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The map label for this gene is zraS [C]

Identifier: 77459362

GI number: 77459362

Start: 3604439

End: 3606550

Strand: Reverse

Name: zraS [C]

Synonym: Pfl01_3140

Alternate gene names: 77459362

Gene position: 3606550-3604439 (Counterclockwise)

Preceding gene: 77459363

Following gene: 77459361

Centisome position: 56.02

GC content: 62.78

Gene sequence:

>2112_bases
ATGCAGTTTTTATCCGATAGCCATGGGTGTGACGGCTGGCAAGGCGAGATGGCCGGGCGAATCCGTGCGTTCGACTGGAG
CAGGACCGATCTGGGCCCGCTCGAAACCTGGCCGGCCAGCCTGTGCAGCACAGTGCAACTGATGCTGGCATCGCCGCTGC
CGATGGTCATGCTCTGGGGCCATGCCGGTTACATGATCTACAACGATGCTTACTCACGATTCGCCGGCGGACGACATCCC
TACCTGCTCGGATCGCCGGTGGAACTGGGCTGGCCGGAGGTGGCCGATTTCAACCGGCATGTGGTCGACACCTGTCTGGC
CGGCGGCACCCTGGAATATCGCAACAAGGTCCTGGTGTTGCTGCGCGACGGCGTACCCGAGGATGTCTGGCTCGATTTGT
ATTACAGCCCGGTGGCCAACGATGCCGGTGTGCCTTCGGGCGTCATGGCGATGGTGGTGGAAACCACTGAACTGGTGTTG
TCCGAACGCTTGCGTCAGGCCGCCGAAGACGCTTATCGCGCCGATAACGAGCGGGTGCGACTGGCACTGAATGCCGGGGC
ACTGCTTGGCTCGTTTGTCTGGGACGTCAGAAACAATGTGCTGTCGGCCGATGAGCGATTTGCCCGCACATTTTCCTTTC
CGCCGGATCAGGACCTGACCAACCTGCCGCAGCACATTACCGAGGCGCACATTCATCCCGACGACCGCAGTTGGGTGCAG
GAATGCGTCGAGAATGCGGTGCGCACCGGCGAGCCGTACAACGCCGAATACCGCGTGATACGCGCTGATGGCAGTTTCCT
CTGGGTGCTGGCCAGCGGTTGCTGCGAGTTCGACGAGCAGGGACAGCCGTTCCGTTTTCCCGGCGTGCTGATCGACATCC
ACGAGCGCAAGATCGCCGAAGAGTCCCTGCTCAAATTCACCCGCAATCTCGAACAACGGGTGGCTGATGAAGTCGGCGCG
CGTCTCTCCGCCGAAGAGCAACTGCGCCAGTCGCAGAAACTCGAATCCATCGGCGGCCTCACCGGCGGCGTGGCTCACGA
CTTCAACAACCTGCTGCAAGTGATCGCCGGCAACCTGCACCTGCTGGCGCGACATGAACCGAACAACGCCAACGTCCAGC
GCCGGGTCAGCGCCTCGCTGGCAGCGGTGGAACGTGGCGCCAAGCTGTCCTCGCAACTGCTCGCGTTTGCCCGTCGCCAG
CCGCTGTCGCCGGCGGTGTGCAATCCCCGCCAGATCTTCGAAGGCGTCGGCGAGTTGCTGCAACGGGCACTGGGCGAAAC
CATTCAGATCGACGTGCAGCTGCCGGAAGATCCGTGGCACATCAACGTCGACCGCAATCAACTGGAAAACGCCATTCTCA
ATCTGGCGATCAATGCCCGGGACGCCATGAAGGGCGAGGGCACCATTGTGCTCGGTGCCTCGAATCTCTCACTGGATCGG
GCGTTCTGCTCGGGCAAGGGCATCGTGCCGGGGGATTTCGTCCGGGTTTCGGTCAGTGACAGCGGCGTCGGCATTGCCCC
GCACATACTCGAGCAGGTGTTCGAACCGTTCTTCACCACCAAGGCCGACGGCCAGGGCACCGGCCTGGGCTTGAGCATGG
TGTTCGGCTTCGTCAAACAGAGCGGCGGGCATGTCGAGATCGACAGCCAGGTGGGCCAGGGCACGCGCGTGCAGTTGTAC
TTTCCGCGCAGCCTGCGAGCGGTGGGTCAAGCGGCGCCAAGCGTGGAGACCCCCCTCACGGGCGGCCACGAGACAATCCT
GGTGGTCGAGGACAACGAAGCGGTGCGCACCTCGGCAGTTGAACTACTGCGCGAGGAAGGTTATCGCGTGCTGACCGCCG
GTAATGGTGACGCAGCCATGCAGATGTTGATGGAAGGCGCTCGGGTCGACCTGATCTTCACCGACGTGGTCATGCCCGGT
CTTATCAAGAGCTCCGATCTGGCGGCGTGGGCCAAGGTGCAAATGCCGCCGGTGGCCGTGCTGTTCACCTCGGGCCACAC
CCGCGACATCATCTCGCGCAACCACCAGCTAAGCCCCGACACCCATTTGCTCGGCAAGCCCTATGGCCCCGAAGCGCTGC
TGCAGATGATCCGTTCCGTGCTCAGCACCTGA

