Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 77459276

GI number: 77459276

Start: 3495996

End: 3496868

Strand: Reverse

Name: ubiE [C]

Synonym: Pfl01_3054

Alternate gene names: 77459276

Gene position: 3496868-3495996 (Counterclockwise)

Preceding gene: 77459277

Following gene: 77459275

Centisome position: 54.31

GC content: 65.29

Gene sequence:

>873_bases
ATGACAGAGCAAAAAGCCTATCAGGTCGCCGATTGGAATGGCGAAAGTGGAGAGTACTGGGCCGCCAACCAGGCCCGGCT
CGACGCCATGTTTGCGGTATTTGGCCAGGCCGCGATAGAAGCCGCGGCGCCCGCCACCGGCGAACGCGTGCTTGACGTCG
GTTGCGGCGCGGGCGCGTCGAGTCTGGCTCTGGCCGCACGCGTCGGTGCGGGCGGACATGTGCTGGGCGTAGACATATCC
GAACCGCTAATTGGACGAGCCCGCGAGCTTGCGCCGCAGGATACGCCGGTCCTGTTCCAGGTGGCCGACGCCAGTAACGC
CGAGCTGCCCGAGGGCGCGTTTGACATCCTTTTCTCGCGTTTCGGGGTGATGTTCTTCGACGATCCGACAGGGGCATTCG
CCCATATGCGACGCGCGCTCCGACCGGGCGGGCGGGTCGCTTTCATCTGCTGGCGCGGCGTGGCCGAGAACGATTGGGTA
CGCCTGCCGATGGGCGCGATCAGGGGCGTCGTCCCGCCGATCGCAACGCTTGATCCCGAAGCACCCGGACCATTCTCGTT
CGGTGACCGGGGGCGCGTGACACGTATCCTGACGGATGCAGGCTTTACCGATATCACTTTTGCGCCGTTCGATGTGTCCA
TCCCGTTCGGCGAAGGCGAGACTCGGGATGCTGCGATCGACGACGCGGTAAGGATGGCGTTCGAGGGCGGCCCGCTGTCG
CTTGTGCTCGCACATCAAAGCGATGACATCCGCGCCCAAGCTTCAGCGGCGATTCGCGCCGCTTTCGCCAGCCTCCCCGG
CGAACGGTCGGTGATGATCGGCGGCGCGGCGTGGATCGTCATGGCAGGTAATCCGGCAACCAGCGCCTGTTAG

Upstream 100 bases:

>100_bases
CGATCGCGGAACGGATCGCGGCATGGGCCAAGTAGCGTCCTATCCTCCTTGCCCCGATCAAAGGCTAGCTGTTTAAAACG
AAACAAAACGAGGAGATGTC

Downstream 100 bases:

>100_bases
CAGGGATGTGCCCCTCACGCTCAGTACAGCAGTGCGACTTAGGTAAGTTAGATTAATGTCCCTTTTGGCTTGGTGATCCG
TCCTTGGCAAAAGCGATACC

Product: UbiE/COQ5 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; S-Adenosyl-L-Methionine-Dependent Methyltransferase; Methyltransferase Protein; Methyltransferase UbiE/COQ5 Family; SAM-Dependent Methyltransferase; Methlytransferase UbiE/COQ5 Family Protein; UbiE/COQ5 Family Methlytransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; UbiE/COQ5 Methyltransferase; UbiE/COQ5 Family Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; Aklanonic Acid Methyl Transferase; Demethylmenaquinone Methyltransferase; Methyltransferase Domain Family

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTEQKAYQVADWNGESGEYWAANQARLDAMFAVFGQAAIEAAAPATGERVLDVGCGAGASSLALAARVGAGGHVLGVDIS
EPLIGRARELAPQDTPVLFQVADASNAELPEGAFDILFSRFGVMFFDDPTGAFAHMRRALRPGGRVAFICWRGVAENDWV
RLPMGAIRGVVPPIATLDPEAPGPFSFGDRGRVTRILTDAGFTDITFAPFDVSIPFGEGETRDAAIDDAVRMAFEGGPLS
LVLAHQSDDIRAQASAAIRAAFASLPGERSVMIGGAAWIVMAGNPATSAC

Sequences:

>Translated_290_residues
MTEQKAYQVADWNGESGEYWAANQARLDAMFAVFGQAAIEAAAPATGERVLDVGCGAGASSLALAARVGAGGHVLGVDIS
EPLIGRARELAPQDTPVLFQVADASNAELPEGAFDILFSRFGVMFFDDPTGAFAHMRRALRPGGRVAFICWRGVAENDWV
RLPMGAIRGVVPPIATLDPEAPGPFSFGDRGRVTRILTDAGFTDITFAPFDVSIPFGEGETRDAAIDDAVRMAFEGGPLS
LVLAHQSDDIRAQASAAIRAAFASLPGERSVMIGGAAWIVMAGNPATSAC
>Mature_289_residues
TEQKAYQVADWNGESGEYWAANQARLDAMFAVFGQAAIEAAAPATGERVLDVGCGAGASSLALAARVGAGGHVLGVDISE
PLIGRARELAPQDTPVLFQVADASNAELPEGAFDILFSRFGVMFFDDPTGAFAHMRRALRPGGRVAFICWRGVAENDWVR
LPMGAIRGVVPPIATLDPEAPGPFSFGDRGRVTRILTDAGFTDITFAPFDVSIPFGEGETRDAAIDDAVRMAFEGGPLSL
VLAHQSDDIRAQASAAIRAAFASLPGERSVMIGGAAWIVMAGNPATSAC

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30355; Mature: 30223

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQKAYQVADWNGESGEYWAANQARLDAMFAVFGQAAIEAAAPATGERVLDVGCGAGAS
CCCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
SLALAARVGAGGHVLGVDISEPLIGRARELAPQDTPVLFQVADASNAELPEGAFDILFSR
HHHEEEEECCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
FGVMFFDDPTGAFAHMRRALRPGGRVAFICWRGVAENDWVRLPMGAIRGVVPPIATLDPE
CCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHHHCCCCCCCCCCC
APGPFSFGDRGRVTRILTDAGFTDITFAPFDVSIPFGEGETRDAAIDDAVRMAFEGGPLS
CCCCCCCCCCCCEEEEEECCCCCCEEECCEEEEEECCCCCCCCHHHHHHHHHEECCCCEE
LVLAHQSDDIRAQASAAIRAAFASLPGERSVMIGGAAWIVMAGNPATSAC
EEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEECCCCCCCC
>Mature Secondary Structure 
TEQKAYQVADWNGESGEYWAANQARLDAMFAVFGQAAIEAAAPATGERVLDVGCGAGAS
CCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
SLALAARVGAGGHVLGVDISEPLIGRARELAPQDTPVLFQVADASNAELPEGAFDILFSR
HHHEEEEECCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
FGVMFFDDPTGAFAHMRRALRPGGRVAFICWRGVAENDWVRLPMGAIRGVVPPIATLDPE
CCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHHHCCCCCCCCCCC
APGPFSFGDRGRVTRILTDAGFTDITFAPFDVSIPFGEGETRDAAIDDAVRMAFEGGPLS
CCCCCCCCCCCCEEEEEECCCCCCEEECCEEEEEECCCCCCCCHHHHHHHHHEECCCCEE
LVLAHQSDDIRAQASAAIRAAFASLPGERSVMIGGAAWIVMAGNPATSAC
EEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA