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The map label for this gene is yajO [H]

Identifier: 77459140

GI number: 77459140

Start: 3359984

End: 3360997

Strand: Direct

Name: yajO [H]

Synonym: Pfl01_2915

Alternate gene names: 77459140

Gene position: 3359984-3360997 (Clockwise)

Preceding gene: 77459139

Following gene: 77459141

Centisome position: 52.19

GC content: 62.62

Gene sequence:

>1014_bases
ATGAGCTATCGCACACTGGGTCACTCGGGGTTGCAAGTGTCCGCCCTCACCCTCGGCACGATGATGTTCGGCGAACAGAC
CAGCGCGGAAGACTCGCTGCGCATCATCGACAAGGCCTGGGATCAGGGCATCAACTTCATCGACACCGCCGACGTCTATA
CCAACGGCCGCTCGGAAGAGATCGTCGGCGAAGCCATCGCCCGTCATCGGCATGAATGGGTGCTGGCGACCAAAGTCGGT
TTCGGCCCCGTGGATGGCGTGCCGAACCGCAGCGGCTTGAGCCGCAAGCACATCTTCAATGGTCTGGAGGCCAGCCTGAC
CCGGCTCGGCACCGACTACCTCGACATCTATTACCTGCACCGCGAAGACCACAACACCCCGCTGGAAGTGACGATCTCGG
CGATTGGCGATCTGATTCGCCAGGGCAAGATCCGTTATTGGGGCCTGTCGAACTATCGCGGCTGGCGGATTGCCGAGGTG
ATCCGCGTGGCGGACAAACTCGGCGTCGATCGCCCGGTGATCAGCCAGCCGCTGTACAACATCGTCAACCGTCAGGCCGA
GACCGAGCAGATCACCGCCGCCCAGACTTACGGCCTCGGCGTCGTGCCTTACAGCCCGCTGGCCCGTGGCGTGCTCAGCG
GCAAGTACGCACCGGACGTGACCCCGGACGCCAACAGCCGGGCCGGGCGCCAGGACAAACGGATTCTGGAGACTGAATGG
CGCGTGGAATCGTTGCGCATTGCCCAGCAGATTCAGCAATACACCCGGGAGCGTGGGGTCGGGATTGTCGAGTTTGCGAT
TGCCTGGGTGCTGAACAACGGCGCGGTGACCTCGGCGATTGTCGGGCCGCGTACGGAAGAACAGTGGGATGCGTACACCA
AGGCGCAGGCGGTGAAGATCACGGCGGAGGATGAGGCGTTTATCGATTCGCTGGTGACGCCGGGGCATGCGTCTACGCCG
GGGTTTAATGATGTGAGCCATTTTGTGTCGGGCCGCAAACCGCGTTCGGCTTGA

Upstream 100 bases:

>100_bases
GCGCGAGCGCTGCGAGGCGTTGCGGCGATAAATTCACTTTGCCGCGCCGGGCGCTTCTGGTATTTGATGGAAGCTTTCCC
ACCGACAAAAGGATTTCGGC

Downstream 100 bases:

>100_bases
GACCGCTGCCCTCACCCTAGCCCTCTCCCGGAGGGAGAGGGAACCGATTGGGGGATATTGAAGCTAAGCTTTTGCCTGAA
GCTCTCGTGGTGAATCCACA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSYRTLGHSGLQVSALTLGTMMFGEQTSAEDSLRIIDKAWDQGINFIDTADVYTNGRSEEIVGEAIARHRHEWVLATKVG
FGPVDGVPNRSGLSRKHIFNGLEASLTRLGTDYLDIYYLHREDHNTPLEVTISAIGDLIRQGKIRYWGLSNYRGWRIAEV
IRVADKLGVDRPVISQPLYNIVNRQAETEQITAAQTYGLGVVPYSPLARGVLSGKYAPDVTPDANSRAGRQDKRILETEW
RVESLRIAQQIQQYTRERGVGIVEFAIAWVLNNGAVTSAIVGPRTEEQWDAYTKAQAVKITAEDEAFIDSLVTPGHASTP
GFNDVSHFVSGRKPRSA

Sequences:

>Translated_337_residues
MSYRTLGHSGLQVSALTLGTMMFGEQTSAEDSLRIIDKAWDQGINFIDTADVYTNGRSEEIVGEAIARHRHEWVLATKVG
FGPVDGVPNRSGLSRKHIFNGLEASLTRLGTDYLDIYYLHREDHNTPLEVTISAIGDLIRQGKIRYWGLSNYRGWRIAEV
IRVADKLGVDRPVISQPLYNIVNRQAETEQITAAQTYGLGVVPYSPLARGVLSGKYAPDVTPDANSRAGRQDKRILETEW
RVESLRIAQQIQQYTRERGVGIVEFAIAWVLNNGAVTSAIVGPRTEEQWDAYTKAQAVKITAEDEAFIDSLVTPGHASTP
GFNDVSHFVSGRKPRSA
>Mature_336_residues
SYRTLGHSGLQVSALTLGTMMFGEQTSAEDSLRIIDKAWDQGINFIDTADVYTNGRSEEIVGEAIARHRHEWVLATKVGF
GPVDGVPNRSGLSRKHIFNGLEASLTRLGTDYLDIYYLHREDHNTPLEVTISAIGDLIRQGKIRYWGLSNYRGWRIAEVI
RVADKLGVDRPVISQPLYNIVNRQAETEQITAAQTYGLGVVPYSPLARGVLSGKYAPDVTPDANSRAGRQDKRILETEWR
VESLRIAQQIQQYTRERGVGIVEFAIAWVLNNGAVTSAIVGPRTEEQWDAYTKAQAVKITAEDEAFIDSLVTPGHASTPG
FNDVSHFVSGRKPRSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=296, Percent_Identity=36.4864864864865, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4504825, Length=294, Percent_Identity=36.3945578231293, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI27436962, Length=298, Percent_Identity=36.5771812080537, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI27436964, Length=298, Percent_Identity=36.5771812080537, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI27436966, Length=298, Percent_Identity=36.241610738255, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=32.8173374613003, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI223718702, Length=230, Percent_Identity=33.4782608695652, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI41327764, Length=205, Percent_Identity=36.0975609756098, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI41152114, Length=203, Percent_Identity=34.9753694581281, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI223718708, Length=167, Percent_Identity=33.5329341317365, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=36.3076923076923, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=33.6363636363636, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=31.3953488372093, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=28.7461773700306, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788081, Length=212, Percent_Identity=33.0188679245283, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787674, Length=212, Percent_Identity=25.9433962264151, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI48994888, Length=155, Percent_Identity=29.6774193548387, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=300, Percent_Identity=25.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=32.4483775811209, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=25.9259259259259, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.6756756756757, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=226, Percent_Identity=24.3362831858407, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=31.2883435582822, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=316, Percent_Identity=26.2658227848101, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45549126, Length=316, Percent_Identity=26.2658227848101, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646155, Length=296, Percent_Identity=26.3513513513513, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37368; Mature: 37237

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRTLGHSGLQVSALTLGTMMFGEQTSAEDSLRIIDKAWDQGINFIDTADVYTNGRSEE
CCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCHHHCCCCCHH
IVGEAIARHRHEWVLATKVGFGPVDGVPNRSGLSRKHIFNGLEASLTRLGTDYLDIYYLH
HHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
REDHNTPLEVTISAIGDLIRQGKIRYWGLSNYRGWRIAEVIRVADKLGVDRPVISQPLYN
ECCCCCCCEEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
IVNRQAETEQITAAQTYGLGVVPYSPLARGVLSGKYAPDVTPDANSRAGRQDKRILETEW
HHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RVESLRIAQQIQQYTRERGVGIVEFAIAWVLNNGAVTSAIVGPRTEEQWDAYTKAQAVKI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEHCCCCCCHHHHHHHHHCEEEEE
TAEDEAFIDSLVTPGHASTPGFNDVSHFVSGRKPRSA
EECHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYRTLGHSGLQVSALTLGTMMFGEQTSAEDSLRIIDKAWDQGINFIDTADVYTNGRSEE
CCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCHHHCCCCCHH
IVGEAIARHRHEWVLATKVGFGPVDGVPNRSGLSRKHIFNGLEASLTRLGTDYLDIYYLH
HHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
REDHNTPLEVTISAIGDLIRQGKIRYWGLSNYRGWRIAEVIRVADKLGVDRPVISQPLYN
ECCCCCCCEEEHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
IVNRQAETEQITAAQTYGLGVVPYSPLARGVLSGKYAPDVTPDANSRAGRQDKRILETEW
HHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RVESLRIAQQIQQYTRERGVGIVEFAIAWVLNNGAVTSAIVGPRTEEQWDAYTKAQAVKI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEHCCCCCCHHHHHHHHHCEEEEE
TAEDEAFIDSLVTPGHASTPGFNDVSHFVSGRKPRSA
EECHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]