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The map label for this gene is aspC [H]

Identifier: 77459130

GI number: 77459130

Start: 3349371

End: 3350558

Strand: Reverse

Name: aspC [H]

Synonym: Pfl01_2905

Alternate gene names: 77459130

Gene position: 3350558-3349371 (Counterclockwise)

Preceding gene: 77459132

Following gene: 77459124

Centisome position: 52.04

GC content: 62.54

Gene sequence:

>1188_bases
ATGCGCTATTCAGCCTTGACCCAACGAATCGCCGGGGAGGGAGCAGCGGCCTGGCGGATTCACGACCGAGCGCTGGAGCT
GCGCGCCGAGGGCATTGATGTCTTGCTGCTGTCCGTGGGCGATCCGGATTTTGATACGCCGCTGCCGATCATCCATGGCG
CCATCGACAGCCTGTTGGCGGGCGATACGCATTATTCCGAAGTGCGCGGCCGACTGGAGCTGCGCAAGCGGATTGCCGAG
CGCCATCGGCGCAGCAGCGGTCAGGACGTCGATGCCGAGCATGTGATCGTGTTGCCCGGCGCGCAATGCGCGGTGTATTC
GGTGGCGCAGTGTCTGCTGGATCCGGATGATGAGGTGATCGTCGCCGAACCGATGTACGTGACTTATGAAGGCGTGTTTG
GTGCCTGTGGTGCAACCGTGGTGCCGGTGCCGGTACGGCCGGAAAACGGCTTTCGCGTCGATCCGGTGGACGTTGCGGCG
CGAATCACCTCAAAGACTCGGGCCATGTTGCTCAACAGTCCCAATAATCCTTCCGGCGCCAGTCTGTCGCTGTTGATCTG
GCAGGAGCTGGCGGCGCTGTGTATCCGTCATGACCTGTGGCTGATCAGCGATGAGGTCTACAGCGAATTGTTATACGAAG
GCGAGCACGTCAGCCCGGCAAGCCTGCCGGGCATGGCCGAGCGCACCGCGACCATCAACAGCTTGTCCAAATCCCACGCC
ATGACCGGGTGGCGCATCGGCTGGATGATCGGACCGAAACCCTTGGCCGAACATCTGGTGAATCTTTCGCTGAGCATGCT
GTTCGGCCTGCCGGATTTTGTGCAGAAGGCCGCGCAGGTCGCACTGGAAAAGGATCTGCCGGAAGTGACGCAAATGCGCG
AGGAATACCGCTTGCGCCGGGATCTGGTGTGCGAACGGTTGCGCGGCTGTCCGGGGTTGTACCCGATCAAGCCGGATGGC
GGGATGTTCGTGATGGTTGATGTACGTCAGACCGGGCTCGGTGCGCAGGACTTTGCCGAGCGGTTGCTGGAGGGCTATGG
GGTTTCGGTGCTGGCCGGTGAAGCGTTCGGGCCCAGTGCGGCGGGGCATATTCGCATCGGGTTGGTGGTGGATCGGGTGA
AGCTGGCGGATGCGTGTTCGCGGATTGCGCTGTGCGCTGCGCAGCTTCTCCAGGTGCGCAGCGCCTGA

Upstream 100 bases:

>100_bases
GAGTTTCATCGCATCCGCTGGAAGGAGGGAGCGCGATGGTGGCGCGCTTCGTGATTTGACCTAGGGTGAAGGCTGGAGAC
CGCGCAATCAGGAGACGTAC

Downstream 100 bases:

>100_bases
CCAAGATCAGAGTGGGGGATTCACCAGATTGGCGGGCCTTTGTCCCGCCAGCGCCGCCAACAGATTCTCCACCGCACACC
GCGCCATCGCTTCGCGCGTT

Product: L-aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MRYSALTQRIAGEGAAAWRIHDRALELRAEGIDVLLLSVGDPDFDTPLPIIHGAIDSLLAGDTHYSEVRGRLELRKRIAE
RHRRSSGQDVDAEHVIVLPGAQCAVYSVAQCLLDPDDEVIVAEPMYVTYEGVFGACGATVVPVPVRPENGFRVDPVDVAA
RITSKTRAMLLNSPNNPSGASLSLLIWQELAALCIRHDLWLISDEVYSELLYEGEHVSPASLPGMAERTATINSLSKSHA
MTGWRIGWMIGPKPLAEHLVNLSLSMLFGLPDFVQKAAQVALEKDLPEVTQMREEYRLRRDLVCERLRGCPGLYPIKPDG
GMFVMVDVRQTGLGAQDFAERLLEGYGVSVLAGEAFGPSAAGHIRIGLVVDRVKLADACSRIALCAAQLLQVRSA

Sequences:

