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The map label for this gene is arsR [H]

Identifier: 77458627

GI number: 77458627

Start: 2761965

End: 2762312

Strand: Reverse

Name: arsR [H]

Synonym: Pfl01_2400

Alternate gene names: 77458627

Gene position: 2762312-2761965 (Counterclockwise)

Preceding gene: 77458628

Following gene: 77458626

Centisome position: 42.9

GC content: 63.51

Gene sequence:

>348_bases
ATGCTCAACCCCGCCTCCGTTTTCAAATGCCTCGCCGACGAAACCCGCGCCCGGGCCACGCTGCTGATCACCCGTGAGGG
TGAGCTGTGTGTCTGCGAACTGGTCTGCGCGCTGGACGACAGTCAGCCGAAAATCTCCCGCCATCTCGCGCAGCTGCGCA
CCTGCGGTCTGCTGCTGGATCGTCGTCAGGGCCAGTGGGTTTATTACCGGCTCAACCCTGATTTGCCCGCATGGATTCGC
ACGCTGCTTGAAACCACGCTCGCCGCCAACACCGTCTGGCTGGAAGAGAACAGCGCGCGGCTGGCGGCCATGGGCGATCG
CCCGCTCAACACCTCTGCTTGCTGCTAA

Upstream 100 bases:

>100_bases
CACCCTCAGTCGAGAGCTGCCACTTCATCAAACTCAAGACTTGCCCAATACATATGGATATCCGTATATTCGGAAAACCA
TATGTACTGAAGGCATCCAC

Downstream 100 bases:

>100_bases
GCCTCAGGCTTTCGGGATTCCCATGTTTTTTGCTTTTGCCATTTTTCTATTCACGATTGTGCTGGTCATCTGGCAGCCGA
AGGGGCTGGGTGTCGGCTGG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MLNPASVFKCLADETRARATLLITREGELCVCELVCALDDSQPKISRHLAQLRTCGLLLDRRQGQWVYYRLNPDLPAWIR
TLLETTLAANTVWLEENSARLAAMGDRPLNTSACC

Sequences:

>Translated_115_residues
MLNPASVFKCLADETRARATLLITREGELCVCELVCALDDSQPKISRHLAQLRTCGLLLDRRQGQWVYYRLNPDLPAWIR
TLLETTLAANTVWLEENSARLAAMGDRPLNTSACC
>Mature_115_residues
MLNPASVFKCLADETRARATLLITREGELCVCELVCALDDSQPKISRHLAQLRTCGLLLDRRQGQWVYYRLNPDLPAWIR
TLLETTLAANTVWLEENSARLAAMGDRPLNTSACC

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=84, Percent_Identity=60.7142857142857, Blast_Score=107, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12905; Mature: 12905

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPASVFKCLADETRARATLLITREGELCVCELVCALDDSQPKISRHLAQLRTCGLLLD
CCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEHHEECCCCCCHHHHHHHHHHHHHHHHEE
RRQGQWVYYRLNPDLPAWIRTLLETTLAANTVWLEENSARLAAMGDRPLNTSACC
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLNPASVFKCLADETRARATLLITREGELCVCELVCALDDSQPKISRHLAQLRTCGLLLD
CCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEHHEECCCCCCHHHHHHHHHHHHHHHHEE
RRQGQWVYYRLNPDLPAWIRTLLETTLAANTVWLEENSARLAAMGDRPLNTSACC
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]