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The map label for this gene is hlyB [H]

Identifier: 77459132

GI number: 77459132

Start: 3351191

End: 3352816

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_2907

Alternate gene names: 77459132

Gene position: 3352816-3351191 (Counterclockwise)

Preceding gene: 77459133

Following gene: 77459130

Centisome position: 52.08

GC content: 62.12

Gene sequence:

>1626_bases
ATGTCCTTGCGTAATCTGAATATCGCGCCCCGTGCCTTCCTCGGTTTTGCCTTTATTGCCTTGCTGGTGATTGTGCTCGG
CGTGTTCGCCGTCAACCGCATGTCGATCATCCGTCAGGCTTCCCTGGAGATGGACTCTACGCAGTTGCCAAGCGTCACCC
AACTCGCGGTGGTGACGGAGAACGTGCTGCGCCTGCGGATTCTCTCGTTCCGCATTCTGGTCAACCGCGACCCGGCCGGT
TTGCAGGAAGCCCAGACCCGCATCGGTGTGCTGGTGGACAAGGTGCGCACTGCTCAGGCCAGTTACGCGGCATTGCCGGC
CGGTCCGCAAGAGCGCGCGTTATATCAGGAGTTCTCGACGACCCTCGACAACTACGTGCAGGCGCAAAACCAGATGATGG
AGCTGTCGCGCCAGGACAAACTCGACGAGATGCGCGCCCTGATCAATACGAAGATCAAGGACGGCACCGACAAGATGGGC
GAACAACTCAACAAGCTGATCGCGATCAACGCCGCCGACGCGAAGACCGCTTCCACTCAGGCGGGTGAGTATTACAACAG
TGCCATTACCGGCATCATCGCCGTGTCTGTGATTGCCGCGTTGTTGACCGTATTGCTGGCCTGGCTGCTGACCCGCAGCA
TCGTCACGCCGCTGAACCGCGCCGTCGCTGCCGCGCAAACCATCGCTGGCGGCAACCTGACCAAAGCCATCGAAGTCGAC
GGCAAGGACGAGCCGGCGCGCCTGCTTGAAGCCTTGGCCGCGATGCAGACCAACCTGCGCAAGACCATCGAGCAGATTGC
CGGCTCCGCCACCCAACTGGGCGCCGCCGCCGAAGAACTCAGCGCGGTGATCGAAGAGGCCTCCCGTGGCCTGCAACAGC
AGAACGATGAAATCGAACAGGCCGCCACCGCCGTCAACGAAATGACCGCTGCGGTGGAAGAGGTGGCACGCAACGCAGTG
TCGACCTCCGAAGCCTCGAACCAGTCGACCCACGCCGCCCGTGAAGGTCGCGATCAGGTGGTGAAAACCGTCGACGCGAT
CCAGACCATGACCCACGACGTGCAAAACACCGCGCAAATGATCGAAGGCCTGGCCGCTCAGGGCCGCGACATCGGCAAAG
TGCTGGACGTGATCCGCGCCATCGCCGAACAGACCAACCTGCTGGCGCTCAACGCCGCCATCGAAGCAGCCCGTGCCGGT
GAAGCGGGACGTGGTTTTGCCGTGGTAGCGGATGAAGTTCGCGCCCTGGCCCATCGCACCGCGCAATCGACCCAGGAGAT
CGAAAAAATGGTCGCCGGCATTCAGAACGGCACCGGTGAAGCAGTCGAGTCGATGCAGCAAAGTAACCAGCGCACCCAGA
CCACCCTGGAAATGGCCCGCGCCGCCGGCGTCGCACTGGAGCAGATCACTCAATCGATTCACCAGATCAACGAGCGCAAC
CTGGTGATCGCCAGCGCCTCGGAAGAGCAGGCGCAGGTGTCCCGTGAGGTCGACCGCAACCTGGTCAACATCCGCGACCT
GGCCACTCAATCGGCCGCCGGCGCGAATCAAACCAGCGCCGCGACTCACGAACTGTCGCGCCTGGCGGTGGATTTGAATG
CGATGGTGGCGCGCTTTGTGATTTGA

Upstream 100 bases:

>100_bases
ACAAGATTTTCCAGAACAGTGACGCCGGACTGACGCCCACTCCAAGGGCCAGTGATCACGGCATGGACGCTCGTAGTTTC
AATCATCCGAGAGTCCTCCT

Downstream 100 bases:

>100_bases
AATGACGGGCTCGGATATCGAGCCCGACGATTGGTTTTAGGGAATTAGCACCGTTACCCGTGCAGGATGTGATCGCGGGC
TTCGAGACCCGTCTGGGAAC

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSLRNLNIAPRAFLGFAFIALLVIVLGVFAVNRMSIIRQASLEMDSTQLPSVTQLAVVTENVLRLRILSFRILVNRDPAG
LQEAQTRIGVLVDKVRTAQASYAALPAGPQERALYQEFSTTLDNYVQAQNQMMELSRQDKLDEMRALINTKIKDGTDKMG
EQLNKLIAINAADAKTASTQAGEYYNSAITGIIAVSVIAALLTVLLAWLLTRSIVTPLNRAVAAAQTIAGGNLTKAIEVD
GKDEPARLLEALAAMQTNLRKTIEQIAGSATQLGAAAEELSAVIEEASRGLQQQNDEIEQAATAVNEMTAAVEEVARNAV
STSEASNQSTHAAREGRDQVVKTVDAIQTMTHDVQNTAQMIEGLAAQGRDIGKVLDVIRAIAEQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTAQSTQEIEKMVAGIQNGTGEAVESMQQSNQRTQTTLEMARAAGVALEQITQSIHQINERN
LVIASASEEQAQVSREVDRNLVNIRDLATQSAAGANQTSAATHELSRLAVDLNAMVARFVI

