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The map label for this gene is uvrA [H]

Identifier: 77459361

GI number: 77459361

Start: 3601777

End: 3604410

Strand: Reverse

Name: uvrA [H]

Synonym: Pfl01_3139

Alternate gene names: 77459361

Gene position: 3604410-3601777 (Counterclockwise)

Preceding gene: 77459362

Following gene: 77459353

Centisome position: 55.98

GC content: 64.65

Gene sequence:

>2634_bases
ATGACTTCCAGGCGCAATTCCAGTTCTGCCGCCGGCATGGTTCGCGTGCGCGGTGCCCGTGAACACAACCTGAAGAACGT
GGACGTCGACATTCCTCGCGATGCACTGGTGGTGTTCACCGGGGTGTCGGGCTCGGGCAAGTCGTCGCTGGCGTTTTCGA
CGCTGTATGCCGAAGCCCAGCGACGCTATTTCGAATCGGTGGCGCCCTATGCGCGGCGGCTGATCGATCAGGTCGGCGTG
CCGGACGTCGATTCCATCGAAGGCCTGCCGCCGGCCGTGGCCCTGCAGCAGCAGCGCGGCACGCCGAGCACGCGTTCGTC
GGTGGGCAGCGTCACCACGTTGTCGAGCCTGATCCGCATGCTGTACTCGCGCGCCGGCAGCTACCCACCGGGTCAGCCGA
TGCTGTATGCCGAAGATTTTTCACCGAACACGCCGCAAGGCGCGTGCCCGCAATGCCATGGACTGGGCCGGGTCTACGAG
GTCACCGAGGCGTTGATGGTGCCGGATCCGAATCTGACCATCCGCCAGCGCGCCGTAGCGTCATGGCCGCTGGCCTGGCA
GGGGCAGAACCTGCGCGACATCCTGGTGACCATGGGTATCGATGTCGATATCCCGTGGCGCAAGCTGCCGAAAAAACAGC
GTGACTGGATCCTCTTCACCGAGGAAACACCAACCGTTCCGGTGTACGCCGGGCTGACGCCGGAAGAAACCCGCGTCGCC
CTCAAGCGCAACATGGAGCCCAGTTATCAAGGCACCTTCACTGGCGCCCGGCGCTACATCCTGCATACCTTCACCCATTC
GCAAAGTGCGCTGATGAAGAAGCGCGTGTCGCAGTTCATGATCGGCAGCCTTTGCCCGTTGTGCGATGGCAAGCGCCTCA
AGCGTGAGGCGCTGTCGGTAACGTTTGCCGGGCATGACATCGGCGAGTTGTCGCGGATGTCTCTGTTGCAAGTCGCCGAG
GTTTTGCGGCCGGTCGCGGACGCGAGCTGGCTGGAACACGCCGATGAAACCGGTGAAACCCTGACCCACAGCCAGACCCG
CGAAGCCCGGCAGCAGCGCGTGGCCCATGGCGCCAGCGGCCACGCCAATGCGCCGGACGTGCGCCATACGCCGAACCTGT
CGCTGGAAAAACGCCTGGCCGCGCAGCGCATTGCCGAGGATCTGCTGGAACGGGTCAGCACCCTGACCGATCTGGGCCTC
GGTTATCTGGCCCTGGAACGAAGCACGCCGACCCTGTCGTCCGGCGAATTGCAACGCCTGCGACTGGCCACCCAACTGGG
CTCGCAACTGTTTGGCGTGATCTACGTGCTCGACGAACCTTCCGCCGGCCTGCACCCGGCTGACGGCGAGGCCCTGTTCG
AAGCGTTGCAGCGACTGAAGGCCGACGGCAACAGCGTGTTTGTGGTCGAGCACGATCTGGACACCATGCGCCGGGCCGAC
TGGCTGATCGACGTCGGCCCGGCAGCCGGTGAAAAGGGCGGGCAGATTCTCTACAGCGGCCCGCCGCCGGGGCTGGCGGC
GATCGAACACTCGCAGACCCGCGCCTACCTGTTCGCCGAACAGCAACGGTCGACCCGTGCCGCGCGCAAGCCTTCTGGGT
GGCTGAAGCTAGATGGCGTCACCCGCAACAACCTCAATAACCTCAGCGCCGAATTTCCGTTGGGTTGCTTTACCTCGGTC
ACCGGTGTCTCCGGTTCCGGCAAGTCGAGCCTGGTCAGCCAGGCGCTGCTGGAACTGGTCGGCGCGCAGCTTGGGCGCAG
CGTCAGTGACGCCGAGCCGGAAGAGCTCAATCTGGAAGACGATACCCCGTCTGCCAGCACCGGCCAGGTCAGCGCCGGGC
TGGAGTCGATCAAGCGTCTGGTTCAGGTCGATCAGAAACCCATCGGCCGCACCCCGCGTTCGAATCTGGCGACCTACACC
GGGCTGTTCGACAACGTGCGCAAGTTGTTTGCCGCAACCAGCGAAGCGAAAGCGGCGGGTTACGACGCCGGACAGTTTTC
CTTCAACGTCGCCAAGGGGCGCTGCCCGACCTGCGAAGGCGAGGGGTTTGTCAGTGTCGAGTTGCTGTTCATGCCCAGCG
TTTATGCGCCGTGCCCGACCTGTCACGGCGCGCGTTACAACCCCGAGACCCTGGCCATCCTCTGGCAGGGCTTGAGCATT
GCGCAGGTGCTGCAATTGACCGTGGATGAAGCGGTGGCGGTATTTGCCGAGCAACCGGCGATCCGTCGTTCACTGGAAGT
GCTGCGCGACATCGGCCTCGGTTACCTGCGCCTCGGGCAACCGGCGACCGAGTTGTCCGGCGGCGAAGCCCAGCGGATCA
AACTGGCCACCGAGCTGCAACGCAATCAGCGCGGCGCGACGTTGTATGTGCTAGACGAGCCTACCACCGGCTTGCATCCG
CGAGACGTCGACCGCTTGCTGGAGCAACTGGAAAATCTGGTGAACGCAGGACACACGGTGATCGTGGTCGAGCATGAAAT
GCGCGTGGTGGCGCAGAGTGACTGGGTGATCGACATCGGCCCGGGTGCGGGGGATCAGGGCGGCCGGATCGTCGTGGCCG
GGACGCCGCAGAAAGTGGCGGCGAGCAAGAAGAGCCGGACTGCGCCGTTTCTCGCCCGCGCCCTCAGCCGCTAG

