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The map label for this gene is basS [H]

Identifier: 77459058

GI number: 77459058

Start: 3266882

End: 3268195

Strand: Reverse

Name: basS [H]

Synonym: Pfl01_2833

Alternate gene names: 77459058

Gene position: 3268195-3266882 (Counterclockwise)

Preceding gene: 77459065

Following gene: 77459052

Centisome position: 50.76

GC content: 60.05

Gene sequence:

>1314_bases
ATGGATTTCAAGCAAAGCCTGACGAAACGGATCGTCATCGTATTCGCCTCGATGAGTGCGCTGGTGGCCGGCGTATTTGC
GCTGGGAATCGTAGCCACCGTGCATGTGGTGGAACACAAGTTGACGGCCACGACCTTGATGGGCGGTCTGCATCGTTTGC
TGGCAATGGATGACATCAGTCGCTGGAGCCATCGACCGGAAAAGAGCGAGCTGTTTTTCTTCGAAGGCGGACCGGGCGCC
ATGGCGCTCGTCCCGTCACTGGCGGCTCTTTCGCCGGGGTTTCAGGAGGTCATGTTCGAGGGCGATGGCTTTTTCGCCAT
GGTCGAAATGGTGGGCGGACGCAAATACGTGCTGTTGCGTGACCAGGAAAGTCTCGAACAGCGTGAGCGTCTGTTGTTCA
TTGTGGTGGCGGTCGGGTTCATCCTGAGCATTCTGCTGGCGATTGTGCTCGGCCGATTGCTGGCACGACGGGTAATGGCT
CCGGTCATCCGTCTGGCGCGCCAGGTGCGTCACCGCGACCAGTTACTGGTGCTGGCGCCGCCTCTGCATCCGGACTACGC
GGCGGACGAAGTCGGAGAACTGGCACTCTCGTTCGATCAGACGCTGGGTCGCCTGCGCGAAACGCTGAGCCGGGAAAAAC
TGTTCACCAGCGACGTGAGTCATGAACTTCGCACACCGTTGATGGTGCTCGGCGGCGCCTGCGAGTTGCTGCTCGCCAAT
CCGTCGCTCGATACCCGCTCGGCCGCGCAGGTCAACCGCATCGCACGGGCCAGTCATGAAATGCGTCAATTGGTGGATAC
CTTCCTGATGCTCGCCCGCGCCCAGGAAGATACCGGTGGCGACATTTGCGTTTCCCTTGGGGAAGTTGCACGCGTTCAGG
CGGAGATCTGGGGGCGGCTGATCCGCGAAAAAGGGCTGGAATTTTTCTGCGACATCAATCCGGCCGGCACGGCTCGTTAC
AACCAAACCTTTTTGCAGTCAGTGATGGGTAACCTGTTGCGCAATGCCTGGCATTACACCGATCAGGGTTTTGTCAGGCT
GACCGTCGGGGAATGCGGATTTGTGGTTGAAGACAGTGGCATCGGCATTCCAGAAGAACGCCGACAAGCGATGTTCCAGC
CATTCGTGCGGGGTGACGAGCGTCGAGGCGAGGGGCTTGGGCTGGGATTGTCACTGGTGCAGCGGATTTGCAATCGCGAG
CACTGGCAGGTCGACCTGACAACCCGTGAGCCCCACGGTTGTCGTTTTACCGTCCTTTTGAAGACGGACGCTCAGGACGC
CGGTGGACAGCCCCGCGCAGTGCCCGCCGCCTGA

Upstream 100 bases:

>100_bases
TGCTGTTTGAGGTGAAGCTGAATCTGTTCGGTCCATCTATTGAGTGCACACCTGATGTTGACCGCTGAGTCTGATAACCG
AGGTGGAGTCCTCCAGCCGA

Downstream 100 bases:

>100_bases
CCGATCAACGCGGCCAGACGCTTGACGTTGTTCTGCTGGGCCGCCACCAGATCGTCGATGGTCGGCCCGGACGGGGTCTG
TAGCAGCGACCGGCAGGCGA

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MDFKQSLTKRIVIVFASMSALVAGVFALGIVATVHVVEHKLTATTLMGGLHRLLAMDDISRWSHRPEKSELFFFEGGPGA
MALVPSLAALSPGFQEVMFEGDGFFAMVEMVGGRKYVLLRDQESLEQRERLLFIVVAVGFILSILLAIVLGRLLARRVMA
PVIRLARQVRHRDQLLVLAPPLHPDYAADEVGELALSFDQTLGRLRETLSREKLFTSDVSHELRTPLMVLGGACELLLAN
PSLDTRSAAQVNRIARASHEMRQLVDTFLMLARAQEDTGGDICVSLGEVARVQAEIWGRLIREKGLEFFCDINPAGTARY
NQTFLQSVMGNLLRNAWHYTDQGFVRLTVGECGFVVEDSGIGIPEERRQAMFQPFVRGDERRGEGLGLGLSLVQRICNRE
HWQVDLTTREPHGCRFTVLLKTDAQDAGGQPRAVPAA

