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The map label for this gene is hlyB [H]

Identifier: 77459195

GI number: 77459195

Start: 3407543

End: 3409681

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_2970

Alternate gene names: 77459195

Gene position: 3409681-3407543 (Counterclockwise)

Preceding gene: 77459196

Following gene: 77459194

Centisome position: 52.96

GC content: 55.91

Gene sequence:

>2139_bases
ATGCGTTTTGCGCGTGTATCCATCAAGTGGAAAATCACACTGTTGGCAGGATTTTGCCTGCTGTGTACCGTCGTACTGTT
GGTGGGTACGTCCCTGTATCGCATGGACACCAGTCTGGCATTGGTCAAATCAGCCAACTCACAGATGCTTGAGGCGGCAG
CCCGGGCCCGCATGGAGGCTCGCGGCGAGCAGCAGGCTGAGACTACTCAGCGCTTTTTTTCGGACATCTCTAACTATGGC
AACCAGTTCACTCGACAAGTCCAACAGCTTCGAGACCAAGCAACTAAGCATGGCGCCGATCCCCAAGAGCTGCGCAAGGA
TCTGAATCAACTGGTACACGACGGCCTGAAAGCCAATCCTTCGCTACTGAGCTTGTACGTGGTGTTCGCCCCTGATGCAT
TGGACGGCCAGGATGCGCGCTTTGCCGATGAATCTACCTCGGGCAGTAACGAGAAAGGCCGATTTGCTTCTTACTGGAGC
CAGAAGGATTCGACAGACAGTTACATGGCGGTGCCTGAGAAAATCATCGCCGATACAACCCCTATGTTGGACGGTACTCC
GTTCAATACCTGGTATAGCTGCCCACAGCAAACCCTCAGGCCTTGCGTGCTCAATCCTTATTTTGACGACACGTCTGGCC
AGCCTTTACTGATGACAACTCTTGCTTTTCCATTGATCGAAAATGGCAAAGTCATTGCGGTCATCGGCGCGGATATCAGC
CTGAGTCGATTGCAGCAGCTAAGTCTGGATGGCAGCCTGCAACTCTATGAGGGTAGGGGGACATTGCGAATCGTCAGTTC
CGCTGGATTGGTTGCGGGCGATAGCCATAATCCAGGTTCACTCGGTCGTACACTCGAAAGCGTTCAGAAGGATGGTGCTG
ACCTACTGGCGATGTTGAGCTCAGGTAAGTCTCAGTCCTTGGATACGCTCACGAGCCTGCGCATTTTGGAGCCGCTGAAG
GTGATTCCTGAGGGGAAACCTTGGGGATTGGTTTTAGAGGTTCCGCGAGCAATCCTGCTGGAACCGGCGCTTGCGCTGCA
TCAGGAACTTGATGAGCGAAGCCTGTCCGGTGCGCTATGGGAAACAGGGCTTGCGGGAGGCGTGGCGCTGCTAGGTCTGA
TCGTGCTGTGGTTGACTGCTCGCGGCGTCAGCATGCCAATCCTTAGCGTGGCCAACATGCTTCGGGATATCGCCAGCGGT
GAGGGTGATCTCACCAAACGTTTGGATTATCAAGGCAGCGATGAACTGGGTCAGTTAGCAGGTTGGTTTAATCGCTTTCT
AGACAAACTCCACCCGATAATCCGGGACGTGAAAGCGTCCGTGCATGATGCCCGCGCAACCGCAGATCAGTCAGCGACAT
TGTCTGAGCAAACCAGTACAGGGATGGAGCACCAGTTCAGGGAAATCGAACAGGTGGCCACCGCGTCGCAGGAAATGAGT
GCAACGGCCCATGATGTGGCCACTAGCGCGGCCCAGGCTGCGCAAGCGGCTCGTGGTGCAGAGCAGGCGAGCTCGGATGG
CCTGGCGGTGATACAACAAACTACGCATTTGATTGATGGCTTGGCCAAAGACATGAGTCTTGCGGTAAGAGAGGTCGAAG
GTTTGGCGGCCAGCAGCAGCAAGATTGGTTCTGTGCTGGACGTCATACGAGCGATCGCCGAGCAAACCAATCTGTTGGCC
CTGAACGCGGCCATTGAGGCTGCGCGGGCCGGTGATGCGGGTCGGGGATTTGCGGTTGTGGCCGACGAAGTGAGGGGGCT
GGCGAAACGAACCCAGGATTCGGTCGAAGAGGTCCGCCAGGTGATCGAGACGTTGCAGCGCGGTACGAGTGAGGTGGTCA
ACGCGATGAACAATAGCCACCATCAGGCCCAGGGGAGCGCGGGGCAGGTCGTGCAAGCCGTGACGGCACTGCAGCGTATC
AGCGGCGCGGTTTCCATCATCAATGACATGAACCTGCAGATCGCCAGCGCGGCCGAGGAGCAGAGTGTGGTGGCGGAGGA
GGTGAATCGAAATGTGGCATCGATTCGTGATGTCACCGAGTCGCTGTCTGATCAATCAAAAAAATCTGCTCAGATCAGTC
AGTCCTTGAACCATCTGGCCAATCATCAGCAGCAGTTGATGGCGCAGTTCAAAGTCTGA

Upstream 100 bases:

>100_bases
CTGGCTGAAGAGATGTGGTTCGCGCAGGAACATCAGTCAGTCATGTTGACCGATTGATTTGGCCCCACTAAAAAAATATC
CCGGGTACGGGGAGGTATCT

Downstream 100 bases:

>100_bases
TCATCAAGTGGGTGTACACTCGGATTGCGGGATGCTTGATCGTCAGTCCAAAGGGGACGTGTGGTTGCCGACGCGCCGTC
AAGCCTGGAGGCATTTACAT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MRFARVSIKWKITLLAGFCLLCTVVLLVGTSLYRMDTSLALVKSANSQMLEAAARARMEARGEQQAETTQRFFSDISNYG
NQFTRQVQQLRDQATKHGADPQELRKDLNQLVHDGLKANPSLLSLYVVFAPDALDGQDARFADESTSGSNEKGRFASYWS
QKDSTDSYMAVPEKIIADTTPMLDGTPFNTWYSCPQQTLRPCVLNPYFDDTSGQPLLMTTLAFPLIENGKVIAVIGADIS
LSRLQQLSLDGSLQLYEGRGTLRIVSSAGLVAGDSHNPGSLGRTLESVQKDGADLLAMLSSGKSQSLDTLTSLRILEPLK
VIPEGKPWGLVLEVPRAILLEPALALHQELDERSLSGALWETGLAGGVALLGLIVLWLTARGVSMPILSVANMLRDIASG
EGDLTKRLDYQGSDELGQLAGWFNRFLDKLHPIIRDVKASVHDARATADQSATLSEQTSTGMEHQFREIEQVATASQEMS
ATAHDVATSAAQAAQAARGAEQASSDGLAVIQQTTHLIDGLAKDMSLAVREVEGLAASSSKIGSVLDVIRAIAEQTNLLA
LNAAIEAARAGDAGRGFAVVADEVRGLAKRTQDSVEEVRQVIETLQRGTSEVVNAMNNSHHQAQGSAGQVVQAVTALQRI
SGAVSIINDMNLQIASAAEEQSVVAEEVNRNVASIRDVTESLSDQSKKSAQISQSLNHLANHQQQLMAQFKV

Sequences:

>Translated_712_residues
MRFARVSIKWKITLLAGFCLLCTVVLLVGTSLYRMDTSLALVKSANSQMLEAAARARMEARGEQQAETTQRFFSDISNYG
NQFTRQVQQLRDQATKHGADPQELRKDLNQLVHDGLKANPSLLSLYVVFAPDALDGQDARFADESTSGSNEKGRFASYWS
QKDSTDSYMAVPEKIIADTTPMLDGTPFNTWYSCPQQTLRPCVLNPYFDDTSGQPLLMTTLAFPLIENGKVIAVIGADIS
LSRLQQLSLDGSLQLYEGRGTLRIVSSAGLVAGDSHNPGSLGRTLESVQKDGADLLAMLSSGKSQSLDTLTSLRILEPLK
VIPEGKPWGLVLEVPRAILLEPALALHQELDERSLSGALWETGLAGGVALLGLIVLWLTARGVSMPILSVANMLRDIASG
EGDLTKRLDYQGSDELGQLAGWFNRFLDKLHPIIRDVKASVHDARATADQSATLSEQTSTGMEHQFREIEQVATASQEMS
ATAHDVATSAAQAAQAARGAEQASSDGLAVIQQTTHLIDGLAKDMSLAVREVEGLAASSSKIGSVLDVIRAIAEQTNLLA
LNAAIEAARAGDAGRGFAVVADEVRGLAKRTQDSVEEVRQVIETLQRGTSEVVNAMNNSHHQAQGSAGQVVQAVTALQRI
SGAVSIINDMNLQIASAAEEQSVVAEEVNRNVASIRDVTESLSDQSKKSAQISQSLNHLANHQQQLMAQFKV
>Mature_712_residues
MRFARVSIKWKITLLAGFCLLCTVVLLVGTSLYRMDTSLALVKSANSQMLEAAARARMEARGEQQAETTQRFFSDISNYG
NQFTRQVQQLRDQATKHGADPQELRKDLNQLVHDGLKANPSLLSLYVVFAPDALDGQDARFADESTSGSNEKGRFASYWS
QKDSTDSYMAVPEKIIADTTPMLDGTPFNTWYSCPQQTLRPCVLNPYFDDTSGQPLLMTTLAFPLIENGKVIAVIGADIS
LSRLQQLSLDGSLQLYEGRGTLRIVSSAGLVAGDSHNPGSLGRTLESVQKDGADLLAMLSSGKSQSLDTLTSLRILEPLK
VIPEGKPWGLVLEVPRAILLEPALALHQELDERSLSGALWETGLAGGVALLGLIVLWLTARGVSMPILSVANMLRDIASG
EGDLTKRLDYQGSDELGQLAGWFNRFLDKLHPIIRDVKASVHDARATADQSATLSEQTSTGMEHQFREIEQVATASQEMS
ATAHDVATSAAQAAQAARGAEQASSDGLAVIQQTTHLIDGLAKDMSLAVREVEGLAASSSKIGSVLDVIRAIAEQTNLLA
LNAAIEAARAGDAGRGFAVVADEVRGLAKRTQDSVEEVRQVIETLQRGTSEVVNAMNNSHHQAQGSAGQVVQAVTALQRI
SGAVSIINDMNLQIASAAEEQSVVAEEVNRNVASIRDVTESLSDQSKKSAQISQSLNHLANHQQQLMAQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=32.9305135951662, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788194, Length=335, Percent_Identity=28.955223880597, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=32.2033898305085, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1787690, Length=330, Percent_Identity=31.5151515151515, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=30.3468208092486, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76593; Mature: 76593

