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The map label for this gene is metH [H]

Identifier: 77459329

GI number: 77459329

Start: 3560284

End: 3563994

Strand: Direct

Name: metH [H]

Synonym: Pfl01_3107

Alternate gene names: 77459329

Gene position: 3560284-3563994 (Clockwise)

Preceding gene: 77459325

Following gene: 77459331

Centisome position: 55.3

GC content: 62.41

Gene sequence:

>3711_bases
ATGTCCGATCGCAGCGTCCGCCTTCAAGCTCTCAAGCAAGCTCTCAAAGAGCGCATCCTGATTCTCGACGGCGGCATGGG
CACGATGATCCAGAGCTACAAGCTCGAAGAGCAGGATTATCGCGGCAAACGCTTCGCCGACTGGCCGAGCGACGTCAAGG
GCAACAACGACCTGTTGGTGCTGACCCGCCCGGACGTGATCGGCGGCATCGAGAAAGCCTATCTGGATGCCGGTGCCGAC
ATCCTCGAGACCAACACCTTCAACGCCACGCAGATTTCCATGGCCGACTACGGCATGGAAGAACTGGTCTACGAACTCAA
CGTAGAAGGCGCCCGTCTGGCACGCAAGGTCGCCGACGCGAAAACCCTCGAGACCCCCGACAAGCCGCGCTTCGTCGCCG
GCGTTCTCGGCCCGACCAGCCGCACCTGCTCGCTGTCGCCGGACGTCAACAACCCGGGCTATCGCAACGTCACCTTCGAT
GAGCTGGTCGAAAACTACACCGAGGCCACCAAAGGCCTGATCGAGGGCGGCGCGGATCTGATCCTGATCGAAACCATCTT
CGACACCCTCAACGCCAAAGCCGCGATCTTCGCCGTGCAAGGCGTGTTCGAAGAACTGGGCTTCGAATTGCCGATCATGA
TCTCCGGCACCATCACCGACGCCTCCGGCCGTACCCTGTCGGGCCAGACCACCGAAGCGTTCTGGAACTCCGTGGCTCAC
GCCAAACCGATTTCCGTCGGTCTTAACTGCGCCCTCGGCGCCCGCGAACTGCGTCCGTACCTGGAAGAGCTGTCGGACAA
GGCCAGCACCCACGTTTCGGCGCACCCGAACGCCGGCCTGCCGAACGAATTCGGCGAGTACGACGAGCTGCCGGTGGACA
CCGCCAAGGTCATCGAAGAGTTCGCCCAGAGCGGTTTCCTCAACATCGTCGGCGGTTGCTGCGGCACCACGCCGGGCCAT
ATCGAAGCCATCGCCAAAGCCGTTGCCGGTTACGCGCCACGGCAGATTCCGGACATTCCCAAGGCCTGCCGCCTGTCGGG
TCTGGAACCGTTCACCATTGATCGCAGCTCGCTGTTCGTCAACGTCGGCGAGCGGACCAACATCACCGGGTCCGCGAAAT
TTGCCCGGCTGATCCGTGAAGACAACTACACCGAAGCCCTGGAAGTCGCCCTGCAGCAGGTCGAGGCCGGCGCCCAGGTG
ATCGACATCAACATGGACGAAGGGATGCTCGATTCGAAGAAGGCCATGGTGACCTTCCTCAATCTGATTGCCGGCGAACC
GGACATCTCCCGCGTACCGATCATGATCGACTCCTCGAAATGGGACGTGATCGAAGCCGGCCTCAAGTGCATTCAGGGCA
AGGGCATCGTCAACTCGATCAGCATGAAAGAAGGCGTCGAGCAGTTCATCCACCACGCCAAACTGTGCAAGCGCTATGGC
GCCGCCGTGGTGGTGATGGCGTTCGACGAAGCCGGCCAGGCTGACACCGAAGCGCGCAAGAAAGAGATCTGCAAACGCTC
CTACGACATTCTGGTCAACGAAGTCGGCTTCCCGCCGGAAGACATCATTTTCGACCCGAACATCTTCGCCGTGGCCACCG
GCATCGAAGAACACAACAACTACGCTGTGGACTTCATCAACGCCTGTGCCTACATCCGCGACGAGCTGCCGTATGCCCTG
