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The map label for this gene is iorB [H]

Identifier: 77458697

GI number: 77458697

Start: 2825873

End: 2828122

Strand: Reverse

Name: iorB [H]

Synonym: Pfl01_2472

Alternate gene names: 77458697

Gene position: 2828122-2825873 (Counterclockwise)

Preceding gene: 77458698

Following gene: 77458696

Centisome position: 43.93

GC content: 63.47

Gene sequence:

>2250_bases
ATGAACGTTCGTATCGACCCTTCACAACACGCTTCAGTACTGGATCTGCAGGAACCGATCAATGTGTCGCGCAGACGTTT
TCTGACCGGTACCGCCGTCGGCGCACTGGTGCTCGGCTTCGGTCTGCCGCTCGGTGCGACACGGGTACAAGCGGCAGCGG
CAGCGACTGCCGAGCGTGGCACCCAAGTCCCGGCGTTTCTCGAAATCCGCCCGGACAACCGCGTGCGTCTGCTCTGCCCG
TTCATGGAAGGCGGGCAAGGCACGTTCACCGCCATGGCGCAGATCGTCGGTGAAGAACTGGATGCGGACCCGGCGACCTT
CCTGGTCGAAGCAGCGCCGCCCGGAGAAGCCTACGTGGTGATGGAAAACGGCCTGCGCATCACCGGCGGCAGCATGTCGG
TGCGCATGAGTTACCCGGTCATGCGTCGCCTCGGCGCCCTCGCCCGCGCCATGCTGTTGCAGGCCGGCGCGCAGCAACTG
GGCGTGCCGGTGAGCGAGTTGAGCACCGAGCCGGGCAAGGTCGTGCATGCCAAGTCCGGGCGTTCGTTGGCCTACGGTGA
ACTGGCCGAGCGCGCGATGGATCTGCCGGTTCCCGATCCGGCCTCGGTGAAGCTGCGTGATCCGAGCCAGTTCCGCTGGA
TCGGCAAACCGGTGAAGCGTCTCGACGCTTACGACAAATCCACCGGCAAGGCGCTGTACAGCATCGATCTGAAAGTCGAC
GACATGCTGCATGCCGCCGTTCAACATGCCCCGCGCCTGGGGATGACCGTGGGCAACCTGCGCAACGAAGAGCAGGTCAA
GGCGATGAAAGGCGTGCATTCCGTGCATCGTCTGCCGGGCGCCGTGGCGGTGGTCGCCGAGCGCTGGTGGCACGCCAAAC
GTGCCGTCGAGGCGATTCAGGTCGACTGGCAAGAGCCGACGGCCGACAGCAAAGTACGGCCGATGCCCGCCGACTTTTCC
AGCGATGCCTGGTTCAAGCGCCTCGCTGAAGATAAAAGCCCCGCCAAAGATGATGAACACGAAGGCGATGTGGCTTCGAT
TCTCAAGGAAACCAAGACCCGGATTGACGCCACTTACCACAACCAATACCTGAACCACGGACAGCTGGAGCCGCCTTCAG
CACTGGCCCGATTCAATCCGGATGGTTCGCTTGAGGTCTGGCTGCCGAATCAGGCGCCGGACATGTTCCGCGCCGATATC
GCCAAACGCACCGGGCTCGATCCGTCACGCATCACCTTGCATTCGCCGCTGTTGGGCGGGTTCTTCGGTCGGCATTTCCT
CTACGACTCGGCCAGTCCCTACCCTCAGGCCATCGCGCTGGCCAAAGCGGTTGGGCGCCCGGTCAAACTGATCTGGAGTC
GCGAAGAAGAGTTCCTGCGTGACGTGCTTCGCCCGGTTGCCGCAGTGAATTTCCGTGCCGCACTGGACAGCGACGGCTGG
CCGCTGGCAATCGAAGCGATCAGTGCCACCGAAGGCCCGACCGAAGCCCTCGCCGGCAAACAGGGTGAAAAGCTCGACCC
GACGGCGCTCGAAGGGTTGTCAGGCAAGTCCTATGCGATCCCCAACAAGCGCATCGCGCAGATTTACGTCAAAGGCCCGG
CGATGCTCGGCTACTGGCGTTCGGTGGGCAATTCCCTCAACGACTTCTTCTATGAATCGTTCCTCGATGAACTGGCCGAC
AAAGGGGGCAAAGACCCATTCGAGCTGCGCCTGCATTTGCTGCGTGACAACAAACGCCTGACCACGCTGCTACAAGCGGT
GGGTGAACTGTCCGGAGGCTGGAAGCGCGGGCCGTTTACCGCCGAGGATGGCAGCCGACGTGCGCGCGGCGTGGCCATGG
CTTCGCCGTTCGGTACCGAGACGGCGGTGATCGCTGAGGTGTCCATCGAGAACGGCCAGGTCAAGGTGCACGACATCTGG
CAGGCGATTGATCCGGGCAGCATCGTCAATCCGGCGATTGTCGAGGCTCAGGTGAACGGCGCCGTGGCGTTGGGACTGTC
GCAAACGCTGGTCGAGGAAGCCGTGTGGGTGGATGGCAAACCCCGGGCGCGCAACTACGACTTGTACCCGATCCTGCCGC
CTGCGCGGATGGCACGGGTGCATGTGCGGGTGGTCGAGAGCGGGGAAAAAATGGGTGGCATTGGTGAACCGCCGTTGCCT
GCGGTCGCGCCCGCTGTCGCTAACGCGGTGGCGACGCTGACCGGTCAGCGGGTACGCAGCCTGCCCTTGAGCCGACACAC
TTTCACCTGA

