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The map label for this gene is dxs [C]

Identifier: 77458943

GI number: 77458943

Start: 3134810

End: 3135832

Strand: Reverse

Name: dxs [C]

Synonym: Pfl01_2718

Alternate gene names: 77458943

Gene position: 3135832-3134810 (Counterclockwise)

Preceding gene: 77458944

Following gene: 77458941

Centisome position: 48.71

GC content: 61.29

Gene sequence:

>1023_bases
ATGAGCAACGCCGCCAACACACCGACCTCGACTGGTGAACCGATCAAGAAGCGCCTGACCACCTCGGCGATGATTGCCTC
GATTGCCTCTGAAGGCCAAGCCACCCGCTCAGCACCTTTTGGCCATGCATTGGCTGCACTGGCGGATCAGCGTCCGGACA
TCGTCGGCCTCTCCGCTGACCTGTCCAAGTACACCGACCTGCACATTTTCGCCAAGGCCCACCCGGATCGTTTCTATCAG
ATGGGCATGGCCGAACAGTTGCTCATGAGTGCGGCCGCAGGCATGGCCCGCGAAGGATTCGTGCCGTTCGCGACCACGTA
TGCGGTGTTCGCCTCGCGTCGCGCCTATGACTTCATCTGCATGGCCATTGCCGAGGAAAACCTCAACGTCAAAATCGTTT
GCGGATTGCCCGGCCTCACCACCGGTTACGGCCCCAGCCACCAGGCCACCGATGACCTGGCGATCTTCCGGGCGATGCCC
AACCTGATGATCGTCGACCCTTGTGATGCCTTGGAAATCGAACAGGCCGTGCCCGCCATTGCCGCGCATCAGGGGCCGGT
CTACATGCGGCTGCTGCGCGGCAACGTGCCGCTGGTGCTGGATGAGTACGGGTATCAATTCGAGATCGGCAAGGCCAAGA
CCCTGCGCACCGGCAACGATGTCCTGATCATCTCGACCGGTTTGATGACCATGCGCGCATTGGAGGCCGCCAAGGCGCTG
CAGACCGATGGCGTCGATGTCGCCGTGCTGCATGTGCCGACGATCAAACCGCTGGATGAACAGACCATTCTCGCCGAGGC
CCGCAAGTCTGGCCGGCTGGTGGTTACCGCAGAAAACAGCTCGATTATTGGCGGGCTCGGTGAAGCGGTTGCCGGGGTAC
TGCTGCGCAACGGAGTGACGCCGACGTTCAGGCAGATTGCATTGCCCGACGCCTTCCTCGACGCCGGTGCATTGCCGACA
CTGCATGATCGCTATGGCATTTCCACCGACGCCGTCTGCGCGCAAATCAAATCCTGGCTTTGA

Upstream 100 bases:

>100_bases
GTGTGCCCTTCCTCGAAAACCGCGAAAAGACCCATTTCATCCGTGTGGACGAACACGAATGGGATCTGGCACTGACCACG
CTTGAAGAAGGAAAAAACCA

Downstream 100 bases:

>100_bases
CTGCTGATCGGGGCGCTTACGGATGAGCGGCCCGATCAGATGGATTCTCCTGGCCGATCCGCCTGGCATCCCTTCGAACT
GCCTGCGGCGGAACGCCAAA

Product: transketolase subunit B

Products: D-ribose 5-phosphate; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSNAANTPTSTGEPIKKRLTTSAMIASIASEGQATRSAPFGHALAALADQRPDIVGLSADLSKYTDLHIFAKAHPDRFYQ
MGMAEQLLMSAAAGMAREGFVPFATTYAVFASRRAYDFICMAIAEENLNVKIVCGLPGLTTGYGPSHQATDDLAIFRAMP
NLMIVDPCDALEIEQAVPAIAAHQGPVYMRLLRGNVPLVLDEYGYQFEIGKAKTLRTGNDVLIISTGLMTMRALEAAKAL
QTDGVDVAVLHVPTIKPLDEQTILAEARKSGRLVVTAENSSIIGGLGEAVAGVLLRNGVTPTFRQIALPDAFLDAGALPT
LHDRYGISTDAVCAQIKSWL

Sequences:

