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The map label for this gene is aldH [H]

Identifier: 77458533

GI number: 77458533

Start: 2659386

End: 2660978

Strand: Reverse

Name: aldH [H]

Synonym: Pfl01_2306

Alternate gene names: 77458533

Gene position: 2660978-2659386 (Counterclockwise)

Preceding gene: 77458534

Following gene: 77458532

Centisome position: 41.33

GC content: 65.73

Gene sequence:

>1593_bases
ATGACTCTGACGGGCCAACTGCTGATCGGTCAGCAAACCCTCACCGGCGACCGCGACGTCATCCACGGGATCAATCCCGC
CACCAACCTGCCTTTGGAGCCGGCCTACGCCGGCGGCTCTGCCGAGCATGTCGAGCAGGCCTGCGCACTGGCCTGGGCCG
CGCTCGACTGTTATCGCGAGACATCGCTCGAGGCACGGGCGGAATTCATTGAAACCATCGCGGGCGAAATCGAAGCGCTG
GGCGACGAACTGATCGACCGCGCCCTGGCCGAAACCGGCCTGCCGCGCCCGCGCCTGCTGGGAGAACGGGGCCGCACCTG
TCAGCAACTGCGCTTGTTTGCCCACACCGTGCGGGCCGGTGAATGGCTGGATGTGCGAGTCGACACCGCGCAACCGCAAC
GCCAGCCAATGCCGCGTTCGGATCTGCGTCAGCGCCAGATTCCACTGGGCCCGGTGGCGGTGTTTGGCGCGAGCAACTTT
CCACTGGCGTTCTCGGTGGCCGGTGGCGATACCGCGTCGGCGCTGGCCGCCGGCTGCCCGGTGATCGTCAAGGCCCACGG
CGCCCATCCCGGTACCAGCGAACTGGTCGGCCGCGCGGTCGCGCGGGCGGTCAAGGCCTGTGGTTTGCCGGAAGGTGTGT
TCTCGTTGCTCTACGGTTCGGGCCGTGAAGTGGGGATTGCGCTGGTCAGCGATCCACGGATCAAGGCAGTCGGCTTCACC
GGTTCGCGCACCGGCGGGCTCGCGCTGATCAAGGCTGCTCAGGCCCGGCCCGAGCCGATTCCGGTGTATGCGGAAATGAG
TTCGATCAACCCGGTGTTGCTGTTTCCGGCAGCTCTGCAAAATCGCGCCGAGGCATTGGCCCAGGGTTTTGTGGCTTCGC
TGACATTGGGCGCCGGTCAGTTCTGCACCAATCCCGGTCTGGTCATCGCTCGCAAGGGGCCGACGCTGGACGCTTTCATT
GGCGCAGCCAGCGAACTGATCCAGCGCAGTCCCGCGCAGACCATGCTCACGCCGGGAATTTTCAACGCCTACGAATCCAG
CGTGAATGCCCTCGCGGAAAATACCCGGGCGCGTATTGCCGCCGTCGGCCAGCGCGCGTCGGATCCGAATCAGGGCCAGG
CTCATGTGTTCGTCACCGACGCCGCCGACTTCCTCGCCGATCATTCGTTGCAGGCCGAAGCCTTCGGCGCCGCCTCCTTG
ATCGTGCAATGCGCCAGCGACGCTGAAATCCGTCAGGTGCTCGAACAGCTGGAAGGCCAACTGACCGCCACGCTGCACCT
GGATGACGAGGACTTGGAACAGGCCCGCGCCTTGCTGCCGACCCTGGAGCGCAAGGCCGGACGCCTGCTGGTCAACGGCT
GGCCGACCGGCGTTGAAGTCTGCGATGCGATGGTGCATGGCGGGCCGTTCCCGGCGACCTCCGATTCGCGCACCACCTCG
GTGGGCACGGCGGCGATCCTGCGTTTCCTGCGCCCGGTCTGCTATCAGGATTTCCCCGACAGCCTGCTGCCGTCCGCGCT
CAAACACGCCAATCCACTGTCGCTGCGTCGCTTGCTCGATGGCCAAAGGGAAACCGCGAAAAATGCCGAATAA

Upstream 100 bases:

>100_bases
GGCGCAGCAGAACTTCGCCTGACCTGCCGCCCCGCTCAAGCCCGCCGCCCCGCGGCGGCGGGCCTTATTCGTGACCTGCT
TTATTGATAAGGAATGCGCC

Downstream 100 bases:

>100_bases
CCCGTACGACATCGCCGTGGTCGGCGCCGGCATCATCGGTGTCGCGAGTGCCCTGCGCCTGGCCCGTCAGGGTTTGCGGG
TGGTGGTGATCGACCCGCAG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTLTGQLLIGQQTLTGDRDVIHGINPATNLPLEPAYAGGSAEHVEQACALAWAALDCYRETSLEARAEFIETIAGEIEAL
GDELIDRALAETGLPRPRLLGERGRTCQQLRLFAHTVRAGEWLDVRVDTAQPQRQPMPRSDLRQRQIPLGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAVARAVKACGLPEGVFSLLYGSGREVGIALVSDPRIKAVGFT
GSRTGGLALIKAAQARPEPIPVYAEMSSINPVLLFPAALQNRAEALAQGFVASLTLGAGQFCTNPGLVIARKGPTLDAFI
GAASELIQRSPAQTMLTPGIFNAYESSVNALAENTRARIAAVGQRASDPNQGQAHVFVTDAADFLADHSLQAEAFGAASL
IVQCASDAEIRQVLEQLEGQLTATLHLDDEDLEQARALLPTLERKAGRLLVNGWPTGVEVCDAMVHGGPFPATSDSRTTS
VGTAAILRFLRPVCYQDFPDSLLPSALKHANPLSLRRLLDGQRETAKNAE

