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The map label for this gene is pgaC [H]

Identifier: 77458243

GI number: 77458243

Start: 2298637

End: 2299773

Strand: Reverse

Name: pgaC [H]

Synonym: Pfl01_2016

Alternate gene names: 77458243

Gene position: 2299773-2298637 (Counterclockwise)

Preceding gene: 77458244

Following gene: 77458242

Centisome position: 35.72

GC content: 63.94

Gene sequence:

>1137_bases
GTGGCTGAATTCATTTTCTGGATGTGCCTGCTGCTGCCGGCGTACGCCTATGTCGGCTATCCACTGCTGCTGACGCTGCT
GGCGCCACTGTTTCCGGCGTGGCGCCACAGCCCGGCCCCGCCGCTGAACGTCAGCATCGTCATTGCCGCCCACAATGAAG
CACGGCACATCGAACACAAGCTGCGCTCGCTGCTGTCCCAGGATTATCAGCCGGCGACCCTGCAAATCATTCTGGCCAGC
GACGGTTCCACCGACGCCACCGTGGCCTGCGCACACAAGGTCGTCGACCCGCGAATCACCGTGCTCGACCTGCCCCGCCA
GGGCAAAGCCGCCACGCTGAATGCCGGCGCGGCCCTGGCCACGGGCGACATTCTGGTGTTCACCGACGCTGATAACCAAT
GGTCGCGGGAAACCCTCGGCTACCTGCTGGCGCCGCTGAGCGATCCGCAGGTCGGCGCCTGCGCCGGGCACATGGTGATT
CCGGTCACCGGTGGCGGACTGAGCATCGGCGACAGCCTTTATCGGCACTACGAGGGCTGGTTGCGCCGGGTCGAGAACCG
TACCGGCTGCATGGTCTCCGCCGACGGCGCCCTGCTCGCCCTGCGCCGCGAACTGTTCGAGAACGTGCCGGCCGAGGTCA
ATGACGACTTTTTCATCAGCACCTGCGCGCCAGTGAAATTCAAACGCATCGTCTACGTGCCCGAAGCGCAAGTGATCGAC
CACGGCGTCGACGAAGCGGACAAGCAATTCCGCCGGCGCCAGCGGGTCACGGTCGGCGGCCTGCAAAGCCTGGCGCAACG
CAGTGAACTGCTTAATCCGTTCAAGCATGGGCTGTATTCGATTGCGTTGATCAGCCACAAGCTGATCCGCCGTCTGGCGC
CGATCCTGTTGCTGCCGCTGCTGCTGAGCAATTTCTGGCTGTGGGAAGACCACGGTTTCTATCGCCTGAGCCTGATCGCG
CAACTGATCGGCTACGCCATTGCGATTGCCGGTCTGCTGGATTCGCAGCACCGCTTGCCCAAGCCGTTCCGCCTCGCGGC
GTTCCTGCTGGTGACACTGGCGGGCACGAGCATCGGCCTGTGGCAGTTCCTGCGCGGCCAGCGTTATGCCCAGTGGAACC
CTGACCAAAACCGTTGA

Upstream 100 bases:

>100_bases
CTGACCCTGCAACTGTGGGGTCTGCACTGGGTGCGCCTGCACCTGGCGGGCGCGGCGTTCATTCTCAGTCTGTGTCATTG
GAACGCCAGGAGGCCTGCCC

Downstream 100 bases:

>100_bases
GAGGGATCGAGCCATGGCGATCAAACAACTGATTAAACGCACCAGCGGCTGGCTCTATCTAAACTCGTCCGTGGGACGCA
ACCAGTTGCAAGGCGCAGGT

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MAEFIFWMCLLLPAYAYVGYPLLLTLLAPLFPAWRHSPAPPLNVSIVIAAHNEARHIEHKLRSLLSQDYQPATLQIILAS
DGSTDATVACAHKVVDPRITVLDLPRQGKAATLNAGAALATGDILVFTDADNQWSRETLGYLLAPLSDPQVGACAGHMVI
PVTGGGLSIGDSLYRHYEGWLRRVENRTGCMVSADGALLALRRELFENVPAEVNDDFFISTCAPVKFKRIVYVPEAQVID
HGVDEADKQFRRRQRVTVGGLQSLAQRSELLNPFKHGLYSIALISHKLIRRLAPILLLPLLLSNFWLWEDHGFYRLSLIA
QLIGYAIAIAGLLDSQHRLPKPFRLAAFLLVTLAGTSIGLWQFLRGQRYAQWNPDQNR

Sequences:

>Translated_378_residues
MAEFIFWMCLLLPAYAYVGYPLLLTLLAPLFPAWRHSPAPPLNVSIVIAAHNEARHIEHKLRSLLSQDYQPATLQIILAS
DGSTDATVACAHKVVDPRITVLDLPRQGKAATLNAGAALATGDILVFTDADNQWSRETLGYLLAPLSDPQVGACAGHMVI
PVTGGGLSIGDSLYRHYEGWLRRVENRTGCMVSADGALLALRRELFENVPAEVNDDFFISTCAPVKFKRIVYVPEAQVID
HGVDEADKQFRRRQRVTVGGLQSLAQRSELLNPFKHGLYSIALISHKLIRRLAPILLLPLLLSNFWLWEDHGFYRLSLIA
QLIGYAIAIAGLLDSQHRLPKPFRLAAFLLVTLAGTSIGLWQFLRGQRYAQWNPDQNR
>Mature_377_residues
AEFIFWMCLLLPAYAYVGYPLLLTLLAPLFPAWRHSPAPPLNVSIVIAAHNEARHIEHKLRSLLSQDYQPATLQIILASD
GSTDATVACAHKVVDPRITVLDLPRQGKAATLNAGAALATGDILVFTDADNQWSRETLGYLLAPLSDPQVGACAGHMVIP
VTGGGLSIGDSLYRHYEGWLRRVENRTGCMVSADGALLALRRELFENVPAEVNDDFFISTCAPVKFKRIVYVPEAQVIDH
GVDEADKQFRRRQRVTVGGLQSLAQRSELLNPFKHGLYSIALISHKLIRRLAPILLLPLLLSNFWLWEDHGFYRLSLIAQ
LIGYAIAIAGLLDSQHRLPKPFRLAAFLLVTLAGTSIGLWQFLRGQRYAQWNPDQNR

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=277, Percent_Identity=27.0758122743682, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 42012; Mature: 41881

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFIFWMCLLLPAYAYVGYPLLLTLLAPLFPAWRHSPAPPLNVSIVIAAHNEARHIEHK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHH
LRSLLSQDYQPATLQIILASDGSTDATVACAHKVVDPRITVLDLPRQGKAATLNAGAALA
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCEEE
TGDILVFTDADNQWSRETLGYLLAPLSDPQVGACAGHMVIPVTGGGLSIGDSLYRHYEGW
ECCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
LRRVENRTGCMVSADGALLALRRELFENVPAEVNDDFFISTCAPVKFKRIVYVPEAQVID
HHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCHHHHH
HGVDEADKQFRRRQRVTVGGLQSLAQRSELLNPFKHGLYSIALISHKLIRRLAPILLLPL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSNFWLWEDHGFYRLSLIAQLIGYAIAIAGLLDSQHRLPKPFRLAAFLLVTLAGTSIGL
HHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
WQFLRGQRYAQWNPDQNR
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEFIFWMCLLLPAYAYVGYPLLLTLLAPLFPAWRHSPAPPLNVSIVIAAHNEARHIEHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHH
LRSLLSQDYQPATLQIILASDGSTDATVACAHKVVDPRITVLDLPRQGKAATLNAGAALA
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCEEE
TGDILVFTDADNQWSRETLGYLLAPLSDPQVGACAGHMVIPVTGGGLSIGDSLYRHYEGW
ECCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
LRRVENRTGCMVSADGALLALRRELFENVPAEVNDDFFISTCAPVKFKRIVYVPEAQVID
HHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCHHHHH
HGVDEADKQFRRRQRVTVGGLQSLAQRSELLNPFKHGLYSIALISHKLIRRLAPILLLPL
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSNFWLWEDHGFYRLSLIAQLIGYAIAIAGLLDSQHRLPKPFRLAAFLLVTLAGTSIGL
HHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
WQFLRGQRYAQWNPDQNR
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]