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The map label for this gene is mdlA [H]

Identifier: 77458999

GI number: 77458999

Start: 3199524

End: 3200693

Strand: Reverse

Name: mdlA [H]

Synonym: Pfl01_2774

Alternate gene names: 77458999

Gene position: 3200693-3199524 (Counterclockwise)

Preceding gene: 77459001

Following gene: 77458998

Centisome position: 49.71

GC content: 54.53

Gene sequence:

>1170_bases
ATGCGTATCGTAGACATCCGCGAAAAAACTGTTTCTATCGCTTCTCCCATTGCCAATGCCTACATTGATTTTTCGAAAAT
GACCTGCTCGGTCGTTGCTGTTGTCACGGATGTGATTCGCGATGGTAAACCTGTCATTGGCTACGGCTTCAACTCCAACG
GTCGCTATGGTCAAGGCGCGTTGATGCGTGATCGCTTCCTGGCGCGAATCATGGAAGCTGATCCGGATACTCTTATCGAC
CATGAGAACAACAACCTGGATCCGTTCGCCATCTGGAAGACCCTGATGACCAACGAAAAGCCAGGTGGTCACGGCGAACG
TTCAGTTGCAGTCGGCACCATTGATATGGCCGTGTGGGATGCCGTTGCCAAGATCGAAGGCAAGCCTCTCTATCGTCTGC
TGGCTGATCGGTACCGTAACGGCGTGGCCGATGAAAAAGTCTGGGTCTACGCAGCAGGTGGCTACTACTACCCAGGCAAA
GACCAGACCAAACTCAAAGCAGAAATGCAGAGCTACCTGGATCGTGGCTACGACGTTGTCAAAATGAAGATCGGTGCAGT
GCCACTGGACGAAGATATTCGTCGCATCGAAGCGGTACTCGAAGTGGTTGGGGACGGTCGTCGACTGGCGGTCGATGCCA
ACGGTCGCTTCGATCTTCAGACCGGTATTGCTTATGCGGAAGCCTTCAAGAAGTACAACCTCTTCTGGTACGAAGAAATC
GGCGACCCGCTGGACTATGCACTCCAGGCTGAGCTTGCCAATCACTACGAGCTGCCGATGGCTACCGGGGAAAACCTGTT
CTCCCATCAGGACGCTCGTAACCTTCTGCGCCACGGTGGCATGCGCCCTGATCGCGACTTTCTGCAGTTCGACTGCGCGC
TGTCTTACGGACTCGTTGAGTACATGCGCACCCTGAAAGTGATGGACGAAATGGGATGGTCTTCCCGTCGCGTGGTTCCG
CACGGCGGCCACCAGATGTCCCTCAATATCGCAGCAGGCCTGCACTTGGGTGGCAACGAGTCTTACCCCGATGTGTTCCA
GCCTTTCGGCGGCTTCGCTGACGGAATCAAGGTGGAAAATGGTTATGTCGGTCTGCCTGATATTCCAGGTGTTGGCTTCG
AAGCCAAATCCGCTTTGTACGCAGTCATGCGTGAGCTAGGCGAAGGCTGA

Upstream 100 bases:

>100_bases
AGGGCAATGCCTCCTGTGCATAGGGCGCGGCATTAATAGCATTGGGCGGGTGTCATCGCAAAGCATAACGTGGGGCCACC
AACAACAAGAGGAACCCGTC

Downstream 100 bases:

>100_bases
TTTTCCTCTATCTGTGGCCTCCTTCAGGGAGGCCGCAGAGTCAGGCGTCACCCACTGATGCCAAGCCACATGCCCATCAC
AAAAATAAAATGAGGTGCTT

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: MR [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRIVDIREKTVSIASPIANAYIDFSKMTCSVVAVVTDVIRDGKPVIGYGFNSNGRYGQGALMRDRFLARIMEADPDTLID
HENNNLDPFAIWKTLMTNEKPGGHGERSVAVGTIDMAVWDAVAKIEGKPLYRLLADRYRNGVADEKVWVYAAGGYYYPGK
DQTKLKAEMQSYLDRGYDVVKMKIGAVPLDEDIRRIEAVLEVVGDGRRLAVDANGRFDLQTGIAYAEAFKKYNLFWYEEI
GDPLDYALQAELANHYELPMATGENLFSHQDARNLLRHGGMRPDRDFLQFDCALSYGLVEYMRTLKVMDEMGWSSRRVVP
HGGHQMSLNIAAGLHLGGNESYPDVFQPFGGFADGIKVENGYVGLPDIPGVGFEAKSALYAVMRELGEG

