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The map label for this gene is iorB [H]

Identifier: 77458401

GI number: 77458401

Start: 2454579

End: 2456741

Strand: Direct

Name: iorB [H]

Synonym: Pfl01_2174

Alternate gene names: 77458401

Gene position: 2454579-2456741 (Clockwise)

Preceding gene: 77458400

Following gene: 77458402

Centisome position: 38.12

GC content: 63.85

Gene sequence:

>2163_bases
ATGAATAGTCCAGTATCCCGTCGCGGATTTCTCAAGGGCAGCGCCGTGCTGGGCGGTGGTCTGGTGGTGGCGTTCGTGGT
GCCTGGCGGCAACCGCTTTGCCATGGCGGCCGAGAATGAAGGCAAGGTGTTTGCGCCGAACGCGTTCCTGCGGATTGCAG
CGGACAACAGCGTGACCGTGCTGCTCGGCCATTCGGAAATGGGCCAGGGCATCTGGACCGGCCTGACCATGTTGATCGCC
GAAGAGCTGGACGCCGACTGGTCGAAAATCCGCGTCGAGCATTCCCCGGCTTCGGCCGCCGATTACGGCATGCCGGCGTT
TGGCGGGATGCAGATTACCGGCGGCTCCACTTCAACCTGGATGGAATTCGACCGTTACCGGCTCGCCGGCGCCACCGCCC
GGCAGATGCTGATCGAGGCGGCGGCCAAGCGCTTCAACGTGGCGCCGTCGACAATCCGCACCGAATCCGGCGTGGTGATT
GCCGGCGACAACCGCGCCACCTACGGCGAACTGGCGGACGCCGCCGGGCAACTGCCGGTGCCGGATCCGAAGTCGATCAC
CTTTAAAGAAGCCAAGGACTGGAAAGTCATCGGCAAACCCACCAAACGCCTCGACACCCCGGAAAAAATCACCGGTCGCG
CCAAGTTCGGTATGGACGTGCAGTTTGAGGGATTGATGACGGCGATGGTCGCTAGGGCGCCGACGTTTGGCGCCACGGTG
AAATCCTTTGAAGGCGCTGATGCGTTGGCGATCCCCGGCGTGCACAAAGTGGTGCAAGTGCCGACCGGTGTAGCCGTGGT
CGCCGAGCATTACTGGGCGGCGAAACTGGGGCGCGATGCGCTGAAGGTCGATTGGGACCTGGGGCCGAACGCTGATTTGA
GCAGTGAAAAGCTGTTGGCGAGTTTCCGCAAACTGGCGGCCACCCCGGGCACCTCGGCGGCGCAGGCCGGCGATGCCAAG
GGCAACTTCGGCAAGGCAGCGAAGAAAATCGATGTCGAATACAGTGTGCCGTACCTGGCCCACGCGCCGATGGAGCCGCT
CAACTGCACGGTGAAGATCAGCGCCGACAAGTGCGAGATCTGGACCGGCACCCAGTTCCAGACCCTGGATCAGATGGTTG
CCGGCAAGATCACCGGGCTCAAGCCGGAACAGGTCGAGATTCACACCGAATTCCTTGGCGGCGGGTTTGGTCGGCGGGCC
AACCCGACCTCGGATTTTGTCGCCGAAGCGGTGCAAGTGGCCAAGGCTGCCGCGATGCCGGTGAAAACCGTGTGGTCGCG
CGAAGACGATATTCGCGGTGGTTATTACCGCTCGATGTTCCTGCATCAGGCGAAGATCGGCCTCGGCGCCGACGGCCTGC
CGCTGGCATGGCAGCATGTGCTGGTCGGGCAATCGATCATGGCCGGCACCATGCTCGAGAAAACCATGGTCAAGAACGGC
GTCGACCAGACCTCGGTCGAGGGCGTTTCGGACAGCCCGTACATCAAGGGCCTGGCCCATCATCAGGTCGATCTGCACTC
GCCGAGCACCGGGATCAACGTGCTGTGGCTACGCTCGGTGGGCCATAGCCACACCGCGTTTGTCATGGAGTCGCTGATCG
ATGAAATGGCCACGGCGGCGGGCCAGGATCCGGTGGAGTACCGACGAACGCTGCTCAAGGAGCATGCCCGGCATCTCGGC
GTGTTGAACCTGGCGGTGGAGAAGGCTAACTGGAAAGCCCCGCTGCCGGACGGCCATGCGCTGGGCGTGGCGGTGCACGA
ATCGTTCGGCAGTTACGTGGCGCAGGTGGCCGAGGTGTCCCAGGACAATCTGGCGATCCGCGTGCATCGCGTGGTGTGCG
CGGTGGACTGCGGAGTGGCGGTGAACCCGCAGAGCATCGCGGCGCAGATGGAGTCGTGTATCACCTTCGGCCTGGGCATG
GCGCTGCACAGCAAACTGACCCTCAAGGACGGCCATGTCGTGCAGTCCAACTATCACGACTATCAGGTGTTGCGGCTCAA
TGAAATGCCGCTGGTCGAGGTGCACATCGTGCCCAGCAGCGAGAAACCCGGCGGCATCGGCGAGGCCGGTGTGCCGCCCA
CGGCGCCGGCGGTGGCCAACGCGGTGTTCGCCCTGACCGGGCAACGCCTGCGGGAACTGCCGCTGCAACTGTCGGGGGTG
TGA

Upstream 100 bases:

>100_bases
AGGCGCTCTCCGGCAATATCTGCCGCTGCGGCACGTATCCAAGAATCCGCGCGGCGGTCAAACGTGCTGCCGACATCGGC
TGAACGAAGGGAGGTGGGTG

Downstream 100 bases:

>100_bases
GATGAAACGACATCTGTTGTTGGGCACGGTGATTCTGCTTGGGCTGGGCGGTTACGCGTCGGATCTGTTTGCCGACGATC
AGGAAGCCTTGAAAGCTTTC

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MNSPVSRRGFLKGSAVLGGGLVVAFVVPGGNRFAMAAENEGKVFAPNAFLRIAADNSVTVLLGHSEMGQGIWTGLTMLIA
EELDADWSKIRVEHSPASAADYGMPAFGGMQITGGSTSTWMEFDRYRLAGATARQMLIEAAAKRFNVAPSTIRTESGVVI
AGDNRATYGELADAAGQLPVPDPKSITFKEAKDWKVIGKPTKRLDTPEKITGRAKFGMDVQFEGLMTAMVARAPTFGATV
KSFEGADALAIPGVHKVVQVPTGVAVVAEHYWAAKLGRDALKVDWDLGPNADLSSEKLLASFRKLAATPGTSAAQAGDAK
GNFGKAAKKIDVEYSVPYLAHAPMEPLNCTVKISADKCEIWTGTQFQTLDQMVAGKITGLKPEQVEIHTEFLGGGFGRRA
NPTSDFVAEAVQVAKAAAMPVKTVWSREDDIRGGYYRSMFLHQAKIGLGADGLPLAWQHVLVGQSIMAGTMLEKTMVKNG
VDQTSVEGVSDSPYIKGLAHHQVDLHSPSTGINVLWLRSVGHSHTAFVMESLIDEMATAAGQDPVEYRRTLLKEHARHLG
VLNLAVEKANWKAPLPDGHALGVAVHESFGSYVAQVAEVSQDNLAIRVHRVVCAVDCGVAVNPQSIAAQMESCITFGLGM
ALHSKLTLKDGHVVQSNYHDYQVLRLNEMPLVEVHIVPSSEKPGGIGEAGVPPTAPAVANAVFALTGQRLRELPLQLSGV

Sequences:

>Translated_720_residues
MNSPVSRRGFLKGSAVLGGGLVVAFVVPGGNRFAMAAENEGKVFAPNAFLRIAADNSVTVLLGHSEMGQGIWTGLTMLIA
EELDADWSKIRVEHSPASAADYGMPAFGGMQITGGSTSTWMEFDRYRLAGATARQMLIEAAAKRFNVAPSTIRTESGVVI
AGDNRATYGELADAAGQLPVPDPKSITFKEAKDWKVIGKPTKRLDTPEKITGRAKFGMDVQFEGLMTAMVARAPTFGATV
KSFEGADALAIPGVHKVVQVPTGVAVVAEHYWAAKLGRDALKVDWDLGPNADLSSEKLLASFRKLAATPGTSAAQAGDAK
GNFGKAAKKIDVEYSVPYLAHAPMEPLNCTVKISADKCEIWTGTQFQTLDQMVAGKITGLKPEQVEIHTEFLGGGFGRRA
NPTSDFVAEAVQVAKAAAMPVKTVWSREDDIRGGYYRSMFLHQAKIGLGADGLPLAWQHVLVGQSIMAGTMLEKTMVKNG
VDQTSVEGVSDSPYIKGLAHHQVDLHSPSTGINVLWLRSVGHSHTAFVMESLIDEMATAAGQDPVEYRRTLLKEHARHLG
VLNLAVEKANWKAPLPDGHALGVAVHESFGSYVAQVAEVSQDNLAIRVHRVVCAVDCGVAVNPQSIAAQMESCITFGLGM
ALHSKLTLKDGHVVQSNYHDYQVLRLNEMPLVEVHIVPSSEKPGGIGEAGVPPTAPAVANAVFALTGQRLRELPLQLSGV
>Mature_720_residues
MNSPVSRRGFLKGSAVLGGGLVVAFVVPGGNRFAMAAENEGKVFAPNAFLRIAADNSVTVLLGHSEMGQGIWTGLTMLIA
EELDADWSKIRVEHSPASAADYGMPAFGGMQITGGSTSTWMEFDRYRLAGATARQMLIEAAAKRFNVAPSTIRTESGVVI
AGDNRATYGELADAAGQLPVPDPKSITFKEAKDWKVIGKPTKRLDTPEKITGRAKFGMDVQFEGLMTAMVARAPTFGATV
KSFEGADALAIPGVHKVVQVPTGVAVVAEHYWAAKLGRDALKVDWDLGPNADLSSEKLLASFRKLAATPGTSAAQAGDAK
GNFGKAAKKIDVEYSVPYLAHAPMEPLNCTVKISADKCEIWTGTQFQTLDQMVAGKITGLKPEQVEIHTEFLGGGFGRRA
NPTSDFVAEAVQVAKAAAMPVKTVWSREDDIRGGYYRSMFLHQAKIGLGADGLPLAWQHVLVGQSIMAGTMLEKTMVKNG
VDQTSVEGVSDSPYIKGLAHHQVDLHSPSTGINVLWLRSVGHSHTAFVMESLIDEMATAAGQDPVEYRRTLLKEHARHLG
VLNLAVEKANWKAPLPDGHALGVAVHESFGSYVAQVAEVSQDNLAIRVHRVVCAVDCGVAVNPQSIAAQMESCITFGLGM
ALHSKLTLKDGHVVQSNYHDYQVLRLNEMPLVEVHIVPSSEKPGGIGEAGVPPTAPAVANAVFALTGQRLRELPLQLSGV

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=175, Percent_Identity=26.8571428571429, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 76732; Mature: 76732

