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The map label for this gene is ribB [H]

Identifier: 77459462

GI number: 77459462

Start: 3720705

End: 3721853

Strand: Direct

Name: ribB [H]

Synonym: Pfl01_3240

Alternate gene names: 77459462

Gene position: 3720705-3721853 (Clockwise)

Preceding gene: 77459459

Following gene: 77459463

Centisome position: 57.79

GC content: 61.01

Gene sequence:

>1149_bases
ATGGTATACCACAAATTTCATCCACATCGAGAGTCCAGCATGGCCTTCAACAGCATCGAAGAAATCATCGAAGATTATCG
CCTTGGCAAAATGGTGTTGCTGGTCGATGACGAGGATCGGGAAAACGAAGGTGACCTGCTGCTGGCCGCCGACCGTTGCA
CGCCCGAGGCAATCAGTTTCATGGCCCGTGAGGCTCGCGGTCTGATTTGTCTGACGTTGACTGACGATCATTGCCAGCGC
CTGGGGCTTGAGCAGATGGTGCCGAGCAATGGCAGCGTGTTCAGCACCGCGTTCACGGTCTCCATCGAAGCGGCGGTCGG
TGTGACTACTGGCATTTCTGCTGCCGACCGCGCCTGCACGGTGGCCGCGGCGGTGGCGCCAAATGCTCGCGCAGAAGACC
TGGTGCAGCCCGGTCATATCTTTCCGTTGCGCGCCAAGGAAGGTGGCGTGTTGACCCGTGCCGGTCACACCGAAGCCGGT
TGTGATCTGGCGCGGCTGGTGGGTTTCACGCCCGCCTCGGTGATTGTCGAGGTGATGAACGACGACGGCACCATGGCCCG
TCGTCCGGATCTGGAAGTCTTTGCGCACAAGCACGGGATCAAGATCGGCACCATCGCCGACCTGATCCACTATCGCCTGA
GCACCGAACACACCATAGAGCGCATCGGCGAACGGGAGTTGCCGACGGTGCATGGCACATTCCGTTTGATCACTTTCGAG
GACCGCATCGAAGGCGGCGTGCACATGGCGATGGTCATGGGTGAATTGCGCCGTGAGGAACCGACGCTGGTGCGCGTGCA
TGTGATCGATCCGTTGCGCGATCTGGTTGGCGCCGAGTACAGCGGGCCGACGAACTGGACGTTGTGGGCAGCGCTGCAAC
GGGTCGCGGCGGAGGGCCATGGCGTGGTCGTGGTGCTGGCCAATCATGAGTCGTCCCAGGCGTTGCTGGAGCGCATTCCG
CAACTGACTCAGCCGCCACGGCAGTTCAGTCGCTCGCAATCGCGGATCTATTCGGAGGTCGGCACCGGGGCGCAGATTCT
GCAGAACCTGGGCGTCGGCAAGCTACGCCACCTGGGCCCGCCGCTGAAATATGCTGGTTTGACCGGCTACGATCTGGAAG
TGGTCGAGAGCATTCCCTTCACCGAATAA

Upstream 100 bases:

>100_bases
GGCGCGCGCTGGGTGTATTGGCTGTAGTGATCGGGATCGGTGATGTCCACGTGTGCAATCCAGTACGCCTTCATAGTGAC
CTCTTGGTTGATTTTGTATT

Downstream 100 bases:

>100_bases
CCCCGTTTGCCAGATAGCCGGTACGGCAAAGTGCTTGCACAAAGTTTGGAATACCATAATATGATATTCCATAGACCGGA
CGATCTGAAAAACCGTCCAG

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MVYHKFHPHRESSMAFNSIEEIIEDYRLGKMVLLVDDEDRENEGDLLLAADRCTPEAISFMAREARGLICLTLTDDHCQR
LGLEQMVPSNGSVFSTAFTVSIEAAVGVTTGISAADRACTVAAAVAPNARAEDLVQPGHIFPLRAKEGGVLTRAGHTEAG
CDLARLVGFTPASVIVEVMNDDGTMARRPDLEVFAHKHGIKIGTIADLIHYRLSTEHTIERIGERELPTVHGTFRLITFE
DRIEGGVHMAMVMGELRREEPTLVRVHVIDPLRDLVGAEYSGPTNWTLWAALQRVAAEGHGVVVVLANHESSQALLERIP
QLTQPPRQFSRSQSRIYSEVGTGAQILQNLGVGKLRHLGPPLKYAGLTGYDLEVVESIPFTE

Sequences:

