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The map label for this gene is moaC [H]

Identifier: 77458374

GI number: 77458374

Start: 2430699

End: 2431184

Strand: Reverse

Name: moaC [H]

Synonym: Pfl01_2147

Alternate gene names: 77458374

Gene position: 2431184-2430699 (Counterclockwise)

Preceding gene: 77458375

Following gene: 77458373

Centisome position: 37.76

GC content: 65.43

Gene sequence:

>486_bases
ATGAGCAACACCCTCACCCACCTCGACGATCAGGGCCGCGCCAACATGGTCGACGTCAGCGACAAAGCCGCGACCCGCCG
CGAAGCCACTGCCCAGGCCTGGGTGCAGATGCGTCCGCAAACCCTGCAAATGATCCAGTCCAACGGCCACCCCAAGGGCG
ATGTGTTCGCCGTGGCGCGGATCGCCGGGATTCAGGCCGCCAAGCGCACCCACGAGCTGATTCCGCTGTGCCATGCGCTG
TTGCTCAGCTCTATCCACGTCGAACTCAAGGCCTGTGAACCGGATCGCGTGCAGATCACCAGCACCTGCCGCCTCACCGG
CCAGACCGGGGTCGAACTCGAGGCCCTGACCGCCGCCAGCGTCGCCGCGCTGACCATCTACGACATGTGCAAGGCGGTGG
ACCGGGCGATGGTTATCGGCGACATCCGCCTGCTGAGCAAACAGGGCGGCCGCTCCGGCCACTTTCAATGGGAGAACCCG
CAATGA

Upstream 100 bases:

>100_bases
CACTTACGGTGCGCTGGGCGCTCAAGCACCGCCTGAACCTGATCCACGTCCCGCACCGCAATGCCCCGCGAGTCTACAGC
CCGATCCAGGAGCCCACCGC

Downstream 100 bases:

>100_bases
TTCTGATCAACTACTTCGCCAGCTACCGTGACCGGCTCAATCTGGGCGGTGAAAAGATTCCGGCCAGCGACACCCTCGCT
TGTGTCGAAGATGTGCGGCA

Product: molybdopterin cofactor biosynthesis MoaC region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSNTLTHLDDQGRANMVDVSDKAATRREATAQAWVQMRPQTLQMIQSNGHPKGDVFAVARIAGIQAAKRTHELIPLCHAL
LLSSIHVELKACEPDRVQITSTCRLTGQTGVELEALTAASVAALTIYDMCKAVDRAMVIGDIRLLSKQGGRSGHFQWENP
Q

Sequences:

>Translated_161_residues
MSNTLTHLDDQGRANMVDVSDKAATRREATAQAWVQMRPQTLQMIQSNGHPKGDVFAVARIAGIQAAKRTHELIPLCHAL
LLSSIHVELKACEPDRVQITSTCRLTGQTGVELEALTAASVAALTIYDMCKAVDRAMVIGDIRLLSKQGGRSGHFQWENP
Q
>Mature_160_residues
SNTLTHLDDQGRANMVDVSDKAATRREATAQAWVQMRPQTLQMIQSNGHPKGDVFAVARIAGIQAAKRTHELIPLCHALL
LSSIHVELKACEPDRVQITSTCRLTGQTGVELEALTAASVAALTIYDMCKAVDRAMVIGDIRLLSKQGGRSGHFQWENPQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=66.6666666666667, Blast_Score=199, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI32566331, Length=155, Percent_Identity=40.6451612903226, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=55.0632911392405, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=54.421768707483, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17572; Mature: 17441

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTLTHLDDQGRANMVDVSDKAATRREATAQAWVQMRPQTLQMIQSNGHPKGDVFAVAR
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
IAGIQAAKRTHELIPLCHALLLSSIHVELKACEPDRVQITSTCRLTGQTGVELEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCEEEHHHHHH
VAALTIYDMCKAVDRAMVIGDIRLLSKQGGRSGHFQWENPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNTLTHLDDQGRANMVDVSDKAATRREATAQAWVQMRPQTLQMIQSNGHPKGDVFAVAR
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
IAGIQAAKRTHELIPLCHALLLSSIHVELKACEPDRVQITSTCRLTGQTGVELEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCEEEHHHHHH
VAALTIYDMCKAVDRAMVIGDIRLLSKQGGRSGHFQWENPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA