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The map label for this gene is gatR [H]

Identifier: 77458368

GI number: 77458368

Start: 2424632

End: 2425417

Strand: Direct

Name: gatR [H]

Synonym: Pfl01_2141

Alternate gene names: 77458368

Gene position: 2424632-2425417 (Clockwise)

Preceding gene: 77458367

Following gene: 77458377

Centisome position: 37.66

GC content: 63.36

Gene sequence:

>786_bases
ATGCACGATCATTCCGCTTCCGAGCTTCCCTCCCTGCGCCGGCAGAAAATCCTTCTGATCCTCGAACGTGACGGCAAGGT
CATGGCGTCCGAGTTGAGCCAGCATTTTGCGGTGTCCGAAGACACCATCCGCCGCGATCTCGCCGAGCTGGACAACGCCG
GACTGGTGCAGCGAGTGCACGGCGGCGCGCTGCCGAGGCCCAAGGACACCGGCAAGGATTACTTCACCCGGCTGGACGAG
ATCGACGAGGTGAAAATCCGTCTGGCGCAATTGGCGGCGCAGCAGGTGCGCAACGGGCAGACGGTGATGTTCGACTCCGG
TTCCACCTCGTTGCAGGTGGCGCGTTCGTTGCCCAGGGACATCAGCCTCACGGCGGTCACAGCATCGCCGATGACGGCGA
TTGCGTTGTCCGAATACCCTGGCATCAAAGTGATTCTGGCGGGCGGGCAGCTCAATCCGAAAACCATGTCCGCCGGCGGT
CACGAGGCGCTGCGGCTGCTGTGGGGGATCAAGGCGGATCTGGCGATCACCGGGGTCTGCGCGATTCATCCGGAGGTGGG
CATCACCTCGCTGCATTTCGATGAAGTGCCGGTCAAACAGGCGCTGCTCGACTGTGCGACGCGGGTAATTGCCGTGACCA
CGGCGGATAAGCTCGGCGCGGTGGAGCCGTTTGTGGTGGCGCCGTGCGAGCGCTTGCACACGCTGATCACCGAACGGCAT
GTGGCGTCGGGGAGTGTCGAGGATTATCGGCGGTTGGGGATTGAGGTGGAGCAGTTGCCCGACTGA

Upstream 100 bases:

>100_bases
TGATTCCAATGATCGAAGCCATTGATACCTGCGTTGTGTTTACCGACCGGCTTGGCTAATCTCGCCAAACCTGCAACGAC
AAGCACAAACAGGCAAAACC

Downstream 100 bases:

>100_bases
GGTTTTGCGGCAAAAAAGACCCCATCACTGGCGATGGGGCCTGTTCGATCAGCGCAGTTTTTCCAGCATCTGGTAGTACC
ACATGCCGGCCGCCAGCATC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MHDHSASELPSLRRQKILLILERDGKVMASELSQHFAVSEDTIRRDLAELDNAGLVQRVHGGALPRPKDTGKDYFTRLDE
IDEVKIRLAQLAAQQVRNGQTVMFDSGSTSLQVARSLPRDISLTAVTASPMTAIALSEYPGIKVILAGGQLNPKTMSAGG
HEALRLLWGIKADLAITGVCAIHPEVGITSLHFDEVPVKQALLDCATRVIAVTTADKLGAVEPFVVAPCERLHTLITERH
VASGSVEDYRRLGIEVEQLPD

Sequences:

>Translated_261_residues
MHDHSASELPSLRRQKILLILERDGKVMASELSQHFAVSEDTIRRDLAELDNAGLVQRVHGGALPRPKDTGKDYFTRLDE
IDEVKIRLAQLAAQQVRNGQTVMFDSGSTSLQVARSLPRDISLTAVTASPMTAIALSEYPGIKVILAGGQLNPKTMSAGG
HEALRLLWGIKADLAITGVCAIHPEVGITSLHFDEVPVKQALLDCATRVIAVTTADKLGAVEPFVVAPCERLHTLITERH
VASGSVEDYRRLGIEVEQLPD
>Mature_261_residues
MHDHSASELPSLRRQKILLILERDGKVMASELSQHFAVSEDTIRRDLAELDNAGLVQRVHGGALPRPKDTGKDYFTRLDE
IDEVKIRLAQLAAQQVRNGQTVMFDSGSTSLQVARSLPRDISLTAVTASPMTAIALSEYPGIKVILAGGQLNPKTMSAGG
HEALRLLWGIKADLAITGVCAIHPEVGITSLHFDEVPVKQALLDCATRVIAVTTADKLGAVEPFVVAPCERLHTLITERH
VASGSVEDYRRLGIEVEQLPD

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=29.7619047619048, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789829, Length=207, Percent_Identity=31.4009661835749, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787063, Length=224, Percent_Identity=26.7857142857143, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790753, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=27.5109170305677, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=29.2372881355932, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082344, Length=226, Percent_Identity=25.6637168141593, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789170, Length=149, Percent_Identity=31.5436241610738, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28335; Mature: 28335

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDHSASELPSLRRQKILLILERDGKVMASELSQHFAVSEDTIRRDLAELDNAGLVQRVH
CCCCCCHHHHHHHHCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHC
GGALPRPKDTGKDYFTRLDEIDEVKIRLAQLAAQQVRNGQTVMFDSGSTSLQVARSLPRD
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCC
ISLTAVTASPMTAIALSEYPGIKVILAGGQLNPKTMSAGGHEALRLLWGIKADLAITGVC
CEEEEEECCCCEEEEECCCCCEEEEEECCCCCCHHCCCCHHHHHHHHHCCCCCCEEEEEE
AIHPEVGITSLHFDEVPVKQALLDCATRVIAVTTADKLGAVEPFVVAPCERLHTLITERH
EECCCCCCEEEECCCCCHHHHHHHHHHHEEEEEEHHHHCCCCCHHHCCHHHHHHHHHHHH
VASGSVEDYRRLGIEVEQLPD
HCCCCHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MHDHSASELPSLRRQKILLILERDGKVMASELSQHFAVSEDTIRRDLAELDNAGLVQRVH
CCCCCCHHHHHHHHCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHC
GGALPRPKDTGKDYFTRLDEIDEVKIRLAQLAAQQVRNGQTVMFDSGSTSLQVARSLPRD
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCC
ISLTAVTASPMTAIALSEYPGIKVILAGGQLNPKTMSAGGHEALRLLWGIKADLAITGVC
CEEEEEECCCCEEEEECCCCCEEEEEECCCCCCHHCCCCHHHHHHHHHCCCCCCEEEEEE
AIHPEVGITSLHFDEVPVKQALLDCATRVIAVTTADKLGAVEPFVVAPCERLHTLITERH
EECCCCCCEEEECCCCCHHHHHHHHHHHEEEEEEHHHHCCCCCHHHCCHHHHHHHHHHHH
VASGSVEDYRRLGIEVEQLPD
HCCCCHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]