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPVSRRGFLKGSAVLGGGLVVAFVVPGGNRFAMAAENEGKVFAPNAFLRIAADNSVTV
CCCCCCCCCCCCCCEEECCCEEEEEEECCCCEEEEEECCCCCEECCCCEEEEEECCCEEE
LLGHSEMGQGIWTGLTMLIAEELDADWSKIRVEHSPASAADYGMPAFGGMQITGGSTSTW
EECCCHHCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHCCCCCCCCEEEECCCCCHH
MEFDRYRLAGATARQMLIEAAAKRFNVAPSTIRTESGVVIAGDNRATYGELADAAGQLPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCCCHHHHHHHCCCCCC
PDPKSITFKEAKDWKVIGKPTKRLDTPEKITGRAKFGMDVQFEGLMTAMVARAPTFGATV
CCCCCEEECCCCCCEEECCCHHHCCCCHHHCCCEECCCCEEHHHHHHHHHHCCCCCCCHH
KSFEGADALAIPGVHKVVQVPTGVAVVAEHYWAAKLGRDALKVDWDLGPNADLSSEKLLA
HCCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHH
SFRKLAATPGTSAAQAGDAKGNFGKAAKKIDVEYSVPYLAHAPMEPLNCTVKISADKCEI
HHHHHHCCCCCCHHCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEECCCEEE
WTGTQFQTLDQMVAGKITGLKPEQVEIHTEFLGGGFGRRANPTSDFVAEAVQVAKAAAMP
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
VKTVWSREDDIRGGYYRSMFLHQAKIGLGADGLPLAWQHVLVGQSIMAGTMLEKTMVKNG
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
VDQTSVEGVSDSPYIKGLAHHQVDLHSPSTGINVLWLRSVGHSHTAFVMESLIDEMATAA
CCCCCCCCCCCCCHHCCHHHCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
GQDPVEYRRTLLKEHARHLGVLNLAVEKANWKAPLPDGHALGVAVHESFGSYVAQVAEVS
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCC
QDNLAIRVHRVVCAVDCGVAVNPQSIAAQMESCITFGLGMALHSKLTLKDGHVVQSNYHD
CCCEEEEEEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEECCCCC
YQVLRLNEMPLVEVHIVPSSEKPGGIGEAGVPPTAPAVANAVFALTGQRLRELPLQLSGV
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MNSPVSRRGFLKGSAVLGGGLVVAFVVPGGNRFAMAAENEGKVFAPNAFLRIAADNSVTV
CCCCCCCCCCCCCCEEECCCEEEEEEECCCCEEEEEECCCCCEECCCCEEEEEECCCEEE
LLGHSEMGQGIWTGLTMLIAEELDADWSKIRVEHSPASAADYGMPAFGGMQITGGSTSTW
EECCCHHCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHCCCCCCCCEEEECCCCCHH
MEFDRYRLAGATARQMLIEAAAKRFNVAPSTIRTESGVVIAGDNRATYGELADAAGQLPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCCCHHHHHHHCCCCCC
PDPKSITFKEAKDWKVIGKPTKRLDTPEKITGRAKFGMDVQFEGLMTAMVARAPTFGATV
CCCCCEEECCCCCCEEECCCHHHCCCCHHHCCCEECCCCEEHHHHHHHHHHCCCCCCCHH
KSFEGADALAIPGVHKVVQVPTGVAVVAEHYWAAKLGRDALKVDWDLGPNADLSSEKLLA
HCCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHH
SFRKLAATPGTSAAQAGDAKGNFGKAAKKIDVEYSVPYLAHAPMEPLNCTVKISADKCEI
HHHHHHCCCCCCHHCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEECCCEEE
WTGTQFQTLDQMVAGKITGLKPEQVEIHTEFLGGGFGRRANPTSDFVAEAVQVAKAAAMP
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
VKTVWSREDDIRGGYYRSMFLHQAKIGLGADGLPLAWQHVLVGQSIMAGTMLEKTMVKNG
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCC
VDQTSVEGVSDSPYIKGLAHHQVDLHSPSTGINVLWLRSVGHSHTAFVMESLIDEMATAA
CCCCCCCCCCCCCHHCCHHHCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
GQDPVEYRRTLLKEHARHLGVLNLAVEKANWKAPLPDGHALGVAVHESFGSYVAQVAEVS
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCC
QDNLAIRVHRVVCAVDCGVAVNPQSIAAQMESCITFGLGMALHSKLTLKDGHVVQSNYHD
CCCEEEEEEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEECCCCC
YQVLRLNEMPLVEVHIVPSSEKPGGIGEAGVPPTAPAVANAVFALTGQRLRELPLQLSGV
EEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]