Sequences:

>Translated_437_residues
MDFKQSLTKRIVIVFASMSALVAGVFALGIVATVHVVEHKLTATTLMGGLHRLLAMDDISRWSHRPEKSELFFFEGGPGA
MALVPSLAALSPGFQEVMFEGDGFFAMVEMVGGRKYVLLRDQESLEQRERLLFIVVAVGFILSILLAIVLGRLLARRVMA
PVIRLARQVRHRDQLLVLAPPLHPDYAADEVGELALSFDQTLGRLRETLSREKLFTSDVSHELRTPLMVLGGACELLLAN
PSLDTRSAAQVNRIARASHEMRQLVDTFLMLARAQEDTGGDICVSLGEVARVQAEIWGRLIREKGLEFFCDINPAGTARY
NQTFLQSVMGNLLRNAWHYTDQGFVRLTVGECGFVVEDSGIGIPEERRQAMFQPFVRGDERRGEGLGLGLSLVQRICNRE
HWQVDLTTREPHGCRFTVLLKTDAQDAGGQPRAVPAA
>Mature_437_residues
MDFKQSLTKRIVIVFASMSALVAGVFALGIVATVHVVEHKLTATTLMGGLHRLLAMDDISRWSHRPEKSELFFFEGGPGA
MALVPSLAALSPGFQEVMFEGDGFFAMVEMVGGRKYVLLRDQESLEQRERLLFIVVAVGFILSILLAIVLGRLLARRVMA
PVIRLARQVRHRDQLLVLAPPLHPDYAADEVGELALSFDQTLGRLRETLSREKLFTSDVSHELRTPLMVLGGACELLLAN
PSLDTRSAAQVNRIARASHEMRQLVDTFLMLARAQEDTGGDICVSLGEVARVQAEIWGRLIREKGLEFFCDINPAGTARY
NQTFLQSVMGNLLRNAWHYTDQGFVRLTVGECGFVVEDSGIGIPEERRQAMFQPFVRGDERRGEGLGLGLSLVQRICNRE
HWQVDLTTREPHGCRFTVLLKTDAQDAGGQPRAVPAA

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=319, Percent_Identity=32.6018808777429, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789808, Length=264, Percent_Identity=27.6515151515151, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786783, Length=328, Percent_Identity=26.219512195122, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=315, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=29.1139240506329, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=254, Percent_Identity=25.9842519685039, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=28.1385281385281, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787374, Length=267, Percent_Identity=27.7153558052434, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788393, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=27.3109243697479, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48459; Mature: 48459

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKQSLTKRIVIVFASMSALVAGVFALGIVATVHVVEHKLTATTLMGGLHRLLAMDDIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWSHRPEKSELFFFEGGPGAMALVPSLAALSPGFQEVMFEGDGFFAMVEMVGGRKYVLLR
HHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHCCCEEEEEE
DQESLEQRERLLFIVVAVGFILSILLAIVLGRLLARRVMAPVIRLARQVRHRDQLLVLAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
PLHPDYAADEVGELALSFDQTLGRLRETLSREKLFTSDVSHELRTPLMVLGGACELLLAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEC
PSLDTRSAAQVNRIARASHEMRQLVDTFLMLARAQEDTGGDICVSLGEVARVQAEIWGRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHHHHH
IREKGLEFFCDINPAGTARYNQTFLQSVMGNLLRNAWHYTDQGFVRLTVGECGFVVEDSG
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCC
IGIPEERRQAMFQPFVRGDERRGEGLGLGLSLVQRICNREHWQVDLTTREPHGCRFTVLL
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEE
KTDAQDAGGQPRAVPAA
EECCCCCCCCCCCCCCC
>Mature Secondary Structure
MDFKQSLTKRIVIVFASMSALVAGVFALGIVATVHVVEHKLTATTLMGGLHRLLAMDDIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWSHRPEKSELFFFEGGPGAMALVPSLAALSPGFQEVMFEGDGFFAMVEMVGGRKYVLLR
HHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHCCCEEEEEE
DQESLEQRERLLFIVVAVGFILSILLAIVLGRLLARRVMAPVIRLARQVRHRDQLLVLAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
PLHPDYAADEVGELALSFDQTLGRLRETLSREKLFTSDVSHELRTPLMVLGGACELLLAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEC
PSLDTRSAAQVNRIARASHEMRQLVDTFLMLARAQEDTGGDICVSLGEVARVQAEIWGRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHHHHH
IREKGLEFFCDINPAGTARYNQTFLQSVMGNLLRNAWHYTDQGFVRLTVGECGFVVEDSG
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCC
IGIPEERRQAMFQPFVRGDERRGEGLGLGLSLVQRICNREHWQVDLTTREPHGCRFTVLL
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEE
KTDAQDAGGQPRAVPAA
EECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]