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The map label for this gene is arcB [C]

Identifier: 77459360

GI number: 77459360

Start: 3599828

End: 3601771

Strand: Direct

Name: arcB [C]

Synonym: Pfl01_3138

Alternate gene names: 77459360

Gene position: 3599828-3601771 (Clockwise)

Preceding gene: 77459359

Following gene: 77459364

Centisome position: 55.91

GC content: 63.17

Gene sequence:

>1944_bases
ATGAAACATGACATCCGTCTGTTGATCGTCGATGACAACGTCGCCACTCGCTATGCCTTGCGCCGACGACTGGAGCGCCA
CGGTTACGAAGTGCTCGAGGCCGGCACCGGCGGCGAGGGGCTGGCCCTGATCGCCAGTCAGTCGCTCGATGCGCTGATCC
TCGACGTCAACCTGCCGGACATGAGCGGGTTCGACATCGTGCGTAAACTGCGCGCCGACCCGGGCACCGCCCTGCTTCCG
GTGATCCACGTGTCCGCCGCGTCGATCCAGACCGGCGACATCATCACCGGCCTCGATGCCGGGGCCGATGCCTACCTGAT
TCATCCGGTCGATCCCGACGTGCTGCTGGCAACGTTGCGCACCCTGCTGCGGGTGCGTGACACGGAGAACGCGTTGCGCG
AAAGCGAGGCGCGTTTCCGCGAGATCTTCGTCAACGTCTCCGCACCCATCGCGGTGCTCGATGCCGATCTGAAAGTCCAT
GAGTGCAATCACGCCTTTTCCCAGCTGATCCAGGACAACCGCGACCCGCAGACCCTCAGCGAATGCTTTGCCGAGGATCA
GAGCGCGATCCTCGACGAACTGCGCCTGCGACTGGTGGACGGCGAGCGCTGGAAGGGCACGCTGAACATGCGCGTGCAGG
GTGAGGTTCGCGAGACCGAATGGCAGATTTCGCCCTACCGGACTCCGAAGCTGAGCCTGGTGTTCGTCGAAGACGTCACC
GAACACCGTCATCGCGAGCGCTCGCACCTGGCGCAGCTGGACGACACCACCACGCAACTGGCCAAGGAAGTCGCCGACCG
GGTACGCGCCGAATCGCAACTGCTGCAAGTACAGAAAATGGATGCGCTGGGCAAGCTCACCGGCGGCATCGCCCATGACT
TCAACAACCTGCTGACCGGGATCATCACCAGCCTCGAACTGATCCAGAAACGTGTTGCCGATGGCCGAACGGACAAGGTC
CAGTTCTACGCCGAAGCGGCTCTGAACTCGGCGAGGAGCGCGGCCTCGCTCACCCATCGCCTGTTGGCGTTTGCCCGTCA
GCAACCACTCGACACCCGTCCGGTCGACATCAACAGACACGTCCGCTCGCTCGAAGAATTGCTGGTGCGCACCATCGGCG
AACGCATCGCCCTCAAGCTCGAATTGACCACCAAACCTGCCATCGCGCTGGTCGATCCGATTCAGCTCGAAAGTGCGGTG
CTCAATCTGGTGATCAATGCCCGGGACGCATTGCCACGGGGCGGCAATATCTGGGTCAGCACTTACGCGGCGTACTCCCA
CGGCGACCCGAACCTCGCCGATGGATCCTACGTGGCGCTATCGGTGCGCGATGACGGTACCGGCATCGAGCACAACGTGA
TCGACAAGGTGTTCGAGCCGTTCTTCACCACCAAGCCGCTGGGCCAGGGCACCGGGCTGGGGCTGTCGACGATCTACGGT
TTTGCCCGTCAGTCCGGTGGCGATGCGCACATCCGCAGCGTCGCGCGACGCGGCACCGAAGTGACGATCATGCTGCCGGC
CACCAGCGATCCGACCGCTGTCGATGTGGCCCCGGTGACGATTGATCCGCAAGGCTCGGGCGAACATGTGTTGATCGTCG
AAGACATGCCGGCGGTACGCCTGTTCGTCACCGAAGTGCTGGAAGACGCCGGTTACCGCTGCACCCAGGCCGGCGATATC
GAAACGGCGCTGGAACGCTTGCAGAACGACGCGTCGATCGACCTGCTGCTGACTGACGTTGGTCTGCCACGCATGACCGG
CCGTGAACTGGCCGACGTTGCCCGGGGCTGGCGTGAGGGGTTGCCGATCCTGTTCATGACCGGTTATGCGGAAACCGCGA
TCAACCGCCAGGTGTTCCTCGGGGCGGGTATGGACATGCTGGTCAAACCGTTTCAGATCAGCGCATTGCTGGACAAGGTG
CGTCGCACGCTCGACGGTGCCTGA

