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The map label for this gene is mngR [H]

Identifier: 77459024

GI number: 77459024

Start: 3225356

End: 3226087

Strand: Reverse

Name: mngR [H]

Synonym: Pfl01_2799

Alternate gene names: 77459024

Gene position: 3226087-3225356 (Counterclockwise)

Preceding gene: 77459025

Following gene: 77459023

Centisome position: 50.11

GC content: 59.97

Gene sequence:

>732_bases
ATGAATTCTCTTTCCAGCGATGTTCGCCTGCCGCTTTACCAACGTTTGCGTGACCACCTCGCTGAGCAGATTGCCAATAA
TCGCTGGCGCCCGGGGGAGGCCATTCCCACCGAAGCCGCGCTTTCTGCGGAATACCAGCTGTCCACCGGTACCGTGCGTA
AAGCGGTCGACGCGCTGGTCAGTGAAGGCATTCTGGAGCGTCAGCAAGGTCGAGGCACCTTCGTTCGCCGGCCTCAATTT
CAATCTTCGTTATTCCGTTTCTTCCGTTTTCAGACTGCTGCTGGTGAACGTCAGGTACCCGAGAGTCGCATCCTGTCGAT
CGAACCGATGATCGCGCCGTCGGCGGTGGCGCAGGCGCTAGGACTGCCACCTGACGCGCCGGTCATTCGCATTGTCCGAG
TACGTCTGCTCGATGTTCAGCCGGTGCTCGCCGAAGAAATCTGGCTGCCGCGCAGCCGCTTCCAGCCGCTGCTGGAGATT
GACTTGAGTCGCCAAGGGCCGCTGCTGTATCCGATCTACGAAGAGGTTTGCGGTCAGGTCGTCGCCTATGCCGAAGAAAC
ACTCACCGCTGAATCAGTGAATGAGGTGCACGCGCGATTGCTGCAAGTACCGATCAGCAGCCCCGTGGTGGTGATCGAGC
GTCTGGCGCGCGATTACGCGGGTACGCCCCTGGAGTGGCGCCGCTCCCGAGGGCATGCCGAACACTTTCGCTACAGCGTG
GATATTCGCTAA

Upstream 100 bases:

>100_bases
GTCAGCAAGAGGCCGTGCATCTTCTTGACAGTCAAGTCGTCGGAGGAAATACTCACCAAAAATTCATATAGATGACTAGA
TAACAAGGTAAATAAAGTCG

Downstream 100 bases:

>100_bases
CCCCGTGCCTGGTTAGCGGATCGTTCAGCGGCGAGTCGGTCGCCGCTGGTTTGATCGTTTTGTTTGAGATGACTGGCCCC
GAAGCGGCGCGGTTCGCGCT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNSLSSDVRLPLYQRLRDHLAEQIANNRWRPGEAIPTEAALSAEYQLSTGTVRKAVDALVSEGILERQQGRGTFVRRPQF
QSSLFRFFRFQTAAGERQVPESRILSIEPMIAPSAVAQALGLPPDAPVIRIVRVRLLDVQPVLAEEIWLPRSRFQPLLEI
DLSRQGPLLYPIYEEVCGQVVAYAEETLTAESVNEVHARLLQVPISSPVVVIERLARDYAGTPLEWRRSRGHAEHFRYSV
DIR

Sequences:

>Translated_243_residues
MNSLSSDVRLPLYQRLRDHLAEQIANNRWRPGEAIPTEAALSAEYQLSTGTVRKAVDALVSEGILERQQGRGTFVRRPQF
QSSLFRFFRFQTAAGERQVPESRILSIEPMIAPSAVAQALGLPPDAPVIRIVRVRLLDVQPVLAEEIWLPRSRFQPLLEI
DLSRQGPLLYPIYEEVCGQVVAYAEETLTAESVNEVHARLLQVPISSPVVVIERLARDYAGTPLEWRRSRGHAEHFRYSV
DIR
>Mature_243_residues
MNSLSSDVRLPLYQRLRDHLAEQIANNRWRPGEAIPTEAALSAEYQLSTGTVRKAVDALVSEGILERQQGRGTFVRRPQF
QSSLFRFFRFQTAAGERQVPESRILSIEPMIAPSAVAQALGLPPDAPVIRIVRVRLLDVQPVLAEEIWLPRSRFQPLLEI
DLSRQGPLLYPIYEEVCGQVVAYAEETLTAESVNEVHARLLQVPISSPVVVIERLARDYAGTPLEWRRSRGHAEHFRYSV
DIR

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=233, Percent_Identity=30.9012875536481, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082252, Length=214, Percent_Identity=28.9719626168224, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790118, Length=216, Percent_Identity=24.537037037037, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27530; Mature: 27530

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLSSDVRLPLYQRLRDHLAEQIANNRWRPGEAIPTEAALSAEYQLSTGTVRKAVDALV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEECHHHHHHHHHHHH
SEGILERQQGRGTFVRRPQFQSSLFRFFRFQTAAGERQVPESRILSIEPMIAPSAVAQAL
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCHHHCEEECCCCCHHHHHHHH
GLPPDAPVIRIVRVRLLDVQPVLAEEIWLPRSRFQPLLEIDLSRQGPLLYPIYEEVCGQV
CCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHCCHHEEEECCCCCCEEHHHHHHHHHHH
VAYAEETLTAESVNEVHARLLQVPISSPVVVIERLARDYAGTPLEWRRSRGHAEHFRYSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHEEEEE
DIR
CCC
>Mature Secondary Structure
MNSLSSDVRLPLYQRLRDHLAEQIANNRWRPGEAIPTEAALSAEYQLSTGTVRKAVDALV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEECHHHHHHHHHHHH
SEGILERQQGRGTFVRRPQFQSSLFRFFRFQTAAGERQVPESRILSIEPMIAPSAVAQAL
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCHHHCEEECCCCCHHHHHHHH
GLPPDAPVIRIVRVRLLDVQPVLAEEIWLPRSRFQPLLEIDLSRQGPLLYPIYEEVCGQV
CCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHCCHHEEEECCCCCCEEHHHHHHHHHHH
VAYAEETLTAESVNEVHARLLQVPISSPVVVIERLARDYAGTPLEWRRSRGHAEHFRYSV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHEEEEE
DIR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]