AGCTCCGGCGGCGTGTCCAACGTGTCGTTCTCGTTCCGCGGCAACAACCCGGTGCGCGAGGCGATCCACTCGGTGTTCCT
GCTGTACGCGATCCGCGCCGGCCTGACCATGGGTATCGTCAACGCCGGTCAGCTGGAGATCTACGACCAGATCCCGCAGG
AACTGCGCGACGCCGTTGAAGACGTGATCCTCAACCGCACGCCGGAAGGCACCGACGCCCTCCTCGCCATCGCCGACAAG
TACAAGGGCGACGGCAGCGTCAAGGAAGCCGAGACCGAAGAATGGCGCGGCTGGGACGTCAACAAACGTCTGGAACATGC
GCTGGTCAAGGGCATCACCACCCACATCGTCGAAGACACCGAAGAATCCCGTCAGTCCTTCGCCCGCCCGATCGAAGTGA
TCGAAGGCCCGCTGATGTCCGGCATGAACATCGTCGGCGACCTGTTCGGCGCCGGCAAAATGTTCCTGCCGCAAGTGGTG
AAATCCGCCCGCGTGATGAAGCAGGCCGTGGCGCACCTGATTCCGTTCATCGAACTGGAAAAAGGCGACAAGCCGGAAGC
CAAGGGCAAGATCCTGATGGCCACGGTCAAAGGCGACGTGCACGACATCGGCAAGAACATCGTCGGCGTGGTGCTGGGTT
GCAACGGCTACGACATCGTCGACCTCGGCGTGATGGTGCCGGCGGAGAAGATCCTGCAGGTGGCCAAGGAGCAGAAGTGC
GACATCATCGGCCTGTCCGGTCTGATCACCCCGTCGCTGGATGAGATGGTCCATGTGGCCCGCGAGATGCAGCGCCAGGA
CTTCCACCTGCCGCTGATGATCGGCGGCGCGACCACCTCCAAGGCGCACACGGCGGTGAAGATCGAGCCCAAGTACAGCA
ACGACGCAGTGGTCTACGTGACCGACGCCTCCCGCGCCGTGGGCGTGGCGACGCAGTTGCTGTCCAAGGAACTGAAAGCC
GGTTTCGTCCAGAAGACCCGCGAAGAGTACATCGACGTCCGCGAGCGCACCGCCAACCGCAGCGCCCGCACCGAACGCCT
GAGCTACGCCGCCGCGATCGCCAAGAAGCCGCAGTTCGACTGGGCCACTTACACCCCGGTCAAACCGACCTTCACCGGCA
CCCGCGTGCTGGACAACATCGACCTCAACGTTCTCGCCGAGTACATCGACTGGACGCCGTTCTTCATCTCCTGGGACCTG
GCCGGCAAGTTCCCGCGCATCCTCGAAGACGAAGTGGTCGGCGAAGCGGCGACCGCGCTGTACAAGGACGCTCGCGAGAT
GCTGACCAAGCTGATCGACGAGAAACTGATCAGCGCCCGTGCGGTGTTCGGCTTCTGGCCGGCCAATCAGGTGCACGACG
ACGATATCGAGCTGTACGGCGATGACGGCAAGCCAATGGCGCGCCTGCATCACCTGCGCCAGCAGATCATCAAGACCGAC
GGCAAACCGAACTTCTCCCTCGCCGACTTCGTCGCGCCGAAGGACAGCGAAGTGACCGACTACGTTGGTGGTTTCATCAC
CACCGCCGGGATCGGCGCCGAAGAAGTGGCCAAGGCCTATCAGGACGCCGGCGACGATTACAACTCGATCATGGTCAAGG
CCCTGGCCGACCGTCTGGCCGAGGCGTGCGCCGAGTGGCTGCACCAGCAGGTGCGCAAAGAGCACTGGGGTTACGCCAAG
GATGAAGCCCTCGATAACGAGGCGCTGATCAAAGAGCAGTATTCCGGCATCCGCCCTGCCCCCGGCTACCCGGCGTGCCC
GGATCACACCGAGAAGGCCACCCTGTTCGCCCTGCTCGACCCTGAAGCACAGGAAATGCGCGCCGGCCGCAGCGGTGTGT
TCCTCACCGAGCACTACGCGATGTTCCCGGCGGCAGCCGTCAGCGGCTGGTACTTCGCCCATCCGCAGGCGCAGTACTTC
GCCGTGGGCAAGGTCGACAAGGATCAGGTGCAGAGCTACACCTCGCGCAAAGGCCAGGAACTGAGCCTGACCGAGCGCTG
GCTGGCACCCAATCTGGGCTACGACAACTGA

Upstream 100 bases:

>100_bases
CCAACATGAGCGATATTCATGCAAAAGCGCCACATGCTCTAAATCCGCACAGGTTTGTTATGATCCCGCTCCTTCGTCAT
GGTCTTTTCGAGTAGTCCCA

Downstream 100 bases:

>100_bases
GCCATCAGATTCGGTCCGAGTCGTCGGAAGAGGAGGAACCCTCCGGTTCCTCCCACTCGCGATCAGCCAGCCATTGTTCA
AGTGTCTCCCGGGATATTCC

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1236; Mature: 1235

Protein sequence:

>1236_residues
MSDRSVRLQALKQALKERILILDGGMGTMIQSYKLEEQDYRGKRFADWPSDVKGNNDLLVLTRPDVIGGIEKAYLDAGAD
ILETNTFNATQISMADYGMEELVYELNVEGARLARKVADAKTLETPDKPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFD
ELVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEELGFELPIMISGTITDASGRTLSGQTTEAFWNSVAH
AKPISVGLNCALGARELRPYLEELSDKASTHVSAHPNAGLPNEFGEYDELPVDTAKVIEEFAQSGFLNIVGGCCGTTPGH
IEAIAKAVAGYAPRQIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREDNYTEALEVALQQVEAGAQV
IDINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISMKEGVEQFIHHAKLCKRYG
AAVVVMAFDEAGQADTEARKKEICKRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFINACAYIRDELPYAL
SSGGVSNVSFSFRGNNPVREAIHSVFLLYAIRAGLTMGIVNAGQLEIYDQIPQELRDAVEDVILNRTPEGTDALLAIADK
YKGDGSVKEAETEEWRGWDVNKRLEHALVKGITTHIVEDTEESRQSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVAKEQKC
DIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVVYVTDASRAVGVATQLLSKELKA
GFVQKTREEYIDVRERTANRSARTERLSYAAAIAKKPQFDWATYTPVKPTFTGTRVLDNIDLNVLAEYIDWTPFFISWDL
AGKFPRILEDEVVGEAATALYKDAREMLTKLIDEKLISARAVFGFWPANQVHDDDIELYGDDGKPMARLHHLRQQIIKTD
GKPNFSLADFVAPKDSEVTDYVGGFITTAGIGAEEVAKAYQDAGDDYNSIMVKALADRLAEACAEWLHQQVRKEHWGYAK
DEALDNEALIKEQYSGIRPAPGYPACPDHTEKATLFALLDPEAQEMRAGRSGVFLTEHYAMFPAAAVSGWYFAHPQAQYF
AVGKVDKDQVQSYTSRKGQELSLTERWLAPNLGYDN

Sequences:

>Translated_1236_residues
MSDRSVRLQALKQALKERILILDGGMGTMIQSYKLEEQDYRGKRFADWPSDVKGNNDLLVLTRPDVIGGIEKAYLDAGAD
ILETNTFNATQISMADYGMEELVYELNVEGARLARKVADAKTLETPDKPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFD
ELVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEELGFELPIMISGTITDASGRTLSGQTTEAFWNSVAH
AKPISVGLNCALGARELRPYLEELSDKASTHVSAHPNAGLPNEFGEYDELPVDTAKVIEEFAQSGFLNIVGGCCGTTPGH
IEAIAKAVAGYAPRQIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREDNYTEALEVALQQVEAGAQV
IDINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISMKEGVEQFIHHAKLCKRYG
AAVVVMAFDEAGQADTEARKKEICKRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFINACAYIRDELPYAL
SSGGVSNVSFSFRGNNPVREAIHSVFLLYAIRAGLTMGIVNAGQLEIYDQIPQELRDAVEDVILNRTPEGTDALLAIADK
YKGDGSVKEAETEEWRGWDVNKRLEHALVKGITTHIVEDTEESRQSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVAKEQKC
DIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVVYVTDASRAVGVATQLLSKELKA
GFVQKTREEYIDVRERTANRSARTERLSYAAAIAKKPQFDWATYTPVKPTFTGTRVLDNIDLNVLAEYIDWTPFFISWDL
AGKFPRILEDEVVGEAATALYKDAREMLTKLIDEKLISARAVFGFWPANQVHDDDIELYGDDGKPMARLHHLRQQIIKTD
GKPNFSLADFVAPKDSEVTDYVGGFITTAGIGAEEVAKAYQDAGDDYNSIMVKALADRLAEACAEWLHQQVRKEHWGYAK
DEALDNEALIKEQYSGIRPAPGYPACPDHTEKATLFALLDPEAQEMRAGRSGVFLTEHYAMFPAAAVSGWYFAHPQAQYF
AVGKVDKDQVQSYTSRKGQELSLTERWLAPNLGYDN
>Mature_1235_residues
SDRSVRLQALKQALKERILILDGGMGTMIQSYKLEEQDYRGKRFADWPSDVKGNNDLLVLTRPDVIGGIEKAYLDAGADI
LETNTFNATQISMADYGMEELVYELNVEGARLARKVADAKTLETPDKPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDE
LVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEELGFELPIMISGTITDASGRTLSGQTTEAFWNSVAHA
KPISVGLNCALGARELRPYLEELSDKASTHVSAHPNAGLPNEFGEYDELPVDTAKVIEEFAQSGFLNIVGGCCGTTPGHI
EAIAKAVAGYAPRQIPDIPKACRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREDNYTEALEVALQQVEAGAQVI
DINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISMKEGVEQFIHHAKLCKRYGA
AVVVMAFDEAGQADTEARKKEICKRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFINACAYIRDELPYALS
SGGVSNVSFSFRGNNPVREAIHSVFLLYAIRAGLTMGIVNAGQLEIYDQIPQELRDAVEDVILNRTPEGTDALLAIADKY
KGDGSVKEAETEEWRGWDVNKRLEHALVKGITTHIVEDTEESRQSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVVK
SARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVAKEQKCD
IIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVVYVTDASRAVGVATQLLSKELKAG
FVQKTREEYIDVRERTANRSARTERLSYAAAIAKKPQFDWATYTPVKPTFTGTRVLDNIDLNVLAEYIDWTPFFISWDLA
GKFPRILEDEVVGEAATALYKDAREMLTKLIDEKLISARAVFGFWPANQVHDDDIELYGDDGKPMARLHHLRQQIIKTDG
KPNFSLADFVAPKDSEVTDYVGGFITTAGIGAEEVAKAYQDAGDDYNSIMVKALADRLAEACAEWLHQQVRKEHWGYAKD
EALDNEALIKEQYSGIRPAPGYPACPDHTEKATLFALLDPEAQEMRAGRSGVFLTEHYAMFPAAAVSGWYFAHPQAQYFA
VGKVDKDQVQSYTSRKGQELSLTERWLAPNLGYDN

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1250, Percent_Identity=55.12, Blast_Score=1338, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1236, Percent_Identity=66.9093851132686, Blast_Score=1656, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1255, Percent_Identity=52.6693227091633, Blast_Score=1290, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 135777; Mature: 135645

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRSVRLQALKQALKERILILDGGMGTMIQSYKLEEQDYRGKRFADWPSDVKGNNDLLV
CCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEE
LTRPDVIGGIEKAYLDAGADILETNTFNATQISMADYGMEELVYELNVEGARLARKVADA
EECCHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHH
KTLETPDKPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDELVENYTEATKGLIEGGADL
HCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQGVFEELGFELPIMISGTITDASGRTLSGQTTEAFWNSVAH
EEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHHC
AKPISVGLNCALGARELRPYLEELSDKASTHVSAHPNAGLPNEFGEYDELPVDTAKVIEE
CCCCEECCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
FAQSGFLNIVGGCCGTTPGHIEAIAKAVAGYAPRQIPDIPKACRLSGLEPFTIDRSSLFV
HHHCCCCEEHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEECCCEEEE
NVGERTNITGSAKFARLIREDNYTEALEVALQQVEAGAQVIDINMDEGMLDSKKAMVTFL
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISMKEGVEQFIHHAKLCKRYG
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEAGQADTEARKKEICKRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEECHHHCCC
YAVDFINACAYIRDELPYALSSGGVSNVSFSFRGNNPVREAIHSVFLLYAIRAGLTMGIV
CHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEC
NAGQLEIYDQIPQELRDAVEDVILNRTPEGTDALLAIADKYKGDGSVKEAETEEWRGWDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCCCCCCCCHHCCCCCH
NKRLEHALVKGITTHIVEDTEESRQSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCCEE
DLGVMVPAEKILQVAKEQKCDIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTS
EECHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIEPKYSNDAVVYVTDASRAVGVATQLLSKELKAGFVQKTREEYIDVRERTANR
CCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SARTERLSYAAAIAKKPQFDWATYTPVKPTFTGTRVLDNIDLNVLAEYIDWTPFFISWDL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCEEEEEEC
AGKFPRILEDEVVGEAATALYKDAREMLTKLIDEKLISARAVFGFWPANQVHDDDIELYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEC
DDGKPMARLHHLRQQIIKTDGKPNFSLADFVAPKDSEVTDYVGGFITTAGIGAEEVAKAY
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
QDAGDDYNSIMVKALADRLAEACAEWLHQQVRKEHWGYAKDEALDNEALIKEQYSGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKATLFALLDPEAQEMRAGRSGVFLTEHYAMFPAAAVSGWYFAHPQAQYF
CCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCEEEEHHHHHHHHHHHCCEEEECCCCCEE
AVGKVDKDQVQSYTSRKGQELSLTERWLAPNLGYDN
EECCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDRSVRLQALKQALKERILILDGGMGTMIQSYKLEEQDYRGKRFADWPSDVKGNNDLLV
CCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCEEE
LTRPDVIGGIEKAYLDAGADILETNTFNATQISMADYGMEELVYELNVEGARLARKVADA
EECCHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHH
KTLETPDKPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDELVENYTEATKGLIEGGADL
HCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQGVFEELGFELPIMISGTITDASGRTLSGQTTEAFWNSVAH
EEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHHC
AKPISVGLNCALGARELRPYLEELSDKASTHVSAHPNAGLPNEFGEYDELPVDTAKVIEE
CCCCEECCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
FAQSGFLNIVGGCCGTTPGHIEAIAKAVAGYAPRQIPDIPKACRLSGLEPFTIDRSSLFV
HHHCCCCEEHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEECCCEEEE
NVGERTNITGSAKFARLIREDNYTEALEVALQQVEAGAQVIDINMDEGMLDSKKAMVTFL
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWDVIEAGLKCIQGKGIVNSISMKEGVEQFIHHAKLCKRYG
HHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEAGQADTEARKKEICKRSYDILVNEVGFPPEDIIFDPNIFAVATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEECHHHCCC
YAVDFINACAYIRDELPYALSSGGVSNVSFSFRGNNPVREAIHSVFLLYAIRAGLTMGIV
CHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEC
NAGQLEIYDQIPQELRDAVEDVILNRTPEGTDALLAIADKYKGDGSVKEAETEEWRGWDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCCCCCCCCHHCCCCCH
NKRLEHALVKGITTHIVEDTEESRQSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCCEE
DLGVMVPAEKILQVAKEQKCDIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTS
EECHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIEPKYSNDAVVYVTDASRAVGVATQLLSKELKAGFVQKTREEYIDVRERTANR
CCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SARTERLSYAAAIAKKPQFDWATYTPVKPTFTGTRVLDNIDLNVLAEYIDWTPFFISWDL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCEEEEEEC
AGKFPRILEDEVVGEAATALYKDAREMLTKLIDEKLISARAVFGFWPANQVHDDDIELYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEC
DDGKPMARLHHLRQQIIKTDGKPNFSLADFVAPKDSEVTDYVGGFITTAGIGAEEVAKAY
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
QDAGDDYNSIMVKALADRLAEACAEWLHQQVRKEHWGYAKDEALDNEALIKEQYSGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKATLFALLDPEAQEMRAGRSGVFLTEHYAMFPAAAVSGWYFAHPQAQYF
CCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCEEEEHHHHHHHHHHHCCEEEECCCCCEE
AVGKVDKDQVQSYTSRKGQELSLTERWLAPNLGYDN
EECCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]