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The map label for this gene is potC [H]

Identifier: 77459366

GI number: 77459366

Start: 3609514

End: 3610302

Strand: Direct

Name: potC [H]

Synonym: Pfl01_3144

Alternate gene names: 77459366

Gene position: 3609514-3610302 (Clockwise)

Preceding gene: 77459365

Following gene: 77459367

Centisome position: 56.06

GC content: 60.96

Gene sequence:

>789_bases
ATGATCTCTTTGCACCTGAAAAAACTCCCGGCGACCCGGGAAATCAGCCTGCTGATCCTCGCTTATCTGTACGTGCCGAT
CCTGGTGTTGATCGCCTACAGCTTCAACGCCAACCGCTCGGCGACGGTGTGGACCGAGTTCTCGTTCGCCTGGTACGGGC
GGATCCTGGCCAATCCATCGATCCAGACCGCAGCGCTGAATTCGATCATCGTCGCGACCATCGCCACAGTCTGCGCCACG
ACCATTGCACTGCTCGCAGCCCTGGCGACTTACCGGCCGTTCTACGGACAGAAAATGGTCGAGGGCGGGATCAACCTGCC
GCTGATCCTGCCGGAGATCGTCACCGCCGTGGCCACCCTGCTGCTGTTCATGGCCCTGGGCATCAAGCTTGGGCTGATGA
CGGTGATCGTCGCGCACATTGGCTTCTGCATTCCGTTCGCCTACCTGCCGATCCGCGCACGGCTCAACGATCTGGACAAG
AGCCTGCTGGAGGCCGCCAACGATCTGTACGCCAACCCGTGGCAAGTGTTCCGCCGCGTGACCTTGCCGCTGTTGTGGCC
GGCGGTGCTGTCCGGTTCGGTGCTGGCGTTCGTGGTCAGCCTCGACGATTTCATCATGACCTTCTTCGTCGCCGGGCCCG
GTTCGACCACGTTGCCGGTGTACATCTTCTCGGCGATCAAGGCCGGCGTAACGCCCGAGATCAACGCGATTTCGACCCTG
ATGCTGGTGATTTCCATCGTGCTGGTGGTGCTGGCCTTCTGGCTTGGCCAACGCGGCAAACAACAATAA

Upstream 100 bases:

>100_bases
CGCTGTCGTTCCTGTTGCTGGGGATTCTGCTGTTGTCCCTGGTGCTCTACGCCCTCTACAGCCGCAGCGCGATGAAAAAC
CTGAACCGGGGAGCGAAAGC

Downstream 100 bases:

>100_bases
ACCTGGAGCGCGCTCATGAAAGTGAAAAACATGCGTCTGGCAGTATCCGGTCTGGCCCTGAGTTGTTTCACCGCGTTCGG
CGCCCACGCCGCCGAGCCCA

Product: binding-protein dependent transport system inner membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MISLHLKKLPATREISLLILAYLYVPILVLIAYSFNANRSATVWTEFSFAWYGRILANPSIQTAALNSIIVATIATVCAT
TIALLAALATYRPFYGQKMVEGGINLPLILPEIVTAVATLLLFMALGIKLGLMTVIVAHIGFCIPFAYLPIRARLNDLDK
SLLEAANDLYANPWQVFRRVTLPLLWPAVLSGSVLAFVVSLDDFIMTFFVAGPGSTTLPVYIFSAIKAGVTPEINAISTL
MLVISIVLVVLAFWLGQRGKQQ

Sequences:

>Translated_262_residues
MISLHLKKLPATREISLLILAYLYVPILVLIAYSFNANRSATVWTEFSFAWYGRILANPSIQTAALNSIIVATIATVCAT
TIALLAALATYRPFYGQKMVEGGINLPLILPEIVTAVATLLLFMALGIKLGLMTVIVAHIGFCIPFAYLPIRARLNDLDK
SLLEAANDLYANPWQVFRRVTLPLLWPAVLSGSVLAFVVSLDDFIMTFFVAGPGSTTLPVYIFSAIKAGVTPEINAISTL
MLVISIVLVVLAFWLGQRGKQQ
>Mature_262_residues
MISLHLKKLPATREISLLILAYLYVPILVLIAYSFNANRSATVWTEFSFAWYGRILANPSIQTAALNSIIVATIATVCAT
TIALLAALATYRPFYGQKMVEGGINLPLILPEIVTAVATLLLFMALGIKLGLMTVIVAHIGFCIPFAYLPIRARLNDLDK
SLLEAANDLYANPWQVFRRVTLPLLWPAVLSGSVLAFVVSLDDFIMTFFVAGPGSTTLPVYIFSAIKAGVTPEINAISTL
MLVISIVLVVLAFWLGQRGKQQ

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=218, Percent_Identity=41.2844036697248, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787081, Length=270, Percent_Identity=38.5185185185185, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1787714, Length=249, Percent_Identity=34.136546184739, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788764, Length=181, Percent_Identity=29.8342541436464, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787713, Length=71, Percent_Identity=46.4788732394366, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28559; Mature: 28559

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLHLKKLPATREISLLILAYLYVPILVLIAYSFNANRSATVWTEFSFAWYGRILANPS
CCEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCC
IQTAALNSIIVATIATVCATTIALLAALATYRPFYGQKMVEGGINLPLILPEIVTAVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LLFMALGIKLGLMTVIVAHIGFCIPFAYLPIRARLNDLDKSLLEAANDLYANPWQVFRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLPLLWPAVLSGSVLAFVVSLDDFIMTFFVAGPGSTTLPVYIFSAIKAGVTPEINAISTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
MLVISIVLVVLAFWLGQRGKQQ
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MISLHLKKLPATREISLLILAYLYVPILVLIAYSFNANRSATVWTEFSFAWYGRILANPS
CCEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCC
IQTAALNSIIVATIATVCATTIALLAALATYRPFYGQKMVEGGINLPLILPEIVTAVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LLFMALGIKLGLMTVIVAHIGFCIPFAYLPIRARLNDLDKSLLEAANDLYANPWQVFRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLPLLWPAVLSGSVLAFVVSLDDFIMTFFVAGPGSTTLPVYIFSAIKAGVTPEINAISTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
MLVISIVLVVLAFWLGQRGKQQ
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]