Upstream 100 bases:

>100_bases
ATGCGCAGATCGAGGCGGCGATGGTCAACCTGTGCCGCTGCGGTACCTACAACGCCATTCATGCCGCCGTGCATGAACTT
GCCGGCAAGGGGGACGCGTG

Downstream 100 bases:

>100_bases
TCAGCGCCGGAGCGTTCATGAATAACAGCCGATTCGCAAGAACCGCTGGCTGGCTGGCCGTGCCGTGTCTGGTCGCGGCA
GGCCTGCTGGCCTGGTATGT

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MNVRIDPSQHASVLDLQEPINVSRRRFLTGTAVGALVLGFGLPLGATRVQAAAAATAERGTQVPAFLEIRPDNRVRLLCP
FMEGGQGTFTAMAQIVGEELDADPATFLVEAAPPGEAYVVMENGLRITGGSMSVRMSYPVMRRLGALARAMLLQAGAQQL
GVPVSELSTEPGKVVHAKSGRSLAYGELAERAMDLPVPDPASVKLRDPSQFRWIGKPVKRLDAYDKSTGKALYSIDLKVD
DMLHAAVQHAPRLGMTVGNLRNEEQVKAMKGVHSVHRLPGAVAVVAERWWHAKRAVEAIQVDWQEPTADSKVRPMPADFS
SDAWFKRLAEDKSPAKDDEHEGDVASILKETKTRIDATYHNQYLNHGQLEPPSALARFNPDGSLEVWLPNQAPDMFRADI
AKRTGLDPSRITLHSPLLGGFFGRHFLYDSASPYPQAIALAKAVGRPVKLIWSREEEFLRDVLRPVAAVNFRAALDSDGW
PLAIEAISATEGPTEALAGKQGEKLDPTALEGLSGKSYAIPNKRIAQIYVKGPAMLGYWRSVGNSLNDFFYESFLDELAD
KGGKDPFELRLHLLRDNKRLTTLLQAVGELSGGWKRGPFTAEDGSRRARGVAMASPFGTETAVIAEVSIENGQVKVHDIW
QAIDPGSIVNPAIVEAQVNGAVALGLSQTLVEEAVWVDGKPRARNYDLYPILPPARMARVHVRVVESGEKMGGIGEPPLP
AVAPAVANAVATLTGQRVRSLPLSRHTFT

Sequences:

>Translated_749_residues
MNVRIDPSQHASVLDLQEPINVSRRRFLTGTAVGALVLGFGLPLGATRVQAAAAATAERGTQVPAFLEIRPDNRVRLLCP
FMEGGQGTFTAMAQIVGEELDADPATFLVEAAPPGEAYVVMENGLRITGGSMSVRMSYPVMRRLGALARAMLLQAGAQQL
GVPVSELSTEPGKVVHAKSGRSLAYGELAERAMDLPVPDPASVKLRDPSQFRWIGKPVKRLDAYDKSTGKALYSIDLKVD
DMLHAAVQHAPRLGMTVGNLRNEEQVKAMKGVHSVHRLPGAVAVVAERWWHAKRAVEAIQVDWQEPTADSKVRPMPADFS
SDAWFKRLAEDKSPAKDDEHEGDVASILKETKTRIDATYHNQYLNHGQLEPPSALARFNPDGSLEVWLPNQAPDMFRADI
AKRTGLDPSRITLHSPLLGGFFGRHFLYDSASPYPQAIALAKAVGRPVKLIWSREEEFLRDVLRPVAAVNFRAALDSDGW
PLAIEAISATEGPTEALAGKQGEKLDPTALEGLSGKSYAIPNKRIAQIYVKGPAMLGYWRSVGNSLNDFFYESFLDELAD
KGGKDPFELRLHLLRDNKRLTTLLQAVGELSGGWKRGPFTAEDGSRRARGVAMASPFGTETAVIAEVSIENGQVKVHDIW
QAIDPGSIVNPAIVEAQVNGAVALGLSQTLVEEAVWVDGKPRARNYDLYPILPPARMARVHVRVVESGEKMGGIGEPPLP
AVAPAVANAVATLTGQRVRSLPLSRHTFT
>Mature_749_residues
MNVRIDPSQHASVLDLQEPINVSRRRFLTGTAVGALVLGFGLPLGATRVQAAAAATAERGTQVPAFLEIRPDNRVRLLCP
FMEGGQGTFTAMAQIVGEELDADPATFLVEAAPPGEAYVVMENGLRITGGSMSVRMSYPVMRRLGALARAMLLQAGAQQL
GVPVSELSTEPGKVVHAKSGRSLAYGELAERAMDLPVPDPASVKLRDPSQFRWIGKPVKRLDAYDKSTGKALYSIDLKVD
DMLHAAVQHAPRLGMTVGNLRNEEQVKAMKGVHSVHRLPGAVAVVAERWWHAKRAVEAIQVDWQEPTADSKVRPMPADFS
SDAWFKRLAEDKSPAKDDEHEGDVASILKETKTRIDATYHNQYLNHGQLEPPSALARFNPDGSLEVWLPNQAPDMFRADI
AKRTGLDPSRITLHSPLLGGFFGRHFLYDSASPYPQAIALAKAVGRPVKLIWSREEEFLRDVLRPVAAVNFRAALDSDGW
PLAIEAISATEGPTEALAGKQGEKLDPTALEGLSGKSYAIPNKRIAQIYVKGPAMLGYWRSVGNSLNDFFYESFLDELAD
KGGKDPFELRLHLLRDNKRLTTLLQAVGELSGGWKRGPFTAEDGSRRARGVAMASPFGTETAVIAEVSIENGQVKVHDIW
QAIDPGSIVNPAIVEAQVNGAVALGLSQTLVEEAVWVDGKPRARNYDLYPILPPARMARVHVRVVESGEKMGGIGEPPLP
AVAPAVANAVATLTGQRVRSLPLSRHTFT

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=406, Percent_Identity=23.1527093596059, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 81287; Mature: 81287

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRIDPSQHASVLDLQEPINVSRRRFLTGTAVGALVLGFGLPLGATRVQAAAAATAERG
CCEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
TQVPAFLEIRPDNRVRLLCPFMEGGQGTFTAMAQIVGEELDADPATFLVEAAPPGEAYVV
CCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
MENGLRITGGSMSVRMSYPVMRRLGALARAMLLQAGAQQLGVPVSELSTEPGKVVHAKSG
EECCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCEEEECCC
RSLAYGELAERAMDLPVPDPASVKLRDPSQFRWIGKPVKRLDAYDKSTGKALYSIDLKVD
CCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
DMLHAAVQHAPRLGMTVGNLRNEEQVKAMKGVHSVHRLPGAVAVVAERWWHAKRAVEAIQ
HHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHE
VDWQEPTADSKVRPMPADFSSDAWFKRLAEDKSPAKDDEHEGDVASILKETKTRIDATYH
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NQYLNHGQLEPPSALARFNPDGSLEVWLPNQAPDMFRADIAKRTGLDPSRITLHSPLLGG
HHHHCCCCCCCCHHHHEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCHHHH
FFGRHFLYDSASPYPQAIALAKAVGRPVKLIWSREEEFLRDVLRPVAAVNFRAALDSDGW
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCC
PLAIEAISATEGPTEALAGKQGEKLDPTALEGLSGKSYAIPNKRIAQIYVKGPAMLGYWR
EEEEEEEECCCCCHHHHCCCCCCCCCCHHHCCCCCCCEECCCCCEEEEEEECCHHHHHHH
SVGNSLNDFFYESFLDELADKGGKDPFELRLHLLRDNKRLTTLLQAVGELSGGWKRGPFT
HHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCC
AEDGSRRARGVAMASPFGTETAVIAEVSIENGQVKVHDIWQAIDPGSIVNPAIVEAQVNG
CCCCCCHHCCEEEECCCCCCEEEEEEEEECCCEEEEEEHHHHCCCCCCCCCCEEEEECCC
AVALGLSQTLVEEAVWVDGKPRARNYDLYPILPPARMARVHVRVVESGEKMGGIGEPPLP
EEEECHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHEEEEEEECCCCCCCCCCCCCC
AVAPAVANAVATLTGQRVRSLPLSRHTFT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNVRIDPSQHASVLDLQEPINVSRRRFLTGTAVGALVLGFGLPLGATRVQAAAAATAERG
CCEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
TQVPAFLEIRPDNRVRLLCPFMEGGQGTFTAMAQIVGEELDADPATFLVEAAPPGEAYVV
CCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEE
MENGLRITGGSMSVRMSYPVMRRLGALARAMLLQAGAQQLGVPVSELSTEPGKVVHAKSG
EECCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCEEEECCC
RSLAYGELAERAMDLPVPDPASVKLRDPSQFRWIGKPVKRLDAYDKSTGKALYSIDLKVD
CCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
DMLHAAVQHAPRLGMTVGNLRNEEQVKAMKGVHSVHRLPGAVAVVAERWWHAKRAVEAIQ
HHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHE
VDWQEPTADSKVRPMPADFSSDAWFKRLAEDKSPAKDDEHEGDVASILKETKTRIDATYH
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NQYLNHGQLEPPSALARFNPDGSLEVWLPNQAPDMFRADIAKRTGLDPSRITLHSPLLGG
HHHHCCCCCCCCHHHHEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCHHHH
FFGRHFLYDSASPYPQAIALAKAVGRPVKLIWSREEEFLRDVLRPVAAVNFRAALDSDGW
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCC
PLAIEAISATEGPTEALAGKQGEKLDPTALEGLSGKSYAIPNKRIAQIYVKGPAMLGYWR
EEEEEEEECCCCCHHHHCCCCCCCCCCHHHCCCCCCCEECCCCCEEEEEEECCHHHHHHH
SVGNSLNDFFYESFLDELADKGGKDPFELRLHLLRDNKRLTTLLQAVGELSGGWKRGPFT
HHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCC
AEDGSRRARGVAMASPFGTETAVIAEVSIENGQVKVHDIWQAIDPGSIVNPAIVEAQVNG
CCCCCCHHCCEEEECCCCCCEEEEEEEEECCCEEEEEEHHHHCCCCCCCCCCEEEEECCC
AVALGLSQTLVEEAVWVDGKPRARNYDLYPILPPARMARVHVRVVESGEKMGGIGEPPLP
EEEECHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHEEEEEEECCCCCCCCCCCCCC
AVAPAVANAVATLTGQRVRSLPLSRHTFT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]