Upstream 100 bases:

>100_bases
GCTGAATTGCTCGGTGGTGAGGTTGGTGTCGAAAGTACGCCGGGCGTGGGCTCAAGCTTTTTCGTGATCATTCCGCTGGC
ACTTGCCCAGGAGAACGTCG

Downstream 100 bases:

>100_bases
TGCACCTAGCGGCTGAGGGCGCGGGCGAGAAACGGCGCAGTCCGGCTCTTCTTGCTCGCCGCCACTTTCTGCGGCGTCCC
GGCCACGACGATCCGGCCGC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MKHDIRLLIVDDNVATRYALRRRLERHGYEVLEAGTGGEGLALIASQSLDALILDVNLPDMSGFDIVRKLRADPGTALLP
VIHVSAASIQTGDIITGLDAGADAYLIHPVDPDVLLATLRTLLRVRDTENALRESEARFREIFVNVSAPIAVLDADLKVH
ECNHAFSQLIQDNRDPQTLSECFAEDQSAILDELRLRLVDGERWKGTLNMRVQGEVRETEWQISPYRTPKLSLVFVEDVT
EHRHRERSHLAQLDDTTTQLAKEVADRVRAESQLLQVQKMDALGKLTGGIAHDFNNLLTGIITSLELIQKRVADGRTDKV
QFYAEAALNSARSAASLTHRLLAFARQQPLDTRPVDINRHVRSLEELLVRTIGERIALKLELTTKPAIALVDPIQLESAV
LNLVINARDALPRGGNIWVSTYAAYSHGDPNLADGSYVALSVRDDGTGIEHNVIDKVFEPFFTTKPLGQGTGLGLSTIYG
FARQSGGDAHIRSVARRGTEVTIMLPATSDPTAVDVAPVTIDPQGSGEHVLIVEDMPAVRLFVTEVLEDAGYRCTQAGDI
ETALERLQNDASIDLLLTDVGLPRMTGRELADVARGWREGLPILFMTGYAETAINRQVFLGAGMDMLVKPFQISALLDKV
RRTLDGA

Sequences:

>Translated_647_residues
MKHDIRLLIVDDNVATRYALRRRLERHGYEVLEAGTGGEGLALIASQSLDALILDVNLPDMSGFDIVRKLRADPGTALLP
VIHVSAASIQTGDIITGLDAGADAYLIHPVDPDVLLATLRTLLRVRDTENALRESEARFREIFVNVSAPIAVLDADLKVH
ECNHAFSQLIQDNRDPQTLSECFAEDQSAILDELRLRLVDGERWKGTLNMRVQGEVRETEWQISPYRTPKLSLVFVEDVT
EHRHRERSHLAQLDDTTTQLAKEVADRVRAESQLLQVQKMDALGKLTGGIAHDFNNLLTGIITSLELIQKRVADGRTDKV
QFYAEAALNSARSAASLTHRLLAFARQQPLDTRPVDINRHVRSLEELLVRTIGERIALKLELTTKPAIALVDPIQLESAV
LNLVINARDALPRGGNIWVSTYAAYSHGDPNLADGSYVALSVRDDGTGIEHNVIDKVFEPFFTTKPLGQGTGLGLSTIYG
FARQSGGDAHIRSVARRGTEVTIMLPATSDPTAVDVAPVTIDPQGSGEHVLIVEDMPAVRLFVTEVLEDAGYRCTQAGDI
ETALERLQNDASIDLLLTDVGLPRMTGRELADVARGWREGLPILFMTGYAETAINRQVFLGAGMDMLVKPFQISALLDKV
RRTLDGA
>Mature_647_residues
MKHDIRLLIVDDNVATRYALRRRLERHGYEVLEAGTGGEGLALIASQSLDALILDVNLPDMSGFDIVRKLRADPGTALLP
VIHVSAASIQTGDIITGLDAGADAYLIHPVDPDVLLATLRTLLRVRDTENALRESEARFREIFVNVSAPIAVLDADLKVH
ECNHAFSQLIQDNRDPQTLSECFAEDQSAILDELRLRLVDGERWKGTLNMRVQGEVRETEWQISPYRTPKLSLVFVEDVT
EHRHRERSHLAQLDDTTTQLAKEVADRVRAESQLLQVQKMDALGKLTGGIAHDFNNLLTGIITSLELIQKRVADGRTDKV
QFYAEAALNSARSAASLTHRLLAFARQQPLDTRPVDINRHVRSLEELLVRTIGERIALKLELTTKPAIALVDPIQLESAV
LNLVINARDALPRGGNIWVSTYAAYSHGDPNLADGSYVALSVRDDGTGIEHNVIDKVFEPFFTTKPLGQGTGLGLSTIYG
FARQSGGDAHIRSVARRGTEVTIMLPATSDPTAVDVAPVTIDPQGSGEHVLIVEDMPAVRLFVTEVLEDAGYRCTQAGDI
ETALERLQNDASIDLLLTDVGLPRMTGRELADVARGWREGLPILFMTGYAETAINRQVFLGAGMDMLVKPFQISALLDKV
RRTLDGA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=312, Percent_Identity=30.4487179487179, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=31.0606060606061, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=29.8850574712644, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=393, Percent_Identity=25.4452926208651, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=29.1338582677165, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788521, Length=168, Percent_Identity=35.1190476190476, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789809, Length=129, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786911, Length=144, Percent_Identity=38.8888888888889, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=34.1880341880342, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=124, Percent_Identity=40.3225806451613, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=130, Percent_Identity=33.0769230769231, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71123; Mature: 71123