>Translated_395_residues
MRYSALTQRIAGEGAAAWRIHDRALELRAEGIDVLLLSVGDPDFDTPLPIIHGAIDSLLAGDTHYSEVRGRLELRKRIAE
RHRRSSGQDVDAEHVIVLPGAQCAVYSVAQCLLDPDDEVIVAEPMYVTYEGVFGACGATVVPVPVRPENGFRVDPVDVAA
RITSKTRAMLLNSPNNPSGASLSLLIWQELAALCIRHDLWLISDEVYSELLYEGEHVSPASLPGMAERTATINSLSKSHA
MTGWRIGWMIGPKPLAEHLVNLSLSMLFGLPDFVQKAAQVALEKDLPEVTQMREEYRLRRDLVCERLRGCPGLYPIKPDG
GMFVMVDVRQTGLGAQDFAERLLEGYGVSVLAGEAFGPSAAGHIRIGLVVDRVKLADACSRIALCAAQLLQVRSA
>Mature_395_residues
MRYSALTQRIAGEGAAAWRIHDRALELRAEGIDVLLLSVGDPDFDTPLPIIHGAIDSLLAGDTHYSEVRGRLELRKRIAE
RHRRSSGQDVDAEHVIVLPGAQCAVYSVAQCLLDPDDEVIVAEPMYVTYEGVFGACGATVVPVPVRPENGFRVDPVDVAA
RITSKTRAMLLNSPNNPSGASLSLLIWQELAALCIRHDLWLISDEVYSELLYEGEHVSPASLPGMAERTATINSLSKSHA
MTGWRIGWMIGPKPLAEHLVNLSLSMLFGLPDFVQKAAQVALEKDLPEVTQMREEYRLRRDLVCERLRGCPGLYPIKPDG
GMFVMVDVRQTGLGAQDFAERLLEGYGVSVLAGEAFGPSAAGHIRIGLVVDRVKLADACSRIALCAAQLLQVRSA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=318, Percent_Identity=33.9622641509434, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI169881279, Length=318, Percent_Identity=33.9622641509434, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI56713254, Length=346, Percent_Identity=32.9479768786127, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI56713256, Length=346, Percent_Identity=32.9479768786127, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI169881281, Length=228, Percent_Identity=35.0877192982456, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4507369, Length=363, Percent_Identity=25.8953168044077, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=30.3030303030303, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=28.021978021978, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788627, Length=371, Percent_Identity=28.3018867924528, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1790797, Length=319, Percent_Identity=25.3918495297806, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787909, Length=350, Percent_Identity=22.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=344, Percent_Identity=28.4883720930233, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=344, Percent_Identity=28.4883720930233, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=329, Percent_Identity=26.7477203647416, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=26.4150943396226, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=360, Percent_Identity=27.7777777777778, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=356, Percent_Identity=22.752808988764, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573069, Length=342, Percent_Identity=27.1929824561404, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646114, Length=342, Percent_Identity=27.1929824561404, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573067, Length=342, Percent_Identity=27.1929824561404, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573065, Length=342, Percent_Identity=27.1929824561404, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=26.4705882352941, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43049; Mature: 43049

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSALTQRIAGEGAAAWRIHDRALELRAEGIDVLLLSVGDPDFDTPLPIIHGAIDSLLA
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHC
GDTHYSEVRGRLELRKRIAERHRRSSGQDVDAEHVIVLPGAQCAVYSVAQCLLDPDDEVI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEE
VAEPMYVTYEGVFGACGATVVPVPVRPENGFRVDPVDVAARITSKTRAMLLNSPNNPSGA
EECCEEEEECCHHHCCCCEEEEEECCCCCCCEECHHHHHHHHHHHHHEEEEECCCCCCCC
SLSLLIWQELAALCIRHDLWLISDEVYSELLYEGEHVSPASLPGMAERTATINSLSKSHA
EEHHHHHHHHHHHHHHHHHHEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
MTGWRIGWMIGPKPLAEHLVNLSLSMLFGLPDFVQKAAQVALEKDLPEVTQMREEYRLRR
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DLVCERLRGCPGLYPIKPDGGMFVMVDVRQTGLGAQDFAERLLEGYGVSVLAGEAFGPSA
HHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
AGHIRIGLVVDRVKLADACSRIALCAAQLLQVRSA
CCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYSALTQRIAGEGAAAWRIHDRALELRAEGIDVLLLSVGDPDFDTPLPIIHGAIDSLLA
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHC
GDTHYSEVRGRLELRKRIAERHRRSSGQDVDAEHVIVLPGAQCAVYSVAQCLLDPDDEVI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEE
VAEPMYVTYEGVFGACGATVVPVPVRPENGFRVDPVDVAARITSKTRAMLLNSPNNPSGA
EECCEEEEECCHHHCCCCEEEEEECCCCCCCEECHHHHHHHHHHHHHEEEEECCCCCCCC
SLSLLIWQELAALCIRHDLWLISDEVYSELLYEGEHVSPASLPGMAERTATINSLSKSHA
EEHHHHHHHHHHHHHHHHHHEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
MTGWRIGWMIGPKPLAEHLVNLSLSMLFGLPDFVQKAAQVALEKDLPEVTQMREEYRLRR
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DLVCERLRGCPGLYPIKPDGGMFVMVDVRQTGLGAQDFAERLLEGYGVSVLAGEAFGPSA
HHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
AGHIRIGLVVDRVKLADACSRIALCAAQLLQVRSA
CCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8907187; 10029535 [H]