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFARVSIKWKITLLAGFCLLCTVVLLVGTSLYRMDTSLALVKSANSQMLEAAARARMEA
CCEEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RGEQQAETTQRFFSDISNYGNQFTRQVQQLRDQATKHGADPQELRKDLNQLVHDGLKANP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
SLLSLYVVFAPDALDGQDARFADESTSGSNEKGRFASYWSQKDSTDSYMAVPEKIIADTT
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHCCC
PMLDGTPFNTWYSCPQQTLRPCVLNPYFDDTSGQPLLMTTLAFPLIENGKVIAVIGADIS
CCCCCCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCC
LSRLQQLSLDGSLQLYEGRGTLRIVSSAGLVAGDSHNPGSLGRTLESVQKDGADLLAMLS
HHHHHHHCCCCCEEEEECCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHH
SGKSQSLDTLTSLRILEPLKVIPEGKPWGLVLEVPRAILLEPALALHQELDERSLSGALW
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETGLAGGVALLGLIVLWLTARGVSMPILSVANMLRDIASGEGDLTKRLDYQGSDELGQLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHH
GWFNRFLDKLHPIIRDVKASVHDARATADQSATLSEQTSTGMEHQFREIEQVATASQEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ATAHDVATSAAQAAQAARGAEQASSDGLAVIQQTTHLIDGLAKDMSLAVREVEGLAASSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KIGSVLDVIRAIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAKRTQDSVEEVRQ
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIETLQRGTSEVVNAMNNSHHQAQGSAGQVVQAVTALQRISGAVSIINDMNLQIASAAEE
HHHHHHHCHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
QSVVAEEVNRNVASIRDVTESLSDQSKKSAQISQSLNHLANHQQQLMAQFKV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFARVSIKWKITLLAGFCLLCTVVLLVGTSLYRMDTSLALVKSANSQMLEAAARARMEA
CCEEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RGEQQAETTQRFFSDISNYGNQFTRQVQQLRDQATKHGADPQELRKDLNQLVHDGLKANP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
SLLSLYVVFAPDALDGQDARFADESTSGSNEKGRFASYWSQKDSTDSYMAVPEKIIADTT
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHCCC
PMLDGTPFNTWYSCPQQTLRPCVLNPYFDDTSGQPLLMTTLAFPLIENGKVIAVIGADIS
CCCCCCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCC
LSRLQQLSLDGSLQLYEGRGTLRIVSSAGLVAGDSHNPGSLGRTLESVQKDGADLLAMLS
HHHHHHHCCCCCEEEEECCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHH
SGKSQSLDTLTSLRILEPLKVIPEGKPWGLVLEVPRAILLEPALALHQELDERSLSGALW
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETGLAGGVALLGLIVLWLTARGVSMPILSVANMLRDIASGEGDLTKRLDYQGSDELGQLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHH
GWFNRFLDKLHPIIRDVKASVHDARATADQSATLSEQTSTGMEHQFREIEQVATASQEMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ATAHDVATSAAQAAQAARGAEQASSDGLAVIQQTTHLIDGLAKDMSLAVREVEGLAASSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KIGSVLDVIRAIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAKRTQDSVEEVRQ
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIETLQRGTSEVVNAMNNSHHQAQGSAGQVVQAVTALQRISGAVSIINDMNLQIASAAEE
HHHHHHHCHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
QSVVAEEVNRNVASIRDVTESLSDQSKKSAQISQSLNHLANHQQQLMAQFKV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]