLLRLSLRLLEVSNVQQLKLAGLQPHRQSILPGGLVVMLAAFKVFGISQMVPSEPGLR
HHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
LGVLHGLMSNH
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]