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHDIRLLIVDDNVATRYALRRRLERHGYEVLEAGTGGEGLALIASQSLDALILDVNLPD
CCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCEEEEEECCCC
MSGFDIVRKLRADPGTALLPVIHVSAASIQTGDIITGLDAGADAYLIHPVDPDVLLATLR
CCCHHHHHHHHCCCCCEEEHEEEEECCCEECCCEEECCCCCCCEEEEECCCHHHHHHHHH
TLLRVRDTENALRESEARFREIFVNVSAPIAVLDADLKVHECNHAFSQLIQDNRDPQTLS
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCEEEHHHHHHHHHHHCCCCHHHHH
ECFAEDQSAILDELRLRLVDGERWKGTLNMRVQGEVRETEWQISPYRTPKLSLVFVEDVT
HHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEECCEEEECCCCCCCEEEEEEHHHH
EHRHRERSHLAQLDDTTTQLAKEVADRVRAESQLLQVQKMDALGKLTGGIAHDFNNLLTG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITSLELIQKRVADGRTDKVQFYAEAALNSARSAASLTHRLLAFARQQPLDTRPVDINRH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VRSLEELLVRTIGERIALKLELTTKPAIALVDPIQLESAVLNLVINARDALPRGGNIWVS
HHHHHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TYAAYSHGDPNLADGSYVALSVRDDGTGIEHNVIDKVFEPFFTTKPLGQGTGLGLSTIYG
EEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FARQSGGDAHIRSVARRGTEVTIMLPATSDPTAVDVAPVTIDPQGSGEHVLIVEDMPAVR
HHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHH
LFVTEVLEDAGYRCTQAGDIETALERLQNDASIDLLLTDVGLPRMTGRELADVARGWREG
HHHHHHHHHCCCEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
LPILFMTGYAETAINRQVFLGAGMDMLVKPFQISALLDKVRRTLDGA
CCEEEEECCHHHHCCCEEEEECCHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHDIRLLIVDDNVATRYALRRRLERHGYEVLEAGTGGEGLALIASQSLDALILDVNLPD
CCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCEEEEEECCCC
MSGFDIVRKLRADPGTALLPVIHVSAASIQTGDIITGLDAGADAYLIHPVDPDVLLATLR
CCCHHHHHHHHCCCCCEEEHEEEEECCCEECCCEEECCCCCCCEEEEECCCHHHHHHHHH
TLLRVRDTENALRESEARFREIFVNVSAPIAVLDADLKVHECNHAFSQLIQDNRDPQTLS
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCEEEHHHHHHHHHHHCCCCHHHHH
ECFAEDQSAILDELRLRLVDGERWKGTLNMRVQGEVRETEWQISPYRTPKLSLVFVEDVT
HHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEECCEEEECCCCCCCEEEEEEHHHH
EHRHRERSHLAQLDDTTTQLAKEVADRVRAESQLLQVQKMDALGKLTGGIAHDFNNLLTG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITSLELIQKRVADGRTDKVQFYAEAALNSARSAASLTHRLLAFARQQPLDTRPVDINRH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
VRSLEELLVRTIGERIALKLELTTKPAIALVDPIQLESAVLNLVINARDALPRGGNIWVS
HHHHHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TYAAYSHGDPNLADGSYVALSVRDDGTGIEHNVIDKVFEPFFTTKPLGQGTGLGLSTIYG
EEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FARQSGGDAHIRSVARRGTEVTIMLPATSDPTAVDVAPVTIDPQGSGEHVLIVEDMPAVR
HHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHH
LFVTEVLEDAGYRCTQAGDIETALERLQNDASIDLLLTDVGLPRMTGRELADVARGWREG
HHHHHHHHHCCCEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC
LPILFMTGYAETAINRQVFLGAGMDMLVKPFQISALLDKVRRTLDGA
CCEEEEECCHHHHCCCEEEEECCHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA