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The map label for this gene is hchA [H]

Identifier: 77458473

GI number: 77458473

Start: 2576822

End: 2577700

Strand: Direct

Name: hchA [H]

Synonym: Pfl01_2246

Alternate gene names: 77458473

Gene position: 2576822-2577700 (Clockwise)

Preceding gene: 77458471

Following gene: 77458474

Centisome position: 40.02

GC content: 60.18

Gene sequence:

>879_bases
ATGGCTACCACGCAGACTGACGACAAGCGCCCAACCCCCGATCCGGCCGAGGACAACGCGTTTTTCCCCTCGCCATATTC
CCTCAGCCAGTTCACTTCGCCCAAATCCGATCTCAGTGATGCCGAGTACCCGAACCGTTACAAGGGCGGGCGCTGGAAGG
TCCTGATGATCGGCGCGGACGAGCGCTATCTGTTGACCGACAACGGCACCATGTTCTCCACGGGCAATCACCCGGTTGAA
ACGCTGCTGCCGATGTATCACCTCGACAAGGCCGGTTTTGGCTTTGATGTCGCGACGCTGTCGGGCAATCCGGTCAAGTT
CGAATTCTGGGCCATGCCCTCCGAAGACGCCGAAGTGAAGGGCTTCTACGAGCAATACCGCGATCAGTTCAAGCGTCCAC
TCAAGCTGTCCCAGGTGATCGAAGAAGCGCTGGGCGAGGACTCTGATTACATCGGCGTGTTCATTCCCGGCGGCCACGGC
GCGCTGATCGGCCTGCCGGAAAGCGAGGACGTGAAAAAGATCCTGCAATGGGCAATCGCCAAGGACAAATTCGTCATTAC
CCTGTGCCACGGCCCGGCGGCGCTGCTGGCGGCCGGCCTCGGTGAAACAAAAGACTCATGCATCTTCAACGGTTACCGGA
TTTGCGCCTTTCCCGATGCCCTGGACTCTACAACCCCCGACATCGGTTACATGCCCGGCCACCTGACCTGGAAATTCGGC
GAGCAGTTGCAGGCGCTCGGTGTGGAAATCACTAACCAGGACATTTCCGGGGCCACGCTTCAGGATCGCAAACTGCTGAC
CGGTGACAGTCCGCTGGCGGGCAACGCACTGGGCAAACTGGCGGCCGCCGCGCTCCTCAAAGAGGTCACGTCGGGGTGA

Upstream 100 bases:

>100_bases
AGGTTCAGTGCATGATCTTTTGAGGGAAAACCCTCATTGTTGTAACGCTGACGCCTTACTAGCATGAACTCCGACGTTGA
CCCACTCGATGGAGAGCACC

Downstream 100 bases:

>100_bases
GCTCCGGACCTGCCGAAGCACTCTTGCGCGCCGCCCTCGACATCGAGGCGGCGCCCACGCTGGTGGCGATCCAGAAGGCC
GTTCGCGGTTTCGCCGGGGC

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MATTQTDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSDAEYPNRYKGGRWKVLMIGADERYLLTDNGTMFSTGNHPVE
TLLPMYHLDKAGFGFDVATLSGNPVKFEFWAMPSEDAEVKGFYEQYRDQFKRPLKLSQVIEEALGEDSDYIGVFIPGGHG
ALIGLPESEDVKKILQWAIAKDKFVITLCHGPAALLAAGLGETKDSCIFNGYRICAFPDALDSTTPDIGYMPGHLTWKFG
EQLQALGVEITNQDISGATLQDRKLLTGDSPLAGNALGKLAAAALLKEVTSG

Sequences:

>Translated_292_residues
MATTQTDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSDAEYPNRYKGGRWKVLMIGADERYLLTDNGTMFSTGNHPVE
TLLPMYHLDKAGFGFDVATLSGNPVKFEFWAMPSEDAEVKGFYEQYRDQFKRPLKLSQVIEEALGEDSDYIGVFIPGGHG
ALIGLPESEDVKKILQWAIAKDKFVITLCHGPAALLAAGLGETKDSCIFNGYRICAFPDALDSTTPDIGYMPGHLTWKFG
EQLQALGVEITNQDISGATLQDRKLLTGDSPLAGNALGKLAAAALLKEVTSG
>Mature_291_residues
ATTQTDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSDAEYPNRYKGGRWKVLMIGADERYLLTDNGTMFSTGNHPVET
LLPMYHLDKAGFGFDVATLSGNPVKFEFWAMPSEDAEVKGFYEQYRDQFKRPLKLSQVIEEALGEDSDYIGVFIPGGHGA
LIGLPESEDVKKILQWAIAKDKFVITLCHGPAALLAAGLGETKDSCIFNGYRICAFPDALDSTTPDIGYMPGHLTWKFGE
QLQALGVEITNQDISGATLQDRKLLTGDSPLAGNALGKLAAAALLKEVTSG

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=284, Percent_Identity=61.9718309859155, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 31810; Mature: 31679

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTQTDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSDAEYPNRYKGGRWKVLMIGAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECC
ERYLLTDNGTMFSTGNHPVETLLPMYHLDKAGFGFDVATLSGNPVKFEFWAMPSEDAEVK
CEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCHHH
GFYEQYRDQFKRPLKLSQVIEEALGEDSDYIGVFIPGGHGALIGLPESEDVKKILQWAIA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHC
KDKFVITLCHGPAALLAAGLGETKDSCIFNGYRICAFPDALDSTTPDIGYMPGHLTWKFG
CCCEEEEEECCHHHHHHHCCCCCCCCEEECCEEEEECCCHHCCCCCCCCCCCCCEEEHHH
EQLQALGVEITNQDISGATLQDRKLLTGDSPLAGNALGKLAAAALLKEVTSG
HHHHHHCCEEECCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTQTDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSDAEYPNRYKGGRWKVLMIGAD
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECC
ERYLLTDNGTMFSTGNHPVETLLPMYHLDKAGFGFDVATLSGNPVKFEFWAMPSEDAEVK
CEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCHHH
GFYEQYRDQFKRPLKLSQVIEEALGEDSDYIGVFIPGGHGALIGLPESEDVKKILQWAIA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHC
KDKFVITLCHGPAALLAAGLGETKDSCIFNGYRICAFPDALDSTTPDIGYMPGHLTWKFG
CCCEEEEEECCHHHHHHHCCCCCCCCEEECCEEEEECCCHHCCCCCCCCCCCCCEEEHHH
EQLQALGVEITNQDISGATLQDRKLLTGDSPLAGNALGKLAAAALLKEVTSG
HHHHHHCCEEECCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA