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The map label for this gene is moaB [H]

Identifier: 77458377

GI number: 77458377

Start: 2433382

End: 2433921

Strand: Direct

Name: moaB [H]

Synonym: Pfl01_2150

Alternate gene names: 77458377

Gene position: 2433382-2433921 (Clockwise)

Preceding gene: 77458368

Following gene: 77458378

Centisome position: 37.79

GC content: 62.96

Gene sequence:

>540_bases
ATGAGTGTTAAATCGGATGCCTTGTTCGTTCCCCTGAATATTGCCGTGCTGACGGTCAGCGATACCCGCGATTACGCCAG
TGACACCTCCGGCCAGTTGCTGGTCAGCCGTCTGCTGGAGGCCGGCCACACCCTGAGCGAGCGCAACTTGCTCAAGGACG
ACCTGTACAAGATCCGCGCCCAGGTCGCGCACTGGATCGCCGACGACAACATTCAAGTGGTGCTGATCACCGGCGGCACC
GGTTTCACCGGCCGCGACAGCACCCCGGAAGCCGTGGCCTGCCTGCTGGACAAGCAGATCGACGGTTTTGGCGAACTGTT
CCGCGCCATCTCGATTCTCGACATCGGCACCTCGACCGTACAAAGCCGTGCGCTGGCGGGCTTGTCCAACTGCACGCTGG
TGTGCTGCCTGCCGGGCTCCACTGGCGCTTGCCGCACCGCGTGGGAAGGCATCCTCGCCGAACAACTGGATAACCGTCAT
CGCCCTTGCAACTTCGTTCCGCACCTCAAACCGGTGCAAGCCTGCGGGCCGCGCGGATGA

Upstream 100 bases:

>100_bases
AGAGCAGGTCGATAGTGTGGTTGGCCAGAGTGATTAGACAGTCCTCACAAGCGGCACTTAGGCTCGTCATCCATTGAATT
GACGACGGCCGGAGAGTGCC

Downstream 100 bases:

>100_bases
GCAAGCCGGGGTTGATGCCGGTCGAGGACGCCCTCGACCAACTGTTGGCGATGGCCGATGAACAACGTCTACCGGACAGC
GAATCGGTGCCGCTCAATGA

Product: molybdopterin biosynthetic protein B2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSVKSDALFVPLNIAVLTVSDTRDYASDTSGQLLVSRLLEAGHTLSERNLLKDDLYKIRAQVAHWIADDNIQVVLITGGT
GFTGRDSTPEAVACLLDKQIDGFGELFRAISILDIGTSTVQSRALAGLSNCTLVCCLPGSTGACRTAWEGILAEQLDNRH
RPCNFVPHLKPVQACGPRG

Sequences:

>Translated_179_residues
MSVKSDALFVPLNIAVLTVSDTRDYASDTSGQLLVSRLLEAGHTLSERNLLKDDLYKIRAQVAHWIADDNIQVVLITGGT
GFTGRDSTPEAVACLLDKQIDGFGELFRAISILDIGTSTVQSRALAGLSNCTLVCCLPGSTGACRTAWEGILAEQLDNRH
RPCNFVPHLKPVQACGPRG
>Mature_178_residues
SVKSDALFVPLNIAVLTVSDTRDYASDTSGQLLVSRLLEAGHTLSERNLLKDDLYKIRAQVAHWIADDNIQVVLITGGTG
FTGRDSTPEAVACLLDKQIDGFGELFRAISILDIGTSTVQSRALAGLSNCTLVCCLPGSTGACRTAWEGILAEQLDNRHR
PCNFVPHLKPVQACGPRG

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1787000, Length=162, Percent_Identity=57.4074074074074, Blast_Score=200, Evalue=4e-53,
Organism=Drosophila melanogaster, GI17136978, Length=145, Percent_Identity=34.4827586206897, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638841, Length=145, Percent_Identity=34.4827586206897, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19208; Mature: 19077

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSDALFVPLNIAVLTVSDTRDYASDTSGQLLVSRLLEAGHTLSERNLLKDDLYKIRA
CCCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QVAHWIADDNIQVVLITGGTGFTGRDSTPEAVACLLDKQIDGFGELFRAISILDIGTSTV
HHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
QSRALAGLSNCTLVCCLPGSTGACRTAWEGILAEQLDNRHRPCNFVPHLKPVQACGPRG
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure 
SVKSDALFVPLNIAVLTVSDTRDYASDTSGQLLVSRLLEAGHTLSERNLLKDDLYKIRA
CCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QVAHWIADDNIQVVLITGGTGFTGRDSTPEAVACLLDKQIDGFGELFRAISILDIGTSTV
HHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
QSRALAGLSNCTLVCCLPGSTGACRTAWEGILAEQLDNRHRPCNFVPHLKPVQACGPRG
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]