Upstream 100 bases:

>100_bases
ACCCATTTGCTCGGCAAGCCCTATGGCCCCGAAGCGCTGCTGCAGATGATCCGTTCCGTGCTCAGCACCTGAGCTCCAAT
CCCTTGACCAAGGCTGGCCG

Downstream 100 bases:

>100_bases
GTGCATCAGGCACCGTCGAGCGTGCGACGCACCTTGTCCAGCAATGCGCTGATCTGAAACGGTTTGACCAGCATGTCCAT
ACCCGCCCCGAGGAACACCT

Product: excinuclease ABC subunit A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 877; Mature: 876

Protein sequence:

>877_residues
MTSRRNSSSAAGMVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFSTLYAEAQRRYFESVAPYARRLIDQVGV
PDVDSIEGLPPAVALQQQRGTPSTRSSVGSVTTLSSLIRMLYSRAGSYPPGQPMLYAEDFSPNTPQGACPQCHGLGRVYE
VTEALMVPDPNLTIRQRAVASWPLAWQGQNLRDILVTMGIDVDIPWRKLPKKQRDWILFTEETPTVPVYAGLTPEETRVA
LKRNMEPSYQGTFTGARRYILHTFTHSQSALMKKRVSQFMIGSLCPLCDGKRLKREALSVTFAGHDIGELSRMSLLQVAE
VLRPVADASWLEHADETGETLTHSQTREARQQRVAHGASGHANAPDVRHTPNLSLEKRLAAQRIAEDLLERVSTLTDLGL
GYLALERSTPTLSSGELQRLRLATQLGSQLFGVIYVLDEPSAGLHPADGEALFEALQRLKADGNSVFVVEHDLDTMRRAD
WLIDVGPAAGEKGGQILYSGPPPGLAAIEHSQTRAYLFAEQQRSTRAARKPSGWLKLDGVTRNNLNNLSAEFPLGCFTSV
TGVSGSGKSSLVSQALLELVGAQLGRSVSDAEPEELNLEDDTPSASTGQVSAGLESIKRLVQVDQKPIGRTPRSNLATYT
GLFDNVRKLFAATSEAKAAGYDAGQFSFNVAKGRCPTCEGEGFVSVELLFMPSVYAPCPTCHGARYNPETLAILWQGLSI
AQVLQLTVDEAVAVFAEQPAIRRSLEVLRDIGLGYLRLGQPATELSGGEAQRIKLATELQRNQRGATLYVLDEPTTGLHP
RDVDRLLEQLENLVNAGHTVIVVEHEMRVVAQSDWVIDIGPGAGDQGGRIVVAGTPQKVAASKKSRTAPFLARALSR

Sequences:

>Translated_877_residues
MTSRRNSSSAAGMVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFSTLYAEAQRRYFESVAPYARRLIDQVGV
PDVDSIEGLPPAVALQQQRGTPSTRSSVGSVTTLSSLIRMLYSRAGSYPPGQPMLYAEDFSPNTPQGACPQCHGLGRVYE
VTEALMVPDPNLTIRQRAVASWPLAWQGQNLRDILVTMGIDVDIPWRKLPKKQRDWILFTEETPTVPVYAGLTPEETRVA
LKRNMEPSYQGTFTGARRYILHTFTHSQSALMKKRVSQFMIGSLCPLCDGKRLKREALSVTFAGHDIGELSRMSLLQVAE
VLRPVADASWLEHADETGETLTHSQTREARQQRVAHGASGHANAPDVRHTPNLSLEKRLAAQRIAEDLLERVSTLTDLGL
GYLALERSTPTLSSGELQRLRLATQLGSQLFGVIYVLDEPSAGLHPADGEALFEALQRLKADGNSVFVVEHDLDTMRRAD
WLIDVGPAAGEKGGQILYSGPPPGLAAIEHSQTRAYLFAEQQRSTRAARKPSGWLKLDGVTRNNLNNLSAEFPLGCFTSV
TGVSGSGKSSLVSQALLELVGAQLGRSVSDAEPEELNLEDDTPSASTGQVSAGLESIKRLVQVDQKPIGRTPRSNLATYT
GLFDNVRKLFAATSEAKAAGYDAGQFSFNVAKGRCPTCEGEGFVSVELLFMPSVYAPCPTCHGARYNPETLAILWQGLSI
AQVLQLTVDEAVAVFAEQPAIRRSLEVLRDIGLGYLRLGQPATELSGGEAQRIKLATELQRNQRGATLYVLDEPTTGLHP
RDVDRLLEQLENLVNAGHTVIVVEHEMRVVAQSDWVIDIGPGAGDQGGRIVVAGTPQKVAASKKSRTAPFLARALSR
>Mature_876_residues
TSRRNSSSAAGMVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFSTLYAEAQRRYFESVAPYARRLIDQVGVP
DVDSIEGLPPAVALQQQRGTPSTRSSVGSVTTLSSLIRMLYSRAGSYPPGQPMLYAEDFSPNTPQGACPQCHGLGRVYEV
TEALMVPDPNLTIRQRAVASWPLAWQGQNLRDILVTMGIDVDIPWRKLPKKQRDWILFTEETPTVPVYAGLTPEETRVAL
KRNMEPSYQGTFTGARRYILHTFTHSQSALMKKRVSQFMIGSLCPLCDGKRLKREALSVTFAGHDIGELSRMSLLQVAEV
LRPVADASWLEHADETGETLTHSQTREARQQRVAHGASGHANAPDVRHTPNLSLEKRLAAQRIAEDLLERVSTLTDLGLG
YLALERSTPTLSSGELQRLRLATQLGSQLFGVIYVLDEPSAGLHPADGEALFEALQRLKADGNSVFVVEHDLDTMRRADW
LIDVGPAAGEKGGQILYSGPPPGLAAIEHSQTRAYLFAEQQRSTRAARKPSGWLKLDGVTRNNLNNLSAEFPLGCFTSVT
GVSGSGKSSLVSQALLELVGAQLGRSVSDAEPEELNLEDDTPSASTGQVSAGLESIKRLVQVDQKPIGRTPRSNLATYTG
LFDNVRKLFAATSEAKAAGYDAGQFSFNVAKGRCPTCEGEGFVSVELLFMPSVYAPCPTCHGARYNPETLAILWQGLSIA
QVLQLTVDEAVAVFAEQPAIRRSLEVLRDIGLGYLRLGQPATELSGGEAQRIKLATELQRNQRGATLYVLDEPTTGLHPR
DVDRLLEQLENLVNAGHTVIVVEHEMRVVAQSDWVIDIGPGAGDQGGRIVVAGTPQKVAASKKSRTAPFLARALSR

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=740, Percent_Identity=38.1081081081081, Blast_Score=483, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017871 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 95228; Mature: 95097

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRRNSSSAAGMVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFSTLYAEAQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RRYFESVAPYARRLIDQVGVPDVDSIEGLPPAVALQQQRGTPSTRSSVGSVTTLSSLIRM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHCHHHHHHHHHHH
LYSRAGSYPPGQPMLYAEDFSPNTPQGACPQCHGLGRVYEVTEALMVPDPNLTIRQRAVA
HHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCHHHHHHHH
SWPLAWQGQNLRDILVTMGIDVDIPWRKLPKKQRDWILFTEETPTVPVYAGLTPEETRVA
CCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCCEEEEECCCCHHHHHH
LKRNMEPSYQGTFTGARRYILHTFTHSQSALMKKRVSQFMIGSLCPLCDGKRLKREALSV
HHHCCCCCCCCCHHHHHEEEHEEHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEE
TFAGHDIGELSRMSLLQVAEVLRPVADASWLEHADETGETLTHSQTREARQQRVAHGASG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
HANAPDVRHTPNLSLEKRLAAQRIAEDLLERVSTLTDLGLGYLALERSTPTLSSGELQRL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
RLATQLGSQLFGVIYVLDEPSAGLHPADGEALFEALQRLKADGNSVFVVEHDLDTMRRAD
HHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHC
WLIDVGPAAGEKGGQILYSGPPPGLAAIEHSQTRAYLFAEQQRSTRAARKPSGWLKLDGV
CEEECCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEHHHHHHHHHCCCCCCEEECCC
TRNNLNNLSAEFPLGCFTSVTGVSGSGKSSLVSQALLELVGAQLGRSVSDAEPEELNLED
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DTPSASTGQVSAGLESIKRLVQVDQKPIGRTPRSNLATYTGLFDNVRKLFAATSEAKAAG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCC
YDAGQFSFNVAKGRCPTCEGEGFVSVELLFMPSVYAPCPTCHGARYNPETLAILWQGLSI
CCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCH
AQVLQLTVDEAVAVFAEQPAIRRSLEVLRDIGLGYLRLGQPATELSGGEAQRIKLATELQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCHHHCCCCCHHHHHHHHHHH
RNQRGATLYVLDEPTTGLHPRDVDRLLEQLENLVNAGHTVIVVEHEMRVVAQSDWVIDIG
HCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEECC
PGAGDQGGRIVVAGTPQKVAASKKSRTAPFLARALSR
CCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TSRRNSSSAAGMVRVRGAREHNLKNVDVDIPRDALVVFTGVSGSGKSSLAFSTLYAEAQ
CCCCCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHHHH
RRYFESVAPYARRLIDQVGVPDVDSIEGLPPAVALQQQRGTPSTRSSVGSVTTLSSLIRM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHCHHHHHHHHHHH
LYSRAGSYPPGQPMLYAEDFSPNTPQGACPQCHGLGRVYEVTEALMVPDPNLTIRQRAVA
HHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCHHHHHHHH
SWPLAWQGQNLRDILVTMGIDVDIPWRKLPKKQRDWILFTEETPTVPVYAGLTPEETRVA
CCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCCEEEEECCCCHHHHHH
LKRNMEPSYQGTFTGARRYILHTFTHSQSALMKKRVSQFMIGSLCPLCDGKRLKREALSV
HHHCCCCCCCCCHHHHHEEEHEEHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEE
TFAGHDIGELSRMSLLQVAEVLRPVADASWLEHADETGETLTHSQTREARQQRVAHGASG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
HANAPDVRHTPNLSLEKRLAAQRIAEDLLERVSTLTDLGLGYLALERSTPTLSSGELQRL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
RLATQLGSQLFGVIYVLDEPSAGLHPADGEALFEALQRLKADGNSVFVVEHDLDTMRRAD
HHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHC
WLIDVGPAAGEKGGQILYSGPPPGLAAIEHSQTRAYLFAEQQRSTRAARKPSGWLKLDGV
CEEECCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEHHHHHHHHHCCCCCCEEECCC
TRNNLNNLSAEFPLGCFTSVTGVSGSGKSSLVSQALLELVGAQLGRSVSDAEPEELNLED
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DTPSASTGQVSAGLESIKRLVQVDQKPIGRTPRSNLATYTGLFDNVRKLFAATSEAKAAG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCC
YDAGQFSFNVAKGRCPTCEGEGFVSVELLFMPSVYAPCPTCHGARYNPETLAILWQGLSI
CCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCH
AQVLQLTVDEAVAVFAEQPAIRRSLEVLRDIGLGYLRLGQPATELSGGEAQRIKLATELQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCHHHCCCCCHHHHHHHHHHH
RNQRGATLYVLDEPTTGLHPRDVDRLLEQLENLVNAGHTVIVVEHEMRVVAQSDWVIDIG
HCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEECC
PGAGDQGGRIVVAGTPQKVAASKKSRTAPFLARALSR
CCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8269961 [H]