Sequences:

>Translated_541_residues
MSLRNLNIAPRAFLGFAFIALLVIVLGVFAVNRMSIIRQASLEMDSTQLPSVTQLAVVTENVLRLRILSFRILVNRDPAG
LQEAQTRIGVLVDKVRTAQASYAALPAGPQERALYQEFSTTLDNYVQAQNQMMELSRQDKLDEMRALINTKIKDGTDKMG
EQLNKLIAINAADAKTASTQAGEYYNSAITGIIAVSVIAALLTVLLAWLLTRSIVTPLNRAVAAAQTIAGGNLTKAIEVD
GKDEPARLLEALAAMQTNLRKTIEQIAGSATQLGAAAEELSAVIEEASRGLQQQNDEIEQAATAVNEMTAAVEEVARNAV
STSEASNQSTHAAREGRDQVVKTVDAIQTMTHDVQNTAQMIEGLAAQGRDIGKVLDVIRAIAEQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTAQSTQEIEKMVAGIQNGTGEAVESMQQSNQRTQTTLEMARAAGVALEQITQSIHQINERN
LVIASASEEQAQVSREVDRNLVNIRDLATQSAAGANQTSAATHELSRLAVDLNAMVARFVI
>Mature_540_residues
SLRNLNIAPRAFLGFAFIALLVIVLGVFAVNRMSIIRQASLEMDSTQLPSVTQLAVVTENVLRLRILSFRILVNRDPAGL
QEAQTRIGVLVDKVRTAQASYAALPAGPQERALYQEFSTTLDNYVQAQNQMMELSRQDKLDEMRALINTKIKDGTDKMGE
QLNKLIAINAADAKTASTQAGEYYNSAITGIIAVSVIAALLTVLLAWLLTRSIVTPLNRAVAAAQTIAGGNLTKAIEVDG
KDEPARLLEALAAMQTNLRKTIEQIAGSATQLGAAAEELSAVIEEASRGLQQQNDEIEQAATAVNEMTAAVEEVARNAVS
TSEASNQSTHAAREGRDQVVKTVDAIQTMTHDVQNTAQMIEGLAAQGRDIGKVLDVIRAIAEQTNLLALNAAIEAARAGE
AGRGFAVVADEVRALAHRTAQSTQEIEKMVAGIQNGTGEAVESMQQSNQRTQTTLEMARAAGVALEQITQSIHQINERNL
VIASASEEQAQVSREVDRNLVNIRDLATQSAAGANQTSAATHELSRLAVDLNAMVARFVI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=407, Percent_Identity=33.1695331695332, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788194, Length=365, Percent_Identity=32.3287671232877, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788195, Length=293, Percent_Identity=32.7645051194539, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787690, Length=434, Percent_Identity=29.0322580645161, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789453, Length=347, Percent_Identity=28.8184438040346, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57963; Mature: 57831

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRNLNIAPRAFLGFAFIALLVIVLGVFAVNRMSIIRQASLEMDSTQLPSVTQLAVVTE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
NVLRLRILSFRILVNRDPAGLQEAQTRIGVLVDKVRTAQASYAALPAGPQERALYQEFST
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TLDNYVQAQNQMMELSRQDKLDEMRALINTKIKDGTDKMGEQLNKLIAINAADAKTASTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCCCCCCCHH
AGEYYNSAITGIIAVSVIAALLTVLLAWLLTRSIVTPLNRAVAAAQTIAGGNLTKAIEVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GKDEPARLLEALAAMQTNLRKTIEQIAGSATQLGAAAEELSAVIEEASRGLQQQNDEIEQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATAVNEMTAAVEEVARNAVSTSEASNQSTHAAREGRDQVVKTVDAIQTMTHDVQNTAQM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLAAQGRDIGKVLDVIRAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAHRT
HHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQSTQEIEKMVAGIQNGTGEAVESMQQSNQRTQTTLEMARAAGVALEQITQSIHQINERN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LVIASASEEQAQVSREVDRNLVNIRDLATQSAAGANQTSAATHELSRLAVDLNAMVARFV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
I
C
>Mature Secondary Structure 
SLRNLNIAPRAFLGFAFIALLVIVLGVFAVNRMSIIRQASLEMDSTQLPSVTQLAVVTE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
NVLRLRILSFRILVNRDPAGLQEAQTRIGVLVDKVRTAQASYAALPAGPQERALYQEFST
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TLDNYVQAQNQMMELSRQDKLDEMRALINTKIKDGTDKMGEQLNKLIAINAADAKTASTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCCCCCCCHH
AGEYYNSAITGIIAVSVIAALLTVLLAWLLTRSIVTPLNRAVAAAQTIAGGNLTKAIEVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GKDEPARLLEALAAMQTNLRKTIEQIAGSATQLGAAAEELSAVIEEASRGLQQQNDEIEQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATAVNEMTAAVEEVARNAVSTSEASNQSTHAAREGRDQVVKTVDAIQTMTHDVQNTAQM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLAAQGRDIGKVLDVIRAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAHRT
HHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQSTQEIEKMVAGIQNGTGEAVESMQQSNQRTQTTLEMARAAGVALEQITQSIHQINERN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LVIASASEEQAQVSREVDRNLVNIRDLATQSAAGANQTSAATHELSRLAVDLNAMVARFV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]