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The map label for this gene is arnA [H]

Identifier: 77459068

GI number: 77459068

Start: 3280042

End: 3282048

Strand: Direct

Name: arnA [H]

Synonym: Pfl01_2843

Alternate gene names: 77459068

Gene position: 3280042-3282048 (Clockwise)

Preceding gene: 77459067

Following gene: 77459069

Centisome position: 50.94

GC content: 62.58

Gene sequence:

>2007_bases
ATGAGCGCAAAAACCGTTGTCTTCGCTTACCACGATATTGGCTGCGCCGGCATTCAAGCCCTGCTCGACAGTGGCTATGA
CATTGCGGCGGTGTTTACCCATGCCCATGACCCCAAGGAGAACACCTTCTACGCCTCGGTCGCGCAACTGTGCGCCAACA
ACGGCATCGCGGTTCATGCACCGGAAGACGCCAACCATCCGCTGTGGATCGAGCGGATCGCCAAGCTCGATCCGGATTAC
ATCTTCTCGTTCTACTATCGCAACCTGCTGAGCGAGCCGCTGCTGGCGCTGGCCAAAAAAGGCGCGTTCAACCTGCACGG
CTCCTTGTTGCCGCGCTACCGTGGCCGCGCTCCGGCCAACTGGGTGCTGGTCAACGGCGAAACCGAAACCGGTGTCACCC
TGCACCGCATGGTCAAACGCGCCGACGCCGGCGCCATCGTCGCCCAACAACGTGTAGCCATCGAACGCAGCGACACCGCG
CTGAGCCTGCACGGCAAACTGCGCACGGCCGCCAGCGACCTGCTGCGCGACGCGCTGCCAGCGATGCTTCAGGGCAGAAT
CACCGAGACCCCGCAAGACGAATCCAAAGCCACCGTGTTCGGTCGCCGTACCCCGGCGGACGGCAAACTGGTCTGGGCGC
AACCGGCCGAAAAACTGTTCAACCTGGTGCGGGCCGTGACTCAGCCCTACCCCGGCGCCTTCTGCGCCGTGGGCGAGCAC
AAGCTGATCGTCTGGAGTGCCGAAGTCGTCAAGGGCAACGAAGGTCAGGCGCCGGGCCGCGTCATCAGTGTCGATCCGCT
GCGCATCGCCTGCGGTGAAGACTCGCTGGTGATCAACGCCGGCCAGCGCAACGACAACGGCCTGTACCTCAGCGGCCCGC
AACTGGCCAATGAACTCGGTCTGGTGGACGGTTCGCTGCTGCGCGGTGCCGAGTCCGGCCGTGGCCCGCGCCGCACACGG
GTGCTGATCCTCGGCGTCAACGGTTTCATCGGCAACCATCTGTCCGAGCGCCTGCTGCGTGACGAGCGCTACGAAGTCTA
TGGCCTGGACATCGGTTCCGACGCCATCGACCGCCTGCGCAGCCACCCGCGTTTTCACTTCGTCGAAGGCGACATCAGCA
TTCACTCGGAGTGGATCGAGTACCACATCAAGAAATGCGACGTGGTGCTGCCGCTGGTGGCCATCGCCACGCCGATCGAA
TACACGCGCAACCCGCTGCGGGTGTTCGAACTCGACTTCGAAGAAAACCTGAAACTGGTGCGCTACTGCGTCAAATACAA
CAAGCGAGTGATCTTCCCGTCGACCTCGGAAGTCTATGGCATGTGCCAGGACAAGCACTTCGACGAAGACCGCTCGAACC
TGATCGTCGGCCCGATCAACAAGCAGCGCTGGATCTACTCGGTATCGAAGCAACTGCTGGACCGGGTGATCTGGGCCTAC
GGCGCCAAGGGCCTGAACTTCACCCTGTTCCGTCCATTCAACTGGATGGGCCCACGGCTGGATCGCCTCGATTCGGCACG
CATCGGCAGCTCCCGCGCCATTACCCAGTTGATCCTCAACCTGGTGGAAGGCACGCCGATCCGCCTGTTCGACGGCGGCG
AGCAGAAGCGCTGCTTCACCGACATCGCCGACGGCGTCGAAGCACTGGCGCGGATCATCGATAACGACAACGACGTCTGC
AACGGCCAGATCATCAACATCGGCAACCCGGACAACGAAGCGAGCATCCGCCAGTTGGGCGAAGAACTGCTGCGCCAGTT
CGAGGCTCACCCGTTGCGCAGCAACTTCCCGCCGTTCGCCGGTTTCCGCGACGTGGAAAGCAAGGCGTTCTACGGTGCCG
GTTATCAGGACGTCGAGCACCGCAAGCCGAGCATCGCCAACGCCAAGCGCCTGCTGGACTGGACGCCGACCGTCGAAATG
CGCGAGACCATCGGCAACACGCTGGACTTCTTCCTGCGCGAGGCCATGCTCGAAATCGAGAGGCCTTCCAACAAAGAGGC
ATGCTGA