Sequences:

>Translated_389_residues
MRIVDIREKTVSIASPIANAYIDFSKMTCSVVAVVTDVIRDGKPVIGYGFNSNGRYGQGALMRDRFLARIMEADPDTLID
HENNNLDPFAIWKTLMTNEKPGGHGERSVAVGTIDMAVWDAVAKIEGKPLYRLLADRYRNGVADEKVWVYAAGGYYYPGK
DQTKLKAEMQSYLDRGYDVVKMKIGAVPLDEDIRRIEAVLEVVGDGRRLAVDANGRFDLQTGIAYAEAFKKYNLFWYEEI
GDPLDYALQAELANHYELPMATGENLFSHQDARNLLRHGGMRPDRDFLQFDCALSYGLVEYMRTLKVMDEMGWSSRRVVP
HGGHQMSLNIAAGLHLGGNESYPDVFQPFGGFADGIKVENGYVGLPDIPGVGFEAKSALYAVMRELGEG
>Mature_389_residues
MRIVDIREKTVSIASPIANAYIDFSKMTCSVVAVVTDVIRDGKPVIGYGFNSNGRYGQGALMRDRFLARIMEADPDTLID
HENNNLDPFAIWKTLMTNEKPGGHGERSVAVGTIDMAVWDAVAKIEGKPLYRLLADRYRNGVADEKVWVYAAGGYYYPGK
DQTKLKAEMQSYLDRGYDVVKMKIGAVPLDEDIRRIEAVLEVVGDGRRLAVDANGRFDLQTGIAYAEAFKKYNLFWYEEI
GDPLDYALQAELANHYELPMATGENLFSHQDARNLLRHGGMRPDRDFLQFDCALSYGLVEYMRTLKVMDEMGWSSRRVVP
HGGHQMSLNIAAGLHLGGNESYPDVFQPFGGFADGIKVENGYVGLPDIPGVGFEAKSALYAVMRELGEG

Specific function: Unknown

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.1.2.2 [H]

Molecular weight: Translated: 43306; Mature: 43306

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVDIREKTVSIASPIANAYIDFSKMTCSVVAVVTDVIRDGKPVIGYGFNSNGRYGQGA
CCEEECHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
LMRDRFLARIMEADPDTLIDHENNNLDPFAIWKTLMTNEKPGGHGERSVAVGTIDMAVWD
HHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHH
AVAKIEGKPLYRLLADRYRNGVADEKVWVYAAGGYYYPGKDQTKLKAEMQSYLDRGYDVV
HHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHCCCEEE
KMKIGAVPLDEDIRRIEAVLEVVGDGRRLAVDANGRFDLQTGIAYAEAFKKYNLFWYEEI
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCEEHHHC
GDPLDYALQAELANHYELPMATGENLFSHQDARNLLRHGGMRPDRDFLQFDCALSYGLVE
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YMRTLKVMDEMGWSSRRVVPHGGHQMSLNIAAGLHLGGNESYPDVFQPFGGFADGIKVEN
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEECC
GYVGLPDIPGVGFEAKSALYAVMRELGEG
CEECCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIVDIREKTVSIASPIANAYIDFSKMTCSVVAVVTDVIRDGKPVIGYGFNSNGRYGQGA
CCEEECHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
LMRDRFLARIMEADPDTLIDHENNNLDPFAIWKTLMTNEKPGGHGERSVAVGTIDMAVWD
HHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHH
AVAKIEGKPLYRLLADRYRNGVADEKVWVYAAGGYYYPGKDQTKLKAEMQSYLDRGYDVV
HHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHCCCEEE
KMKIGAVPLDEDIRRIEAVLEVVGDGRRLAVDANGRFDLQTGIAYAEAFKKYNLFWYEEI
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCEEHHHC
GDPLDYALQAELANHYELPMATGENLFSHQDARNLLRHGGMRPDRDFLQFDCALSYGLVE
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YMRTLKVMDEMGWSSRRVVPHGGHQMSLNIAAGLHLGGNESYPDVFQPFGGFADGIKVEN
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEECC
GYVGLPDIPGVGFEAKSALYAVMRELGEG
CEECCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2831968; 2271624; 2215699; 1909893; 1892834; 7893689; 7893690 [H]