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The map label for this gene is 77458275

Identifier: 77458275

GI number: 77458275

Start: 2334269

End: 2335723

Strand: Reverse

Name: 77458275

Synonym: Pfl01_2048

Alternate gene names: NA

Gene position: 2335723-2334269 (Counterclockwise)

Preceding gene: 77458279

Following gene: 77458274

Centisome position: 36.28

GC content: 59.18

Gene sequence:

>1455_bases
ATGCAGACCTACCAAGTGTTGATTATCGGCAGCGGTTTTGGCGGCCAGTGCGCGGCGGTCAACCTGCTCAAGGCCGGTAT
CGACGACTTTCGCTTGCTGGAGCGCCGGGACTTTTTCGGTGGCACCTGGTGCCAGAACACCTACCCCGGCGCAGCGGTGG
ATGTGCCGTCGCCGCTGTATTCCTTGTCATTTGCGCCTTATCGCTGGACGCAGATGTTCGCCGAACAGGCCGAACTGCAC
CGCTACACCGACCATGTAATCGAACGCTTCGGCCTGCGCGATCGGGTGGAACTGGAGGCCAACGTCGAACGCGTCGAATG
GGACGACACCGAAAAACGCTGGGCCGTACACACTGGCACCAAAGGCATTTTTTATGCGCAGTTCCTGATCAATGCCACCG
GGCCGTTGAGCCAACCGGTTATCCCACACTTCCCCGGTCAGGATCGCTTTCAGGGCAAGACCTTTCATACAAACAATTGG
GATCACAGCTACGACTATCACGGTAAACGGGTAGCGATTGTCGGCAGCGGTGCCAGTGCGGCTCAGGTGATTCCGGCGAT
TGCACCGAAGGTCGCCCATTTGCATGTGTTTCAGCGCACCGCGCATTGGGTGCTGCCCCGGGCCGACCGTACATTCGGGC
GGTTCCAGCGCTGGTTGCTGGGTCTGAAACCGGCCTACAAACTGCTGCGCTGGATGATCTACTGGCAATTCGAAACCCGG
GTCATCGCCTTCAAATACTCGAAACCGGCGATTCACATGGTGCAGCGACACGCCCTGAAGTTTCTCAAGCGCCAGGTAAC
TGACCCCGAACTGCGGAAAAAACTCACACCGGACTTCACCATCGGCTGCAAACGGGTATTGGTCTCCAGTACCTACTATC
CGGCGCTGACCCGGCCCAACGTCACGCTGCACAGCCGCGAACAGGGCATCGCCAGCCTCGACGAAACCGGCATCATCACC
ACGGACGGCCAGCACATCGACGTCGATCTGATCGTCTGGTCGACCGGTTACGACGCCACCGACGGCGTGATTTCCTACCC
GGTCAGCGGAAAAAACGCCGTGCAACTGCGCGACGTGTGGGCGCAATACCCGCGCGCCTACCTCGGCACCAGCCTGCCGG
ACTTTCCCAACCTGTTTATCGTCACCGGGCCGAACACCGGCATCGGGCATACGTCGGCGCTGTTCATCATCGAATCGCAG
ATGAACTACATCCTCGACTGCATCCGCACCGTGCAGGCCAAAGGTCTGCGCAGCATCGAAGTTCGCCCCGAAGCAGAACG
TACCTACACTCAGATGATTCACCGGGAAATGGAACGCACGGTCTGGAAAACCGGCGGCTGCCACAGTTGGTATCAAAGCA
GGAGCGGTCATGTGATCGCGATGTTTCCCGGCTTCAGTTTCAGCTATCACCGGTTGACCCGGGCGCTGAAACCGGCCGAC
CACATTCTGTCTTGA

Upstream 100 bases:

>100_bases
CAGCGGGCCGAATACCCCGTCATCAGCACCACACGGCAGGCAAATGATTGGCTATACATGAAAGGATGAAAATGGAAAAA
AGACTCTAAGAAGGAGGCCC

Downstream 100 bases:

>100_bases
ACAAGGAAGACCCACGATGCTTTTGTTGTTTGTCGCCCTCGCGGTTTTCGTGGCCTGGAGCTGGTTGAGTTACCCGGCGG
TCGGCCACTGGCTCTACGAT

Product: flavin-containing monooxygenase FMO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MQTYQVLIIGSGFGGQCAAVNLLKAGIDDFRLLERRDFFGGTWCQNTYPGAAVDVPSPLYSLSFAPYRWTQMFAEQAELH
RYTDHVIERFGLRDRVELEANVERVEWDDTEKRWAVHTGTKGIFYAQFLINATGPLSQPVIPHFPGQDRFQGKTFHTNNW
DHSYDYHGKRVAIVGSGASAAQVIPAIAPKVAHLHVFQRTAHWVLPRADRTFGRFQRWLLGLKPAYKLLRWMIYWQFETR
VIAFKYSKPAIHMVQRHALKFLKRQVTDPELRKKLTPDFTIGCKRVLVSSTYYPALTRPNVTLHSREQGIASLDETGIIT
TDGQHIDVDLIVWSTGYDATDGVISYPVSGKNAVQLRDVWAQYPRAYLGTSLPDFPNLFIVTGPNTGIGHTSALFIIESQ
MNYILDCIRTVQAKGLRSIEVRPEAERTYTQMIHREMERTVWKTGGCHSWYQSRSGHVIAMFPGFSFSYHRLTRALKPAD
HILS

