BacMap

Definition	Pseudomonas fluorescens Pf0-1 chromosome, complete genome.
Accession	NC_007492
Length	6,438,405

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The map label for this gene is fabG [C]

Identifier: 77458946

GI number: 77458946

Start: 3138092

End: 3138841

Strand: Reverse

Name: fabG [C]

Synonym: Pfl01_2721

Alternate gene names: 77458946

Gene position: 3138841-3138092 (Counterclockwise)

Preceding gene: 77458948

Following gene: 77458945

Centisome position: 48.75

GC content: 63.47

Gene sequence:

>750_bases
ATGCTTCTTCAAGGCAAAGTCGCGATCATCACAGGTGCTGCCTCCGCACGTGGTATCGGCCGCGCGACAGCTACGACCTT
CGCTCAACATGGCGCCTGGGTGGTGATTCTGGATCTGGACGCATCCGCTGCCCGCGATGCAGCTGCCTCTTTGGGCGAGG
GGCATCTCGGCCTGGCTGCCAACGTCGCCGACGAGTCCCAGGTGCAGCAGGCTGTCGCCACCGTCATCGAACACTTTGGC
CGGATCGACATACTGGTCAACAATGCCGGCATCACCCAACCCCTCAAGACCCTCGATATCCGCCCCGGTGATTACGATAA
GGTGCTGGACGTCAGCCTGCGCGGTACGTTGCAGATGTCCCAGGCGGTAATTCCGCTCATGCGCCAGCAAGCCAGCGGCA
GCATTGTGTGCATGTCTTCGGTTTCCGCGCAGCGCGGCGGCGGCATTTTTGGCGGGCCTCATTACAGCGCCGCCAAGGCC
GGTGTGCTGGGCCTGGCCAAGGCCATGGCGCGTGAGCTGGGGCCGGACAACGTGCGCGTCAACTCCATCGCCCCCGGCCT
GATTCACACCGACATTACTGGCGGCCTGATGCAGGACGAGCGCCGCCACGCGATCATCGACGGCATTCCGTTGGGTCGCC
TGGGCGAGGCGCAGGATGTGGCCAATGCGGCGCTGTTCCTGGCCAGCGACTTGTCCTCCTATCTGACTGGCATCACCCTG
GATGTGAACGGCGGCATGCTGATTCACTGA

Upstream 100 bases:

>100_bases
CAGTGAAGTTTGCGTTATTGCTCAGGGTCGTTGCGGGAGACAAGCTGAGTCATCGGTTCTGCACGGACCGACTCAATAAC
AACAATCAGAGGTTTCTCCC

Downstream 100 bases:

>100_bases
CACACGTGGCGGGCCTCGCGGCCCGTGCGGTTCTGGATCGATGATACGGCCGGGCAAACTTGCCCGGCGGTCAATAAAAA
CAAGAGATCAGACCATCATG

Product: Short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLLQGKVAIITGAASARGIGRATATTFAQHGAWVVILDLDASAARDAAASLGEGHLGLAANVADESQVQQAVATVIEHFG
RIDILVNNAGITQPLKTLDIRPGDYDKVLDVSLRGTLQMSQAVIPLMRQQASGSIVCMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMARELGPDNVRVNSIAPGLIHTDITGGLMQDERRHAIIDGIPLGRLGEAQDVANAALFLASDLSSYLTGITL
DVNGGMLIH

Sequences:

>Translated_249_residues
MLLQGKVAIITGAASARGIGRATATTFAQHGAWVVILDLDASAARDAAASLGEGHLGLAANVADESQVQQAVATVIEHFG
RIDILVNNAGITQPLKTLDIRPGDYDKVLDVSLRGTLQMSQAVIPLMRQQASGSIVCMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMARELGPDNVRVNSIAPGLIHTDITGGLMQDERRHAIIDGIPLGRLGEAQDVANAALFLASDLSSYLTGITL
DVNGGMLIH
>Mature_249_residues
MLLQGKVAIITGAASARGIGRATATTFAQHGAWVVILDLDASAARDAAASLGEGHLGLAANVADESQVQQAVATVIEHFG
RIDILVNNAGITQPLKTLDIRPGDYDKVLDVSLRGTLQMSQAVIPLMRQQASGSIVCMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMARELGPDNVRVNSIAPGLIHTDITGGLMQDERRHAIIDGIPLGRLGEAQDVANAALFLASDLSSYLTGITL
DVNGGMLIH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=36.5145228215768, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=38.1526104417671, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=137, Evalue=6e-33,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=35.8565737051793, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=31.6602316602317, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=35.4330708661417, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=32.6612903225806, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=34.2307692307692, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=33.0708661417323, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=35.2173913043478, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=38.1443298969072, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI31542939, Length=222, Percent_Identity=32.4324324324324, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI83715985, Length=185, Percent_Identity=37.8378378378378, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=34.5177664974619, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=34.8717948717949, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI210032110, Length=222, Percent_Identity=25.6756756756757, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI224922801, Length=183, Percent_Identity=32.7868852459016, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503817, Length=212, Percent_Identity=29.2452830188679, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI20149619, Length=215, Percent_Identity=26.5116279069767, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI310128830, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI310115468, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40254986, Length=213, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI302344755, Length=119, Percent_Identity=34.453781512605, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=29.9019607843137, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40548397, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI214010158, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI214010156, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI22758144, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=40.3225806451613, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=37.6, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=37.6470588235294, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=35.4838709677419, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=36.9918699186992, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=34.8, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=32.6771653543307, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=33.0645161290323, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.740157480315, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=29.7959183673469, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788891, Length=240, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787545, Length=268, Percent_Identity=27.9850746268657, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=41.3654618473896, Blast_Score=167, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=39.2712550607287, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=32.4, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=35.1778656126482, Blast_Score=123, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=33.7301587301587, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=33.0677290836653, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=31.5589353612167, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=31.6602316602317, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=33.969465648855, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=33.8582677165354, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=32.4528301886792, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=31.6981132075472, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=30.7692307692308, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=31.1538461538462, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=34.020618556701, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=31.1787072243346, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.9160305343511, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.7619047619048, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=32.03125, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=29.7619047619048, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=31.5573770491803, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=32.4528301886792, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=29.5880149812734, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=31.0606060606061, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=31.1538461538462, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=32.5757575757576, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=215, Percent_Identity=27.4418604651163, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.4776119402985, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=199, Percent_Identity=26.1306532663317, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=26.1306532663317, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=26.7015706806283, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=203, Percent_Identity=30.0492610837438, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=196, Percent_Identity=30.1020408163265, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=32.5490196078431, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=35.5, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323882, Length=263, Percent_Identity=27.3764258555133, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=37.7510040160643, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=36, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=37.9446640316205, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=35.3174603174603, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.1778656126482, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=34.2412451361868, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859837, Length=204, Percent_Identity=37.7450980392157, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17737361, Length=233, Percent_Identity=33.0472103004292, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=32.421875, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24649181, Length=197, Percent_Identity=26.3959390862944, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641232, Length=236, Percent_Identity=30.5084745762712, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364892, Length=195, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357673, Length=202, Percent_Identity=30.6930693069307, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358495, Length=212, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581726, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640492, Length=209, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25676; Mature: 25676

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQGKVAIITGAASARGIGRATATTFAQHGAWVVILDLDASAARDAAASLGEGHLGLAA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCEEEE
NVADESQVQQAVATVIEHFGRIDILVNNAGITQPLKTLDIRPGDYDKVLDVSLRGTLQMS
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEEEECCHHHHH
QAVIPLMRQQASGSIVCMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMARELGPDNVRV
HHHHHHHHHCCCCCEEEEECCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
NSIAPGLIHTDITGGLMQDERRHAIIDGIPLGRLGEAQDVANAALFLASDLSSYLTGITL
EEECCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
DVNGGMLIH
EECCCEEEC
>Mature Secondary Structure
MLLQGKVAIITGAASARGIGRATATTFAQHGAWVVILDLDASAARDAAASLGEGHLGLAA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCEEEE
NVADESQVQQAVATVIEHFGRIDILVNNAGITQPLKTLDIRPGDYDKVLDVSLRGTLQMS
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEEEECCHHHHH
QAVIPLMRQQASGSIVCMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMARELGPDNVRV
HHHHHHHHHCCCCCEEEEECCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
NSIAPGLIHTDITGGLMQDERRHAIIDGIPLGRLGEAQDVANAALFLASDLSSYLTGITL
EEECCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
DVNGGMLIH
EECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]