Upstream 100 bases:

>100_bases
TAATGAAACCATCGTTGCCCGATGCGCTCGAAACAGACGGGCGCGACGTTTGACCGCGCAGCGATAGATCCGGATCAACC
ACAAGGCGTTGAAGCAGCTG

Downstream 100 bases:

>100_bases
GCTCCAATCCCTTGACCAAGGCTGGCCGATGACTTCCAGGCGCAATTCCAGTTCTGCCGCCGGCATGGTTCGCGTGCGCG
GTGCCCGTGAACACAACCTG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MQFLSDSHGCDGWQGEMAGRIRAFDWSRTDLGPLETWPASLCSTVQLMLASPLPMVMLWGHAGYMIYNDAYSRFAGGRHP
YLLGSPVELGWPEVADFNRHVVDTCLAGGTLEYRNKVLVLLRDGVPEDVWLDLYYSPVANDAGVPSGVMAMVVETTELVL
SERLRQAAEDAYRADNERVRLALNAGALLGSFVWDVRNNVLSADERFARTFSFPPDQDLTNLPQHITEAHIHPDDRSWVQ
ECVENAVRTGEPYNAEYRVIRADGSFLWVLASGCCEFDEQGQPFRFPGVLIDIHERKIAEESLLKFTRNLEQRVADEVGA
RLSAEEQLRQSQKLESIGGLTGGVAHDFNNLLQVIAGNLHLLARHEPNNANVQRRVSASLAAVERGAKLSSQLLAFARRQ
PLSPAVCNPRQIFEGVGELLQRALGETIQIDVQLPEDPWHINVDRNQLENAILNLAINARDAMKGEGTIVLGASNLSLDR
AFCSGKGIVPGDFVRVSVSDSGVGIAPHILEQVFEPFFTTKADGQGTGLGLSMVFGFVKQSGGHVEIDSQVGQGTRVQLY
FPRSLRAVGQAAPSVETPLTGGHETILVVEDNEAVRTSAVELLREEGYRVLTAGNGDAAMQMLMEGARVDLIFTDVVMPG
LIKSSDLAAWAKVQMPPVAVLFTSGHTRDIISRNHQLSPDTHLLGKPYGPEALLQMIRSVLST

Sequences:

>Translated_703_residues
MQFLSDSHGCDGWQGEMAGRIRAFDWSRTDLGPLETWPASLCSTVQLMLASPLPMVMLWGHAGYMIYNDAYSRFAGGRHP
YLLGSPVELGWPEVADFNRHVVDTCLAGGTLEYRNKVLVLLRDGVPEDVWLDLYYSPVANDAGVPSGVMAMVVETTELVL
SERLRQAAEDAYRADNERVRLALNAGALLGSFVWDVRNNVLSADERFARTFSFPPDQDLTNLPQHITEAHIHPDDRSWVQ
ECVENAVRTGEPYNAEYRVIRADGSFLWVLASGCCEFDEQGQPFRFPGVLIDIHERKIAEESLLKFTRNLEQRVADEVGA
RLSAEEQLRQSQKLESIGGLTGGVAHDFNNLLQVIAGNLHLLARHEPNNANVQRRVSASLAAVERGAKLSSQLLAFARRQ
PLSPAVCNPRQIFEGVGELLQRALGETIQIDVQLPEDPWHINVDRNQLENAILNLAINARDAMKGEGTIVLGASNLSLDR
AFCSGKGIVPGDFVRVSVSDSGVGIAPHILEQVFEPFFTTKADGQGTGLGLSMVFGFVKQSGGHVEIDSQVGQGTRVQLY
FPRSLRAVGQAAPSVETPLTGGHETILVVEDNEAVRTSAVELLREEGYRVLTAGNGDAAMQMLMEGARVDLIFTDVVMPG
LIKSSDLAAWAKVQMPPVAVLFTSGHTRDIISRNHQLSPDTHLLGKPYGPEALLQMIRSVLST
>Mature_703_residues
MQFLSDSHGCDGWQGEMAGRIRAFDWSRTDLGPLETWPASLCSTVQLMLASPLPMVMLWGHAGYMIYNDAYSRFAGGRHP
YLLGSPVELGWPEVADFNRHVVDTCLAGGTLEYRNKVLVLLRDGVPEDVWLDLYYSPVANDAGVPSGVMAMVVETTELVL
SERLRQAAEDAYRADNERVRLALNAGALLGSFVWDVRNNVLSADERFARTFSFPPDQDLTNLPQHITEAHIHPDDRSWVQ
ECVENAVRTGEPYNAEYRVIRADGSFLWVLASGCCEFDEQGQPFRFPGVLIDIHERKIAEESLLKFTRNLEQRVADEVGA
RLSAEEQLRQSQKLESIGGLTGGVAHDFNNLLQVIAGNLHLLARHEPNNANVQRRVSASLAAVERGAKLSSQLLAFARRQ
PLSPAVCNPRQIFEGVGELLQRALGETIQIDVQLPEDPWHINVDRNQLENAILNLAINARDAMKGEGTIVLGASNLSLDR
AFCSGKGIVPGDFVRVSVSDSGVGIAPHILEQVFEPFFTTKADGQGTGLGLSMVFGFVKQSGGHVEIDSQVGQGTRVQLY
FPRSLRAVGQAAPSVETPLTGGHETILVVEDNEAVRTSAVELLREEGYRVLTAGNGDAAMQMLMEGARVDLIFTDVVMPG
LIKSSDLAAWAKVQMPPVAVLFTSGHTRDIISRNHQLSPDTHLLGKPYGPEALLQMIRSVLST

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=30.9623430962343, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI145693157, Length=287, Percent_Identity=27.1777003484321, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=459, Percent_Identity=23.9651416122004, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788381, Length=259, Percent_Identity=23.5521235521236, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.1082251082251, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=26.4227642276423, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77057; Mature: 77057

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLSDSHGCDGWQGEMAGRIRAFDWSRTDLGPLETWPASLCSTVQLMLASPLPMVMLWG
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
HAGYMIYNDAYSRFAGGRHPYLLGSPVELGWPEVADFNRHVVDTCLAGGTLEYRNKVLVL
CCCEEEECCHHHHHCCCCCCEEECCCCCCCCCCHHHCHHHHHHHHHCCCEEECCCEEEEE
LRDGVPEDVWLDLYYSPVANDAGVPSGVMAMVVETTELVLSERLRQAAEDAYRADNERVR
EECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LALNAGALLGSFVWDVRNNVLSADERFARTFSFPPDQDLTNLPQHITEAHIHPDDRSWVQ
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
ECVENAVRTGEPYNAEYRVIRADGSFLWVLASGCCEFDEQGQPFRFPGVLIDIHERKIAE
HHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEECCCEEEEEHHHHHHH
ESLLKFTRNLEQRVADEVGARLSAEEQLRQSQKLESIGGLTGGVAHDFNNLLQVIAGNLH
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEE
LLARHEPNNANVQRRVSASLAAVERGAKLSSQLLAFARRQPLSPAVCNPRQIFEGVGELL
EEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QRALGETIQIDVQLPEDPWHINVDRNQLENAILNLAINARDAMKGEGTIVLGASNLSLDR
HHHCCCEEEEEEECCCCCEEEECCHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHH
AFCSGKGIVPGDFVRVSVSDSGVGIAPHILEQVFEPFFTTKADGQGTGLGLSMVFGFVKQ
HHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
SGGHVEIDSQVGQGTRVQLYFPRSLRAVGQAAPSVETPLTGGHETILVVEDNEAVRTSAV
CCCEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHH
ELLREEGYRVLTAGNGDAAMQMLMEGARVDLIFTDVVMPGLIKSSDLAAWAKVQMPPVAV
HHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCCHHEEECCCCEEE
LFTSGHTRDIISRNHQLSPDTHLLGKPYGPEALLQMIRSVLST
EEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFLSDSHGCDGWQGEMAGRIRAFDWSRTDLGPLETWPASLCSTVQLMLASPLPMVMLWG
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
HAGYMIYNDAYSRFAGGRHPYLLGSPVELGWPEVADFNRHVVDTCLAGGTLEYRNKVLVL
CCCEEEECCHHHHHCCCCCCEEECCCCCCCCCCHHHCHHHHHHHHHCCCEEECCCEEEEE
LRDGVPEDVWLDLYYSPVANDAGVPSGVMAMVVETTELVLSERLRQAAEDAYRADNERVR
EECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LALNAGALLGSFVWDVRNNVLSADERFARTFSFPPDQDLTNLPQHITEAHIHPDDRSWVQ
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
ECVENAVRTGEPYNAEYRVIRADGSFLWVLASGCCEFDEQGQPFRFPGVLIDIHERKIAE
HHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCEECCCEEEEEHHHHHHH
ESLLKFTRNLEQRVADEVGARLSAEEQLRQSQKLESIGGLTGGVAHDFNNLLQVIAGNLH
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEE
LLARHEPNNANVQRRVSASLAAVERGAKLSSQLLAFARRQPLSPAVCNPRQIFEGVGELL
EEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QRALGETIQIDVQLPEDPWHINVDRNQLENAILNLAINARDAMKGEGTIVLGASNLSLDR
HHHCCCEEEEEEECCCCCEEEECCHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCHHH
AFCSGKGIVPGDFVRVSVSDSGVGIAPHILEQVFEPFFTTKADGQGTGLGLSMVFGFVKQ
HHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
SGGHVEIDSQVGQGTRVQLYFPRSLRAVGQAAPSVETPLTGGHETILVVEDNEAVRTSAV
CCCEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHH
ELLREEGYRVLTAGNGDAAMQMLMEGARVDLIFTDVVMPGLIKSSDLAAWAKVQMPPVAV
HHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCCHHEEECCCCEEE
LFTSGHTRDIISRNHQLSPDTHLLGKPYGPEALLQMIRSVLST
EEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA