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The map label for this gene is yfhM [H]

Identifier: 77459277

GI number: 77459277

Start: 3496934

End: 3497779

Strand: Reverse

Name: yfhM [H]

Synonym: Pfl01_3055

Alternate gene names: 77459277

Gene position: 3497779-3496934 (Counterclockwise)

Preceding gene: 77459278

Following gene: 77459276

Centisome position: 54.33

GC content: 64.66

Gene sequence:

>846_bases
ATGGAGTTCGAACACGTCACTTTCGACCTGCCACACGGAACCTTTCATGCGCTGAAGGGCGGCGATCCCGATGGTCAACC
GACGATCGTCTTGCACGGTTTCCCAGATCATCCGCCGACCGCGAAGATCTTCCTTGCCGAGCTCGGCCGCCGCGGCCGTC
ACGTCGTCGCACCCTGGCTACGCGGTTACGCGCCTTCCCCGACTGCGGGGCCGTTCAACTTCGCGGCTCTCACCAGCGAC
GTGCTCGCGCTGATCGACCGTTGGTCTCCGGAGCGCCCCGTGGAGTTGATTGGTCACGATTGGGGCGCCCTGATCACCTA
TGATGCCTGCGTCACCGCACCGGAGCGGATCGAACGCGCAGTCGCGCTCGCAATCCCTCACCCACTCACGTTCATGAGCC
GGCTGACGCACCTCCCTCAGCTACGCCGGAGCTGGTACATGGGGCTCTTTCAACTGCCTGGAAGCGGCTGGATCGCCACC
GCCCGCGATCTTGCCTTCATCGACAGCCTCTGGCGTCGATGGTCGCCCGGTTTCTCGCTCGATCCCGCTCTCAAGGCAGA
GCTACATGAGCATCTGCGCCAGAGCATGCCTGCGCCCCTAAAGTATTACCGGGCGATGCTGCGCCCCGGCATGATTGGTG
CGACGCGCCGTATGTCTCAGCCGATCACGGTGCCCCTGTTGCAGCTTCACGGCGCCAACGACGACTGCATCCTCCCCGCG
CATGTCGAAGACAGGCATCGGTTCGCCGCCCCGCACGCGATGGAAGTCGTCCCCGGCGTCGGTCACTTCCTGCACGTCGA
GGCCCCTGAAGCGATCGCGGAACGGATCGCGGCATGGGCCAAGTAG

Upstream 100 bases:

>100_bases
GCTTGGAGATGAGCATGGAGGCGCACATGTCCAAGACCAGAAACACCGAAGCCAGCATCAGCATTTCTCGACTGACCATT
TTTCAAAAAGGCAGAAACAC

Downstream 100 bases:

>100_bases
CGTCCTATCCTCCTTGCCCCGATCAAAGGCTAGCTGTTTAAAACGAAACAAAACGAGGAGATGTCATGACAGAGCAAAAA
GCCTATCAGGTCGCCGATTG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MEFEHVTFDLPHGTFHALKGGDPDGQPTIVLHGFPDHPPTAKIFLAELGRRGRHVVAPWLRGYAPSPTAGPFNFAALTSD
VLALIDRWSPERPVELIGHDWGALITYDACVTAPERIERAVALAIPHPLTFMSRLTHLPQLRRSWYMGLFQLPGSGWIAT
ARDLAFIDSLWRRWSPGFSLDPALKAELHEHLRQSMPAPLKYYRAMLRPGMIGATRRMSQPITVPLLQLHGANDDCILPA
HVEDRHRFAAPHAMEVVPGVGHFLHVEAPEAIAERIAAWAK

Sequences:

>Translated_281_residues
MEFEHVTFDLPHGTFHALKGGDPDGQPTIVLHGFPDHPPTAKIFLAELGRRGRHVVAPWLRGYAPSPTAGPFNFAALTSD
VLALIDRWSPERPVELIGHDWGALITYDACVTAPERIERAVALAIPHPLTFMSRLTHLPQLRRSWYMGLFQLPGSGWIAT
ARDLAFIDSLWRRWSPGFSLDPALKAELHEHLRQSMPAPLKYYRAMLRPGMIGATRRMSQPITVPLLQLHGANDDCILPA
HVEDRHRFAAPHAMEVVPGVGHFLHVEAPEAIAERIAAWAK
>Mature_281_residues
MEFEHVTFDLPHGTFHALKGGDPDGQPTIVLHGFPDHPPTAKIFLAELGRRGRHVVAPWLRGYAPSPTAGPFNFAALTSD
VLALIDRWSPERPVELIGHDWGALITYDACVTAPERIERAVALAIPHPLTFMSRLTHLPQLRRSWYMGLFQLPGSGWIAT
ARDLAFIDSLWRRWSPGFSLDPALKAELHEHLRQSMPAPLKYYRAMLRPGMIGATRRMSQPITVPLLQLHGANDDCILPA
HVEDRHRFAAPHAMEVVPGVGHFLHVEAPEAIAERIAAWAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=280, Percent_Identity=28.2142857142857, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13376164, Length=280, Percent_Identity=28.2142857142857, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI218777837, Length=280, Percent_Identity=23.9285714285714, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=278, Percent_Identity=22.6618705035971, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562298, Length=282, Percent_Identity=23.4042553191489, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 31347; Mature: 31347

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEHVTFDLPHGTFHALKGGDPDGQPTIVLHGFPDHPPTAKIFLAELGRRGRHVVAPWL
CCCCEEEEECCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECHHH
RGYAPSPTAGPFNFAALTSDVLALIDRWSPERPVELIGHDWGALITYDACVTAPERIERA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEHHHHCCHHHHHHH
VALAIPHPLTFMSRLTHLPQLRRSWYMGLFQLPGSGWIATARDLAFIDSLWRRWSPGFSL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DPALKAELHEHLRQSMPAPLKYYRAMLRPGMIGATRRMSQPITVPLLQLHGANDDCILPA
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEECCCCCCEEEC
HVEDRHRFAAPHAMEVVPGVGHFLHVEAPEAIAERIAAWAK
CCCCHHHHCCCCHHHHCCCCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MEFEHVTFDLPHGTFHALKGGDPDGQPTIVLHGFPDHPPTAKIFLAELGRRGRHVVAPWL
CCCCEEEEECCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEECHHH
RGYAPSPTAGPFNFAALTSDVLALIDRWSPERPVELIGHDWGALITYDACVTAPERIERA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEHHHHCCHHHHHHH
VALAIPHPLTFMSRLTHLPQLRRSWYMGLFQLPGSGWIATARDLAFIDSLWRRWSPGFSL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DPALKAELHEHLRQSMPAPLKYYRAMLRPGMIGATRRMSQPITVPLLQLHGANDDCILPA
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEECCCCCCEEEC
HVEDRHRFAAPHAMEVVPGVGHFLHVEAPEAIAERIAAWAK
CCCCHHHHCCCCHHHHCCCCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]