Sequences:

>Translated_484_residues
MQTYQVLIIGSGFGGQCAAVNLLKAGIDDFRLLERRDFFGGTWCQNTYPGAAVDVPSPLYSLSFAPYRWTQMFAEQAELH
RYTDHVIERFGLRDRVELEANVERVEWDDTEKRWAVHTGTKGIFYAQFLINATGPLSQPVIPHFPGQDRFQGKTFHTNNW
DHSYDYHGKRVAIVGSGASAAQVIPAIAPKVAHLHVFQRTAHWVLPRADRTFGRFQRWLLGLKPAYKLLRWMIYWQFETR
VIAFKYSKPAIHMVQRHALKFLKRQVTDPELRKKLTPDFTIGCKRVLVSSTYYPALTRPNVTLHSREQGIASLDETGIIT
TDGQHIDVDLIVWSTGYDATDGVISYPVSGKNAVQLRDVWAQYPRAYLGTSLPDFPNLFIVTGPNTGIGHTSALFIIESQ
MNYILDCIRTVQAKGLRSIEVRPEAERTYTQMIHREMERTVWKTGGCHSWYQSRSGHVIAMFPGFSFSYHRLTRALKPAD
HILS
>Mature_484_residues
MQTYQVLIIGSGFGGQCAAVNLLKAGIDDFRLLERRDFFGGTWCQNTYPGAAVDVPSPLYSLSFAPYRWTQMFAEQAELH
RYTDHVIERFGLRDRVELEANVERVEWDDTEKRWAVHTGTKGIFYAQFLINATGPLSQPVIPHFPGQDRFQGKTFHTNNW
DHSYDYHGKRVAIVGSGASAAQVIPAIAPKVAHLHVFQRTAHWVLPRADRTFGRFQRWLLGLKPAYKLLRWMIYWQFETR
VIAFKYSKPAIHMVQRHALKFLKRQVTDPELRKKLTPDFTIGCKRVLVSSTYYPALTRPNVTLHSREQGIASLDETGIIT
TDGQHIDVDLIVWSTGYDATDGVISYPVSGKNAVQLRDVWAQYPRAYLGTSLPDFPNLFIVTGPNTGIGHTSALFIIESQ
MNYILDCIRTVQAKGLRSIEVRPEAERTYTQMIHREMERTVWKTGGCHSWYQSRSGHVIAMFPGFSFSYHRLTRALKPAD
HILS

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=381, Percent_Identity=21.7847769028871, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561948, Length=359, Percent_Identity=22.0055710306407, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145785, Length=366, Percent_Identity=21.5846994535519, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921694, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55281; Mature: 55281

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTYQVLIIGSGFGGQCAAVNLLKAGIDDFRLLERRDFFGGTWCQNTYPGAAVDVPSPLY
CCEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHH
SLSFAPYRWTQMFAEQAELHRYTDHVIERFGLRDRVELEANVERVEWDDTEKRWAVHTGT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCEEEEECCC
KGIFYAQFLINATGPLSQPVIPHFPGQDRFQGKTFHTNNWDHSYDYHGKRVAIVGSGASA
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCH
AQVIPAIAPKVAHLHVFQRTAHWVLPRADRTFGRFQRWLLGLKPAYKLLRWMIYWQFETR
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEE
VIAFKYSKPAIHMVQRHALKFLKRQVTDPELRKKLTPDFTIGCKRVLVSSTYYPALTRPN
EEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
VTLHSREQGIASLDETGIITTDGQHIDVDLIVWSTGYDATDGVISYPVSGKNAVQLRDVW
CEEECCCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHH
AQYPRAYLGTSLPDFPNLFIVTGPNTGIGHTSALFIIESQMNYILDCIRTVQAKGLRSIE
HHCCHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEE
VRPEAERTYTQMIHREMERTVWKTGGCHSWYQSRSGHVIAMFPGFSFSYHRLTRALKPAD
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHH
HILS
HHCC
>Mature Secondary Structure
MQTYQVLIIGSGFGGQCAAVNLLKAGIDDFRLLERRDFFGGTWCQNTYPGAAVDVPSPLY
CCEEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCHH
SLSFAPYRWTQMFAEQAELHRYTDHVIERFGLRDRVELEANVERVEWDDTEKRWAVHTGT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCEEEEECCC
KGIFYAQFLINATGPLSQPVIPHFPGQDRFQGKTFHTNNWDHSYDYHGKRVAIVGSGASA
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCH
AQVIPAIAPKVAHLHVFQRTAHWVLPRADRTFGRFQRWLLGLKPAYKLLRWMIYWQFETR
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEE
VIAFKYSKPAIHMVQRHALKFLKRQVTDPELRKKLTPDFTIGCKRVLVSSTYYPALTRPN
EEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
VTLHSREQGIASLDETGIITTDGQHIDVDLIVWSTGYDATDGVISYPVSGKNAVQLRDVW
CEEECCCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHH
AQYPRAYLGTSLPDFPNLFIVTGPNTGIGHTSALFIIESQMNYILDCIRTVQAKGLRSIE
HHCCHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEE
VRPEAERTYTQMIHREMERTVWKTGGCHSWYQSRSGHVIAMFPGFSFSYHRLTRALKPAD
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHH
HILS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]