Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 77458276

GI number: 77458276

Start: 2335914

End: 2336987

Strand: Direct

Name: adrA [H]

Synonym: Pfl01_2049

Alternate gene names: 77458276

Gene position: 2335914-2336987 (Clockwise)

Preceding gene: 77458261

Following gene: 77458277

Centisome position: 36.28

GC content: 60.71

Gene sequence:

>1074_bases
ATGGGAAGAACGGGAGGAAAGGGACTTTCACTGGCCAGGAGGCTCTATGCATCGCGAATCCTCGGGCTGGTCCTGGGGCT
TTTGTGCGTGAGCGTCGCGATGTACCCGCTCGATCCCCCCGCCTGGGTCTGGGCGCTGATGCTGTTCAACGGCCTGGTCT
GGCCACACCTTGCTTATCAATGGGCTCGTCGGGCGAAGGTTCCTTACCACGCCGAACACCGCAATCTGTTGATCGATGCT
TTTCTCGGTGGCTTCTGGGTGGCGGCCATGCACTTCAATCCCTTGCCCAGTGCCACGACCATTTCGATGATGGCGATGAA
CAACGTCGCCATCGGTGGATTACGTTTTCTACTGGCCGGGGCGGCGGCGCAGTTGCTTGGCGTCGGTGTCGGGCTGGTGG
TGTTTGCCCCCGCGTTCGTCCCGATGACCACGCCGGCACAGCTTTATGCCTGTCTGCCGTTGTTGACGCTGTATCCGCTG
GCGCTGGGCTGGATCTGCTTTCGCCAGGCCTACACCCTCGGCTTGCATAAACGTGAACTTCTGGCTTTGAGCCGCACCGA
CAGCCTCACCGGTCTGCTCAATCACGGCGCCTGGAAGGATCAACTGGAAATCGAATTCGAACGCTGCAAACGTCAGCAGA
CCGGTGCCGCGATTGCGCTGATCGACATCGACCACTTCAAGGCGATCAACGACACCTACGGCCACGTGGCCGGCGATATC
GTTCTGCGTCAACTGAGCAAGATGCTCAAGCAGAACCTGCGCATGGCCGATGTGGCGGGGCGCTACGGCGGTGACGAGTT
CTGCGTGATCCTGCCGGACTTGCCGCTGTTCAATGCGGCGCAGGCGATGGAAGCGTTGCGTGAGCGTTTTTCCTTTCTGG
TGTACGAACAGAACCCGGCGCTGAAAGTCAGCCTGAGCATCGGTCTGGCGGCGCTCGATCCGGCACACGGCGACGCGACG
CGCTGGCTCGATGACGCCGATCAGGCACTGTATGAAGCCAAGGCCGGCGGACGTAACCGGGTGATTTGCTGCAGCGATAA
CAACCCGCGCCGCGAGGTATTCGATTCGGTTTGA

Upstream 100 bases:

>100_bases
CGGCCCGCTGGCCGGTGATGGCTATTTAACGTTGCCCTGATAGACTCCCAGCACATCCGGTCTGCGGTCTGCGCAATGCC
GTCGAGTGGTCGAGGCCCTT

Downstream 100 bases:

>100_bases
ACAGATCGGGTGTCGCATCGGGGATAGAGCCTTGGGCGGATGTCAGGTACGGTTCAGTACCCGACACGAAACAAGGATTG
ATTCATGACGTTCAAATTCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MGRTGGKGLSLARRLYASRILGLVLGLLCVSVAMYPLDPPAWVWALMLFNGLVWPHLAYQWARRAKVPYHAEHRNLLIDA
FLGGFWVAAMHFNPLPSATTISMMAMNNVAIGGLRFLLAGAAAQLLGVGVGLVVFAPAFVPMTTPAQLYACLPLLTLYPL
ALGWICFRQAYTLGLHKRELLALSRTDSLTGLLNHGAWKDQLEIEFERCKRQQTGAAIALIDIDHFKAINDTYGHVAGDI
VLRQLSKMLKQNLRMADVAGRYGGDEFCVILPDLPLFNAAQAMEALRERFSFLVYEQNPALKVSLSIGLAALDPAHGDAT
RWLDDADQALYEAKAGGRNRVICCSDNNPRREVFDSV

Sequences:

>Translated_357_residues
MGRTGGKGLSLARRLYASRILGLVLGLLCVSVAMYPLDPPAWVWALMLFNGLVWPHLAYQWARRAKVPYHAEHRNLLIDA
FLGGFWVAAMHFNPLPSATTISMMAMNNVAIGGLRFLLAGAAAQLLGVGVGLVVFAPAFVPMTTPAQLYACLPLLTLYPL
ALGWICFRQAYTLGLHKRELLALSRTDSLTGLLNHGAWKDQLEIEFERCKRQQTGAAIALIDIDHFKAINDTYGHVAGDI
VLRQLSKMLKQNLRMADVAGRYGGDEFCVILPDLPLFNAAQAMEALRERFSFLVYEQNPALKVSLSIGLAALDPAHGDAT
RWLDDADQALYEAKAGGRNRVICCSDNNPRREVFDSV
>Mature_356_residues
GRTGGKGLSLARRLYASRILGLVLGLLCVSVAMYPLDPPAWVWALMLFNGLVWPHLAYQWARRAKVPYHAEHRNLLIDAF
LGGFWVAAMHFNPLPSATTISMMAMNNVAIGGLRFLLAGAAAQLLGVGVGLVVFAPAFVPMTTPAQLYACLPLLTLYPLA
LGWICFRQAYTLGLHKRELLALSRTDSLTGLLNHGAWKDQLEIEFERCKRQQTGAAIALIDIDHFKAINDTYGHVAGDIV
LRQLSKMLKQNLRMADVAGRYGGDEFCVILPDLPLFNAAQAMEALRERFSFLVYEQNPALKVSLSIGLAALDPAHGDATR
WLDDADQALYEAKAGGRNRVICCSDNNPRREVFDSV

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=335, Percent_Identity=38.2089552238806, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=39.0243902439024, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=39.4904458598726, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788381, Length=198, Percent_Identity=33.8383838383838, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=33.5365853658537, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081977, Length=160, Percent_Identity=37.5, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787541, Length=186, Percent_Identity=33.8709677419355, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081974, Length=172, Percent_Identity=33.1395348837209, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=34.4827586206897, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=135, Percent_Identity=30.3703703703704, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=33.5443037974684, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=32.0512820512821, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 39277; Mature: 39146

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTGGKGLSLARRLYASRILGLVLGLLCVSVAMYPLDPPAWVWALMLFNGLVWPHLAYQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
WARRAKVPYHAEHRNLLIDAFLGGFWVAAMHFNPLPSATTISMMAMNNVAIGGLRFLLAG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
AAAQLLGVGVGLVVFAPAFVPMTTPAQLYACLPLLTLYPLALGWICFRQAYTLGLHKREL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LALSRTDSLTGLLNHGAWKDQLEIEFERCKRQQTGAAIALIDIDHFKAINDTYGHVAGDI
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCHHCCCEEEEEECHHHHHHCHHHHHHHHHH
VLRQLSKMLKQNLRMADVAGRYGGDEFCVILPDLPLFNAAQAMEALRERFSFLVYEQNPA
HHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCC
LKVSLSIGLAALDPAHGDATRWLDDADQALYEAKAGGRNRVICCSDNNPRREVFDSV
EEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCC
>Mature Secondary Structure 
GRTGGKGLSLARRLYASRILGLVLGLLCVSVAMYPLDPPAWVWALMLFNGLVWPHLAYQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
WARRAKVPYHAEHRNLLIDAFLGGFWVAAMHFNPLPSATTISMMAMNNVAIGGLRFLLAG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
AAAQLLGVGVGLVVFAPAFVPMTTPAQLYACLPLLTLYPLALGWICFRQAYTLGLHKREL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LALSRTDSLTGLLNHGAWKDQLEIEFERCKRQQTGAAIALIDIDHFKAINDTYGHVAGDI
HHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCHHCCCEEEEEECHHHHHHCHHHHHHHHHH
VLRQLSKMLKQNLRMADVAGRYGGDEFCVILPDLPLFNAAQAMEALRERFSFLVYEQNPA
HHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCC
LKVSLSIGLAALDPAHGDATRWLDDADQALYEAKAGGRNRVICCSDNNPRREVFDSV
EEEEEEECEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]