Sequences:

>Translated_530_residues
MTLTGQLLIGQQTLTGDRDVIHGINPATNLPLEPAYAGGSAEHVEQACALAWAALDCYRETSLEARAEFIETIAGEIEAL
GDELIDRALAETGLPRPRLLGERGRTCQQLRLFAHTVRAGEWLDVRVDTAQPQRQPMPRSDLRQRQIPLGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAVARAVKACGLPEGVFSLLYGSGREVGIALVSDPRIKAVGFT
GSRTGGLALIKAAQARPEPIPVYAEMSSINPVLLFPAALQNRAEALAQGFVASLTLGAGQFCTNPGLVIARKGPTLDAFI
GAASELIQRSPAQTMLTPGIFNAYESSVNALAENTRARIAAVGQRASDPNQGQAHVFVTDAADFLADHSLQAEAFGAASL
IVQCASDAEIRQVLEQLEGQLTATLHLDDEDLEQARALLPTLERKAGRLLVNGWPTGVEVCDAMVHGGPFPATSDSRTTS
VGTAAILRFLRPVCYQDFPDSLLPSALKHANPLSLRRLLDGQRETAKNAE
>Mature_529_residues
TLTGQLLIGQQTLTGDRDVIHGINPATNLPLEPAYAGGSAEHVEQACALAWAALDCYRETSLEARAEFIETIAGEIEALG
DELIDRALAETGLPRPRLLGERGRTCQQLRLFAHTVRAGEWLDVRVDTAQPQRQPMPRSDLRQRQIPLGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAVARAVKACGLPEGVFSLLYGSGREVGIALVSDPRIKAVGFTG
SRTGGLALIKAAQARPEPIPVYAEMSSINPVLLFPAALQNRAEALAQGFVASLTLGAGQFCTNPGLVIARKGPTLDAFIG
AASELIQRSPAQTMLTPGIFNAYESSVNALAENTRARIAAVGQRASDPNQGQAHVFVTDAADFLADHSLQAEAFGAASLI
VQCASDAEIRQVLEQLEGQLTATLHLDDEDLEQARALLPTLERKAGRLLVNGWPTGVEVCDAMVHGGPFPATSDSRTTSV
GTAAILRFLRPVCYQDFPDSLLPSALKHANPLSLRRLLDGQRETAKNAE

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=276, Percent_Identity=27.8985507246377, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI25777721, Length=285, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788042, Length=346, Percent_Identity=30.3468208092486, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787250, Length=323, Percent_Identity=29.1021671826625, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081896, Length=363, Percent_Identity=26.1707988980716, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787715, Length=328, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786504, Length=165, Percent_Identity=34.5454545454545, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787558, Length=498, Percent_Identity=25.7028112449799, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789015, Length=338, Percent_Identity=26.0355029585799, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71995606, Length=274, Percent_Identity=26.6423357664234, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995613, Length=274, Percent_Identity=26.6423357664234, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25143874, Length=168, Percent_Identity=31.547619047619, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323822, Length=318, Percent_Identity=26.7295597484277, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55965; Mature: 55834

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTGQLLIGQQTLTGDRDVIHGINPATNLPLEPAYAGGSAEHVEQACALAWAALDCYRE
CCEECCEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TSLEARAEFIETIAGEIEALGDELIDRALAETGLPRPRLLGERGRTCQQLRLFAHTVRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCC
EWLDVRVDTAQPQRQPMPRSDLRQRQIPLGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VIVKAHGAHPGTSELVGRAVARAVKACGLPEGVFSLLYGSGREVGIALVSDPRIKAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECC
GSRTGGLALIKAAQARPEPIPVYAEMSSINPVLLFPAALQNRAEALAQGFVASLTLGAGQ
CCCCCCCCEEEHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
FCTNPGLVIARKGPTLDAFIGAASELIQRSPAQTMLTPGIFNAYESSVNALAENTRARIA
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVGQRASDPNQGQAHVFVTDAADFLADHSLQAEAFGAASLIVQCASDAEIRQVLEQLEGQ
HHCCCCCCCCCCCEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
LTATLHLDDEDLEQARALLPTLERKAGRLLVNGWPTGVEVCDAMVHGGPFPATSDSRTTS
EEEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCH
VGTAAILRFLRPVCYQDFPDSLLPSALKHANPLSLRRLLDGQRETAKNAE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure 
TLTGQLLIGQQTLTGDRDVIHGINPATNLPLEPAYAGGSAEHVEQACALAWAALDCYRE
CEECCEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TSLEARAEFIETIAGEIEALGDELIDRALAETGLPRPRLLGERGRTCQQLRLFAHTVRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCC
EWLDVRVDTAQPQRQPMPRSDLRQRQIPLGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VIVKAHGAHPGTSELVGRAVARAVKACGLPEGVFSLLYGSGREVGIALVSDPRIKAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECC
GSRTGGLALIKAAQARPEPIPVYAEMSSINPVLLFPAALQNRAEALAQGFVASLTLGAGQ
CCCCCCCCEEEHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
FCTNPGLVIARKGPTLDAFIGAASELIQRSPAQTMLTPGIFNAYESSVNALAENTRARIA
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVGQRASDPNQGQAHVFVTDAADFLADHSLQAEAFGAASLIVQCASDAEIRQVLEQLEGQ
HHCCCCCCCCCCCEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
LTATLHLDDEDLEQARALLPTLERKAGRLLVNGWPTGVEVCDAMVHGGPFPATSDSRTTS
EEEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCH
VGTAAILRFLRPVCYQDFPDSLLPSALKHANPLSLRRLLDGQRETAKNAE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]