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The map label for this gene is iorA [H]

Identifier: 77458400

GI number: 77458400

Start: 2454106

End: 2454561

Strand: Direct

Name: iorA [H]

Synonym: Pfl01_2173

Alternate gene names: 77458400

Gene position: 2454106-2454561 (Clockwise)

Preceding gene: 77458398

Following gene: 77458401

Centisome position: 38.12

GC content: 63.82

Gene sequence:

>456_bases
ATGCTGACCTTGAATATCAATGGCAAGGATCAGGAGCTCGATGTCCCTGCGGACATGCCGTTGCTCTGGGTCCTGCGCGA
TGTCGCGCACCTGACCGGTACCAAATTCGGTTGCGGCATGGCCCAGTGCGGTGCCTGCACCGTGCACGTCGATGGCGCGC
CGTTGCGCTCGTGTATCACGCCGGCCACGGCCGTCGCCCATGGCCAGAAGATCCTCACCATCGAAGGCCTGTCGAGCGAC
GGCTCGCACCCGGTGCAGCAGGCCTGGGCCGAACTGGACGTGGTGCAATGCGGTTACTGCCAGTCCGGGCAGATCATGTC
CGCCGCCGCGTTGCTGGCGAAAATCCCCAAACCCACCGACAGCGATATCGATCAGGCGCTCTCCGGCAATATCTGCCGCT
GCGGCACGTATCCAAGAATCCGCGCGGCGGTCAAACGTGCTGCCGACATCGGCTGA

Upstream 100 bases:

>100_bases
GCAAAATGCGCTTAGCTGAAAGGGATAAGCCGAGGCGCGCACCGCCAACGATGGCCGTAGCAGCGCCCTTCAGAACACTG
TGAGTCTGAGGAAGTCCCCG

Downstream 100 bases:

>100_bases
ACGAAGGGAGGTGGGTGATGAATAGTCCAGTATCCCGTCGCGGATTTCTCAAGGGCAGCGCCGTGCTGGGCGGTGGTCTG
GTGGTGGCGTTCGTGGTGCC

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MLTLNINGKDQELDVPADMPLLWVLRDVAHLTGTKFGCGMAQCGACTVHVDGAPLRSCITPATAVAHGQKILTIEGLSSD
GSHPVQQAWAELDVVQCGYCQSGQIMSAAALLAKIPKPTDSDIDQALSGNICRCGTYPRIRAAVKRAADIG

Sequences:

>Translated_151_residues
MLTLNINGKDQELDVPADMPLLWVLRDVAHLTGTKFGCGMAQCGACTVHVDGAPLRSCITPATAVAHGQKILTIEGLSSD
GSHPVQQAWAELDVVQCGYCQSGQIMSAAALLAKIPKPTDSDIDQALSGNICRCGTYPRIRAAVKRAADIG
>Mature_151_residues
MLTLNINGKDQELDVPADMPLLWVLRDVAHLTGTKFGCGMAQCGACTVHVDGAPLRSCITPATAVAHGQKILTIEGLSSD
GSHPVQQAWAELDVVQCGYCQSGQIMSAAALLAKIPKPTDSDIDQALSGNICRCGTYPRIRAAVKRAADIG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=94, Percent_Identity=38.2978723404255, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI91823271, Length=83, Percent_Identity=38.5542168674699, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=47.5609756097561, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1789232, Length=144, Percent_Identity=44.4444444444444, Blast_Score=94, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=161, Percent_Identity=40.3726708074534, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.9084967320261, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=37.9084967320261, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=158, Percent_Identity=36.7088607594937, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=36.6459627329193, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=35.2564102564103, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=33.7423312883436, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=33.7423312883436, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647199, Length=142, Percent_Identity=35.9154929577465, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15857; Mature: 15857

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLNINGKDQELDVPADMPLLWVLRDVAHLTGTKFGCGMAQCGACTVHVDGAPLRSCIT
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHC
PATAVAHGQKILTIEGLSSDGSHPVQQAWAELDVVQCGYCQSGQIMSAAALLAKIPKPTD
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCHHCCCCCCCCCHHHHHHHHHHCCCCCC
SDIDQALSGNICRCGTYPRIRAAVKRAADIG
CCHHHHHCCCEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTLNINGKDQELDVPADMPLLWVLRDVAHLTGTKFGCGMAQCGACTVHVDGAPLRSCIT
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHC
PATAVAHGQKILTIEGLSSDGSHPVQQAWAELDVVQCGYCQSGQIMSAAALLAKIPKPTD
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCHHCCCCCCCCCHHHHHHHHHHCCCCCC
SDIDQALSGNICRCGTYPRIRAAVKRAADIG
CCHHHHHCCCEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]