Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 77458945

GI number: 77458945

Start: 3136696

End: 3138051

Strand: Reverse

Name: ttuB [H]

Synonym: Pfl01_2720

Alternate gene names: 77458945

Gene position: 3138051-3136696 (Counterclockwise)

Preceding gene: 77458946

Following gene: 77458944

Centisome position: 48.74

GC content: 60.99

Gene sequence:

>1356_bases
ATGATACGGCCGGGCAAACTTGCCCGGCGGTCAATAAAAACAAGAGATCAGACCATCATGACTACCCTGTCGCTCGAAGC
CGTTTCGGCGGTGCGTTCCAACGCCTACCGTAAAACCGCCTGGCGCCTGATGCCGTTCCTGATGCTGTGCTACCTGTGCG
CCTACCTCGATCGCGTCAACGTCGGCTTTGCCAAACTGCAAATGATGAACGATCTGGCGCTCAGCGAAACAGTCTACGGG
CTGGGCGCGGGCATGTTCTTCATCGGCTACTTTCTCTGCGAAGTGCCCAGCAACATCATCCTGCACAAGGTCGGCGCGCG
AGTCTGGATCGCGCGCATCATGATCACCTGGGGCATTGTTTCCGCCCTCTTCGCCTTCGTCGAAACCGCCTGGCAGTTCT
ACGCCCTGCGCTTTCTGCTGGGCATTGCCGAAGCCGGCCTGGCGCCGGGGCTGCTGCTGTACCTCACCTACTGGTTTCCG
TCCTACCGGCGTGCGCGCATGACGGTGTTGTGGTTCATCGCTATCCCGCTGTCGGGCATGGTCGGCGGCCCGCTCTCCGG
CTGGATCATGAACCACTTCGCCGGTATGCACGGCTGGGCCGGCTGGCAATGGATGTTTGTGCTGGAGGCTGTGCCTACGG
TGGTTGTCGGACTGTTGGTGCTCAGCTATCTCAAGGATGGCGTGCATCAGGCCAGTTGGCTCAACGACGACGAAAAAGCC
CTGATCACCCGTGAGCTGGCGGAGGATGACCAGCAGAAAGTGACGCATGCGTCCGTGGGCGAATTCATTCGTGACCGTCG
CCTCTGGCTGCTCGCGGGGATCTATTTCTGTGTGGTGATGGGACAGTACGCAATTACCTTCTGGCTGCCGACCCTTGTGC
GTAATGCCGGTGTCTCCGATCCGATGAAGATCGGCTTGCTGACCAGCCTGCCTTATCTCTGTGCCATCGCCGCCATGTTG
CTGGTCGGACGCAGTGGCGACAAACATCGCGAACGCCGCTGGCACCTGATCGTGCCGATGATCGCCGGGGCCATCGGCCT
GACCCTCGCGGCGCTGATGGGAGGCAATGTGATGCTGTCCATTCTCAGTCTGTGCCTGGCGGCTTCCGGCATCCTGTCCG
CGACCTCGCTGTTCTGGATGCTCCCCACCACGCTGCTTGGTGGTGTCTCCGCCGCGGCCGGCATCGCCGCCGTCAACAGT
TTCGCCAACCTTGCCGGCTTCTGCTCGCCCTACCTGATTGGCTGGATAACCACACTCACAGGCTCCAGCGCTATCGGCAT
GTACCTGATCACCGGCGTATTGCTGATCGGCGCCTCGCTGGTCCTGCGCATTCCCGCTGCCTTGGTCAATCGTTGA

Upstream 100 bases:

>100_bases
TTGTCCTCCTATCTGACTGGCATCACCCTGGATGTGAACGGCGGCATGCTGATTCACTGACACACGTGGCGGGCCTCGCG
GCCCGTGCGGTTCTGGATCG

Downstream 100 bases:

>100_bases
TTCACAGGAGAATTCACCATGACTGCCAACCTTTCATTCACAACACCCCAGACGCTGGCCGAGCGCGCCCACAACATCCG
CCGCCATGCCTTGCGCATGG

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MIRPGKLARRSIKTRDQTIMTTLSLEAVSAVRSNAYRKTAWRLMPFLMLCYLCAYLDRVNVGFAKLQMMNDLALSETVYG
LGAGMFFIGYFLCEVPSNIILHKVGARVWIARIMITWGIVSALFAFVETAWQFYALRFLLGIAEAGLAPGLLLYLTYWFP
SYRRARMTVLWFIAIPLSGMVGGPLSGWIMNHFAGMHGWAGWQWMFVLEAVPTVVVGLLVLSYLKDGVHQASWLNDDEKA
LITRELAEDDQQKVTHASVGEFIRDRRLWLLAGIYFCVVMGQYAITFWLPTLVRNAGVSDPMKIGLLTSLPYLCAIAAML
LVGRSGDKHRERRWHLIVPMIAGAIGLTLAALMGGNVMLSILSLCLAASGILSATSLFWMLPTTLLGGVSAAAGIAAVNS
FANLAGFCSPYLIGWITTLTGSSAIGMYLITGVLLIGASLVLRIPAALVNR

Sequences:

>Translated_451_residues
MIRPGKLARRSIKTRDQTIMTTLSLEAVSAVRSNAYRKTAWRLMPFLMLCYLCAYLDRVNVGFAKLQMMNDLALSETVYG
LGAGMFFIGYFLCEVPSNIILHKVGARVWIARIMITWGIVSALFAFVETAWQFYALRFLLGIAEAGLAPGLLLYLTYWFP
SYRRARMTVLWFIAIPLSGMVGGPLSGWIMNHFAGMHGWAGWQWMFVLEAVPTVVVGLLVLSYLKDGVHQASWLNDDEKA
LITRELAEDDQQKVTHASVGEFIRDRRLWLLAGIYFCVVMGQYAITFWLPTLVRNAGVSDPMKIGLLTSLPYLCAIAAML
LVGRSGDKHRERRWHLIVPMIAGAIGLTLAALMGGNVMLSILSLCLAASGILSATSLFWMLPTTLLGGVSAAAGIAAVNS
FANLAGFCSPYLIGWITTLTGSSAIGMYLITGVLLIGASLVLRIPAALVNR
>Mature_451_residues
MIRPGKLARRSIKTRDQTIMTTLSLEAVSAVRSNAYRKTAWRLMPFLMLCYLCAYLDRVNVGFAKLQMMNDLALSETVYG
LGAGMFFIGYFLCEVPSNIILHKVGARVWIARIMITWGIVSALFAFVETAWQFYALRFLLGIAEAGLAPGLLLYLTYWFP
SYRRARMTVLWFIAIPLSGMVGGPLSGWIMNHFAGMHGWAGWQWMFVLEAVPTVVVGLLVLSYLKDGVHQASWLNDDEKA
LITRELAEDDQQKVTHASVGEFIRDRRLWLLAGIYFCVVMGQYAITFWLPTLVRNAGVSDPMKIGLLTSLPYLCAIAAML
LVGRSGDKHRERRWHLIVPMIAGAIGLTLAALMGGNVMLSILSLCLAASGILSATSLFWMLPTTLLGGVSAAAGIAAVNS
FANLAGFCSPYLIGWITTLTGSSAIGMYLITGVLLIGASLVLRIPAALVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=433, Percent_Identity=36.7205542725173, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1789152, Length=429, Percent_Identity=22.8438228438228, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367379, Length=421, Percent_Identity=23.7529691211401, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=441, Percent_Identity=23.3560090702948, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789515, Length=396, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322025, Length=247, Percent_Identity=25.9109311740891, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=367, Percent_Identity=24.2506811989101, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=292, Percent_Identity=27.0547945205479, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=289, Percent_Identity=22.8373702422145, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=364, Percent_Identity=21.1538461538462, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=326, Percent_Identity=24.8466257668712, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=148, Percent_Identity=28.3783783783784, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49505; Mature: 49505

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]