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The map label for this gene is iorA [H]

Identifier: 77458698

GI number: 77458698

Start: 2828122

End: 2828577

Strand: Reverse

Name: iorA [H]

Synonym: Pfl01_2473

Alternate gene names: 77458698

Gene position: 2828577-2828122 (Counterclockwise)

Preceding gene: 77458699

Following gene: 77458697

Centisome position: 43.93

GC content: 63.16

Gene sequence:

>456_bases
ATGGAACTACGAATCAACCAGAAGACCTACCAGGTCGATGCCGACGCCGATACGCCCTTGCTGTGGGTGATCCGCGATGA
TCTGGGCATGACCGGCACCAAGTACGGCTGCGGACTGGCGCAATGCGGCGCCTGCTCTGTGCTGGTGGACGGCAATGTGG
TGCGTTCCTGCGTCACGCCGGTGGCGGGTGTGGTTGGCCGCGAGGTCACCACGATTGAGGCCATCGAAGCCGATGAAGTG
GGCAAACGGGTGGTCTCGACCTGGGTCGATCTGCAAGTCGCCCAGTGCGGTTACTGCCAGTCCGGGCAGGTGATGGCTGC
CACCGCGCTGCTCAAGCAGAACCCCAAACCGAGTGATGCGCAGATCGAGGCGGCGATGGTCAACCTGTGCCGCTGCGGTA
CCTACAACGCCATTCATGCCGCCGTGCATGAACTTGCCGGCAAGGGGGACGCGTGA

Upstream 100 bases:

>100_bases
GCTCGGCACAGTCGCGAATTGAACGAAAACCGGTGATGCGCCCCGCCGCGTGTCACCGTTCATAACAATGCACGTCAACC
GATGATCAAGCGGGTGAACC

Downstream 100 bases:

>100_bases
TGAACGTTCGTATCGACCCTTCACAACACGCTTCAGTACTGGATCTGCAGGAACCGATCAATGTGTCGCGCAGACGTTTT
CTGACCGGTACCGCCGTCGG

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MELRINQKTYQVDADADTPLLWVIRDDLGMTGTKYGCGLAQCGACSVLVDGNVVRSCVTPVAGVVGREVTTIEAIEADEV
GKRVVSTWVDLQVAQCGYCQSGQVMAATALLKQNPKPSDAQIEAAMVNLCRCGTYNAIHAAVHELAGKGDA

Sequences:

>Translated_151_residues
MELRINQKTYQVDADADTPLLWVIRDDLGMTGTKYGCGLAQCGACSVLVDGNVVRSCVTPVAGVVGREVTTIEAIEADEV
GKRVVSTWVDLQVAQCGYCQSGQVMAATALLKQNPKPSDAQIEAAMVNLCRCGTYNAIHAAVHELAGKGDA
>Mature_151_residues
MELRINQKTYQVDADADTPLLWVIRDDLGMTGTKYGCGLAQCGACSVLVDGNVVRSCVTPVAGVVGREVTTIEAIEADEV
GKRVVSTWVDLQVAQCGYCQSGQVMAATALLKQNPKPSDAQIEAAMVNLCRCGTYNAIHAAVHELAGKGDA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=148, Percent_Identity=34.4594594594595, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=35.3658536585366, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=36.1702127659575, Blast_Score=83, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=36.6013071895425, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=144, Percent_Identity=31.9444444444444, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32566215, Length=147, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17737937, Length=144, Percent_Identity=36.1111111111111, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=31.875, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15943; Mature: 15943

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRINQKTYQVDADADTPLLWVIRDDLGMTGTKYGCGLAQCGACSVLVDGNVVRSCVTP
CCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
VAGVVGREVTTIEAIEADEVGKRVVSTWVDLQVAQCGYCQSGQVMAATALLKQNPKPSDA
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCH
QIEAAMVNLCRCGTYNAIHAAVHELAGKGDA
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELRINQKTYQVDADADTPLLWVIRDDLGMTGTKYGCGLAQCGACSVLVDGNVVRSCVTP
CCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
VAGVVGREVTTIEAIEADEVGKRVVSTWVDLQVAQCGYCQSGQVMAATALLKQNPKPSDA
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCH
QIEAAMVNLCRCGTYNAIHAAVHELAGKGDA
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]