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The map label for this gene is oxyR [H]

Identifier: 77458376

GI number: 77458376

Start: 2432184

End: 2433083

Strand: Reverse

Name: oxyR [H]

Synonym: Pfl01_2149

Alternate gene names: 77458376

Gene position: 2433083-2432184 (Counterclockwise)

Preceding gene: 77458379

Following gene: 77458375

Centisome position: 37.79

GC content: 61.33

Gene sequence:

>900_bases
GTGGACATCAAACAACTCAAGTTTCTGATCGCGCTGGACGAAACCCGCCACTTCGGCCAGGCCGCCGCGCGCTGTCACAT
CACCCAGCCGACCCTGTCGATGCGCCTGCGCAATCTGGAAGACGAGCTGGATCTGGTGCTGGTCAATCGCGGCCAGCGCT
TCGAAGGTTTCACCCAGGCCGGCGAGCGCGTCCTGGCCTGGGCCCGCACGTTGCTGGCGGCCCATGACGGGTTGTTTGCC
GAAGCGGCGGCCTGCCGCGGACAACTGGTGGGTAGCCTGCGCCTGGGGCTGGTGCCGCTGAGCAACTTCAATCCGGTGAA
TTACATTCAGGGTTTGTCAGGGATATTTCCCGAGCTGAAATACAGCCTGTCGTCGCTGAGTTCGGACGAGATCATCGAAG
GTCTGGGTAACAATCAGCTGGACTTGGGCGTGTGTTATCTGGACCACGTCAACCCGAACTATTTCGAGTTCTTCGAGATT
GGCGAAACCCGCGTCGGCCTGCTCTACGACACCCGTCACTTCCATTTCGAAGGCCCGGAAATGAGCTGGGAGGACGCCGC
CGAACTGCCGCTGGGGATGATCACTACCGGCATGCACTACCGCAAATCCATCGACCTGAGTTTCCGCAGTCGCGGACTCA
ATCCGCAGCCGATCCTGGAAAGCGACTCGACCTACCAACTGCTGCAGGCGATTCACCAAGGCTTCTGCTGCTCGATCATG
CCGCTGGACAGCGGTCTGGAAGAGCCGATCGAACACCTGGCCTTCATCAACCTGCCGGATGCCAGCGTGCTCGCGCCGCT
GGGGCTGGTGATGCGCAAGACCGAACCGCGCTCGGCGATCGCCGAGAAGTGTTTTGCCGAGGCGCGCAAGATGTTCGGGG
TCGAGGCGCCCGCCGTTTAA

Upstream 100 bases:

>100_bases
AAAAAATCCCTCAGTGGGATCGTCGCTCCCTGCGCTTTCCGTGCGCCGTACGCATCTGCGTCAATACTCAATCAAAATTC
TCAATCGAGCAGGTGCCGTC

Downstream 100 bases:

>100_bases
CCCTCCCCAAGTTGCCTGAAACGTTGCACTTCGGTGCAACGACTTCAGGTCCGCCTGCGGTCATCGACCAATCCAATCAC
TGCATCGGAACAAGCGATTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDIKQLKFLIALDETRHFGQAAARCHITQPTLSMRLRNLEDELDLVLVNRGQRFEGFTQAGERVLAWARTLLAAHDGLFA
EAAACRGQLVGSLRLGLVPLSNFNPVNYIQGLSGIFPELKYSLSSLSSDEIIEGLGNNQLDLGVCYLDHVNPNYFEFFEI
GETRVGLLYDTRHFHFEGPEMSWEDAAELPLGMITTGMHYRKSIDLSFRSRGLNPQPILESDSTYQLLQAIHQGFCCSIM
PLDSGLEEPIEHLAFINLPDASVLAPLGLVMRKTEPRSAIAEKCFAEARKMFGVEAPAV

Sequences:

>Translated_299_residues
MDIKQLKFLIALDETRHFGQAAARCHITQPTLSMRLRNLEDELDLVLVNRGQRFEGFTQAGERVLAWARTLLAAHDGLFA
EAAACRGQLVGSLRLGLVPLSNFNPVNYIQGLSGIFPELKYSLSSLSSDEIIEGLGNNQLDLGVCYLDHVNPNYFEFFEI
GETRVGLLYDTRHFHFEGPEMSWEDAAELPLGMITTGMHYRKSIDLSFRSRGLNPQPILESDSTYQLLQAIHQGFCCSIM
PLDSGLEEPIEHLAFINLPDASVLAPLGLVMRKTEPRSAIAEKCFAEARKMFGVEAPAV
>Mature_299_residues
MDIKQLKFLIALDETRHFGQAAARCHITQPTLSMRLRNLEDELDLVLVNRGQRFEGFTQAGERVLAWARTLLAAHDGLFA
EAAACRGQLVGSLRLGLVPLSNFNPVNYIQGLSGIFPELKYSLSSLSSDEIIEGLGNNQLDLGVCYLDHVNPNYFEFFEI
GETRVGLLYDTRHFHFEGPEMSWEDAAELPLGMITTGMHYRKSIDLSFRSRGLNPQPILESDSTYQLLQAIHQGFCCSIM
PLDSGLEEPIEHLAFINLPDASVLAPLGLVMRKTEPRSAIAEKCFAEARKMFGVEAPAV

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=158, Percent_Identity=35.4430379746835, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=23.0452674897119, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787879, Length=152, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=21.602787456446, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33314; Mature: 33314

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKQLKFLIALDETRHFGQAAARCHITQPTLSMRLRNLEDELDLVLVNRGQRFEGFTQA
CCHHHEEEEEEEHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHH
GERVLAWARTLLAAHDGLFAEAAACRGQLVGSLRLGLVPLSNFNPVNYIQGLSGIFPELK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
YSLSSLSSDEIIEGLGNNQLDLGVCYLDHVNPNYFEFFEIGETRVGLLYDTRHFHFEGPE
HHHHHCCHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCEEEECCCC
MSWEDAAELPLGMITTGMHYRKSIDLSFRSRGLNPQPILESDSTYQLLQAIHQGFCCSIM
CCCCHHHHCCHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
PLDSGLEEPIEHLAFINLPDASVLAPLGLVMRKTEPRSAIAEKCFAEARKMFGVEAPAV
ECCCCHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDIKQLKFLIALDETRHFGQAAARCHITQPTLSMRLRNLEDELDLVLVNRGQRFEGFTQA
CCHHHEEEEEEEHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHH
GERVLAWARTLLAAHDGLFAEAAACRGQLVGSLRLGLVPLSNFNPVNYIQGLSGIFPELK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
YSLSSLSSDEIIEGLGNNQLDLGVCYLDHVNPNYFEFFEIGETRVGLLYDTRHFHFEGPE
HHHHHCCHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCEEEECCCC
MSWEDAAELPLGMITTGMHYRKSIDLSFRSRGLNPQPILESDSTYQLLQAIHQGFCCSIM
CCCCHHHHCCHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
PLDSGLEEPIEHLAFINLPDASVLAPLGLVMRKTEPRSAIAEKCFAEARKMFGVEAPAV
ECCCCHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]