>Translated_382_residues
MVYHKFHPHRESSMAFNSIEEIIEDYRLGKMVLLVDDEDRENEGDLLLAADRCTPEAISFMAREARGLICLTLTDDHCQR
LGLEQMVPSNGSVFSTAFTVSIEAAVGVTTGISAADRACTVAAAVAPNARAEDLVQPGHIFPLRAKEGGVLTRAGHTEAG
CDLARLVGFTPASVIVEVMNDDGTMARRPDLEVFAHKHGIKIGTIADLIHYRLSTEHTIERIGERELPTVHGTFRLITFE
DRIEGGVHMAMVMGELRREEPTLVRVHVIDPLRDLVGAEYSGPTNWTLWAALQRVAAEGHGVVVVLANHESSQALLERIP
QLTQPPRQFSRSQSRIYSEVGTGAQILQNLGVGKLRHLGPPLKYAGLTGYDLEVVESIPFTE
>Mature_382_residues
MVYHKFHPHRESSMAFNSIEEIIEDYRLGKMVLLVDDEDRENEGDLLLAADRCTPEAISFMAREARGLICLTLTDDHCQR
LGLEQMVPSNGSVFSTAFTVSIEAAVGVTTGISAADRACTVAAAVAPNARAEDLVQPGHIFPLRAKEGGVLTRAGHTEAG
CDLARLVGFTPASVIVEVMNDDGTMARRPDLEVFAHKHGIKIGTIADLIHYRLSTEHTIERIGERELPTVHGTFRLITFE
DRIEGGVHMAMVMGELRREEPTLVRVHVIDPLRDLVGAEYSGPTNWTLWAALQRVAAEGHGVVVVLANHESSQALLERIP
QLTQPPRQFSRSQSRIYSEVGTGAQILQNLGVGKLRHLGPPLKYAGLTGYDLEVVESIPFTE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=51.7412935323383, Blast_Score=209, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=40.6862745098039, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 41893; Mature: 41893

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYHKFHPHRESSMAFNSIEEIIEDYRLGKMVLLVDDEDRENEGDLLLAADRCTPEAISF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHH
MAREARGLICLTLTDDHCQRLGLEQMVPSNGSVFSTAFTVSIEAAVGVTTGISAADRACT
HHHHCCCEEEEEECHHHHHHCCHHHHCCCCCCEEEEEEEEEEEEECCEECCCCHHHHHHE
VAAAVAPNARAEDLVQPGHIFPLRAKEGGVLTRAGHTEAGCDLARLVGFTPASVIVEVMN
EEEECCCCCCHHHHCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHCCCHHHHHEEEEC
DDGTMARRPDLEVFAHKHGIKIGTIADLIHYRLSTEHTIERIGERELPTVHGTFRLITFE
CCCCCCCCCCHHHHHHHCCCEEHHHHHHHHHHCCCHHHHHHCCCCCCCEECCEEEEEEEH
DRIEGGVHMAMVMGELRREEPTLVRVHVIDPLRDLVGAEYSGPTNWTLWAALQRVAAEGH
HHHCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
GVVVVLANHESSQALLERIPQLTQPPRQFSRSQSRIYSEVGTGAQILQNLGVGKLRHLGP
CEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCC
PLKYAGLTGYDLEVVESIPFTE
CCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MVYHKFHPHRESSMAFNSIEEIIEDYRLGKMVLLVDDEDRENEGDLLLAADRCTPEAISF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHH
MAREARGLICLTLTDDHCQRLGLEQMVPSNGSVFSTAFTVSIEAAVGVTTGISAADRACT
HHHHCCCEEEEEECHHHHHHCCHHHHCCCCCCEEEEEEEEEEEEECCEECCCCHHHHHHE
VAAAVAPNARAEDLVQPGHIFPLRAKEGGVLTRAGHTEAGCDLARLVGFTPASVIVEVMN
EEEECCCCCCHHHHCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHCCCHHHHHEEEEC
DDGTMARRPDLEVFAHKHGIKIGTIADLIHYRLSTEHTIERIGERELPTVHGTFRLITFE
CCCCCCCCCCHHHHHHHCCCEEHHHHHHHHHHCCCHHHHHHCCCCCCCEECCEEEEEEEH
DRIEGGVHMAMVMGELRREEPTLVRVHVIDPLRDLVGAEYSGPTNWTLWAALQRVAAEGH
HHHCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
GVVVVLANHESSQALLERIPQLTQPPRQFSRSQSRIYSEVGTGAQILQNLGVGKLRHLGP
CEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCC
PLKYAGLTGYDLEVVESIPFTE
CCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]