Upstream 100 bases:

>100_bases
TCTTCATTGAAAAAGTCCTGCGCGGCCATCCCGCCACGCCGGCCCCCGCCATCACCGTTGACGGCCTCACTTCCAACTCC
ACGTCTGATCAGGTTCTCTC

Downstream 100 bases:

>100_bases
TGCAGGCCGGTTTGCGCATCGATGTCGACACCTTTCGCGGCACCCGTGAAGGTGTGCCGCGCTTGCTGGAAATCCTCGAT
GAAGCGCAGATCAAAGCGAC

Product: bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MSAKTVVFAYHDIGCAGIQALLDSGYDIAAVFTHAHDPKENTFYASVAQLCANNGIAVHAPEDANHPLWIERIAKLDPDY
IFSFYYRNLLSEPLLALAKKGAFNLHGSLLPRYRGRAPANWVLVNGETETGVTLHRMVKRADAGAIVAQQRVAIERSDTA
LSLHGKLRTAASDLLRDALPAMLQGRITETPQDESKATVFGRRTPADGKLVWAQPAEKLFNLVRAVTQPYPGAFCAVGEH
KLIVWSAEVVKGNEGQAPGRVISVDPLRIACGEDSLVINAGQRNDNGLYLSGPQLANELGLVDGSLLRGAESGRGPRRTR
VLILGVNGFIGNHLSERLLRDERYEVYGLDIGSDAIDRLRSHPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIE
YTRNPLRVFELDFEENLKLVRYCVKYNKRVIFPSTSEVYGMCQDKHFDEDRSNLIVGPINKQRWIYSVSKQLLDRVIWAY
GAKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFTDIADGVEALARIIDNDNDVC
NGQIINIGNPDNEASIRQLGEELLRQFEAHPLRSNFPPFAGFRDVESKAFYGAGYQDVEHRKPSIANAKRLLDWTPTVEM
RETIGNTLDFFLREAMLEIERPSNKEAC

Sequences:

>Translated_668_residues
MSAKTVVFAYHDIGCAGIQALLDSGYDIAAVFTHAHDPKENTFYASVAQLCANNGIAVHAPEDANHPLWIERIAKLDPDY
IFSFYYRNLLSEPLLALAKKGAFNLHGSLLPRYRGRAPANWVLVNGETETGVTLHRMVKRADAGAIVAQQRVAIERSDTA
LSLHGKLRTAASDLLRDALPAMLQGRITETPQDESKATVFGRRTPADGKLVWAQPAEKLFNLVRAVTQPYPGAFCAVGEH
KLIVWSAEVVKGNEGQAPGRVISVDPLRIACGEDSLVINAGQRNDNGLYLSGPQLANELGLVDGSLLRGAESGRGPRRTR
VLILGVNGFIGNHLSERLLRDERYEVYGLDIGSDAIDRLRSHPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIE
YTRNPLRVFELDFEENLKLVRYCVKYNKRVIFPSTSEVYGMCQDKHFDEDRSNLIVGPINKQRWIYSVSKQLLDRVIWAY
GAKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFTDIADGVEALARIIDNDNDVC
NGQIINIGNPDNEASIRQLGEELLRQFEAHPLRSNFPPFAGFRDVESKAFYGAGYQDVEHRKPSIANAKRLLDWTPTVEM
RETIGNTLDFFLREAMLEIERPSNKEAC
>Mature_667_residues
SAKTVVFAYHDIGCAGIQALLDSGYDIAAVFTHAHDPKENTFYASVAQLCANNGIAVHAPEDANHPLWIERIAKLDPDYI
FSFYYRNLLSEPLLALAKKGAFNLHGSLLPRYRGRAPANWVLVNGETETGVTLHRMVKRADAGAIVAQQRVAIERSDTAL
SLHGKLRTAASDLLRDALPAMLQGRITETPQDESKATVFGRRTPADGKLVWAQPAEKLFNLVRAVTQPYPGAFCAVGEHK
LIVWSAEVVKGNEGQAPGRVISVDPLRIACGEDSLVINAGQRNDNGLYLSGPQLANELGLVDGSLLRGAESGRGPRRTRV
LILGVNGFIGNHLSERLLRDERYEVYGLDIGSDAIDRLRSHPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEY
TRNPLRVFELDFEENLKLVRYCVKYNKRVIFPSTSEVYGMCQDKHFDEDRSNLIVGPINKQRWIYSVSKQLLDRVIWAYG
AKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFTDIADGVEALARIIDNDNDVCN
GQIINIGNPDNEASIRQLGEELLRQFEAHPLRSNFPPFAGFRDVESKAFYGAGYQDVEHRKPSIANAKRLLDWTPTVEMR
ETIGNTLDFFLREAMLEIERPSNKEAC