>Translated_340_residues
MSNAANTPTSTGEPIKKRLTTSAMIASIASEGQATRSAPFGHALAALADQRPDIVGLSADLSKYTDLHIFAKAHPDRFYQ
MGMAEQLLMSAAAGMAREGFVPFATTYAVFASRRAYDFICMAIAEENLNVKIVCGLPGLTTGYGPSHQATDDLAIFRAMP
NLMIVDPCDALEIEQAVPAIAAHQGPVYMRLLRGNVPLVLDEYGYQFEIGKAKTLRTGNDVLIISTGLMTMRALEAAKAL
QTDGVDVAVLHVPTIKPLDEQTILAEARKSGRLVVTAENSSIIGGLGEAVAGVLLRNGVTPTFRQIALPDAFLDAGALPT
LHDRYGISTDAVCAQIKSWL
>Mature_339_residues
SNAANTPTSTGEPIKKRLTTSAMIASIASEGQATRSAPFGHALAALADQRPDIVGLSADLSKYTDLHIFAKAHPDRFYQM
GMAEQLLMSAAAGMAREGFVPFATTYAVFASRRAYDFICMAIAEENLNVKIVCGLPGLTTGYGPSHQATDDLAIFRAMPN
LMIVDPCDALEIEQAVPAIAAHQGPVYMRLLRGNVPLVLDEYGYQFEIGKAKTLRTGNDVLIISTGLMTMRALEAAKALQ
TDGVDVAVLHVPTIKPLDEQTILAEARKSGRLVVTAENSSIIGGLGEAVAGVLLRNGVTPTFRQIALPDAFLDAGALPTL
HDRYGISTDAVCAQIKSWL

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=311, Percent_Identity=35.3697749196142, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4507521, Length=311, Percent_Identity=35.3697749196142, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI225637459, Length=313, Percent_Identity=34.8242811501597, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI225637461, Length=313, Percent_Identity=34.8242811501597, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI225637463, Length=313, Percent_Identity=34.8242811501597, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI133778974, Length=303, Percent_Identity=34.983498349835, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786622, Length=313, Percent_Identity=29.3929712460064, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788808, Length=280, Percent_Identity=28.9285714285714, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539652, Length=311, Percent_Identity=36.6559485530547, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24645119, Length=314, Percent_Identity=33.4394904458599, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45551847, Length=314, Percent_Identity=33.4394904458599, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45550715, Length=314, Percent_Identity=33.4394904458599, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666278, Length=296, Percent_Identity=31.0810810810811, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: 2.2.1.1

Molecular weight: Translated: 36216; Mature: 36085

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAANTPTSTGEPIKKRLTTSAMIASIASEGQATRSAPFGHALAALADQRPDIVGLSAD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCC
LSKYTDLHIFAKAHPDRFYQMGMAEQLLMSAAAGMAREGFVPFATTYAVFASRRAYDFIC
HHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCHHHEEE
MAIAEENLNVKIVCGLPGLTTGYGPSHQATDDLAIFRAMPNLMIVDPCDALEIEQAVPAI
EEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHCCHH
AAHQGPVYMRLLRGNVPLVLDEYGYQFEIGKAKTLRTGNDVLIISTGLMTMRALEAAKAL
HCCCCCEEEEEECCCCCEEECCCCCEEEECCCEEEECCCCEEEEECCHHHHHHHHHHHHH
QTDGVDVAVLHVPTIKPLDEQTILAEARKSGRLVVTAENSSIIGGLGEAVAGVLLRNGVT
HCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCEECHHHHHHHHHHHHCCCC
PTFRQIALPDAFLDAGALPTLHDRYGISTDAVCAQIKSWL
HHHHHHCCCHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SNAANTPTSTGEPIKKRLTTSAMIASIASEGQATRSAPFGHALAALADQRPDIVGLSAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCC
LSKYTDLHIFAKAHPDRFYQMGMAEQLLMSAAAGMAREGFVPFATTYAVFASRRAYDFIC
HHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCHHHEEE
MAIAEENLNVKIVCGLPGLTTGYGPSHQATDDLAIFRAMPNLMIVDPCDALEIEQAVPAI
EEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHCCHH
AAHQGPVYMRLLRGNVPLVLDEYGYQFEIGKAKTLRTGNDVLIISTGLMTMRALEAAKAL
HCCCCCEEEEEECCCCCEEECCCCCEEEECCCEEEECCCCEEEEECCHHHHHHHHHHHHH
QTDGVDVAVLHVPTIKPLDEQTILAEARKSGRLVVTAENSSIIGGLGEAVAGVLLRNGVT
HCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCEECHHHHHHHHHHHHCCCC
PTFRQIALPDAFLDAGALPTLHDRYGISTDAVCAQIKSWL
HHHHHHCCCHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sedoheptulose 7-phosphate; D-glyceraldehyde 3-phosphate

Specific reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]