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The map label for this gene is yafC [H]

Identifier: 77459139

GI number: 77459139

Start: 3359015

End: 3359914

Strand: Direct

Name: yafC [H]

Synonym: Pfl01_2914

Alternate gene names: 77459139

Gene position: 3359015-3359914 (Clockwise)

Preceding gene: 77459135

Following gene: 77459140

Centisome position: 52.17

GC content: 65.89

Gene sequence:

>900_bases
ATGAGCTCGATTCTCGATCTTGAGATCTTCGTCCGTACCGCCGACTCCGGCAGCATTTCCGCCGCCGCCCGGGCGCTGGA
GTTGACACCGGCCGCCGCCAGCATCGCGCTGAAACGCCTGGAAACCCGCCTCGGCATTCGCCTGTTCGCCCGCTCGACGC
GCAGCATGCGCCTGACCGAAGAAGGTCGGCGCTATCTGGAAAGCGTGCGCCTGGCACTGGCCACATTGGCCGAGGGCGAA
CAGGCGCTGAAGCAACAGACCGAAGGCCTGAGCGGCGTGTTGCAACTGGCGGCGCCGTCGGACTTCGGGCGCAACGTGCT
GCTGCCGTGGCTGGACGATTTCAAGCGCGAGCACCCGCACATTCAACTGCAATTGCTGCTCAACGACCGGCATGCGGATC
TGTTTCGCGAGACGGTGGATGTGGCGCTGCGCTTTGGCGTGCCGAGTGATTCGACGCTGGTGGCGTTGCCGATTCTGCCT
GAGCATCGCCGCGTGGCCTGCGCCAGTCCTGCGTATATCGAGCGCCACGGTACACCGCAAAATCCTGCCGAATTGAGCGA
GCACGGCGCCCTGCTCTACCTGCGCAACGGCCGTCCCTACAACACCTGGCGCTTCCATCGCGAGGACGAAACGGTCGAGG
TCGAAGTGCGCGGCGACTACCTCAGCGACGACGGCGAAGTCGCCCGCCGCTGGGCGCTGGCCGGGCACGGCATCGCCTAC
AAGGCCTGGCTCGACGTGGCCGAAGACGTGCGTGCCGGGCGGCTGCTGACGCTATTCGATGACTGGCTGGGCGAGAGCGT
GCCGTTCAATCTGCTGTGCCCGCACCGGGTGCAGGTGTCGGAGCGGGTCAAGGTGTTGCAGGCGTTTTTGCGCGAGCGCT
GCGAGGCGTTGCGGCGATAA

Upstream 100 bases:

>100_bases
TGAGAGTTCTCCGGTGGGCTTGAGGAGATTGCATCTTCCCCGGTTGCCAATCGCAGAAAAATCCCGGTAAATCGGAAGGA
TCTTTAAAGGATTTTTACCA

Downstream 100 bases:

>100_bases
ATTCACTTTGCCGCGCCGGGCGCTTCTGGTATTTGATGGAAGCTTTCCCACCGACAAAAGGATTTCGGCATGAGCTATCG
CACACTGGGTCACTCGGGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSSILDLEIFVRTADSGSISAAARALELTPAAASIALKRLETRLGIRLFARSTRSMRLTEEGRRYLESVRLALATLAEGE
QALKQQTEGLSGVLQLAAPSDFGRNVLLPWLDDFKREHPHIQLQLLLNDRHADLFRETVDVALRFGVPSDSTLVALPILP
EHRRVACASPAYIERHGTPQNPAELSEHGALLYLRNGRPYNTWRFHREDETVEVEVRGDYLSDDGEVARRWALAGHGIAY
KAWLDVAEDVRAGRLLTLFDDWLGESVPFNLLCPHRVQVSERVKVLQAFLRERCEALRR

Sequences:

>Translated_299_residues
MSSILDLEIFVRTADSGSISAAARALELTPAAASIALKRLETRLGIRLFARSTRSMRLTEEGRRYLESVRLALATLAEGE
QALKQQTEGLSGVLQLAAPSDFGRNVLLPWLDDFKREHPHIQLQLLLNDRHADLFRETVDVALRFGVPSDSTLVALPILP
EHRRVACASPAYIERHGTPQNPAELSEHGALLYLRNGRPYNTWRFHREDETVEVEVRGDYLSDDGEVARRWALAGHGIAY
KAWLDVAEDVRAGRLLTLFDDWLGESVPFNLLCPHRVQVSERVKVLQAFLRERCEALRR
>Mature_298_residues
SSILDLEIFVRTADSGSISAAARALELTPAAASIALKRLETRLGIRLFARSTRSMRLTEEGRRYLESVRLALATLAEGEQ
ALKQQTEGLSGVLQLAAPSDFGRNVLLPWLDDFKREHPHIQLQLLLNDRHADLFRETVDVALRFGVPSDSTLVALPILPE
HRRVACASPAYIERHGTPQNPAELSEHGALLYLRNGRPYNTWRFHREDETVEVEVRGDYLSDDGEVARRWALAGHGIAYK
AWLDVAEDVRAGRLLTLFDDWLGESVPFNLLCPHRVQVSERVKVLQAFLRERCEALRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=32.9861111111111, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=29.757785467128, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=28.7162162162162, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=29.4314381270903, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=28.8135593220339, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=29.5620437956204, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789639, Length=283, Percent_Identity=28.9752650176678, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789173, Length=267, Percent_Identity=28.4644194756554, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=28.957528957529, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786448, Length=175, Percent_Identity=34.2857142857143, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=158, Percent_Identity=31.6455696202532, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=266, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=124, Percent_Identity=32.258064516129, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33733; Mature: 33602

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSILDLEIFVRTADSGSISAAARALELTPAAASIALKRLETRLGIRLFARSTRSMRLTE
CCCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEHH
EGRRYLESVRLALATLAEGEQALKQQTEGLSGVLQLAAPSDFGRNVLLPWLDDFKREHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEECCCHHHHCCCCCC
IQLQLLLNDRHADLFRETVDVALRFGVPSDSTLVALPILPEHRRVACASPAYIERHGTPQ
EEEEEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEECCCHHHHCCCCCC
NPAELSEHGALLYLRNGRPYNTWRFHREDETVEVEVRGDYLSDDGEVARRWALAGHGIAY
CHHHHHHCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEH
KAWLDVAEDVRAGRLLTLFDDWLGESVPFNLLCPHRVQVSERVKVLQAFLRERCEALRR
HHHHHHHHHHCCCCEEEHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSILDLEIFVRTADSGSISAAARALELTPAAASIALKRLETRLGIRLFARSTRSMRLTE
CCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEHH
EGRRYLESVRLALATLAEGEQALKQQTEGLSGVLQLAAPSDFGRNVLLPWLDDFKREHPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEECCCHHHHCCCCCC
IQLQLLLNDRHADLFRETVDVALRFGVPSDSTLVALPILPEHRRVACASPAYIERHGTPQ
EEEEEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEECCCHHHHCCCCCC
NPAELSEHGALLYLRNGRPYNTWRFHREDETVEVEVRGDYLSDDGEVARRWALAGHGIAY
CHHHHHHCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEH
KAWLDVAEDVRAGRLLTLFDDWLGESVPFNLLCPHRVQVSERVKVLQAFLRERCEALRR
HHHHHHHHHHCCCCEEEHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]