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=344, Percent_Identity=25.5813953488372, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21614513, Length=240, Percent_Identity=24.5833333333333, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI238814322, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1788589, Length=661, Percent_Identity=70.3479576399395, Blast_Score=953, Evalue=0.0,
Organism=Escherichia coli, GI1789683, Length=277, Percent_Identity=27.4368231046931, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17539532, Length=345, Percent_Identity=25.5072463768116, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 74658; Mature: 74527

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKTVVFAYHDIGCAGIQALLDSGYDIAAVFTHAHDPKENTFYASVAQLCANNGIAVHA
CCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEC
PEDANHPLWIERIAKLDPDYIFSFYYRNLLSEPLLALAKKGAFNLHGSLLPRYRGRAPAN
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
WVLVNGETETGVTLHRMVKRADAGAIVAQQRVAIERSDTALSLHGKLRTAASDLLRDALP
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHEECCCCEEEECHHHHHHHHHHHHHHHH
AMLQGRITETPQDESKATVFGRRTPADGKLVWAQPAEKLFNLVRAVTQPYPGAFCAVGEH
HHHCCCCCCCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEECCC
KLIVWSAEVVKGNEGQAPGRVISVDPLRIACGEDSLVINAGQRNDNGLYLSGPQLANELG
EEEEEEEEEEECCCCCCCCEEEEECCEEEEECCCCEEEECCCCCCCCEEEECHHHHHHHC
LVDGSLLRGAESGRGPRRTRVLILGVNGFIGNHLSERLLRDERYEVYGLDIGSDAIDRLR
CCCCHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
SHPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKLV
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHHHHHH
RYCVKYNKRVIFPSTSEVYGMCQDKHFDEDRSNLIVGPINKQRWIYSVSKQLLDRVIWAY
HHHHHHCCEEECCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
GAKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFT
CCCCCEEEEECCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHH
DIADGVEALARIIDNDNDVCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRSNFPPFA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GFRDVESKAFYGAGYQDVEHRKPSIANAKRLLDWTPTVEMRETIGNTLDFFLREAMLEIE
CCCCCCCCEEECCCCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RPSNKEAC
CCCCCCCC
>Mature Secondary Structure 
SAKTVVFAYHDIGCAGIQALLDSGYDIAAVFTHAHDPKENTFYASVAQLCANNGIAVHA
CCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEC
PEDANHPLWIERIAKLDPDYIFSFYYRNLLSEPLLALAKKGAFNLHGSLLPRYRGRAPAN
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
WVLVNGETETGVTLHRMVKRADAGAIVAQQRVAIERSDTALSLHGKLRTAASDLLRDALP
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHEECCCCEEEECHHHHHHHHHHHHHHHH
AMLQGRITETPQDESKATVFGRRTPADGKLVWAQPAEKLFNLVRAVTQPYPGAFCAVGEH
HHHCCCCCCCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEECCC
KLIVWSAEVVKGNEGQAPGRVISVDPLRIACGEDSLVINAGQRNDNGLYLSGPQLANELG
EEEEEEEEEEECCCCCCCCEEEEECCEEEEECCCCEEEECCCCCCCCEEEECHHHHHHHC
LVDGSLLRGAESGRGPRRTRVLILGVNGFIGNHLSERLLRDERYEVYGLDIGSDAIDRLR
CCCCHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
SHPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKLV
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHHHHHH
RYCVKYNKRVIFPSTSEVYGMCQDKHFDEDRSNLIVGPINKQRWIYSVSKQLLDRVIWAY
HHHHHHCCEEECCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
GAKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFT
CCCCCEEEEECCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHH
DIADGVEALARIIDNDNDVCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRSNFPPFA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GFRDVESKAFYGAGYQDVEHRKPSIANAKRLLDWTPTVEMRETIGNTLDFFLREAMLEIE
CCCCCCCCEEECCCCCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RPSNKEAC
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA