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The map label for this gene is scoA [H]

Identifier: 77458303

GI number: 77458303

Start: 2361295

End: 2361993

Strand: Reverse

Name: scoA [H]

Synonym: Pfl01_2076

Alternate gene names: 77458303

Gene position: 2361993-2361295 (Counterclockwise)

Preceding gene: 77458305

Following gene: 77458302

Centisome position: 36.69

GC content: 60.8

Gene sequence:

>699_bases
ATGGCAGGTTTCGACAAGCGCGTGTATTCCTACGAGGAAGCCATGGCAGGTCTTGAAGACGGCATGACCGTAATCGCCGG
CGGCTTCGGCCTGTGCGGCATCCCGGAAAACCTGATCGCCGAGATCAAGCGCAAGGGCACCCGCGACCTCACCGTCGTCT
CCAACAACTGCGGCGTTGATGGCTTCGGCCTCGGCGTGCTGCTGACCGACCGCCAGATCAGCAAGGTGGTCGCCTCCTAC
GTCGGCGAAAACAAACTGTTCGAAGAGCAACTGCTCAAAGGCGACATCGAAGTCGTACTGACCCCGCAAGGCACCCTCGC
CGAGAAAATGCGCGCAGGCGGCGCCGGCATCCCGGCGTTCTTCACGGCTACTGGCGTCGGCACCCCGGTCGCCGAAGGCA
AGGAAGTACGTGAATTCCACGGTCGCAAGTACCTGATGGAAGAGTCCATCACCGGCGACTTCGCCATCGTCAAAGGCTGG
AAAGCCGACCATTTCGGCAACGTCATCTACCGCCACACCGCGCAGAACTTCAACCCGCTGGCCGCCACTGCCGGCAAGAT
CACCGTGGTCGAAGTCGAAGAAATCGTCGAACCCGGCGAGCTGGATCCCGCACACATCCACACGCCCGGCATCTACGTCG
ACCGGGTCATTTGCGGCACGTTCGAAAAACGCATCGAACAACGCACCATCCGCAAATAA

Upstream 100 bases:

>100_bases
TCAATCAACCTTAAAAATCAACTTAACAAATATATCCTTCAGCGCGACACTCCAGTCATTCGGCTAGCCAGCCGCCCGAC
AAACAATAAAAGAGGTGCAT

Downstream 100 bases:

>100_bases
TCCAGGCTGACGGAGAACAAGAACATGGCACTTACCCGCGAACAAATGGCTCAACGCGTCGCCCGCGAAATGCAGGACGG
CTACTACGTTAACCTCGGCA

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAGFDKRVYSYEEAMAGLEDGMTVIAGGFGLCGIPENLIAEIKRKGTRDLTVVSNNCGVDGFGLGVLLTDRQISKVVASY
VGENKLFEEQLLKGDIEVVLTPQGTLAEKMRAGGAGIPAFFTATGVGTPVAEGKEVREFHGRKYLMEESITGDFAIVKGW
KADHFGNVIYRHTAQNFNPLAATAGKITVVEVEEIVEPGELDPAHIHTPGIYVDRVICGTFEKRIEQRTIRK

Sequences:

>Translated_232_residues
MAGFDKRVYSYEEAMAGLEDGMTVIAGGFGLCGIPENLIAEIKRKGTRDLTVVSNNCGVDGFGLGVLLTDRQISKVVASY
VGENKLFEEQLLKGDIEVVLTPQGTLAEKMRAGGAGIPAFFTATGVGTPVAEGKEVREFHGRKYLMEESITGDFAIVKGW
KADHFGNVIYRHTAQNFNPLAATAGKITVVEVEEIVEPGELDPAHIHTPGIYVDRVICGTFEKRIEQRTIRK
>Mature_231_residues
AGFDKRVYSYEEAMAGLEDGMTVIAGGFGLCGIPENLIAEIKRKGTRDLTVVSNNCGVDGFGLGVLLTDRQISKVVASYV
GENKLFEEQLLKGDIEVVLTPQGTLAEKMRAGGAGIPAFFTATGVGTPVAEGKEVREFHGRKYLMEESITGDFAIVKGWK
ADHFGNVIYRHTAQNFNPLAATAGKITVVEVEEIVEPGELDPAHIHTPGIYVDRVICGTFEKRIEQRTIRK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=239, Percent_Identity=56.4853556485356, Blast_Score=261, Evalue=3e-70,
Organism=Homo sapiens, GI11545841, Length=239, Percent_Identity=55.6485355648536, Blast_Score=240, Evalue=9e-64,
Organism=Escherichia coli, GI1788551, Length=217, Percent_Identity=40.5529953917051, Blast_Score=185, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=239, Percent_Identity=50.6276150627615, Blast_Score=243, Evalue=7e-65,
Organism=Drosophila melanogaster, GI21358325, Length=244, Percent_Identity=51.2295081967213, Blast_Score=237, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24655794, Length=244, Percent_Identity=51.2295081967213, Blast_Score=237, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25190; Mature: 25059

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFDKRVYSYEEAMAGLEDGMTVIAGGFGLCGIPENLIAEIKRKGTRDLTVVSNNCGVD
CCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
GFGLGVLLTDRQISKVVASYVGENKLFEEQLLKGDIEVVLTPQGTLAEKMRAGGAGIPAF
CCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHH
FTATGVGTPVAEGKEVREFHGRKYLMEESITGDFAIVKGWKADHFGNVIYRHTAQNFNPL
EEECCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEEEECCCCCHHCCEEEEECCCCCCCC
AATAGKITVVEVEEIVEPGELDPAHIHTPGIYVDRVICGTFEKRIEQRTIRK
CCCCCCEEEEEHHHHCCCCCCCCCEEECCCEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGFDKRVYSYEEAMAGLEDGMTVIAGGFGLCGIPENLIAEIKRKGTRDLTVVSNNCGVD
CCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
GFGLGVLLTDRQISKVVASYVGENKLFEEQLLKGDIEVVLTPQGTLAEKMRAGGAGIPAF
CCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHH
FTATGVGTPVAEGKEVREFHGRKYLMEESITGDFAIVKGWKADHFGNVIYRHTAQNFNPL
EEECCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEEEECCCCCHHCCEEEEECCCCCCCC
AATAGKITVVEVEEIVEPGELDPAHIHTPGIYVDRVICGTFEKRIEQRTIRK
CCCCCCEEEEEHHHHCCCCCCCCCEEECCCEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]